Position sense at the proximal interphalangeal joint is distorted in patients with rheumatoid arthritis of finger joints.

abstract：:Arterial pressure is regulated over long periods of time by neural, hormonal and local control mechanisms, which ultimately determine the total blood volume and how it is distributed between the various vascular compartments of the circulation. A full understanding of the complex interplay of these mechanisms can be g...

journal_title：Experimental physiology

authors： Osborn JW,Averina VA,Fink GD

更新日期：2009-04-01 00:00:00

abstract：:Intestinal secretion is enhanced by starvation in rats. The rectum from fed and 3-day-starved rats generates a basal electrogenic ion transfer (short-circuit current) in vitro which is mainly electrogenic Na+ absorption (amiloride-sensitive, 66-71%) with a small component of electrogenic chloride secretion (furosemide...

journal_title：Experimental physiology

authors： Levin RJ,Parker AJ

更新日期：1990-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Are the urinary concentrations of NO and ATP, and their metabolites, associated with the severity of symptoms of overactive bladder? What is the main finding and its importance? The urinary ratios of [ATP/NO], [ADP/NO] and a combination of these, [ATP/Cr*ADP/Cr]/...

journal_title：Experimental physiology

authors： Firouzmand S,Young JS

更新日期：2020-06-01 00:00:00

abstract：:One of the most basic computational elements within a circuit is the synapse across which signals are transferred. Here we summarize some experimental strategies that allow the synaptic basis of circuit function to be studied through imaging. The two most promising approaches available currently are pHluorin-based rep...

journal_title：Experimental physiology

authors： Dreosti E,Lagnado L

更新日期：2011-01-01 00:00:00

abstract：:Recent studies showed that progesterone stimulates the hypoxic ventilatory response and may reduce apnoea frequency in newborn rats, but so far we still do not know by what mechanisms and whether endogenous progesterone might contribute to respiratory control in neonates. We therefore determined the role of the nuclea...

journal_title：Experimental physiology

authors： Potvin C,Rossignol O,Uppari N,Dallongeville A,Bairam A,Joseph V

更新日期：2014-11-01 00:00:00

abstract：:Sympathetic baroreflex sensitivity is increased during selective activation of the skeletal muscle metaboreflex with postexercise ischaemia (PEI) in young adults. However, to date, there are no data demonstrating this neural interaction between the arterial baroreflex and the muscle metaboreflex in healthy older adult...

journal_title：Experimental physiology

authors： Greaney JL,Schwartz CE,Edwards DG,Fadel PJ,Farquhar WB

更新日期：2013-10-01 00:00:00

abstract：:Luminal fluids were collected in vivo by micropuncture and cannulation from the rete testis, efferent ducts and ductus epididymidis of the rat to determine the composition of efferent duct fluids and the rates of reabsorption of water and solutes by the efferent ducts. The concentration of spermatozoa increased by a f...

journal_title：Experimental physiology

authors： Clulow J,Jones RC,Hansen LA

更新日期：1994-11-01 00:00:00

abstract：:In mammals, including man, epidemiological and experimental studies have shown that a range of environmental factors acting during critical periods of early development can alter adult phenotype. Hormones have an important role in these epigenetic modifications and can signal the type, severity and duration of the env...

journal_title：Experimental physiology

authors： Fowden AL,Forhead AJ

更新日期：2009-06-01 00:00:00

abstract：:Lateral ventricular volumes were monitored and quantified using accurately registered magnetic resonance images (MRIs) in six healthy individuals 30 min before and up to 4 h after ingestion of a glucose drink. The volume of the lateral ventricles increased by an average (+/- S.E.M.) of 2.4 +/- 0.4% as blood glucose le...

journal_title：Experimental physiology

authors： Puri BK,Lewis HJ,Saeed N,Davey NJ

更新日期：1999-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? We present a new non-invasive medical technology, the inspired sine-wave technique, which involves inhalation of sinusoidally fluctuating concentrations of a tracer gas. The technique requires only passive patient cooperation and can monitor different cardiorespi...

journal_title：Experimental physiology

authors： Bruce RM,Phan PA,Pacpaco E,Rahman NM,Farmery AD

更新日期：2018-05-01 00:00:00

abstract：:A method is described that enables the cell membrane of isolated rat ventricular myocytes to be permeabilized and resealed while maintaining cell viability. Streptolysin O, a cholesterol-binding cytolysin, was used to form pores in the surface membrane; subsequent incubation with 5% fetal bovine serum was used to reve...

