Abstract:
OBJECTIVE:In this research, we introduce a new methodology for atrial fibrillation (AF) diagnosis during sleep in a large population sample at risk of sleep-disordered breathing. APPROACH:The approach leverages digital biomarkers and recent advances in machine learning (ML) for mass AF diagnosis from overnight-hours of single-channel electrocardiogram (ECG) recording. Four databases, totaling n = 3088 patients and p = 26 913 h of continuous single-channel electrocardiogram raw data were used. Three of the databases (n = 125, p = 2513) were used for training a ML model in recognizing AF events from beat-to-beat time series. Visit 1 of the sleep heart health study database (SHHS1, n = 2963, p = 24 400) was used as the test set to evaluate the feasibility of identifying prominent AF from polysomnographic recordings. By combining AF diagnosis history and a cardiologist's visual inspection of individuals suspected of having AF (n = 118), a total of 70 patients were diagnosed with prominent AF in SHHS1. MAIN RESULTS:Model prediction on SHHS1 showed an overall [Formula: see text]and [Formula: see text] in classifying individuals with or without prominent AF. [Formula: see text] was non-inferior (p = 0.03) for individuals with an apnea-hypopnea index (AHI) ≥15 versus AHI < [Formula: see text]. Over 22% of correctly identified prominent AF rhythm cases were not previously documented as AF in SHHS1. SIGNIFICANCE:Individuals with prominent AF can be automatically diagnosed from an overnight single-channel ECG recording, with an accuracy unaffected by the presence of moderate-to-severe obstructive sleep apnea. This approach enables identifying a large proportion of AF individuals that were otherwise missed by regular care.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Chocron A,Efraim R,Mandel F,Rueschman M,Palmius N,Penzel T,Elbaz M,Behar JAdoi
10.1088/1361-6579/abb8bfsubject
Has Abstractpub_date
2020-11-06 00:00:00pages
104001issue
10eissn
0967-3334issn
1361-6579journal_volume
41pub_type
杂志文章abstract::The heart rate variability is composed of low- and high-frequency fluctuations, which are mediated by the sympathetic and the parasympathetic nervous systems. The baseline and the amplitude of the photoplethysmographic (PPG) signal also show fluctuations in the same frequencies. In the current study, PPG examinations ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/19/1/008
更新日期:1998-02-01 00:00:00
abstract::Linear methods of reconstruction play an important role in medical electrical impedance tomography (EIT) and there is a wide variety of algorithms based on several assumptions. With the Graz consensus reconstruction algorithm for EIT (GREIT), a novel linear reconstruction algorithm as well as a standardized framework ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/6/1161
更新日期:2015-06-01 00:00:00
abstract::The wrist is increasingly being used as the preferred site for objectively assessing physical activity but the relative accuracy of processing methods for wrist data has not been determined. OBJECTIVE:This study evaluates the validity of four processing methods for wrist-worn ActiGraph (AG) data against energy expend...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aa6d00
更新日期:2017-06-01 00:00:00
abstract::Dual-energy x-ray absorptiometry (DXA) is a precise, widely used method for measuring bone mineral density (BMD), usually of the lumbar spine and femoral neck. Recent developments, such as a lower x-ray tube current and pixel by pixel analysis, enable smaller bones and thinner tissues volumes, as in the hand, to be me...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/18/3/008
更新日期:1997-08-01 00:00:00
abstract::During voluntary contractions in humans, the subcutaneous tissues between surface electrodes and active motor units have been shown to attenuate surface electromyographic (EMG) signal amplitude. The purpose of this investigation was to examine the relationship between adipose tissue thickness and the electromechnical ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/37/3/418
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:Doppler ultrasound (US) is the most commonly applied method to measure the fetal heart rate (fHR). When the fetal heart is not properly located within the ultrasonic beam, fHR measurements often fail. As a consequence, clinical staff need to reposition the US transducer on the maternal abdomen, which can be a...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aa8a1a
更新日期:2017-09-21 00:00:00
abstract::Capillary refill time (CRT) is a simple means of cardiovascular assessment which is widely used in clinical care. Currently, CRT is measured through manual assessment of the time taken for skin tone to return to normal colour following blanching of the skin surface. There is evidence to suggest that manually assessed ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/1/83
