A new family with the rare genodermatosis keratosis punctata palmoplantaris Buschke-Fischer-Brauer.

abstract：BACKGROUND:Treatment of chronic discoid lupus erythematosus (CDLE) with a pulsed dye laser (PDL) has shown promising results, although outcomes in previous studies were not validated and laser parameters were inconsistent. OBJECTIVE:We conducted an open prospective study to assess the efficacy and safety of PDL for th...

journal_title：Journal of the American Academy of Dermatology

authors： Erceg A,Bovenschen HJ,van de Kerkhof PC,de Jong EM,Seyger MM

更新日期：2009-04-01 00:00:00

abstract：:An association between HLA-DR1 and the development of multiple basal cell carcinomas was detected in southern Australia. A reduction in HLA-DR4 was found in patients with basal cell carcinoma compared with a local control group. The relative risk for HLA-DR1 was 2.1, which was lower than that for persons in farther co...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Acral vascular syndromes associated with malignancy have rarely been reported. OBJECTIVE:Our purpose was to assess the clinical and evolving features of paraneoplastic acral vascular syndromes. PATIENTS AND METHODS:Two cases of paraneoplastic gangrene are described and analyzed together with previously rep...

journal_title：Journal of the American Academy of Dermatology

authors： Poszepczynska-Guigné E,Viguier M,Chosidow O,Orcel B,Emmerich J,Dubertret L

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The enzyme indoleamine 2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan, and this degradation is an immunosuppressive mechanism that is mainly used by antigen-presenting cells. IDO-expressing dendritic cells and macrophages have previously been identified as components of lymph node granulo...

journal_title：Journal of the American Academy of Dermatology

authors： von Bubnoff D,Scheler M,Wilms H,Wenzel J,von Bubnoff N,Häcker G,Schultze J,Popov A,Racz P,Bieber T,Wickenhauser C

更新日期：2011-10-01 00:00:00

abstract：:Granuloma annulare (GA) represents a cutaneous reaction pattern of unknown cause with a variety of previously described potential disease associations and triggers. This review attempts to synthesize the available data regarding potential etiopathogenesis, reviews the available data on potential GA disease association...

journal_title：Journal of the American Academy of Dermatology

authors： Piette EW,Rosenbach M

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...

journal_title：Journal of the American Academy of Dermatology

authors： Mizukawa Y,Hirahara K,Kano Y,Shiohara T

更新日期：2019-03-01 00:00:00

abstract：:Oral retinoids are among the drugs of choice for pustular and erythrodermic psoriasis. In addition, retinoids are effective in combination with other topical and systemic agents for the treatment of plaque-type psoriasis. Acitretin, the active retinoid metabolite, has replaced etretinate in retinoid therapy of psorias...

journal_title：Journal of the American Academy of Dermatology

authors： Katz HI,Waalen J,Leach EE

更新日期：1999-09-01 00:00:00

abstract：:Isotretinoin is most effective for patients with acne who fail to respond to other forms of treatment; virtually all patients respond to isotretinoin, 0.5 to 1.0 mg/kg/day. As many as 61% of patients are cured after one course, but 39% require further isotretinoin (16%) or oral antibiotics (23%). The relapse rate can ...

journal_title：Journal of the American Academy of Dermatology

authors： Layton AM,Cunliffe WJ

更新日期：1992-12-01 00:00:00

abstract：:Two families with anetoderma are described. Unlike previous reports of familial anetoderma, the disease process seemed to be limited to the skin, and there were no associated ocular, gastrointestinal, or orthopedic anomalies in the affected patients or in any other family members. Although infrequently reported, aneto...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Venencie PY,Bradley RR,Winkelmann RK

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Mycophenolate mofetil (MMF) has enjoyed increasing popularity as an emerging immunosuppressant treatment for various autoimmune dermatologic conditions, including pyoderma gangrenosum (PG). OBJECTIVE:The aim of this study was to examine the efficacy and safety of MMF as used in PG. METHODS:A retrospective ...