journal_title：Experimental physiology

authors： Fawcett JM,Harrison SM,Orchard CH

更新日期：1998-05-01 00:00:00

abstract：:Simultaneous portal blood absorption and intestinal mucosal catabolism of labelled fatty acids were investigated. Anaesthetized adult Wistar rats were infused intraduodenally either with 90 mumol of capric (C10:0), oleic (C18:1), linoleic (C18:2) or arachidonic (C20:4) 1-14C acids or with 30 mumol of each labelled fat...

journal_title：Experimental physiology

authors： Bernard A,Carlier H

更新日期：1991-05-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? I focus on clinical aspects of uterine physiology, specifically, myometrial contractility. I bring together and contrast findings using physiological approaches and those using newer techniques, 'omics'. What advances does it highlight? Physiological studies have recently ...

journal_title：Experimental physiology

authors： Wray S

更新日期：2015-12-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Glucose is the dominant energy source for the brain. However, little is known about how glucose metabolism impacts the coordination of network activity in the brain in healthy adults. What is the main finding and its importance? We demonstrate that both alpha osc...

journal_title：Experimental physiology

authors： Walker CP,Buse J,Frohlich F

更新日期：2021-01-28 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What are the characteristics of the NK cell response following acute moderate-intensity aerobic exercise in prostate cancer survivors and is there a relationship between stress hormones and NK cell mobilization? What is the main finding and its importance? NK cel...

journal_title：Experimental physiology

authors： Hanson ED,Sakkal S,Que S,Cho E,Spielmann G,Kadife E,Violet JA,Battaglini CL,Stoner L,Bartlett DB,McConell GK,Hayes A

更新日期：2020-09-01 00:00:00

abstract：:The pathogenesis of the vasodilatation associated with liver cirrhosis is not fully understood, but it has recently been postulated that it may be related to an increase in nitric oxide production. The aim of this study was to compare the response of isolated aortic rings from normal and cirrhotic rats to two vasocons...

journal_title：Experimental physiology

authors： Van Obbergh L,Leonard V,Chen H,Xu D,Blaise G

更新日期：1995-07-01 00:00:00

abstract：:The role of endothelium in the decreased contraction to phenylephrine in aorta of pregnant Wistar rats has been studied. Contractions in response to phenylephrine were significantly decreased in aortic rings from pregnant rats compared to those from non-pregnant rats. Pretreatment of the rings with indomethacin did no...

journal_title：Experimental physiology

authors： Aloamaka CP,Ezimokhai M,Cherian T,Morrison J

更新日期：1993-05-01 00:00:00

abstract：:A global and transient rise of intracellular Ca2+ (Ca2+i) is central to the operation of pump-leak coupling in the frog early distal tubule (EDT). The endoplasmic reticulum (ER) is the site of this Ca2+ release and reuptake; however, it is likely that other intracellular pools, such as mitochondria, also contribute to...

journal_title：Experimental physiology

authors： Fowler MR,Hunter M

更新日期：2005-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Is electrical pulse stimulation (EPS) an in vitro exercise model able to elicit the hypertrophy of human muscle cells? What is the main finding and its importance? The addition of a restitution period of 8 h after EPS induces the enlargement of human muscle cells...

journal_title：Experimental physiology

authors： Tarum J,Folkesson M,Atherton PJ,Kadi F

更新日期：2017-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Hypoxic pulmonary vasoconstriction has never been characterized in isolated mouse pulmonary arteries of different generations in detail. What is the main finding and its importance? We found that only small intrapulmonary arteries (80-200 μm in diameter) exhibit ...

journal_title：Experimental physiology

authors： Strielkov I,Krause NC,Sommer N,Schermuly RT,Ghofrani HA,Grimminger F,Gudermann T,Dietrich A,Weissmann N

更新日期：2018-09-01 00:00:00

abstract：:Obstructive sleep apnoea (OSA) leads to chronic intermittent hypoxia (CIH) during sleep. Obstructive sleep apnoea has been associated with liver injury. Acetaminophen (APAP; known as paracetamol outside the USA) is one of the most commonly used drugs which has known hepatotoxicity. The goal of the present study was to...

journal_title：Experimental physiology

authors： Savransky V,Reinke C,Jun J,Bevans-Fonti S,Nanayakkara A,Li J,Myers AC,Torbenson MS,Polotsky VY

