Abstract：
:Few reports on population-based studies of birth rate among epilepsy patients have been published. In most previous studies, fertility has been lower among epilepsy patients than in the rest of the population. However, conflicting results have also been reported. Because of small samples and selective material, the generalizability of these results is also limited. The authors conducted a population-based cohort study of birth rate (1985-2001) in a nationwide Finnish cohort of patients with newly diagnosed epilepsy and a population-based reference cohort. All patients (n = 14,077) approved as eligible for reimbursement for antiepileptic medication from the Social Insurance Institution of Finland (KELA) for the first time between 1985 and 1994 were identified from the KELA database. A reference cohort (n = 29,828) was identified from the Finnish Population Register Center, with frequency-matching on age. Information on follow-up status and livebirths were also obtained from the Finnish Population Register Center. The birth rate was lower in patients with epilepsy than in the reference cohort among both men (hazard ratio = 0.58, 95% confidence interval: 0.54, 0.62) and women (hazard ratio = 0.88, 95% confidence interval: 0.83, 0.93). There were a clear decreasing trend by age at observation in men with epilepsy and a moderate decreasing trend by age at start of follow-up in women with epilepsy.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Artama M,Isojärvi JI,Raitanen J,Auvinen Adoi
10.1093/aje/kwh140subject
Has Abstractpub_date
2004-06-01 00:00:00pages
1057-63issue
11eissn
0002-9262issn
1476-6256pii
159/11/1057journal_volume
159pub_type
杂志文章abstract：:The fasting plasma glucose (FPG) was measured in 4170 nondiabetic adult residents of a suburban California community. At all ages the median FPG in men was higher (103-107 mg/dl) than the median FPG in women (96-104 mg/dl). FPG levels correlated weakly with obesity, and male-female differences persisted after adjustme...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113021
更新日期：1980-10-01 00:00:00
abstract：:The authors modeled the possible consequences for US cataract incidence of increases in ultraviolet B radiation due to ozone depletion. Data on the dose-response relation between ocular exposure to ultraviolet B radiation and cortical cataract were derived from a population-based study (the Salisbury Eye Evaluation Pr...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwi329
更新日期：2005-12-01 00:00:00
abstract：:This study involved direct observation of the differences in utilization of medical care by smokers, nonsmokers, and former smokers. A household interview survey conducted in 1970-1971 obtained detailed information about the smoking patterns of 2,582 adult members of the Northwest Kaiser Permanente health maintenance ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114187
更新日期：1985-12-01 00:00:00
abstract：:A total of 1,054 Hong Kong Chinese subjects aged 70 years or over were recruited into a cohort study to investigate the relation between social support and health outcomes. More than 30 social, health, and behavioral characteristics were recorded as baseline information when the study began in 1985. Mortality data wer...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115970
更新日期：1991-05-01 00:00:00
abstract：:In the mid-19th century, the German hygienist Max von Pettenkofer viewed cholera as resulting from the interaction between a postulated cholera germ and the characteristics of soils. In order to cause cholera, the cholera germ had to become a cholera miasma, but this transformation required prolonged contact of the ge...
journal_title：American journal of epidemiology
pub_type： 传,历史文章,杂志文章
doi：10.1093/aje/kwm279
更新日期：2007-12-01 00:00:00
abstract：:The authors evaluated the progression of human immunodeficiency virus type 1 (HIV-1) disease from the date of seroconversion to the development of acquired immunodeficiency syndrome (AIDS) and death among 362 well-documented seroconverters. The participants were homosexual men in hepatitis B vaccine trials in Amsterda...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116951
更新日期：1994-06-01 00:00:00
abstract：:Alcohol drinking has been extensively studied in relation to prostate cancer, yet findings on the direction of the association are equivocal. Previous studies have not examined drinking patterns. Thus, the authors prospectively evaluated the associations between these factors and risk of incident prostate cancer (n = ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh062
更新日期：2004-03-01 00:00:00
abstract：:In this paper, the authors present an objective system to evaluate interviewer performance for use in epidemiologic studies. With this quality control system, all study interviews are audio-taped, and a random sample of interviews are coded according to interviewer behaviors, such as whether the interviewer asked the ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117192
更新日期：1994-12-01 00:00:00
abstract：:The analysis of exposure misclassification has received considerable attention in the epidemiologic literature, with the result that methods for correcting many summary risk estimates for such misclassification are well known. However, the application of such methods typically requires more data than are usually publi...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117653
更新日期：1995-08-15 00:00:00
abstract：:Planners of several large prevention trials have overestimated the expected incidence of events in the control group, largely because they failed either to recognize or to adequately correct for various effects of population selection. Consequently, the studies have been too small in size or too short in duration to a...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116739
更新日期：1993-04-01 00:00:00
abstract：:Two six-month randomized, controlled double-blind trials of the efficacy of virucidal nasal tissues in the prevention of natural colds were conducted in Charlottesville, Virginia, between 1983 and 1986. Tissues impregnated with malic and citric acids and sodium lauryl sulfate were used in both trials. Placebo tissues ...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/oxfordjournals.aje.a115059
更新日期：1988-11-01 00:00:00
abstract：:The authors used a transgenerational data set of Illinois vital records to ascertain the relation between parental birth weights and infant birth weight. The infant generation consisted of all African Americans and whites born in Illinois during 1989-1991. The parent generation included the mothers and fathers who wer...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009197
更新日期：1997-11-15 00:00:00
abstract：:The authors examined the association between the use of diethylstilbestrol during pregnancy and the risk of subsequent fatal breast cancer in a large prospective study of US adults. After 9 years of follow-up, 1,574 cases of fatal breast cancer were observed among 501,536 gravid women who reported no prior history of ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008976
更新日期：1996-10-01 00:00:00
abstract：:In a population-based case-control study of the association between use of diuretics and renal cell cancer, 120 white men whose cancer was diagnosed during the years 1980-1991 and 86 white women diagnosed in 1960-1991 were identified among members of the Kaiser Permanente Northwest health plan. Controls were plan memb...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117328
更新日期：1994-11-01 00:00:00
abstract：:After diagnosis with prostate cancer, Black men in the United States have poorer survival than White men, even after controlling for differences in cancer stage. The extent to which these racial survival differences are due to biologic versus non-biologic factors is unclear, and it has been hypothesized that differenc...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a010221
更新日期：2000-02-15 00:00:00
abstract：:In randomized controlled trials, the intention-to-treat estimator provides an unbiased estimate of the causal effect of treatment assignment on the outcome. However, patients often want to know what the effect would be if they were to take the treatment as prescribed (the patient-oriented effect), and several research...
