Changing patterns of Kaposi's sarcoma in Danish acquired immunodeficiency syndrome patients with complete follow-up. The Danish Study Group for HIV Infection (DASHI).

Abstract:

:The objective was to study changes in the occurrence of human immunodeficiency virus type 1-related Kaposi's sarcoma and the association with degree of immunodeficiency over time. Danish patients with acquired immunodeficiency syndrome (AIDS) diagnosed between 1979 and 1990 (n = 687) were followed clinically and with consecutive CD4 cell count measurement from time of AIDS-defining illness to date of death or censoring date, whichever came first. The proportion of homo-/bisexual men (n = 520) with Kaposi's sarcoma (n = 100) at AIDS diagnosis declined from 31% before 1985 to 13% in 1990, whereas the proportion of patients who died with Kaposi's sarcoma remained constant over time. Furthermore, the CD4 cell count at time of AIDS for patients diagnosed with Kaposi's sarcoma has declined in recent years. A CD4 cell count < 200 x 106/liter at the time of AIDS diagnosis predicted an increased risk of developing Kaposi's sarcoma after the AIDS diagnosis. Age, antiretroviral therapy, and primary Pneumocystis carinii pneumonia prophylaxis failed to influence the development of Kaposi's sarcoma. Thus, the occurrence of Kaposi's sarcoma remained constant over time but developed later in the course of AIDS and was associated with more severe immunosuppression in recent years.

journal_name

Am J Epidemiol

authors

Lundgren JD,Melbye M,Pedersen C,Rosenberg PS,Gerstoft J

doi

10.1093/oxfordjournals.aje.a117481

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

652-8

issue

7

eissn

0002-9262

issn

1476-6256

journal_volume

141

pub_type

杂志文章
  • Longitudinal analysis of changes in indices of obesity from age 8 years to age 18 years. Project HeartBeat!

    abstract::To compare growth patterns of obesity indices derived from body composition and anthropometric measures, the authors analyzed data from Project HeartBeat!, a longitudinal study of cardiovascular disease risk factors in childhood and adolescence. A total of 678 children initially aged 8, 11, and 14 years in The Woodlan...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwf109

    authors: Dai S,Labarthe DR,Grunbaum JA,Harrist RB,Mueller WH

    更新日期:2002-10-15 00:00:00

  • Does arsenic exposure increase the risk for circulatory disease?

    abstract::Studies of residents in communities with high endemic concentrations of arsenic in drinking water suggest a deleterious effect on the circulatory system; however, studies among workers with high occupational exposures generally have shown either no or weak associations. This discrepancy could be a result of the health...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a010185

    authors: Hertz-Picciotto I,Arrighi HM,Hu SW

    更新日期:2000-01-15 00:00:00

  • Invited Commentary: Women's Reproductive Life Spans and Subsequent Inflammatory Profiles-How to Best Measure Reproductive Life Span and the Need for Baseline Assessments.

    abstract::Inflammatory processes are known to drive the pathogenesis of several chronic diseases, including cardiovascular disease and Alzheimer disease, as well as all-cause mortality. Emerging research indicates that women who have a longer reproductive life span-roughly determined as the period from menarche to menopause or ...

    journal_title:American journal of epidemiology

    pub_type: 评论,杂志文章

    doi:10.1093/aje/kwz266

    authors: Schliep KC

    更新日期:2020-07-01 00:00:00

  • The roles of insulin, obesity, and fat distribution in the elevation of cardiovascular risk factors in impaired glucose tolerance. The San Luis Valley Diabetes Study.

    abstract::The objective of this study was to determine whether a less favorable risk factor pattern for cardiovascular disease among persons with impaired glucose tolerance could be explained by fasting insulin, obesity, and/or a central distribution of body fat. Between 1984 and 1988, cardiovascular risk factors were examined ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116575

    authors: Burchfiel CM,Shetterly SM,Baxter J,Hamman RF

    更新日期:1992-11-01 00:00:00

  • Optimizing buccal cell DNA yields in mothers and infants for human leukocyte antigen genotyping.

    abstract::Buccal cells provide a convenient source of DNA for epidemiologic studies. Mouthwash rinses yield a higher quality and quantity of DNA than cytobrushes but are not practical for collection from infants. Although cytobrushes yield sufficient DNA for most genotyping analyses, human leukocyte antigen (HLA) analysis can r...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh171

    authors: Saftlas AF,Waldschmidt M,Logsden-Sackett N,Triche E,Field E

    更新日期:2004-07-01 00:00:00

  • Long-term effects of reproductive-age menstrual cycle patterns on peri- and postmenopausal fracture risk.