更新日期：2009-02-01 00:00:00

abstract：:The present study investigated the absolute reliability (R(Ab)) of isometric measures of time-to-peak tension (TTP), half-rise time ((1/2)RT), half-fall time ((1/2)FT), twitch force (TW(f)) tetanic force (TET(f)) and the sag ratio as applied to the slow soleus (SOL) and the fast-twitch extensor digitorum longus (EDL) ...

journal_title：Experimental physiology

authors： Gallo M,Gordon T,Tyreman N,Shu Y,Putman CT

更新日期：2004-09-01 00:00:00

abstract：:Noxious somatic stimulation evokes respiratory and autonomic responses. The mechanisms underlying the responses and the manner in which they are co-ordinated are still unclear. The effects of activation of somatic nociceptive fibres on lumbar sympathetic nerve activity at slow (2-10 Hz) and fast frequency bands (100-1...

journal_title：Experimental physiology

authors： Korim WS,Egwuenu E,Fong AY,McMullan S,Cravo SL,Pilowsky PM

更新日期：2012-10-01 00:00:00

abstract：:In vivo microperfusion techniques were used to investigate the role of Na+-H+ exchange in the efferent ducts of the rat. Individual efferent ducts were perfused with a Krebs-Ringer bicarbonate solution (KRB) containing 0, 1, 3, 5 or 7.5 mM amiloride. Concentrations of 1-5 mM amiloride inhibited fluid reabsorption from...

journal_title：Experimental physiology

authors： Hansen LA,Clulow J,Jones RC

更新日期：1999-05-01 00:00:00

abstract：:The endothelial glycocalyx layer of capillaries was stained with Ruthenium Red and examined by transmission electron microscopy in rat extensor hallucis proprius muscles after 2 or 4 days of indirect electrical stimulation via implanted electrodes. The layer appeared continuous on the luminal surface of 63% capillarie...

journal_title：Experimental physiology

authors： Brown MD,Egginton S,Hudlicka O,Zhou AL

更新日期：1996-11-01 00:00:00

abstract：:The glucagon response to insulin-induced hypoglycaemia was tested in rats that had been pinealectomised (Px), pinealectomised and fitted with melatonin implants (Px + MLT), or sham-operated (SO). The glucagon response to hypoglycaemia observed in SO rats (216 +/- 27 pg x ml(-1) at baseline versus 397 +/- 35 pg x ml(-1...

journal_title：Experimental physiology

authors： Kosa E,Maurel D,Siaud P

更新日期：2001-09-01 00:00:00

abstract：:Ageing is associated with skeletal muscle impairment. Changes in mitochondrial homeostasis are thought to play a key role in this process. This study examined whether chronic intake of polyphenols (PPs), which are known to be modulators of oxidative stress, might prevent the age-related decline of mitochondrial functi...

journal_title：Experimental physiology

authors： Charles AL,Meyer A,Dal-Ros S,Auger C,Keller N,Ramamoorthy TG,Zoll J,Metzger D,Schini-Kerth V,Geny B

更新日期：2013-02-01 00:00:00

abstract：:Hypoxia has been reported to increase arterial potassium concentration ([K+]a) in anaesthetized cats (Paterson, Estavillo & Nye, 1988). The purpose of this study was to determine whether this phenomenon occurs in humans. The effect of hypoxia on [K+]a was measured in ten male subjects, at rest and during light exercis...

journal_title：Experimental physiology

authors： Barlow CW,Qayyum MS,Davey PP,Paterson DJ,Robbins PA

更新日期：1994-03-01 00:00:00

abstract：:In anaesthetized cats, reflex respiratory responses were evoked by electrically stimulating proximal ends of cut nerves to gastrocnemius-soleus muscles of the left hindlimb. The direction of these responses, in the excitatory or inhibitory sense, depended on the types of afferent fibres stimulated and on the mode of s...

journal_title：Experimental physiology

authors： Decandia M,Orani GP

更新日期：1995-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? We sought to understand the day-to-day variability of human indirect calorimetry during rest and exercise. Previous work has been unable to separate human day-to-day variability from measurement error and within-trial human variability. We developed models accoun...

journal_title：Experimental physiology

authors： Tenan MS,Bohannon AW,Macfarlane DJ,Crouter SE

更新日期：2018-12-01 00:00:00