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Tumor necrosis factor-alpha gene is expressed in stimulated retinal pigment epithelial cells in culture.

Abstract：

:Expression of TNF-alpha gene in the retinal pigment epithelial (RPE) cells was studied by using polymerase chain reaction (PCR). PCR for human TNF-alpha gene using complementary DNA (cDNA) of control RNA prepared from non-stimulated RPE cells failed to show expression of TNF-alpha gene. However, PCR by using cDNA prepared from interleukin-1 beta (IL-1 beta)-stimulated RPE cells revealed expression of the gene, suggesting in vivo production of TNF-alpha from RPE cells in response to IL-1 beta.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Tanihara H,Yoshida M,Yoshimura N

doi

10.1016/0006-291x(92)91300-f

subject

Has Abstract

pub_date

1992-09-16 00:00:00

pages

1029-34

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(92)91300-F

journal_volume

187

pub_type

杂志文章

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