Abstract：
:Recent advances in DNA targeting allow unprecedented control over gene function and expression. Targeting based on TAL effectors is arguably the most promising for systems biology and metabolic engineering. Multiple, orthogonal TAL-effector reagents of different types can be used in the same cell. Furthermore, variation in base preferences of the individual structural repeats that make up the TAL effector DNA recognition domain makes targeting stringency tunable. Realized applications range from genome editing to epigenome modification to targeted gene regulation to chromatin labeling and capture. The principles that govern TAL effector DNA recognition make TAL effectors well suited for applications relevant to plant physiology and metabolism. TAL effector targeting has merits that are distinct from those of the RNA-based DNA targeting CRISPR/Cas9 system.
journal_name
Curr Opin Plant Bioljournal_title
Current opinion in plant biologyauthors
Bogdanove AJdoi
10.1016/j.pbi.2014.05.007subject
Has Abstractpub_date
2014-06-01 00:00:00pages
99-104eissn
1369-5266issn
1879-0356pii
S1369-5266(14)00063-6journal_volume
19pub_type
杂志文章abstract：:Nitrogen (N) and Phosphorus (P) are the two most essential nutrients ensuring food production and security. The ever growing population demands more N and P-based fertilizers. Even though the N provision to the agricultural system is virtually infinite (Haber and Bosch process) it triggers pollution when it is not use...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2020.07.002
更新日期：2020-10-01 00:00:00
abstract：:Parent-of-origin dependent gene expression refers to differential activity of alleles inherited from the egg and sperm. In plants, zygotic genome activation (ZGA) and gene imprinting are two examples of this phenomenon, both of which occur during seed development. As its name implies, ZGA is a genome-wide process that...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2015.05.020
更新日期：2015-10-01 00:00:00
abstract：:Residing beneath the phenotypic landscape of a plant are intricate and dynamic networks of genes and proteins. As evolution operates on phenotypes, we expect its forces to shape somehow these underlying molecular networks. In this review, we discuss progress being made to elucidate the nature of these forces and their...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2012.01.006
更新日期：2012-04-01 00:00:00
abstract：:Agriculture faces enormous challenges including the need to substantially increase productivity, reduce environmental footprint, and deliver renewable alternatives that are being addressed by developing new oil crops for the future. The efforts include domestication of Lepidium spp. using genomics-aided breeding as a ...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2019.12.003
更新日期：2020-08-01 00:00:00
abstract：:Given the prevalence of duplicate genes and genomes in plant species, the study of their evolutionary dynamics has been a focus of study in plant evolutionary genetics over the past two decades. The past few years have been a particularly exciting time because recent theoretical and experimental investigations have le...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2004.12.001
更新日期：2005-04-01 00:00:00
abstract：:With a size approximating that of the human genome, the maize genome is about to become the largest plant genome yet sequenced. Contributing to that size are a whole-genome duplication event and a retrotransposition explosion that produced a large amount of repetitive DNA. This DNA is greatly under-represented in cDNA...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2006.01.009
更新日期：2006-04-01 00:00:00
abstract：:The genome of the plastid has generated much interest as a target for plant transformation. The characteristics of plastid transgenes both reflect the prokaryotic origin of plastid organelles and provide a unique set of features that are currently lacking in genes introduced into the plant nucleus. Recent progress has...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5266(00)00153-9
更新日期：2001-04-01 00:00:00
abstract：:Pattern recognition receptors (PRRs) enable plants to sense non-self molecules displayed by microbes to mount proper defense responses or establish symbiosis. In recent years the importance of PRR subcellular trafficking to plant immunity has become apparent. PRRs traffic through the endoplasmatic reticulum (ER) and t...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2012.05.004
更新日期：2012-08-01 00:00:00
abstract：:Cysteine and serine proteases are prominent players in the control of developmental and pathogen-activated cell deaths in plants. Ethylene, salicylic acid, the small G-protein Rac, calcium and reactive oxygen species are recurring mediators of death signaling. Lastly, the mitochondrion has emerged in both plant and an...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5266(99)00026-6
更新日期：1999-12-01 00:00:00
abstract：:Developmental pathways are often simplified as linear cascades of gene activation caused by initial signaling events. Recent data, however, support a more complex view in which non-linear responses to signals are important for pattern formation. First, a positive feedback loop may regulate cellular patterning in the A...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5266(00)00105-9
更新日期：2000-10-01 00:00:00
abstract：:Completion of the genomic sequencing of rice has enhanced the discovery of new genes. Wild rice relatives are good sources for extending the genetic variation of cultivated rice. Reproductive barriers are commonly found in distant crosses of rice and are attracting attention. The combination of genetic analyses and mo...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2008.01.008
更新日期：2008-04-01 00:00:00
abstract：:During the past decade, molecular genetic studies on the reference plant Arabidopsis have established a largely linear signal transduction pathway for the response to ethylene gas. The biochemical modes of action of many of the signaling components are still unresolved. During the past year, however, progress in sever...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2003.11.011
更新日期：2004-02-01 00:00:00
abstract：:Centrosomes play various critical roles in animal cells such as microtubule nucleation and stabilization, mitotic spindle morphogenesis, and spindle orientation. Land plants have lost centrosomes and yet must execute many of these functions. Recent studies have revealed the crucial roles played by morphologically dist...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2018.06.004
更新日期：2018-12-01 00:00:00
abstract：:Acylsugars are insecticidal plant specialized metabolites produced in the Solanaceae (nightshade family). Despite having simple constituents, these compounds are unusually structurally diverse. Their structural variations in phylogenetically closely related species enable comparative biochemical approaches to understa...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2019.03.005