journal_title：American journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1093/aje/kwv065
更新日期：2015-09-15 00:00:00
abstract：:The objective was to study changes in the occurrence of human immunodeficiency virus type 1-related Kaposi's sarcoma and the association with degree of immunodeficiency over time. Danish patients with acquired immunodeficiency syndrome (AIDS) diagnosed between 1979 and 1990 (n = 687) were followed clinically and with ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117481
更新日期：1995-04-01 00:00:00
abstract：:A randomized field trial was conducted in Tecumseh, Michigan, to test the efficacy of virucidal nasal tissues in interrupting transmission of respiratory agents in the household. In the double-blinded trial, 296 households were stratified by household size and randomly assigned to the group using treated tissues and t...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/oxfordjournals.aje.a115011
更新日期：1988-09-01 00:00:00
abstract：:Although erectile dysfunction is frequently seen in patients with manifestations of arteriosclerotic disease, the independent contribution of serum cholesterol in predicting erectile dysfunction is unclear. The aim of this study was to examine the relation between serum cholesterol and erectile dysfunction. Medical hi...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117181
更新日期：1994-11-15 00:00:00
abstract：:Differential survival associated with insulin-dependent diabetes mellitus (IDDM) was evaluated in a cross-country study using four population-based IDDM cohorts from Japan (n = 1,374), Israel (n = 610), Allegheny County, Pennsylvania (n = 995), and Finland (n = 5,144). For the purpose of this cross-country comparison,...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：
更新日期：1995-09-15 00:00:00
abstract：:Inflammatory bowel disease refers to a group of chronic diseases of unknown etiology related to both genetic and environmental factors. In this 1990-1993 study, the authors investigated associations between the content and quality of drinking water and the incidence of inflammatory bowel disease. They used data from a...
journal_title：American journal of epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1093/aje/kwn218
更新日期：2008-11-01 00:00:00
abstract：:The relation between use of conjugated estrogens and the risk of uterine cancer was examined among 188 white women with newly diagnosed endometrial cancer and 428 controls hospitalized for nonmalignant conditions requiring surgery at the Boston Hospital for Women-Parkway Division, Boston, Massachusetts, in January 197...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114414
更新日期：1986-09-01 00:00:00
abstract：:Several studies suggest that toxic chemicals in hair products may be absorbed through the scalp in sufficient amounts to increase the risks of adverse health effects in women or their infants. This case-control study of 525 Black women from three counties in North Carolina who had delivered a singleton, liveborn infan...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009879
更新日期：1999-04-15 00:00:00
abstract：:Although effective in controlling malaria, indoor residual spraying results in elevated exposure to insecticides such as dichlorodiphenyltrichloroethane (DDT) and pyrethroids. These chemicals cross the placenta, but no studies have examined their associations with birth outcomes in populations residing in indoor resid...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwy143
更新日期：2019-01-01 00:00:00
abstract：:The role of influenzalike illnesses and influenza vaccination in the development of Guillain-Barré syndrome (GBS), particularly the role of A/H1N1 epidemics and A/H1N1 vaccination, is debated. Data on all incident GBS cases meeting the Brighton Collaboration criteria that were diagnosed at 25 neurology centers in Fran...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwr072
更新日期：2011-08-01 00:00:00
abstract：:Diabetes mellitus is a heterogeneous disease. The better classification of types of diabetes mellitus among adults will improve epidemiologic studies of determinants of risk factors and genetic host susceptibility. Recently, an antibody to a specific enzyme, glutamic acid decarboxylase, has been closely linked to insu...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117316
更新日期：1994-10-15 00:00:00
abstract：:A recent trial showed that universal decolonization in adult intensive care units (ICUs) resulted in greater reductions in all bloodstream infections and clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) than either targeted decolonization or screening and isolation. Since regional health-care fa...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kww008
更新日期：2016-03-01 00:00:00
abstract：:To understand whether neighborhood contexts contribute to the onset or maintenance of mental health problems independently of individual characteristics requires the use of multilevel study designs and analytical strategies. This study used a multilevel analytical framework to examine the relation between neighborhood...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwi185
更新日期：2005-08-01 00:00:00
abstract：:The association between standardized cancer mortality rate ratios from 1969-1978 and dietary practices was examined in an ecologic study of the 24 counties of Sweden by means of several independent data sources. The study supports the hypothesis that a high intake of cereal fiber protects against colorectal cancer (r ...
journal_title：American journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1093/oxfordjournals.aje.a114789
更新日期：1988-01-01 00:00:00
abstract：:Agreement between maternal interview- and medical record-based gestational age was assessed by using data from a case-control study of childhood strabismus. The sample consisted of 383 cases of strabismus and their age-matched controls, diagnosed between 1985 and 1986 in Baltimore, Maryland, who were under age 7 years...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116534
更新日期：1992-09-01 00:00:00
