Abstract:
:Although effective in controlling malaria, indoor residual spraying results in elevated exposure to insecticides such as dichlorodiphenyltrichloroethane (DDT) and pyrethroids. These chemicals cross the placenta, but no studies have examined their associations with birth outcomes in populations residing in indoor residual spraying areas. We investigated this question in the Venda Health Examination of Mothers, Babies and Their Environment (VHEMBE), a birth cohort study of 751 South African children born between 2012 and 2013. We measured maternal peripartum serum DDT and urine pyrethroid metabolite concentrations and collected data on birth weight, length, head circumference, and duration of gestation. We analyzed the data using marginal structural models with inverse-probability-of-treatment weights, generalized propensity scores, and standard conditional linear regression. Using all 3 analytical methods, p,p'-DDT, o,p'-DDT, and to a lesser extent p,p'-dichlorodiphenyldichloroethylene were related to elevated birth weight, birth length, and head circumference among girls. Changes in gestational duration did not mediate this relationship, suggesting that these exposures accelerate fetal growth, which is consistent with the known estrogenic properties of o,p'-DDT and p,p'-DDT. No associations with pyrethroid metabolites were found. Results suggest that prenatal exposure to DDT is related to elevated birth size. Further studies are needed to elucidate the implications of these findings.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Chevrier J,Rauch S,Crause M,Obida M,Gaspar F,Bornman R,Eskenazi Bdoi
10.1093/aje/kwy143subject
Has Abstractpub_date
2019-01-01 00:00:00pages
130-140issue
1eissn
0002-9262issn
1476-6256pii
5050979journal_volume
188pub_type
杂志文章abstract::Many smokers believe that electronic nicotine delivery systems (ENDS) and pharmaceutical cessation aids can help them quit smoking or reduce cigarette consumption, but the evidence for e-cigarettes to aid quitting is limited. Examining 3,093 quit attempters in the nationally representative US Population Assessment of ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwy129
更新日期:2018-11-01 00:00:00
abstract::A new measure of lifetime alcohol consumption, the Cognitive Lifetime Drinking History (CLDH) uses beverage-specific questions on drink sizes and assesses drinking patterns to enhance recall. Two methods of establishing drinking intervals were examined: 1) floating--the respondent's report of when drinking changed, an...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009225
更新日期:1997-12-01 00:00:00
abstract::The identity of the etiologic agent that caused the 1981 epidemic of toxic oil syndrome in Spain has not been established, and toxicologic study of oil specimens from the outbreak has been hampered by uncertainty about which oils were actually capable of causing illness. To identify chemical characteristics associated...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114914
更新日期:1988-06-01 00:00:00
abstract::A community sample made in the fall of 1972 in Durham County, North Carolina, and that consisted of 331 persons 65 years of age and older was assessed for adequacy of social support along three parameters: roles and available attachments, perceived social support, and frequency of social interaction. This approach to ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113351
更新日期:1982-05-01 00:00:00
abstract::Coronary heart disease is the leading cause of mortality among persons with diabetes mellitus, but the factors that account for this high coronary heart disease mortality remain unclear. In the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study, conducted from 1982 to 1984, 92 deaths from...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115834
更新日期:1991-06-15 00:00:00
abstract::When researching racial disparities in health, residential segregation cannot be ignored. Because of segregation, contextual differences by race are so pronounced that ignoring them may lead to mis-estimating the effect of individual-level factors. However, given the stark racial separation of social contexts, researc...
