Abstract:
:Agitation is a significant problem in the intensive care unit (ICU), affecting 71% of sedated adult patients during 58% of ICU patient-days (Fraser and Riker 2001 NY Health-Syst. Pharm. 20 17-24). Subjective scale-based assessment methods are currently used to assess the level of patient agitation, but are limited in their accuracy and resolution. This research develops an objective agitation measurement method using heart rate variability (HRV), systolic blood pressure (BP) and blood pressure variability (BPV) data, processed by wavelet transforms and autoregressive signal processing. A fuzzy inference system (FIS) is developed to classify changes in these signals that correlate with observed patient agitation, and combine them into a final agitation level. Proof of concept clinical trials on 13 normal subjects and 5 ICU patients has been performed to verify the validity of this approach in comparison with agitation graded by nursing staff using the Riker sedation-agitation scale (SAS). Results show good correlation with medical staff assessment with no false positive results during calm periods. Clinically, this initial agitation measurement method promises the ability to consistently and objectively quantify patient agitation to enable better management of sedation and agitation through optimized drug delivery leading to reduced length of stay.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Chase JG,Starfinger C,Lam Z,Agogue F,Shaw GMdoi
10.1088/0967-3334/25/4/020subject
Has Abstractpub_date
2004-08-01 00:00:00pages
1037-51issue
4eissn
0967-3334issn
1361-6579journal_volume
25pub_type
临床试验,杂志文章abstract::Conventional bioimpedance spectrometers measure resistance and reactance over a range of frequencies and, by application of a mathematical model for an equivalent circuit (the Cole model), estimate resistance at zero and infinite frequencies. Fitting of the experimental data to the model is accomplished by iterative, ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/9/007
更新日期:2006-09-01 00:00:00
abstract::Stroke is a major cause of disability within the western world. About 20% of strokes are a consequence of atheromatous narrowing of the origin of the internal carotid artery. Carotid endarterectomy has been shown to be an effective treatment for those with symptomatic and severe stenosis, provided the risk of death an...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/24/2/310
更新日期:2003-05-01 00:00:00
abstract::The aim of the study was to investigate whether body mass index (BMI) influences the estimation of extracellular volume (ECV) in hemodialysis (HD) patients when using segmental bioimpedance analysis (SBIA) compared to wrist-to-ankle bioimpedance analysis (WBIA) during HD with ultrafiltration (UF). Twenty five HD patie...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/26/2/009
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVE:Increased penetration of pulsatile power to the brain has been implicated in the pathogenesis of age-related cognitive dysfunction and dementia, a common comorbidity in patients with heart failure and preserved ejection fraction (HFpEF). However, there is a lack of knowledge on the effects of organic and inor...
journal_title:Physiological measurement
pub_type: 杂志文章,随机对照试验
doi:10.1088/1361-6579/aab2ef
更新日期:2018-04-20 00:00:00
abstract:OBJECTIVE:The aim of the study was to explore the feasibility of titrating tidal volume (V T) and positive end-expiratory pressure (PEEP) during one-lung ventilation (OLV) based on ventilation distribution and oxygenation. APPROACH:Twenty-four consecutive patients requiring intubation with a double-lumen tube and subs...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaaeb2
更新日期:2018-03-29 00:00:00
abstract::The outflow conductance (C(out)) of the cerebrospinal fluid (CSF) system is a parameter considered to be predictive in selection for hydrocephalus surgery. C(out) can be determined through an infusion test. A new apparatus for performing infusion tests in a standardized and automated way was developed. The objective w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/6/022
更新日期:2005-12-01 00:00:00
abstract::The heart rate responds dynamically to various intrinsic and environmental stimuli. The autonomic nervous system is said to play a major role in this response. Multifractal analysis offers a novel method to assess the response of cardiac interbeat intervals. Twenty-four hour ECG recordings of RR interbeat intervals (o...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/10/014
更新日期:2011-10-01 00:00:00
abstract::Pulmonary blood volume increase during systole was measured in patients by analysing chest images obtained during ECG gated radionuclide angiography examination. The difference in the total radiation counts between systole and diastole in regions of interest, which included the lungs and the left ventricle, was measur...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/15/4/010
更新日期:1994-11-01 00:00:00
abstract::The standard electrocardiogram (ECG) is the most common non-invasive way to study atrial fibrillation (AF). In this respect, previous works have shown that the surface lead V(1) reflects mainly the dominant atrial frequency (DAF) of the right atrium (RA), which has been widely used to study AF. In a similar way, AF or...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/1/007
更新日期:2011-01-01 00:00:00
abstract::Despite significant advances in adult clinical electrocardiography (ECG) signal processing techniques and the power of digital processors, the analysis of non-invasive foetal ECG (NI-FECG) is still in its infancy. The Physionet/Computing in Cardiology Challenge 2013 addresses some of these limitations by making a set ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/8/1569
更新日期:2014-08-01 00:00:00
abstract::The state-dependent portion of cardio-vagal baroreflex control is called baroreflex hyteresis: we observe hysteresis when RR interval and carotid diameter depend on both the direction and value of arterial pressure. The elasticity of arterial walls, as well as the responsiveness of central command reset controls the r...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/6/009
更新日期:2010-06-01 00:00:00
abstract::A time-varying parametric spectrum estimation method for analysing non-stationary heart rate variability signals is presented. As a case study, the dynamics of heart rate variability during an orthostatic test is examined. In this method, the non-stationary signal is first modelled with a time-varying autoregressive m...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/27/3/002
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Walking is a complex human behavior, usually performed in a dynamic environment. Gait parameters are thought to reflect this complexity. Re-Step™ is a therapy system in the form of a computerized shoe, originally developed for the training and rehabilitation of individuals with brain damage. Th...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/1361-6579/aab659