更新日期:2016-01-01 00:00:00
abstract::The activPAL™ activity monitor has potential for use in youth with Cerebral Palsy (CP) as it has demonstrated acceptable validity for the assessment of sedentary and physical activity in other populations. This study determined the validity of the activPAL™ activity monitor for the measurement of sitting, standing, wa...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/11/2307
更新日期:2014-11-01 00:00:00
abstract::Hand bone equivalent phantoms (250 ml) carrying selenium in various amounts were irradiated and counted for in vivo neutron activation analysis (IVNAA) by employing a 4π NaI(TI) based detection system. During the analysis of counting data, a feature at a higher energy than the gamma ray peak from (77m)Se (0.162 MeV) w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/12/N127
更新日期:2015-12-01 00:00:00
abstract::Patients with claudication have an inadequate haemodynamic response to exercise. Blood flow response will not only have a magnitude, but also a rate of change. There is scope for investigating these parameters, as manipulation of the factors which control them may benefit work to improve the treatment for claudication...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/26/6/002
更新日期:2005-12-01 00:00:00
abstract::The left atrium (LA) plays an important role in the maintenance of hemodynamic and electrical stability of the heart. One of the conditions altering the atrial mechanical function is atrial fibrillation (AF), leading to an increased thromboembolic risk due to impaired mechanical function. Preserving the regions of the...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/5/763
更新日期:2014-05-01 00:00:00
abstract::Several factors affect the viability of biosensor design. A computer-based model is being developed to enable the sources and effect of noise and variability within the sensor to be analysed. The work now presented details the modelling of the biochemical aspect of the biosensor model-the immunoassay. The equilibrium ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/3/318
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:Atrial fibrillation (AF) causes marked risk for patients, while silent fibrillation may remain unnoticed if not suspected and screened. Development of comfortable yet accurate beat-to-beat heart rate (HR) monitoring with good AF detection sensitivity would facilitate screening and improve treatment. The purpo...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aac9a9
更新日期:2018-06-27 00:00:00
abstract::The assessment and diagnosis of lower limb peripheral arterial occlusive disease (PAOD) is important since it can lead progressively to disabling claudication, ischaemic rest pain and gangrene. Historically, the first assessment has been palpation of the peripheral pulse since it can become damped, delayed and diminis...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/5/018
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:Non-contact physiological measurement is a growing research area that allows capturing vital signs such as heart rate (HR) and breathing rate (BR) comfortably and unobtrusively with remote devices. However, most of the approaches work only in bright environments in which subtle photoplethysmographic and balli...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aae625
更新日期:2018-10-30 00:00:00
abstract::Nasal obstruction disturbs comfort during daytime, and sleep quality. Convenient objective assessment of nasal ventilation would be desirable. Therefore, we developed a technique for unobtrusive monitoring of bilateral nasal airflow. Nasal cannulae with separated left- and right-sided tubings were connected to two pre...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/1/007
更新日期:2005-02-01 00:00:00
abstract::The non-invasive measurement of free field snoring sounds to estimate the site of snoring is an important development in the diagnosis, treatment and management of sleep-related breathing disorders. We investigated characteristics of the probability density function by testing the sensitivity of the statistical moment...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/10/008
更新日期:2007-10-01 00:00:00
abstract::Urinary catheters (drainage tubes) are in widespread use. The most common type of long-term catheter is the Foley, which is made from natural or synthetic rubber. Foley catheters are passed into the bladder via the urethra or the suprapubic puncture channel (through the abdominal wall). A simulator for the abdominal w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/3/308
更新日期:2001-08-01 00:00:00
