Severe bronchiolitis in children.

abstract：:Food allergy is a potentially life-threatening condition with no approved curative therapy. A number of food allergen immunotherapies are being investigated in phase II/III trials; however, these are limited in their ability to restore immune tolerance to food allergens and often result in high rates of allergic side ...

journal_title：Clinical reviews in allergy & immunology

authors： Virkud YV,Wang J,Shreffler WG

更新日期：2018-10-01 00:00:00

abstract：:Biological rhythms are fundamental for homeostasis and have recently been involved in the regulatory processes of various organs and systems. Circadian cycle proteins and hormones have a direct effect on the inflammatory response and have shown pro- or anti-inflammatory effects in animal models of autoimmune diseases....

journal_title：Clinical reviews in allergy & immunology

authors： Torres-Ruiz J,Sulli A,Cutolo M,Shoenfeld Y

更新日期：2017-08-01 00:00:00

abstract：:Asthma is the most common potentially serious medical problem to complicate pregnancy. Recent reports suggest that 7 of every 100 pregnant women suffer from asthma during pregnancy. Asthmatic women have been shown to be at an increased risk of complications during pregnancy. This may be secondary to inadequately contr...

journal_title：Clinical reviews in allergy & immunology

authors： Namazy JA,Schatz M

更新日期：2004-06-01 00:00:00

abstract：:Several factors have been associated with the development of asthma and asthma-related morbidity and mortality. Exposures in the environment such as allergens and air pollutants have traditionally been linked to the risk of asthma and asthma outcomes. More recent literature has identified chronic psychosocial stress a...

journal_title：Clinical reviews in allergy & immunology

authors： Barnthouse M,Jones BL

更新日期：2019-12-01 00:00:00

abstract：:With the implementation of vaccination programs and the use of antibiotics, developed countries have seen a decline in infection-related pediatric bronchiectasis. However, significant morbidity from bronchiectasis is still seen and both infectious and noninfectious causes of bronchiectasis in the pediatric population ...

journal_title：Clinical reviews in allergy & immunology

authors： Boren EJ,Teuber SS,Gershwin ME

更新日期：2008-04-01 00:00:00

abstract：:In the vast database of peer-reviewed articles, the number of 2018 papers published retrieved using the "autoimmunity" keyword remained unchanged compared with the brilliant results of 2017 while returning above a 5% share within the immunology field, after the brisk decrease of this ratio in 2017. As in the past 12 y...

journal_title：Clinical reviews in allergy & immunology

authors： Selmi C

更新日期：2019-06-01 00:00:00

abstract：:Glatiramer acetate (GA) significantly ameliorates multiple sclerosis and was initially discovered through its effects on the animal model experimental autoimmune encephalomyelitis (EAE). Guillain-Barré syndrome (GBS) is a relatively common demyelinating disease of peripheral nerves for which there is a parallel animal...

journal_title：Clinical reviews in allergy & immunology

authors： Aronovich R,Katzav A,Chapman J

更新日期：2012-04-01 00:00:00

abstract：:The functions of macrophages that lead to effective host responses are critical for protection against Staphylococcus aureus. Deep tissue-invading S. aureus initially countered by macrophages trigger macrophage accumulation and induce inflammatory responses through surface receptors, especially toll-like receptor 2 (T...

journal_title：Clinical reviews in allergy & immunology

authors： Wang YC,Ma HD,Yin XY,Wang YH,Liu QZ,Yang JB,Shi QH,Sun B,Gershwin ME,Lian ZX

更新日期：2016-12-01 00:00:00

abstract：:Illicit stimulants, such as cocaine, amphetamine, and their derivatives (e.g., "ecstasy"), continue to exact heavy toll on health care in both developed and developing countries. The US Department of Health and Human Service reported over one million illicit drug-related emergency department visits in 2010, which was ...

journal_title：Clinical reviews in allergy & immunology

authors： Tseng W,Sutter ME,Albertson TE

更新日期：2014-02-01 00:00:00

abstract：:Atherosclerosis is an inflammatory disease, and several antigens have been shown to activate the immune response and affect the development of atherogenesis. This suggests that modulation of the immune system could represent a useful approach to prevent and/or treat this disorder. A vaccination approach might be a use...

journal_title：Clinical reviews in allergy & immunology

authors： de Carvalho JF,Pereira RM,Shoenfeld Y

更新日期：2010-04-01 00:00:00

abstract：:The critical asthma syndrome (CAS) encompasses the most severe, persistent, refractory asthma patients for the clinician to manage. Personalized pharmacotherapy is necessary to prevent the next acute severe asthma exacerbation, not just the control of symptoms. The 2007 National Asthma Education and Prevention Program...