journal_title：Journal of the American Academy of Dermatology

authors： Li J,Kelly R

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. OBJECTIVE:We sought to determine the reliability and validity of the MASI. METHODS:After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once d...

journal_title：Journal of the American Academy of Dermatology

authors： Pandya AG,Hynan LS,Bhore R,Riley FC,Guevara IL,Grimes P,Nordlund JJ,Rendon M,Taylor S,Gottschalk RW,Agim NG,Ortonne JP

更新日期：2011-01-01 00:00:00

abstract：:Three patients are described who had a distinctive clinical and histologic presentation of dermal elastosis. Sunlight apparently played little role in the development of this elastotic change. To the best of our knowledge, this is the first report of this form of elastosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Zelickson AS,Padilla RS

更新日期：1989-04-01 00:00:00

abstract：:The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Skelton HG 3rd,Giblin WL,James WD

更新日期：1991-11-01 00:00:00

abstract：:The great diversity of wounds and the broad range of available dressings complicate the selection of proper chronic wound treatment. Choosing the right treatment is the essential step in the healing process. In this review, we focus on chronic nonhealing ulcers, which are a critical problem in clinical practice, and c...

journal_title：Journal of the American Academy of Dermatology

authors： Skórkowska-Telichowska K,Czemplik M,Kulma A,Szopa J

更新日期：2013-04-01 00:00:00

abstract：:Multiple studies have shown that dermoscopy increases the sensitivity and specificity for the detection of skin cancers compared with examination by the naked eye. Dermoscopy can also lead to the detection of thinner and smaller cancers. In addition, dermoscopy leads to the more precise selection of lesions requiring ...

journal_title：Journal of the American Academy of Dermatology

authors： Yélamos O,Braun RP,Liopyris K,Wolner ZJ,Kerl K,Gerami P,Marghoob AA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:In primary melanomas, data on the degree of intratumoral heterogeneity to date have been lacking. OBJECTIVE:Our purpose was to investigate intratumoral DNA stem-line heterogeneity in superficial spreading melanoma (SSM). METHODS:Multiple measuring fields of 54 SSMs (tumor thickness median 1.60 mm) were stu...

journal_title：Journal of the American Academy of Dermatology

authors： Helmbold P,Altrichter D,Klapperstück T,Marsch WCh

更新日期：2005-05-01 00:00:00

abstract：:Atopic dermatitis is a chronic inflammatory skin disease that is frequently associated with respiratory allergies. Atopic dermatitis develops as a result of a complex interrelationship of environmental, immunologic, genetic, and pharmacologic factors. Efforts to understand the relative contributions of these factors h...

journal_title：Journal of the American Academy of Dermatology

authors： Leung DY,Soter NA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Accurate evaluation of basal cell carcinoma (BCC) in the United States was not possible before the 2011 release of BCC-specific International Classification of Diseases, Ninth Revision, Clinical Modification codes. OBJECTIVE:We sought to describe BCC (including locally advanced BCC [LABCC]) incidence/preval...

journal_title：Journal of the American Academy of Dermatology

authors： Goldenberg G,Karagiannis T,Palmer JB,Lotya J,O'Neill C,Kisa R,Herrera V,Siegel DM

更新日期：2016-11-01 00:00:00

abstract：:With increasingly widespread use of cyclosporine for the treatment of psoriasis, it is imperative to identify reliable markers of cyclosporine-induced nephrotoxicity. Five patients with extensive psoriasis and no significant preexisting renal disease were treated with oral cyclosporine (average dosage, 5 mg/kg per day...

journal_title：Journal of the American Academy of Dermatology

authors： Gilbert SC,Emmett M,Menter A,Silverman A,Klintmalm G

更新日期：1989-09-01 00:00:00

abstract：:Patients with HIV and AIDS are living longer because of advancements in antiretroviral therapy. These patients are often susceptible to debilitating inflammatory disorders that are refractory to standard treatment. We discuss the relationship of tumor necrosis factor-alpha and HIV and then review 27 published cases of...

