MicroRNAs: something important between the genes.

Abstract:

:Non-coding small endogenous RNAs, of 21-24 nucleotides in length, have recently emerged as important regulators of gene expression in both plants and animals. At least three categories of small RNAs exist in plants: short interfering RNAs (siRNAs) deriving from viruses or transgenes and mediating virus resistance or transgene silencing via RNA degradation; siRNAs deriving from transposons or transgene promoters and controlling transposon and transgene silencing probably via chromatin changes; and microRNAs (miRNAs) deriving from intergenic regions of the genome and regulating the expression of endogenous genes either by mRNA cleavage or translational repression. The disruption of miRNA-mediated regulation causes developmental abnormalities in plants, demonstrating that miRNAs play an important role in the regulation of developmental decisions.

journal_name

Curr Opin Plant Biol

authors

Mallory AC,Vaucheret H

doi

10.1016/j.pbi.2004.01.006

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

120-5

issue

2

eissn

1369-5266

issn

1879-0356

pii

S1369526604000093

journal_volume

7

pub_type

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