journal_title:American journal of epidemiology
pub_type: 评论,杂志文章
doi:10.1093/aje/kwn290
更新日期:2008-12-01 00:00:00
abstract::To examine whether intakes of wine, beer, spirits, and total alcohol are associated with the risk of common cold, in 1998-1999 the authors analyzed data from a cohort study carried out in a population of 4,272 faculty and staff of five Spanish universities. Usual alcohol intake was assessed at baseline by means of a s...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/155.9.853
更新日期:2002-05-01 00:00:00
abstract::To understand whether neighborhood contexts contribute to the onset or maintenance of mental health problems independently of individual characteristics requires the use of multilevel study designs and analytical strategies. This study used a multilevel analytical framework to examine the relation between neighborhood...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwi185
更新日期:2005-08-01 00:00:00
abstract::It is common in population screening surveys or in the investigation of new diagnostic tests to have results from one or more tests investigating the same condition or disease, none of which can be considered a gold standard. For example, two methods often used in population-based surveys for estimating the prevalence...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a117428
更新日期:1995-02-01 00:00:00
abstract::There is broad agreement that religion is a social determinant of health. In the article by Chen and VanderWeele (Am J Epidemiol. 2018;187(11):2355-2364), the authors took an outcome-wide approach to demonstrate associations between religious practices early in the life course (regular service attendance and prayer/me...
journal_title:American journal of epidemiology
pub_type: 评论,杂志文章
doi:10.1093/aje/kwz204
更新日期:2020-12-01 00:00:00
abstract::More than a century of empirical evidence links marital status to mortality. However, the hazards of dying associated with long-term marital trajectories and contributing risk factors are largely unknown. The authors used 1992-2006 prospective data from a cohort of US adults to investigate the impact of current marita...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwp194
更新日期:2009-09-01 00:00:00
abstract::This report describes the development of hypertension among 1,270 males (aged 23-80 years at the time of entry into the study) observed prospectively for 10 years who had a baseline blood pressure of less than 140/90 mmHg and who underwent baseline spirometry. Subjects were participants in the Normative Aging Study, a...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114854
更新日期:1988-04-01 00:00:00
abstract::To assess whether recent coffee consumption is related to the incidence of large bowel cancer, the authors analyzed data from a multipurpose hospital-based case-control study of several cancers, conducted from 1978 to 1986 in Boston, Massachusetts, New York, New York, Philadelphia, Pennsylvania, and Baltimore, Marylan...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115422
更新日期:1989-11-01 00:00:00
abstract::The author evaluated the validity of four historically based variables collected on Georgia birth certificates: outcome of preceding pregnancy, history of delivery of a low- (<2,500 g) or high- (>4,000 g) birth-weight infant, and death of the baby resulting from the preceding pregnancy. Data were derived from birth an...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/154.10.883
更新日期:2001-11-15 00:00:00
abstract::The authors conducted descriptive and case-control studies to find factors associated with earthquake deaths due to the Great Hanshin-Awaji earthquake on January 17, 1995, in Nishinomiya, Japan. In the case-control study, cases included all 1,104 deaths. Controls were randomly selected from survivors. Earthquake morta...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/153.2.153
更新日期:2001-01-15 00:00:00
abstract::Maternal concentrations of insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein 1 (IGFBP-1) may influence fetal growth. Offspring birth weight related to maternal IGF-I and IGFBP-1 measured in pregnancy was studied in 368 randomly selected women without preeclampsia who delivered a singl...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwr067
更新日期:2011-07-15 00:00:00
abstract::Using 1973-2000 mesothelioma incidence data released by the Surveillance, Epidemiology, and End Results Program in April 2003, the authors estimated the parameters of a birth-cohort and age model to determine whether previously reported patterns of mesothelioma in the United States have changed. Compared with analyses...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwh025
更新日期:2004-01-15 00:00:00
abstract::Trends in sexual behavior associated with incident infection with human immunodeficiency virus (HIV) type 1 are described and a case-control study was conducted to examine risk factors for HIV seroconversion in homosexual men who became infected with HIV between 1982 and 1994 from four geographic sites: Amsterdam, the...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009311