abstract::In magnetic resonance electrical impedance tomography (MREIT) we inject currents through electrodes placed on the surface of a subject and try to reconstruct cross-sectional resistivity (or conductivity) images using internal magnetic flux density as well as boundary voltage measurements. In this paper we present a st...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/24/2/367
更新日期:2003-05-01 00:00:00
abstract::A gamma fit facilitates smoothing and extrapolation of distorted tracer-dilution curves in blood flow studies. Theoretically based empirical estimators were developed as simple alternatives to direct regression approaches from simulated gamma distributions with a wide range of shape asymmetry. Key curve features of pe...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/4/401
更新日期:2001-11-01 00:00:00
abstract::This study was done to introduce new parameters derived by time frequency analysis of heart rate variability data. Four simulation experiments were carried out to compare the short-time Fourier transform (STFT) analysis method to the traditional overall spectral analysis method. Sinusoidal signals were generated with ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/21/2/303
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of maternal hyperoxygenation on fetal heart rate (FHR) when applied for suspected fetal distress during the second stage of term labor. APPROACH:A single-center randomized controlled trial was conducted in a tertiary care hospital in The Netherlands. Participants were included durin...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abc0b6
更新日期:2020-12-11 00:00:00
abstract::The aim of this study was to analyse the feasibility of long-term measurements of cerebral (crSO2) and peripheral (prSO2) regional tissue oxygen saturation on the first day of life by determining the amount of artefacts and their influence on rSO2. Near infrared spectroscopy (NIRS) measurements were performed fronto-p...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/7/1349
更新日期:2014-07-01 00:00:00
abstract::Using a primary coil that induces eddy currents in a volume conductor, and a pair of secondary coils configured to form a differential transformer, it is possible to measure the conductivity of a volume conductor by the magnetic fields of the induced eddy currents. This method is especially favourable for measuring im...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/4/007
更新日期:1993-11-01 00:00:00
abstract::Electrical impedance tomography (EIT) estimates an image of change in electrical properties within a body from stimulations and measurements at surface electrodes. There is significant interest in EIT as a tool to monitor and guide ventilation therapy in mechanically ventilated patients. In lung EIT, the EIT inverse p...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/6/1035
更新日期:2014-06-01 00:00:00
abstract::Measurement of the velocity of propagation and attenuation of ultrasound (200 kHz) is believed to be a useful non-invasive technique for assessing the mechanical properties of bone. A new method for the determination of ultrasound velocity and attenuation of longitudinal waves in cortical bone was used in vivo and in ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/17/3/006
更新日期:1996-08-01 00:00:00
abstract::The purpose of this study was to examine the validity and reliability of estimated parameters of the work-time relationship during cross-country ski ergometry using the traditional multi-trial critical power (CP) test and a 3 min 'all-out' test (3MT). Fourteen recreationally active male participants (mean ± SD; age: 2...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/1/31
更新日期:2014-01-01 00:00:00
abstract::In this paper we present the T-SCAN technology and its use as a diagnostic tool for breast cancer detection. We show, using theoretical models with simplified geometries, that displaying planar two-dimensional maps of the currents detected at the breast's surface relate to the electric field distribution within the br...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/1/301
更新日期:2001-02-01 00:00:00
abstract::The paper describes the development of an electrical impedance tomography (EIT) system for gynecologic research. The GIT (gynecological impedance tomography) system has 48 electrodes and is embedded on a small space (30 mm diameter and 20 mm height) inside of the vaginal probe. The system provides real-time (one shot ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/33/5/849
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Using raw, sub-second-level accelerometry data, we propose and validate a method for identifying and characterizing walking in the free-living environment. We focus on sustained harmonic walking (SHW), which we define as walking for at least 10 s with low variability of step frequency. APPROACH:We utilize th...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaa74d
更新日期:2018-02-28 00:00:00