Lateral visual field stimulation reveals extrastriate cortical activation in the contralateral hemisphere: an fMRI study.

Abstract:

:We examined whether lateral visual field stimulation (LSTM) could activate contralateral extrastriate cortical areas as predicted by a large experimental literature. We asked seven unscreened, control subjects to wear glasses designed to allow vision out of either the left (LVF) or right lateral visual field (RVF) depending upon which side the subject looked toward. Each subject participated in a block design functional magnetic resonance imaging (fMRI) study with alternating 30-s epochs in which he was asked to look to one side and then the other for a total of five epochs. On each side of the bore of the scanner, we taped a photograph for the subject to view in the LVF and RVF. The data were analyzed with SPM99 using a fixed effect, box-car design with contrasts for the LVF and the RVF conditions. Both LVF and RVF conditions produced the strongest fMRI activation in the contralateral occipitotemporal and posterior parietal areas as well as the contralateral dorsolateral prefrontal cortex. LSTM appears to increase contralateral fMRI activation in striate and extrastriate cortical areas as predicted by earlier studies reporting differential cognitive and/or emotional effects from unilateral sensory or motor stimulation.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Schiffer F,Mottaghy FM,Pandey Vimal RL,Renshaw PF,Cowan R,Pascual-Leone A,Teicher M,Valente E,Rohan M

doi

10.1016/j.pscychresns.2004.01.002

subject

Has Abstract

pub_date

2004-05-30 00:00:00

pages

1-9

issue

1

eissn

0165-1781

issn

1872-7123

pii

S0925492704000198

journal_volume

131

pub_type

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