    abstract::The authors examined the association between age at menarche, menstrual cycle characteristics between ages 28 and 32 years, and peri- and postmenopausal fracture risk in a cohort of 874 women who prospectively recorded menstrual cycle data for at least 5 years from their early 20s through their menopause. Fracture his...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009173

    authors: Cooper GS,Sandler DP

    更新日期:1997-05-01 00:00:00

  • Healthy Aging 5 Years After a Period of Daily Supplementation With Antioxidant Nutrients: A Post Hoc Analysis of the French Randomized Trial SU.VI.MAX.

    abstract::This study's objective was to investigate healthy aging in older French adults 5 years after a period of daily nutritional-dose supplementation with antioxidant nutrients. The study was based on the double-blind, randomized trial, Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) Study (1994-2002) and...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwv105

    authors: Assmann KE,Andreeva VA,Jeandel C,Hercberg S,Galan P,Kesse-Guyot E

    更新日期:2015-10-15 00:00:00

  • Nine-year changes in cardiovascular disease risk factors with weight maintenance in the atherosclerosis risk in communities cohort.

    abstract::Few studies have focused on the impact of weight maintenance on cardiovascular disease risk factors or addressed whether changes differ by baseline weight status and medication usage. The authors examined these issues using 9 years of follow-up data on 3,235 men and women from the Atherosclerosis Risk in Communities (...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwk072

    authors: Truesdale KP,Stevens J,Cai J

    更新日期:2007-04-15 00:00:00

  • Aspirin use and cognitive function in the elderly.

    abstract::Decline in cognitive function in the elderly is common and represents a major clinical and public health concern. Aspirin may reduce the decline in cognitive function by influencing multi-infarct dementia, but data are sparse. The East Boston Senior Health Project is a population-based cohort study that enrolled 3,809...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008801

    authors: Stürmer T,Glynn RJ,Field TS,Taylor JO,Hennekens CH

    更新日期:1996-04-01 00:00:00

  • Poland and US collaborative study on cardiovascular epidemiology. II. Correlates of lipids and lipoproteins in men and women aged 35-64 years from selected Polish rural, Polish urban, and US samples.

    abstract::Three diverse samples of men and women aged 35-64 years living in urban Poland, rural Poland, and the United States, are described and subsequently analyzed by multiple regression methods. Total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, and the natural logarith...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115358

    authors: Sznajd J,Rywik S,Furberg B,Pajak A,Kurjata P,Williams OD,Sznajderman-Ciswicka M,Misiowiec P,Irving SH,Baczynska E

    更新日期:1989-09-01 00:00:00

  • Long term mortality and morbidity related to degree of damage following the 1998 earthquake in Armenia.

    abstract::To assess the relation of increased mortality and morbidity to personal loss and damage following the 1988 earthquake in Armenia, the authors conducted a prospective study of mortality and a nested case-control analysis of incident morbidity. Employees of the Armenian Ministry of Health and their immediate families (n...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009585

    authors: Armenian HK,Melkonian AK,Hovanesian AP

    更新日期:1998-12-01 00:00:00

  • Is there a clear threshold for fasting plasma glucose that differentiates between those with and without neuropathy and chronic kidney disease?: the Singapore Prospective Study Program.

    abstract::Recent studies suggest that no distinct glycemic threshold consistently differentiates individuals with or without retinopathy. The authors sought to determine whether the same was true for other microvascular complications. They studied 5,094 participants with fasting plasma glucose values and concurrent microvascula...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwp076

    authors: Nang EE,Khoo CM,Tai ES,Lim SC,Tavintharan S,Wong TY,Heng D,Lee J

    更新日期:2009-06-15 00:00:00

  • Exposure opportunity in case-control studies.

    abstract::Efficient control of confounding is well recognized as a legitimate motive for restriction, matching, and conditional analysis in case-control studies. Some investigators, however, have advocated use of the same techniques for another purpose: to achieve a balance of "opportunity" or "potential" for past exposure betw...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114244

    authors: Poole C

    更新日期:1986-02-01 00:00:00

  • "First-wave" bias when conducting active safety monitoring of newly marketed medications with outcome-indexed self-controlled designs.

    abstract::Large health care databases are used extensively for pharmacoepidemiologic studies. Unique methodological issues arise when applying self-controlled designs (i.e., using within-person comparisons) for active surveillance of newly marketed drugs. We use 3 examples to illustrate bias related to population-level exposure...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwu162

    authors: Wang SV,Schneeweiss S,Maclure M,Gagne JJ

    更新日期:2014-09-15 00:00:00

  • Prostatic cancer: mortality and incidence rates by race and social class.