journal_title：Journal of the American Academy of Dermatology

authors： Gallitano SM,McDermott L,Brar K,Lowenstein E

更新日期：2016-05-01 00:00:00

abstract：:Current classifications for hidradenitis suppurativa (HS), such as the Hurley staging system, are not very specific. The absence of rigorous classifications is incongruous with the clinical variability of the condition. There is no pathognomonic sign for HS that leads to a diagnosis that is unquestionable. Consequentl...

journal_title：Journal of the American Academy of Dermatology

authors： van der Zee HH,Jemec GB

更新日期：2015-11-01 00:00:00

abstract：:A combination of topical and oral antifungals is widely used to treat onychomycosis, but treatment failure is common and oral drugs may cause toxicity and potential drug interactions. For this reason, new approaches and strategies should be considered. The following case shows that photodynamic therapy (PDT) may repre...

journal_title：Journal of the American Academy of Dermatology

authors： Piraccini BM,Rech G,Tosti A

更新日期：2008-11-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this first of 5 sections of the guidelines of care for psoriasis, we discuss the classification of psoriasis; associated comorbidities including autoimmune...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Gottlieb A,Feldman SR,Van Voorhees AS,Leonardi CL,Gordon KB,Lebwohl M,Koo JY,Elmets CA,Korman NJ,Beutner KR,Bhushan R

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:In patients with malignancy-associated Sweet syndrome, a thorough evaluation for leukemia cutis should be considered. OBJECTIVE:We sought to describe the clinicopathologic characteristics of histiocytoid Sweet syndrome. METHODS:We retrospectively identified patients with histiocytoid Sweet syndrome at our ...

journal_title：Journal of the American Academy of Dermatology

authors： Chavan RN,Cappel MA,Ketterling RP,Wada DA,Rochet NM,Knudson R,Gibson LE

更新日期：2014-06-01 00:00:00

abstract：:The use of the various forms of phototherapy remains an essential treatment option for psoriasis vulgaris. Expertise concerning the mechanisms involved with the actions of therapeutic ultraviolet light and the proper delivery of office-based treatments resides within the specialty of dermatology. New therapies for the...

journal_title：Journal of the American Academy of Dermatology

authors： Zanolli M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...

journal_title：Journal of the American Academy of Dermatology

authors： Calzavara-Pinton PG,Zane C,Carlino A,De Panfilis G

更新日期：1997-06-01 00:00:00

abstract：:Transillumination with a high-intensity fiberoptic light source is an effective means of diagnosing pneumothoraces and localizing arteries and veins for blood sampling. It has been used for these purposes in neonatal intensive care units since the 1970s. Thermal burns were reported in association with the technique in...

journal_title：Journal of the American Academy of Dermatology

authors： Sajben FP,Gibbs NF,Friedlander SF

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Psoriasis is a systemic inflammatory condition that is associated with a higher risk of cardiovascular (CV) disease. Tofacitinib is being investigated as a treatment for psoriasis. OBJECTIVE:We sought to evaluate the effects of tofacitinib on CV risk factors and major adverse CV events (MACEs) in patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Wu JJ,Strober BE,Hansen PR,Ahlehoff O,Egeberg A,Qureshi AA,Robertson D,Valdez H,Tan H,Wolk R

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Current knowledge of angiolymphoid hyperplasia with eosinophilia (ALHE) derives from retrospective reports and case series, leading to a nonevidence-based treatment approach. OBJECTIVE:We sought to systematically review the literature relating to cutaneous ALHE to estimate its epidemiology and treatment out...

journal_title：Journal of the American Academy of Dermatology

authors： Adler BL,Krausz AE,Minuti A,Silverberg JI,Lev-Tov H

更新日期：2016-03-01 00:00:00

abstract：:Because Of Increasing Concern With The Ethical Challenges To Physicians In Recent Years, A Committee Of The Council Of Medical Specialty Societies (CMSS), Under The Chairmanship Of Sara C. Charles, Md, Organized A 2-DAY Symposium On The Ethic Of Medicine In April 1997. During This Conference 6 Workgroup Sessions Were ...

journal_title：Journal of the American Academy of Dermatology

authors： Sams WM

更新日期：2000-01-01 00:00:00