更新日期:1997-10-01 00:00:00
abstract::We used full-system-estimation instrumental-variables simultaneous equations modeling (IV-SEM) to examine physical activity relative to body mass index (BMI; weight (kg)/height (m)(2)) using 25 years of data (1985/1986 to 2010/2011) from the Coronary Artery Risk Development in Young Adults (CARDIA) Study (n = 5,115; a...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kww010
更新日期:2016-09-15 00:00:00
abstract::The purpose of this study was to assess the effect of weight in middle-aged men and subsequent weight change on the risk of osteoporosis three decades later. The authors utilized data from 1,476 Norwegian men participating in two health screenings in Oslo (1972-1973 and 2000-2001) and Tromsø (1974-1975 and 2001). Heig...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwn151
更新日期:2008-08-15 00:00:00
abstract::Since a positive association between blood pressure and plasma glucose level in child populations has been observed previously, we studied this relationship in a stratified random sample of children ages 7-15 years drawn from a total geographic population. We stratified this population (N = 3524) by diastolic blood pr...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113103
更新日期:1981-04-01 00:00:00
abstract::Preliminary evidence suggests that daytime sleepiness may predate clinical diagnosis of Parkinson disease. The authors examined daytime napping and nighttime sleeping durations, reported in 1996-1997 by 220,934 US NIH-AARP Diet and Health Study participants, in relation to Parkinson disease diagnoses at 3 clinical sta...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq478
更新日期:2011-05-01 00:00:00
abstract::The association between a single interpregnancy interval (IPI) and birth outcomes has not yet been explored using matched methods. We modeled the odds of preterm birth, being small for gestational age, and having low birth weight in a second, live-born infant in a cohort of 192,041 sibling pairs born in Western Austra...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwy188
更新日期:2019-01-01 00:00:00
abstract::The absence of any standard definition of suicide cluster events hinders understanding of the prevalence of the problem, hinders the development of appropriate public health responses to observed clusters, and ultimately hinders investigation of the mechanisms underlying contagious communication of suicidal behavior. ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115781
更新日期:1990-07-01 00:00:00
abstract::Diagnostic testing is recommended in women with "ovarian cancer symptoms." However, these symptoms are nonspecific. The ongoing Diagnosing Ovarian Cancer Early (DOVE) Study in Montreal, Quebec, Canada, provides diagnostic testing to women aged 50 years or older with symptoms lasting for more than 2 weeks and less than...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kww086
更新日期:2016-11-01 00:00:00
abstract::A statewide cross-sectional study of risk factors for seropositivity for antibody to Borrelia burgdorferi in outdoor workers in New Jersey was performed in September and October 1988. The crude odds ratio associated with exposure to ticks on the primary state job was 2.2 (95% confidence interval (CI) 0.7-9.0). After a...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115578
更新日期:1990-05-01 00:00:00
abstract::Stroke mortality is reported to be greater in blacks than in whites, but stroke incidence data for blacks and Hispanics are sparse. The aim of this study was to determine and compare stroke incidence rates among whites, blacks, and Hispanics living in the same urban community. A population-based incidence study was co...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009445
更新日期:1998-02-01 00:00:00
abstract::The aim of this study was to reconcile 3 approaches to calculating population attributable fractions and attributable burden percentage: the approach of Bruzzi et al. (Am J Epidemiol. 1985;122(5):904-914.), the maximum-likelihood method of Greenland and Drescher (Biometrics. 1993;49(3):865-872.), and the multivariable...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwx200
更新日期:2018-01-01 00:00:00
abstract::Despite interest in the built food environment, little is known about the validity of commonly used secondary data. The authors conducted a comprehensive field census identifying the locations of all food outlets using a handheld global positioning system in 8 counties in South Carolina (2008-2009). Secondary data wer...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq292
更新日期:2010-12-01 00:00:00
abstract::A standardized method for examining hearts and coronary arteries was applied in a study of sudden deaths in 227 autopsies of New Orleans men aged 25-49 years. Of these autopsies, 102 deaths were due to external violence, 125 were from natural causes and 45 occurred suddenly. Of the sudden natural deaths, 14 (31%) were...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113036
更新日期:1980-11-01 00:00:00