    abstract::Among the most striking epidemiologic characteristics of prostatic cancer in the United States is the sizeable excess in rates for the disease among blacks as compared with whites. This study attempted to determine whether the higher black rates might be explained by controlling for social class, using mortality data ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112546

    authors: Ernster VL,Selvin S,Sacks ST,Austin DF,Brown SM,Winkelstein W Jr

    更新日期:1978-04-01 00:00:00

  • Clinical usefulness of the Framingham cardiovascular risk profile beyond its statistical performance: the Tehran Lipid and Glucose Study.

    abstract::The utility of a risk function in clinical practice is an important concept that has received insufficient attention. The authors evaluated the clinical usefulness of the Framingham risk function (FRF) for cardiovascular disease in a Middle Eastern population (2,640 men and 3,584 women aged 30-74 years) free of cardio...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws204

    authors: Khalili D,Hadaegh F,Soori H,Steyerberg EW,Bozorgmanesh M,Azizi F

    更新日期:2012-08-01 00:00:00

  • Air pollution and respiratory morbidity among adults in southern California.

    abstract::This paper reports the results of an investigation of the acute effects of air pollution in 321 nonsmoking adults residing in Southern California. Previous epidemiologic investigations of effects of acute exposure to ozone have focused on groups who may not be representative of the general public, such as asthmatics o...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116729

    authors: Ostro BD,Lipsett MJ,Mann JK,Krupnick A,Harrington W

    更新日期:1993-04-01 00:00:00

  • Examining overweight and obesity as risk factors for common mental disorders using fat mass and obesity-associated (FTO) genotype-instrumented analysis: The Whitehall II Study, 1985-2004.

    abstract::The Mendelian randomization approach exploits genetic variants to improve causal inference when using observational data. The authors examined the relation between long-term obesity and common mental disorders (CMD) by utilizing the known relation between fat mass and obesity-associated (FTO) genotype and body mass in...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwq444

    authors: Kivimäki M,Jokela M,Hamer M,Geddes J,Ebmeier K,Kumari M,Singh-Manoux A,Hingorani A,Batty GD

    更新日期:2011-02-15 00:00:00

  • Association of transposition of the great arteries in infants with maternal exposures to herbicides and rodenticides.

    abstract::The Baltimore-Washington Infant Study, a case-control study of congenital heart defects in liveborn infants conducted in 1981--1989, interviewed parents about a wide range of environmental exposures that occurred during and before the pregnancy. In the period 1987--1989, the questionnaire was expanded to include a det...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.6.529

    authors: Loffredo CA,Silbergeld EK,Ferencz C,Zhang J

    更新日期:2001-03-15 00:00:00

  • Blood Pressure and Arterial Stiffness in Kenyan Adolescents With the Sickle Cell Trait.

    abstract::The potential association between sickle cell trait (SCT) and increased arterial stiffness/blood pressure (BP) has not been evaluated in detail despite its association with stroke, sudden death, and renal disease. We performed 24-hour ambulatory BP monitoring and arterial stiffness measurements in adolescents raised i...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx232

    authors: Etyang AO,Wandabwa CK,Kapesa S,Muthumbi E,Odipo E,Wamukoya M,Ngomi N,Haregu T,Kyobutungi C,Williams TN,Makale J,Macharia A,Cruickshank JK,Smeeth L,Scott JAG

    更新日期:2018-02-01 00:00:00

  • Marker characteristics of Venezuelan encephalitis virus strains isolated before and after epidemics and equine epizootics in Middle America.

    abstract::Ninety-four strains of Venezuelan encephalitis (VE) virus isolated from sentinel hamsters exposed in the Middle American countries of Mexico, Guatemala, Belize, and Honduras were examined for the presence of virions with marker characteristics of strains that cause large epidemics and equine epizootics. Thirty-four st...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113531

    authors: Wiebe ME,Scherer WF,Peick WJ

    更新日期:1983-02-01 00:00:00

  • A validation of two motion sensors in the prediction of child and adult physical activity levels.

    abstract::The authors sought to assess the reliability and validity of two motion activity sensors in the prediction of observed physical activity levels in adults and children by means of two studies at North Dakota State University in Fargo, North Dakota. In study 1, 50 adults were observed in fall 1984 for one hour of recrea...

    journal_title:American journal of epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.aje.a114121

    authors: Klesges RC,Klesges LM,Swenson AM,Pheley AM

    更新日期:1985-09-01 00:00:00

  • Growth trajectories and intellectual abilities in young adulthood: The Helsinki Birth Cohort study.