journal_title：Clinical reviews in allergy & immunology

authors： Albertson TE,Schivo M,Gidwani N,Kenyon NJ,Sutter ME,Chan AL,Louie S

更新日期：2015-02-01 00:00:00

abstract：:Contact dermatitis accounts for 95% of occupational skin disorders. Irritant contact dermatitis (ICD) is often caused by cumulative exposure to weak irritants, accounting for 80% of all cases of contact dermatitis. ICD can co-exist with atopic dermatitis (AD) and allergic contact dermatitis (ACD). Patients with AD and...

journal_title：Clinical reviews in allergy & immunology

authors： Bains SN,Nash P,Fonacier L

更新日期：2019-02-01 00:00:00

abstract：:Air pollution is defined as the presence of noxious substances in the air at levels that impose a health hazard. Thus, there has been long-standing interest in the possible role of indoor and outdoor air pollutants on the development of respiratory disease. In this regard, asthma has been of particular interest but ma...

journal_title：Clinical reviews in allergy & immunology

authors： Hassoun Y,James C,Bernstein DI

更新日期：2019-12-01 00:00:00

abstract：:Non-alcoholic steatohepatitis (NASH) is the progressive phenotype of non-alcoholic fatty liver disease associated with the metabolic syndrome. The existence of autoimmune features in NASH has been reported, but its significance remains unclear. We herein report the autoantibody profile of 54 patients with histological...

journal_title：Clinical reviews in allergy & immunology

authors： Tsuneyama K,Baba H,Kikuchi K,Nishida T,Nomoto K,Hayashi S,Miwa S,Nakajima T,Nakanishi Y,Masuda S,Terada M,Imura J,Selmi C

更新日期：2013-08-01 00:00:00

abstract：:Sarcoidosis has innumerable clinical manifestations, as the disease may affect every body organ. Furthermore, the severity of sarcoidosis involvement may range from an asymptomatic state to a life-threatening condition. This manuscript reviews a wide variety of common and less common clinical characteristics of sarcoi...

journal_title：Clinical reviews in allergy & immunology

authors： Judson MA

更新日期：2015-08-01 00:00:00

abstract：:G protein-coupled receptors (GPCRs) constitute the largest family of plasma membrane receptors in nature and mediate the effects of a variety of extracellular signals, such as hormone, neurotransmitter, odor, and light signals. Due to their involvement in a broad range of physiological and pathological processes and t...

journal_title：Clinical reviews in allergy & immunology

authors： Zhao M,Wang Z,Yang M,Ding Y,Zhao M,Wu H,Zhang Y,Lu Q

更新日期：2021-01-07 00:00:00

abstract：:As summarized in Table 1, the literature consistently supports the hypothesis that allergic asthmatic patients have seasonal BHR changes that parallel allergen exposure. These seasonal changes appear to be preventable by treatment with corticosteroids (systemic, inhaled, or nasal), disodium cromoglycate, and immunothe...

journal_title：Clinical reviews in allergy & immunology

authors： Tilles SA,Bardana EJ Jr

更新日期：1997-07-01 00:00:00

abstract：:It has been shown that many hereditary motor neuron diseases are caused by mutation of RNA processing enzymes. Survival of motor neuron 1 (SMN1) is well-known as a causative gene for spinal muscular atrophy (SMA) and mutations of glycyl- and tyrosyl-tRNA synthetases are identified as a cause of distal SMA and Charcot-...

journal_title：Clinical reviews in allergy & immunology

authors： Satoh M,Ceribelli A,Chan EK

更新日期：2012-02-01 00:00:00

abstract：:Skin tests by prick technique offer considerable guidance in the diagnosis of food allergy. Negative prick skin tests are powerful evidence against food allergy. Positive food skin tests are slightly to moderately predictive of reaction to a food on DBPCFC. Oral food challenge is necessary for confirmation of food all...

journal_title：Clinical reviews in allergy & immunology

authors： Williams LW,Bock SA

更新日期：1999-10-01 00:00:00

abstract：:Although allergic asthma was described to be associated with the presence of mucosal T helper (Th)2 cells, it is not entirely clear which factors are responsible for priming of T cells to differentiate into Th2 effector cells in this disease. Interleukin (IL)-6 has been recognized as important because it is secreted b...

