Arachidonic acid-derived bioactive lipids: their role and the role for their inhibitors in dermatology.

abstract：BACKGROUND:Local skin reactions are common during imiquimod treatment of actinic keratosis (AK). Cyclical application of imiquimod may improve tolerability while maintaining efficacy. OBJECTIVE:To assess the tolerability of imiquimod and clearance rate of AK lesions after imiquimod application. METHODS:Imiquimod 5% c...

journal_title：Journal of cutaneous medicine and surgery

authors： Rivers JK,Rosoph L,Provost N,Bissonnette R

更新日期：2008-05-01 00:00:00

abstract：:Acne vulgaris, a condition that can affect people at any age, is the most common cause of referral to a dermatologist. Isotretinoin (ITT) is the most effective treatment available, but serious adverse effects, including a possible association with depression and suicide, limit its use. We review the current literature...

journal_title：Journal of cutaneous medicine and surgery

authors： Oliveira JM,Sobreira G,Velosa J,Telles Correia D,Filipe P

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This is a somewhat rare case of a 19-year-old African American female with multiple cutaneous granular cell tumors. Granular cell tumors are of neural origin, except in rare cases, and are considered benign, with a low incidence of malignancy. The clinical presentation varies greatly, but these...

journal_title：Journal of cutaneous medicine and surgery

authors： Henry M,Perry A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Encephalocraniocutaneous lipomatosis (ECCL) is a relatively new, nonhereditary, but congenital, neurocutaneous syndrome with unilateral cutaneous tumors and ipsilateral ophthalmologic and neurologic malformations. The syndrome is rare, with only 25 cases reported since first communication in 1970. The primar...

journal_title：Journal of cutaneous medicine and surgery

authors： Gawel J,Schwartz RA,Józwiak S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is an autoimmune polymorphic skin disease characterized by erythematous papules and plaques and tense bullae. A skin biopsy for direct immunofluorescence (DIF) is used to detect autoantibodies and complement proteins. OBJECTIVE:We sought to determine which location would provide the ...

journal_title：Journal of cutaneous medicine and surgery

authors： Sladden C,Kirchhof MG,Crawford RI

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Dermatofibrosarcoma protuberans with fibrosarcomatous differentiation (DFSP-FS) is a rare variant of DFSP with a more aggressive clinical course, characterized by higher rates of local recurrence, metastasis, and death. METHODS:We conducted a clinicopathologic review of all DFSP-FS cases that occurred in Al...

journal_title：Journal of cutaneous medicine and surgery

authors： Kuzel P,Mahmood MN,Metelitsa AI,Salopek TG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The self-inflicted dermatoses such as acne excorieé and neurotic excoriations are often chronic, recurring, and resistant to standard dermatologic therapies. OBJECTIVE:We present a 28-year-old woman with longstanding acne excorieé, whose acne started at age 14 years and was followed by acne excorieé at age ...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta MA,Gupta AK

更新日期：2001-01-01 00:00:00

abstract：:Psoriasis has been associated with a number of behavioral and systemic comorbidities, including psoriatic arthritis, anxiety, depression, obesity, hypertension, diabetes mellitus, hyperlipidemia, metabolic syndrome, smoking, cardiovascular disease, alcoholism, Crohn's disease, lymphoma, and multiple sclerosis. Many of...

journal_title：Journal of cutaneous medicine and surgery

authors： Guenther L,Gulliver W

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Plaque psoriasis (PsO) is a chronic inflammatory disease that often presents at peak reproductive age in women of child-bearing potential (WOCBP). With the emergence of biologic therapies to treat PsO, guidance on disease management in WOCBP is needed to inform treatment decisions before, during, and after p...

journal_title：Journal of cutaneous medicine and surgery

authors： Yeung J,Gooderham MJ,Grewal P,Hong CH,Lansang P,Papp KA,Poulin Y,Turchin I,Vender R

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

journal_title：Journal of cutaneous medicine and surgery

authors： AbuHilal M,Walsh S,Shear N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is believed to be a follicular variant of lichen planus that affects pilosebaceous units, mainly of the scalp. An extremely rare variant of LPP is a linear form, which follows the lines of Blaschko. Of the five previously documented cases of linear LPP, all were limited to the face....

journal_title：Journal of cutaneous medicine and surgery

authors： Baker K,Pehr K

更新日期：2006-05-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladha MA,Haber RM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Dermoscopy has been shown to be a promising method to facilitate the diagnosis of lichen planus (LP) outside of China. OBJECTIVE:To investigate the spectrum of dermoscopic patterns in Chinese LP patients. METHODS:The clinical data and dermoscopic patterns of nine LP cases with a total of 43 lesions were ev...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan C,Min ZS,Xue Y,Zhu WY

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Whereas several literature reviews have discussed the role of excipients in drug-related reactions, no article has focused specifically on those found in oral dermatologic medications. METHODS:The Compendium of Pharmaceuticals and Specialties (CPS) was used to reference the inert ingredients found in oral d...

journal_title：Journal of cutaneous medicine and surgery

authors： Noiles K,Vender R

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Ear keloids continue to be a therapeutic challenge. OBJECTIVE:To evaluate the clinical success of a modified "oyster splint technique." METHODS:Ten patients with an ear keloid agreed to receive the compression therapy. After surgical removal, a compressive device made of acrylic resin was applied on top of...

journal_title：Journal of cutaneous medicine and surgery

authors： Hassel JC,Löser C,Koenen W,Kreuter A,Hassel AJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lacroix JP,Wang B

