Abstract:
BACKGROUND:Granular parakeratosis is a hyperkeratotic eruption of unknown etiology that occurs in the axilla and other intertriginous areas. The histologic features are unique for the retention of keratohyalin granules in the stratum corneum. OBJECTIVE:The aim of the article is to review the clinical manifestations and treatment of granular parakeratosis. METHODS:A case report and literature review are presented. RESULTS:Twenty-six cases of granular parakeratosis now have been reported and reviewed. CONCLUSION:Granular parakeratosis occurs predominantly in middle age women and most frequently in the axilla. A number of treatments have been applied to the 26 cases reported to date, without consistent responses. No evidence-based therapy can be suggested at present.
journal_name
J Cutan Med Surgjournal_title
Journal of cutaneous medicine and surgeryauthors
English JC 3rd,Derdeyn AS,Wilson WM,Patterson JWdoi
10.1007/s10227-002-0131-4subject
Has Abstractpub_date
2003-07-01 00:00:00pages
330-2issue
4eissn
1203-4754issn
1615-7109journal_volume
7pub_type
杂志文章,评审abstract:BACKGROUND:The onychodystrophies associated with Sézary syndrome (SzS) have rarely been described in the literature. We performed a retrospective analysis of SzS patients at a single institution and compared our data with previous publications. OBJECTIVES:The objectives of this study were to identify and describe the ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475419839937
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Lichen amyloidosis, a type of primary localized cutaneous amyloidosis, is characterized by pruritic brown or grayish pigmented papules. OBJECTIVE:We report a case of lichen amyloidosis in which the skin lesion consisted of asymptomatic salmon-pink-colored papules on the back of the neck to the upper back. T...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1007/s10227-001-0052-7
更新日期:2002-07-01 00:00:00
abstract::Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475418777734
更新日期:2018-09-01 00:00:00
abstract::The Maintenance of Certification (MOC) Program administered by the Royal College of Physicians and Surgeons applies to all Fellows of the Royal College including dermatologists. It is mandatory for those who wish to maintain their fellowship in the Royal College and can be critical for maintaining licensure requiremen...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417709194
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES:Our study's objectives were t...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417708163
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Keratoelastoidosis marginalis is a rare disease that is a variant of solar elastosis. Long-term ultraviolet radiation exposure and chronic trauma secondary to manual labor are considered to be inciting factors. OBJECTIVE:To outline the clinical and histological features of this disorder. METHODS:We report ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1007/s10227-001-0025-x
更新日期:2002-01-01 00:00:00
abstract::The association between isotretinoin and atypical wound healing remains controversial. It is common practice to delay elective procedures for 6 to 24 months after oral isotretinoin therapy. The studies supporting common practices (SCP) recommend extending this period to include the 6 to 24 months preceding treatment. ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475417701419
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Dermoscopy has been shown to be a promising method to facilitate the diagnosis of lichen planus (LP) outside of China. OBJECTIVE:To investigate the spectrum of dermoscopic patterns in Chinese LP patients. METHODS:The clinical data and dermoscopic patterns of nine LP cases with a total of 43 lesions were ev...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2013.13049
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Skin cancer is extremely common. Epidemiological studies indicated that ultraviolet radiation (UV) is the primary cause for skin cancers, and that retinoic acid (RA) is able to inhibit this UV-induced skin carcinogenesis; however, the molecular mechanism of the anti-UV action of RA is unclear. OBJECTIVE:The...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/120347540000400102
更新日期:2000-01-01 00:00:00
abstract::Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semi...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417712498
更新日期:2017-09-01 00:00:00
abstract::Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475417736278
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:To date, there is no standard treatment of folliculitis decalvans (FD), a rare type of cicatricial alopecia. OBJECTIVE AND METHODS:The records of 23 patients with FD (1998-2012) were retrospectively analyzed, with added data review on the course and treatment of long-standing cases. RESULTS:Initial managem...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
abstract::Psoriasis is a common inflammatory disease with significant comorbidities, whose management can be challenging given the variety of treatment options. It is critical for nurse practitioners, physician assistants, general practitioners, and dermatology trainees to have useful information about the treatment and monitor...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475415623508
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Merkel cell carcinoma is a rare, aggressive, malignant cutaneous tumor of the elderly or immunosuppressed individuals that usually appears on sun-exposed areas of the body. Its pathogenesis is still debated, and, currently, no standardized treatment exists. OBJECTIVE:To provide a current updated review of t...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.2310/7750.2010.09017