journal_title：Clinical reviews in allergy & immunology

authors： Doganci A,Sauer K,Karwot R,Finotto S

更新日期：2005-06-01 00:00:00

abstract：:Tumor necrosis factor-α (TNF-α) is a central regulator of inflammation, and TNF-α antagonists may be effective in treating inflammatory disorders in which TNF-α plays a major pathogenic role. TNF-α has also been associated with inflammatory mechanisms related to implantation, placentation, and pregnancy outcome. TNF-α...

journal_title：Clinical reviews in allergy & immunology

authors： Alijotas-Reig J,Esteve-Valverde E,Ferrer-Oliveras R,Llurba E,Gris JM

更新日期：2017-08-01 00:00:00

abstract：:Patients with primary immunodeficiencies are prone to develop enteropathy of unknown pathogenesis. We hypothesize that ineffective clearance of gastrointestinal pathogens, particularly viruses, in combination with defective immune regulation may cause inflammatory enteropathy in certain immunodeficient hosts. We revie...

journal_title：Clinical reviews in allergy & immunology

authors： van de Ven AA,Hoytema van Konijnenburg DP,Wensing AM,van Montfrans JM

更新日期：2012-02-01 00:00:00

abstract：:Omalizumab is a humanized mouse monoclonal antibody that binds specifically to the constant region of the immunoglobulin (Ig)E heavy chain. Omalizumab exerts its effects by reducing free serum IgE levels and FcepsilonRI expression on several cell types. These effects have been shown to result in decreased airway infla...

journal_title：Clinical reviews in allergy & immunology

authors： Chiang DT,Clark J,Casale TB

更新日期：2005-08-01 00:00:00

abstract：:Acute graft-versus-host disease (GVHD) conceptually may be divided into three evolutionary stages: allostimulation, effector cell homing to specific tissues, and cellular targeting and injury. Surprisingly, little is known regarding the targeting stage of GVHD. Recently, we have learned that epithelial target cell inj...

journal_title：Clinical reviews in allergy & immunology

authors： Murphy GF

更新日期：2007-10-01 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is characterized histologically by the presence of chronic non-suppurative destructive cholangitis of the small interlobular bile duct, leading to chronic progressive cholestasis. Most PBC patients are asymptomatic and have a reasonable prognosis, but a few develop esophageal varices or...

journal_title：Clinical reviews in allergy & immunology

authors： Katsumi T,Tomita K,Leung PS,Yang GX,Gershwin ME,Ueno Y

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The last 5 years have seen the emergence and establishment of antibodies to citrullinated antigens as the diagnostic marker for rheumatoid arthritis (RA). Initially, these were detected using a synthetic peptide, which has undergone a number of modifications to give a diagnostic test with a sensitivity of 65...

journal_title：Clinical reviews in allergy & immunology

authors： Poulsom H,Charles PJ

更新日期：2008-02-01 00:00:00

abstract：:The hyper IgM syndromes are a group of rare inherited immune deficiency disorders characterized by impairment of immunoglobulin isotype switching resulting from defects in the CD40 ligand/CD40 signaling pathway. X-linked forms of hyper IgM are caused by defects in the CD40 ligand gene or NF-κB essential modulator, whi...

journal_title：Clinical reviews in allergy & immunology

authors： Qamar N,Fuleihan RL

更新日期：2014-04-01 00:00:00

abstract：:This review includes a variety of extremely rare and unusual hymenoptera sting (HS) circumstances with regard to sting localization, geographic region, massivity of multiple stings, and particularly related to clinical symptoms. Such reactions occur in a temporal relationship to HS (s), differ from typical allergic sy...

journal_title：Clinical reviews in allergy & immunology

authors： Mingomataj EÇ,Bakiri AH,Ibranji A,Sturm GJ

更新日期：2014-08-01 00:00:00

abstract：:The gold standard for diagnosing asthma in children is based on clinical history of respiratory symptoms, physical examination, and respiratory function testing. Recent advances indicate that a non-invasive measure of airway inflammation, fractional exhaled nitric oxide (FeNO), provides objective data for use in asthm...

journal_title：Clinical reviews in allergy & immunology

authors： Tang S,Xie Y,Yuan C,Sun X,Cui Y

更新日期：2019-04-01 00:00:00

abstract：:Acid anhydrides are used by chemical industries as plasticizers. Trimellitic acid (TMA) is an acid anhydride widely utilized in factories to produce paints, varnishes, and plastics. In addition to causing direct irritant effects, TMA can augment antibody responses in exposed factory workers leading to occupational ast...

journal_title：Clinical reviews in allergy & immunology

authors： Ghosh D,Bernstein JA

更新日期：2020-08-01 00:00:00