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The number of dermatology residency positions in Canada has not reflected the growing workforce shortage. Until 2005, all dermatology residents at the University of Ottawa were committed to return to their funding area at the completion of their training. This has left Eastern Ontario with a critical shortag...

journal_title：Journal of cutaneous medicine and surgery

authors： Heughan C,Kanigsberg N,Amdemichael E,Fergusson D,Ammerman D

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Pyodermatitis-pyostomatitis vegetans (PDPSV) is a rare inflammatory disorder of the skin and oral mucosa that is commonly associated with inflammatory bowel disease (IBD). Ocular involvement is uncommon. OBJECTIVE:Given the association with IBD, it is important for dermatologists to be aware of the varying ...

journal_title：Journal of cutaneous medicine and surgery

authors： Dupuis EC,Haber RM,Robertson LH

更新日期：2016-03-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

journal_title：Journal of cutaneous medicine and surgery

authors： Thomas MG,Betsy A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Round and oval skin wounds, like facial pigmented nevi after excision, are traditionally sutured linearly for closure, leaving significant scars, which greatly influences their appearance. OBJECTIVE:This article provides an overview of our experience using intradermal purse-string suture for round and oval ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhu JW,Wu XJ,Lu ZF,Cai SQ,Zheng M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Although betamethasone valerate (BMV) foam, 0.12% (Luxiq, Connectics Corporation, Palo Alto, CA) is approved by the Food and Drug Administration for the treatment of corticosteroid-responsive scalp dermatoses, no data are available for its use on nonscalp psoriasis. OBJECTIVE:We evaluated the safety and eff...

journal_title：Journal of cutaneous medicine and surgery

authors： Stein LF,Sherr A,Solodkina G,Gottlieb AB,Chaudhari U

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES:Our study's objectives were t...

journal_title：Journal of cutaneous medicine and surgery

authors： Lara-Corrales I,Moazzami M,García-Romero MT,Pope E,Parkin P,Shugar A,Kannu P

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The gtring presence of dermatology platforms on Facebook has been acknowledged; however, little is known about the extent to which different types of content influence the level of engagement with online users. OBJECTIVE:To assess the level of public engagement with different types of content posted on Face...

journal_title：Journal of cutaneous medicine and surgery

authors： Kim WB,Marinas JE,Vender RB

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Patient nonattendance is a frequent occurrence in dermatology clinics, and our responsibility regarding the follow-up of these patients remains nebulous. OBJECTIVE:This study sought to evaluate the beliefs and practices of physicians at a university-affiliated medical dermatology clinic regarding patient no...

journal_title：Journal of cutaneous medicine and surgery

authors： Nasseri E,Bertrand J,Brassard D,Fortier-Riberdy G,Marcil I

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Vemurafenib is an oral BRAF inhibitor recently approved for the treatment of metastatic melanoma. Patients treated with this medication have been reported to have the occurrence of squamous cell carcinoma (SCC) and/or actinic keratosis (AK). OBJECTIVE:We report the case of a patient treated with vemurafenib...

journal_title：Journal of cutaneous medicine and surgery

authors： Mays R,Curry J,Kim K,Tsai K,Arora A,Khan F,Ramirez-Fort M,Ciurea A

更新日期：2013-11-01 00:00:00

abstract：:The primary goal of treatment for external genital warts (EGWs) is to eradicate visible lesions and address symptoms that may accompany them, but it does not address the underlying virus. Left untreated, warts may grow, remain the same, or spontaneously regress as a result of being cleared by the immune system. Howeve...

journal_title：Journal of cutaneous medicine and surgery

authors： Vender R,Bourcier M,Bhatia N,Lynde C

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Giant basal cell carcinomas (GBCC) can demonstrate very malignant behavior and pose a surgical challenge. OBJECTIVE:To present a surgical technique utilizing Mohs and the resection of narrow bands of tissue to excise a GBCC that created a large facial defect of 5 cm × 2 cm. METHODS:A unique combination of ...

journal_title：Journal of cutaneous medicine and surgery

authors： Nolan K,Henry M,Shohet M,Elahi E,Marmur E

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Cryptococcosis is an opportunistic infection caused by the encapsulated yeast Cryptococcus neoformans. This ubiquitous organism has emerged as a frequent finding in immunosuppressed patients, especially those with underlying malignancies, organ transplants, and the acquired immune deficiency syndrome (AIDS)....

journal_title：Journal of cutaneous medicine and surgery

authors： Ingleton R,Koestenblatt E,Don P,Levy H,Szaniawski W,Weinberg JM

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa acquisita (EBA) is a chronic subepidermal blistering disease that is frequently resistant to therapy. OBJECTIVE:A 58-year-old man who had a one-year history of a bullous eruption involving the hands, forearms, trunk, scalp, and oral mucosa. Histopathology revealed a subepidermal bulla,...

journal_title：Journal of cutaneous medicine and surgery

authors： Hughes AP,Callen JP

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Fewer dermatologists than other clinical specialists are entering and being retained as physicians in the Canadian medical workforce. Studies suggest that dermatologist numbers may influence skin disease outcomes. No study has questioned whether the number of clinical dermatologists can influence academic pr...

journal_title：Journal of cutaneous medicine and surgery

authors： Canzi Lanzini R,Fallen RS,Wismer J,Lima HC

更新日期：2012-05-01 00:00:00