Abstract:
:The glucagon response to insulin-induced hypoglycaemia was tested in rats that had been pinealectomised (Px), pinealectomised and fitted with melatonin implants (Px + MLT), or sham-operated (SO). The glucagon response to hypoglycaemia observed in SO rats (216 +/- 27 pg x ml(-1) at baseline versus 397 +/- 35 pg x ml(-1) at the hypoglycaemic peak, mean +/- S.D.) was stronger than that in Px rats (180 +/- 37 pg x ml(-1) and 229 +/- 21 pg x ml(-1), respectively) and weaker than that in Px + MLT rats (256 +/- 19 pg x ml(-1) and 516 +/- 11 pg x ml(-1), respectively). Our data indicate that the capacity to release glucagon during insulin-induced hypoglycaemia is altered in pinealectomised rats.
journal_name
Exp Physioljournal_title
Experimental physiologyauthors
Kosa E,Maurel D,Siaud Pdoi
10.1113/eph8602205subject
Has Abstractpub_date
2001-09-01 00:00:00pages
617-20issue
5eissn
0958-0670issn
1469-445Xpii
EPH_2205journal_volume
86pub_type
杂志文章abstract::Embryonic stem (ES) cells are pluripotent cells isolated from the inner cell mass of blastocysts. ES cells are able to differentiate into the three primitive layers (endoderm, mesoderm and ectoderm) of the organism, including the germline. To study early stages of development, as well as to investigate the impact of a...
journal_title:Experimental physiology
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doi:
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journal_title:Experimental physiology
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journal_title:Experimental physiology
pub_type: 杂志文章,评审
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journal_title:Experimental physiology
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更新日期:2017-11-01 00:00:00
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journal_title:Experimental physiology
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journal_title:Experimental physiology
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更新日期:2015-04-20 00:00:00
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