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2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions.

Abstract：

:2('),3(')-Didehydro-2('),3(')-dideoxynucleosides are clinically relevant antiviral agents. These nucleosides could be degraded under acidic conditions. Acidic stability studies showed the D4N had the following increasing stability order: D4G

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Shi J,Ray AS,Mathew JS,Anderson KS,Chu CK,Schinazi RF

doi

10.1016/j.bmcl.2004.02.031

subject

Has Abstract

pub_date

2004-05-03 00:00:00

pages

2159-62

issue

9

eissn

0960-894X

issn

1464-3405

pii

S0960894X04002343

journal_volume

14

pub_type

杂志文章

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