Abstract:
:Quantification of genotype-to-phenotype associations is central to many scientific investigations, yet the ability to obtain consistent results may be thwarted without appropriate statistical analyses. Models for association can consider confounding effects in the materials and complex genetic interactions. Selecting optimal models enables accurate evaluation of associations between marker loci and numerous phenotypes including gene expression. Significant improvements in QTL discovery via association mapping and acceleration of breeding cycles through genomic selection are two successful applications of models using genome-wide markers. Given recent advances in genotyping and phenotyping technologies, further refinement of these approaches is needed to model genetic architecture more accurately and run analyses in a computationally efficient manner, all while accounting for false positives and maximizing statistical power.
journal_name
Curr Opin Plant Bioljournal_title
Current opinion in plant biologyauthors
Lipka AE,Kandianis CB,Hudson ME,Yu J,Drnevich J,Bradbury PJ,Gore MAdoi
10.1016/j.pbi.2015.02.010subject
Has Abstractpub_date
2015-04-01 00:00:00pages
110-8eissn
1369-5266issn
1879-0356pii
S1369-5266(15)00030-8journal_volume
24pub_type
杂志文章,评审abstract::Endogenous peptide ligand-receptor systems regulate cell-cell communications in various developmental processes in plants. Recent studies have revealed that the peptide-receptor combinations are not simply one-on-one with single roles. One peptide activates multiple downstream signaling through different receptors, wh...
journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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abstract::Embryogenesis is a critical stage of the sporophytic life cycle during which the basic body plan of the plant is established. Although positional information is implicated to play a major role in determining embryo cell fate, little is known about the nature of positional signals. Recent studies show that the monopter...
journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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abstract::Successful penetration of living plant tissue by fungal pathogens is preceded by an exchange of signals between both organisms. Recent mutational approaches revealed the importance of cAMP-dependent signalling pathways for fungal development and virulence on their hosts. ...
journal_title:Current opinion in plant biology
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journal_title:Current opinion in plant biology
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abstract::Variation in grass architecture profoundly affects light capture, competition, and reproductive success, and is responsive to environmental factors such as crowding and nutrient limitation. Recent work in both model and crop systems has uncovered many aspects of the genetic control of branching, including conservation...
journal_title:Current opinion in plant biology
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