    abstract::Slow childhood growth is associated with poorer intellectual ability. The critical periods of growth remain uncertain. Among 2,786 Finnish male military conscripts (1952-1972) born in 1934-1944, the authors tested how specific growth periods from birth to age 20 years predicted verbal, visuospatial, and arithmetic abi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwp132

    authors: Räikkönen K,Forsén T,Henriksson M,Kajantie E,Heinonen K,Pesonen AK,Leskinen JT,Laaksonen I,Osmond C,Barker DJ,Eriksson JG

    更新日期:2009-08-15 00:00:00

  • Prescription medications associated with a decreased risk of non-Hodgkin's lymphoma.

    abstract::Earlier epidemiologic studies have suggested an inverse association between non-Hodgkin's lymphoma and exposure to histamine(2) (H(2)) blockers, nonsteroidal anti-inflammatory drugs, cholesterol-lowering drugs, and antibiotics. Data from the PHARMO database were used to conduct a nested, population-based case-control ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwg004

    authors: Beiderbeck AB,Holly EA,Sturkenboom MC,Coebergh JW,Stricker BH,Leufkens HG

    更新日期:2003-03-15 00:00:00

  • Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus.

    abstract::Large-scale genome-wide association studies (GWAS) have identified over 40 genomic regions significantly associated with type 2 diabetes mellitus. However, GWAS results are not always straightforward to interpret, and linking these loci to meaningful disease etiology is often difficult without extensive follow-up stud...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws123

    authors: Greenawalt DM,Sieberts SK,Cornelis MC,Girman CJ,Zhong H,Yang X,Guinney J,Qi L,Hu FB

    更新日期:2012-09-01 00:00:00

  • Paternal occupation and anencephaly.

    abstract::It has been suggested that paternal occupational exposures to pesticides and solvents increase the risk of neural tube defects in offspring. With the use of Texas livebirth, fetal death, and linked livebirth-death records, the authors conducted a population-based case-control study among 1981-1986 Texas births to exam...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115526

    authors: Brender JD,Suarez L

    更新日期:1990-03-01 00:00:00

  • Using intake biomarkers to evaluate the extent of dietary misreporting in a large sample of adults: the OPEN study.

    abstract::This paper describes the Observing Protein and Energy Nutrition (OPEN) Study, conducted from September 1999 to March 2000. The purpose of the study was to assess dietary measurement error using two self-reported dietary instruments-the food frequency questionnaire (FFQ) and the 24-hour dietary recall (24HR)-and unbias...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwg092

    authors: Subar AF,Kipnis V,Troiano RP,Midthune D,Schoeller DA,Bingham S,Sharbaugh CO,Trabulsi J,Runswick S,Ballard-Barbash R,Sunshine J,Schatzkin A

    更新日期:2003-07-01 00:00:00

  • Acquired immunodeficiency syndrome (AIDS) risk in recent and long-standing human immunodeficiency virus type 1 (HIV-1)-infected patients with similar CD4 lymphocyte counts.

    abstract::The loss of CD4 lymphocytes is known to be an important component of human immunodeficiency virus type 1 (HIV-1) pathogenesis. It remains unclear, however, whether the importance of the CD4 lymphocyte count is such that individuals who have been infected for widely different lengths of time, but for whom the CD4 lymph...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116789

    authors: Phillips AN,Sabin CA,Elford J,Bofill M,Janossy G,Lee CA

    更新日期:1993-11-15 00:00:00

  • "If it isn't ultimately aimed at policy, it's not worth doing": interview of George W. Comstock by Alfredo Morabia.

    abstract::George W. Comstock (1915-2007), MD, MPH, DrPH, was lecturer and then professor of epidemiology at the Johns Hopkins University School of Hygiene and Public Health from 1956 to 2007 and served as editor-in-chief of the American Journal of Epidemiology from 1979 to 1988. This interview of George W. Comstock took place i...

    journal_title:American journal of epidemiology

    pub_type: 传,历史文章,面试

    doi:10.1093/aje/kwt027

    authors: Morabia A

    更新日期:2013-04-01 00:00:00

  • Mesothelioma trends in the United States: an update based on Surveillance, Epidemiology, and End Results Program data for 1973 through 2003.

    abstract::Using 1973-2000 mesothelioma incidence data released by the Surveillance, Epidemiology, and End Results Program in April 2003, the authors estimated the parameters of a birth-cohort and age model to determine whether previously reported patterns of mesothelioma in the United States have changed. Compared with analyses...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh025

    authors: Price B,Ware A

    更新日期:2004-01-15 00:00:00