Abstract:
:Supine and standing heart rate and heart rate responses to deep breathing and standing up (the 30-to-15 ratio), indices of autonomic nervous function, were measured during each trimester and postpartum in 25 women with insulin-dependent diabetes and 10 nondiabetic women. The groups did not differ with respect to autonomic function in the basal state (postpartum), and the heart rate response to deep breathing diminished progressively in both groups during pregnancy, although the change tended to be less pronounced in the diabetic women. The 30-to-15 ratio did not alter significantly during pregnancy. The diabetic women had a higher supine heart rate than the healthy women in the basal state, but the pregnancy-induced increase in heart rate was less in the diabetic women. Thus, the reversible diminution of heart rate response to deep breathing during pregnancy is a physiological finding and does not denote development of autonomic nervous dysfunction. Second, the increase in heart rate, a primary cardiovascular adjustment to pregnancy, seems to be blunted in diabetic women.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Airaksinen KE,Salmela PI,Ikäheimo MJ,Kirkinen P,Linnaluoto MK,Takkunen JTdoi
10.2337/diacare.10.6.748subject
Has Abstractpub_date
1987-11-01 00:00:00pages
748-51issue
6eissn
0149-5992issn
1935-5548journal_volume
10pub_type
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