更新日期：2019-06-01 00:00:00
abstract：:During the past two years, significant progress has been made towards understanding the molecular basis of how multiple pathways regulating the floral transition are integrated. The transcriptional regulation of several genes, the floral meristem identity gene LEAFY and the 'flowering-time' genes FLOWERING LOCUS T and...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5266(00)00137-0
更新日期：2001-02-01 00:00:00
abstract：:In nature, plants interact with numerous other organisms. Some interactions benefit both the plant and the other organism(s), while others lead to disease or even death of the plant hosts. The traditional focus of research into plant biotic interactions has been on the negative effects on plants and the strategies pla...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2019.06.002
更新日期：2019-08-01 00:00:00
abstract：:Throughout the eukaryotic world, kinesins serve as molecular motors for the directional transport of cellular cargo along microtubule tracks. Plants contain a large number of kinesins that have conserved as well as specialized functions. These functions depend on mechanisms that regulate when, where and what kinesins ...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2013.09.003
更新日期：2013-12-01 00:00:00
abstract：:Plants have acquired the ability for organized multicellular development independent from animals. Because of this, they represent an independent example in nature for the development of coordinated, complex cell polarity from the simple polarity found in unicellular eukaryotes. Plants display a striking array of pola...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2008.09.009
更新日期：2009-02-01 00:00:00
abstract：:Linalool (3,7-dimethyl-1,6-octadien-3-ol) is a common floral volatile with two distinct enantiomers and related metabolites involved in the full spectrum of plant-pollinator interactions. Recent studies reveal a complex interplay between pollinator attraction and plant defense mediated by linalool and its derivatives,...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2016.05.007
更新日期：2016-08-01 00:00:00
abstract：:Plant diseases threaten global food security and biodiversity. Rapid dispersal of pathogens particularly via human means has accelerated in recent years. Timely detection of plant pathogens is essential to limit their spread. At the same time, international regulations must keep abreast of advances in plant disease di...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2020.04.011
更新日期：2020-08-01 00:00:00
abstract：:Plants use robust mechanisms to optimize organ size to prevailing conditions. Modulating the transition from cell division to elongation dramatically affects morphology and size. Although it is well established that auxin, cytokinin and brassinosteroid mediate these transitions, recent works show that the cytoskeleton...
journal_title：Current opinion in plant biology
pub_type： 杂志文章
doi：10.1016/j.pbi.2014.11.003
更新日期：2014-12-01 00:00:00
abstract：:A large proportion of the genes in any plant genome encode enzymes of primary and specialized (secondary) metabolism. Not all plant primary metabolites, those that are found in all or most species, have been identified. Moreover, only a small portion of the estimated hundreds of thousand specialized metabolites, those...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2005.03.004
更新日期：2005-06-01 00:00:00
abstract：:Methylation of histones on different lysine residues is dynamically added by distinct writer enzymes, interpreted by reader proteins, and removed by eraser enzymes. This epigenetic mark has widespread, dynamic roles in plant development and environmental responses. For example, histone methylation plays a key role in ...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2021.102001
更新日期：2021-01-25 00:00:00
abstract：:Unveiling of hormone perception is central to comprehending hormone action. It is generally recognized that an active hormone molecule binds its receptor to initiate hormone signaling, subsequently dissociates from its receptor without being changed, and then initiates the next round of hormone perception. However, re...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2018.06.007
更新日期：2018-10-01 00:00:00
abstract：:The basic mechanism of mitosis is universally conserved in all eucaryotes, but specific solutions to achieve this process have been adapted by different organisms during evolution. Although cytological studies of plant cells have contributed to our understanding of chromatin dynamics during mitosis, many of the molecu...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5266(02)00297-2
更新日期：2002-12-01 00:00:00
abstract：:During the past year, significant advances have been made in our understanding of stomatal development and its response to climate change, and in our knowledge of how guard cell Ca(2+) oscillations encode environmental signals. Recent studies on (de)phosphorylation mechanisms have provided new information on how guard...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5266(00)00195-3
更新日期：2001-10-01 00:00:00
abstract：:In plant innate immunity, the first line of microbial recognition leading to active defence responses relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs). This recognition leads to PAMP-triggered immunity (PTI). Despite the numerous PAMPs recognised by pla...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2009.06.003
更新日期：2009-08-01 00:00:00
abstract：:In the last two decades, work on auxin signaling has helped to understand many aspects of the fundamental process underlying the specification of tissue types in the plant embryo. However, the immediate steps after fertilization including the polarization of the zygote and the initial body axis formation remained poor...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2019.10.002
更新日期：2020-02-01 00:00:00
abstract：:The arbuscular mycorrhiza (AM) is a symbiosis between most terrestrial plants and fungi of the ancient phylum Glomeromycota. AM improves the uptake of water and mineral nutrients, such as phosphorus (P) and nitrogen (N), of the host plant in exchange for photosynthetically fixed carbon. Successful colonization and a f...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2009.06.001
更新日期：2009-08-01 00:00:00
abstract：:The sessile nature of plants has caused plants to develop means to defend themselves against attacking organisms. Multiple strategies range from physical barriers to chemical warfare including pre-formed anticipins as well as phytoalexins produced only upon attack. While phytoalexins require rapid induction, constitut...
journal_title：Current opinion in plant biology
pub_type： 杂志文章,评审
doi：10.1016/j.pbi.2017.04.009
更新日期：2017-08-01 00:00:00
