The perception of gibberellins: clues from receptor structure.

Abstract:

:The discovery of GID1, a soluble receptor for gibberellins (GAs), has revealed new insights into how GA is perceived. X-ray analysis has demonstrated similarities in the tertiary structure of GID1 to hormone sensitive lipase (HSL), and the GA-binding pocket of GID1 corresponds to the active site of HSL. X-ray analysis has also revealed the structural basis of the GA-GID1 interaction, and evolutionary aspects of GID1 have been discovered by comparison to GID1 from non-flowering plants. Recent studies have also demonstrated the complexity of GA signaling in Arabidopsis, which is mediated by three GID1 and five DELLA proteins. Finally, mechanistic and structural similarities for hormone signaling are compared for GA, auxin and abscisic acid, three hormones where the receptor protein structure was recently described.

journal_name

Curr Opin Plant Biol

authors

Ueguchi-Tanaka M,Matsuoka M

doi

10.1016/j.pbi.2010.08.004

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

503-8

issue

5

eissn

1369-5266

issn

1879-0356

pii

S1369-5266(10)00106-8

journal_volume

13

pub_type

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