更新日期:2018-04-26 00:00:00
abstract::Electrical impedance tomography (EIT) measures the conductivity distribution within an object based on the current applied and voltage measured at surface electrodes. Thus, EIT images are sensitive to electrode properties (i.e. contact impedance, electrode area and boundary shape under the electrode). While some of th...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/7/S02
更新日期:2011-07-01 00:00:00
abstract::Gated SPECT (GSPECT) was evaluated for the measurement of left ventricular ejection fraction (LVEF) by comparing with equilibrium gated radionuclide ventriculography (RNVG). A total of 99 subjects underwent GSPECT and RNVG imaging. All studies were acquired in list mode with GSPECT studies processed to give 16- and 8-...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/22/2/312
更新日期:2001-05-01 00:00:00
abstract::Electrical impedance tomography (EIT) could be significantly advantageous to continuous monitoring of lung development in newborn and, in particular, preterm infants as it is non-invasive and safe to use within the intensive care unit. It has been demonstrated that accurate boundary form of the forward model is import...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/6/1149
更新日期:2014-06-01 00:00:00
abstract::In this study, a framework for the characterization of the dynamic interactions between RR variability (RRV) and systolic arterial pressure variability (SAPV) is proposed. The methodology accounts for the intrinsic non-stationarity of the cardiovascular system and includes the assessment of both the strength and the p...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/33/3/315
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:The creation of artificial gravity on board a space station is one of the promising methods for preventing health problems during space missions; a short-radius centrifuge (SRC) is the model of such a method on Earth. Our goal was to evaluate the sensitivity of bioimpedance polysegmental measurements for moni...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab840b
更新日期:2020-05-07 00:00:00
abstract::We investigated the utility of ICA for evaluation of fetal rhythm in five uncomplicated twin pregnancies and in five twin pregnancies complicated by fetal arrhythmia. Using objective and subjective criteria, we sought to determine how the signal-to-noise ratio, signal fidelity and interference rejection are affected w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/1/004
更新日期:2011-01-01 00:00:00
abstract::Electrical impedance tomography (EIT) image reconstruction is an ill-posed problem requiring maximum measurement precision. Recent EIT systems claim 60 to 80 dB precision. Achieving higher values is hard in practice since measurements must be performed at relatively high frequency, on a living subject, while using com...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/5/S05
更新日期:2006-05-01 00:00:00
abstract::We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using a double-indicator...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/17/4a/016
更新日期:1996-11-01 00:00:00
abstract::Capillary refill time (CRT) is a simple means of cardiovascular assessment which is widely used in clinical care. Currently, CRT is measured through manual assessment of the time taken for skin tone to return to normal colour following blanching of the skin surface. There is evidence to suggest that manually assessed ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/1/83
更新日期:2016-01-01 00:00:00
abstract::Tetrapolar linear arrays are commonly used in geophysics to explore the vertical distribution of resistivity values in a geological section of a specific point on the earth. This technique, known as vertical electric sounding (VES), uses different electrode configurations. For our experiments, we utilized its more pop...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/18/1/007
更新日期:1997-02-01 00:00:00
abstract::In this paper we present the concept, the design and the test procedure for a DSP-based high-precision and high-performance wide-band (up to 10 MHz) bioimpedance analyser module for application in EIT or bioimpedance spectroscopy. The module implements a digital concept with appropriate signal conditioning hardware fo...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/1/303
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:The ratio of the partial pressure of arterial oxygen to fraction of inspired oxygen is a key component of the sequential organ failure assessment score that operationally defines sepsis. But, it is calculated infrequently due to the need for the acquisition of an arterial blood gas. So, we sought to find an o...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab5154
更新日期:2019-12-03 00:00:00
abstract::The assessment and diagnosis of lower limb peripheral arterial occlusive disease (PAOD) is important since it can lead progressively to disabling claudication, ischaemic rest pain and gangrene. Historically, the first assessment has been palpation of the peripheral pulse since it can become damped, delayed and diminis...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/5/018
更新日期:2005-10-01 00:00:00
abstract::The most common method of clinical measurement of arterial blood pressure is by means of the cuff sphygmomanometer. This instrument has provided fundamental quantitative information on arterial pressure in individual subjects and in populations and facilitated estimation of cardiovascular risk related to levels of blo...
journal_title:Physiological measurement
pub_type: 历史文章,杂志文章,评审
doi:10.1088/0967-3334/31/1/R01
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:In this research, we introduce a new methodology for atrial fibrillation (AF) diagnosis during sleep in a large population sample at risk of sleep-disordered breathing. APPROACH:The approach leverages digital biomarkers and recent advances in machine learning (ML) for mass AF diagnosis from overnight-hours o...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abb8bf
更新日期:2020-11-06 00:00:00
abstract::We present an adaptive algorithm for solving the inverse problem in electrical impedance tomography. To strike a balance between the accuracy of the reconstructed images and the computational efficiency of the forward and inverse solvers, we propose to combine an adaptive mesh refinement technique with the adaptive Ka...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/6/1111
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:Video and sound acquisition and processing technologies have seen great improvements in recent decades, with many applications in the biomedical area. The aim of this paper is to review the overall state of the art of advances within these topics in paediatrics and to evaluate their potential application for ...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/1361-6579/ab0096
更新日期:2019-02-26 00:00:00