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Onychomycosis has several clinical presentations and is caused by various infectious organisms. OBJECTIVE:To provide guidance for selection of appropriate treatment. METHODS:The literature on onychomycosis management was reviewed to generate an evidence-based decision tree. RESULTS AND CONCLUSION:Several ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.2310/7750.2014.14090
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475416670368
更新日期:2017-01-01 00:00:00
abstract::We present the extraordinary case of a 72-year-old man with a history of primary cutaneous peripheral T-cell lymphoma not otherwise specified (pcPTCL-NOS) previously controlled with topical agents who developed tumours in a sporotrichoid pattern. Culture of the tumours was negative, and histopathology showed findings ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417721425
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:In addition to corticosteroids, there are increasing numbers of anti-inflammatory agents that specifically target bioactive lipids generated from arachidonic acid. Knowledge of the diverse mechanisms of action of these different bioactive lipids holds promise in the therapy of a wide spectrum of cutaneous an...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1007/s10227-001-0047-4
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:All kinds of bees, wasps, and hornets are members of the hymenoptera order. Local hypersensitivity reactions after bee stings are very common and well studied. However, tissue necroses following untreated bee stings are extremely rare and they are not well documented. OBJECTIVE:Two extremely rare cases of e...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/120347540300700207
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Forty-nine years ago the first complete and authoritative English text on the physiology and biochemistry of the skin was published by Stephen Rothman, an early basic researcher in dermatology. OBJECTIVE:The purpose of the article is to learn more about Stephen Rothman and his 1954 text, to learn more about...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 传,历史文章,杂志文章
doi:10.1007/s10227-005-0040-4
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:In 1997, it was reported that a PTEN gene deletion, a common genetic mutation in Cowden's disease (CD), was identified in a patient with Bannayan-Riley-Ruvacalba (BRR), suggesting that the two diseases were allelic. However, the clinical overlap between the two diseases has largely remained unclear. OBJECTI...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/120347540100500307
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Onychomycosis is a persistent fungal nail infection that is notoriously hard to treat. Approximately 20% to 25% of patients with onychomycosis do not respond to treatment, and 10% to 53% of patients relapse. As such, successful treatment is imperative for long-term disease management. OBJECTIVE:To identify ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475416653734
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Pemphigus vegetans is a rare variant of pemphigus vulgaris, comprising 1 to 2% of all pemphigus cases. Exposures to oral agents such as captopril and penicillamine and, less commonly, physical or chemical factors have been implicated in the development of pemphigus. METHODS:We report a 42-year-old white mal...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/120347541201600512
更新日期:2012-09-01 00:00:00
abstract::A renaissance is taking place in the field of wound healing. Interest in wounds has probably never been so great, and a number of key therapeutic advances in the last 2 or 3 years are only an indication of more progress to come. In large part, we are benefitting from decades of basic research that has provided the kno...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Optimal aesthetic results are achieved when nasal defects after Mohs micrographic surgery (MMS) are reconstructed as entire nasal subunits. OBJECTIVE:To illustrate the importance of reconstructing the nose in entire subunits and explore the possibilities of expanding the principles of subunit reconstruction...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475416629594
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Patient nonattendance is a frequent occurrence in dermatology clinics, and our responsibility regarding the follow-up of these patients remains nebulous. OBJECTIVE:This study sought to evaluate the beliefs and practices of physicians at a university-affiliated medical dermatology clinic regarding patient no...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2011.11004
更新日期:2012-03-01 00:00:00
abstract::Larva currens is the cutaneous manifestation of human infection with the geotropic helminth Strongyloides stercoralis. Strongyloidiasis is a lifelong infection unless treated. A high index of suspicion is needed to prevent chronic symptoms of strongyloidiasis (eg, larva currens, eosinophilia, abdominal discomfort) and...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475415575247
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475416651605
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Biologics have transformed the management of moderate to severe psoriasis. The persistency of biologics lacks real-world data. OBJECTIVES:To quantify drug survival of infliximab (IFX), adalimumab (ADA), etanercept (ETA), and ustekinumab (UST) and to identify potential factors affecting drug survival. METHO...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417733957
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Amyloidosis refers to a group of depositional diseases that are classified into two main types: systemic and localized. Large nodules of localized cutaneous amyloidosis of the nasal ala and surrounding skin are rare and the treatment is often unsatisfactory. OBJECTIVE:We report a case of rapidly enlarging, ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02737862
更新日期:2001-03-01 00:00:00