Volumetric change of the lateral ventricles in the human brain following glucose loading.

abstract：:We have considered the manner in which data obtained with ion-selective electrodes should be evaluated. The potential difference recorded by such electrodes, with respect to a stable reference, is converted to a concentration by a non-linear transformation--the Nernst or Nikolsky equation. The mean and standard deviat...

journal_title：Experimental physiology

authors： Fry CH,Hall SK,Blatter LA,McGuigan JA

更新日期：1990-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Exertional heat stroke is accompanied by a marked inflammatory response. In this study, we explored the time course of acute phase proteins during recovery from severe heat stress in mice and the potential role of skeletal muscles as their source. What is the mai...

journal_title：Experimental physiology

authors： Iwaniec J,Robinson GP,Garcia CK,Murray KO,de Carvalho L,Clanton TL,Laitano O

更新日期：2021-01-01 00:00:00

abstract：:The intrinsic proton buffering power (beta 1) of individual rat hippocampal and neocortical neurones maintained in culture has been investigated using the fluorescent dye 2', 7'-bis(carboxymethyl)-5, 6-(carboxyfluorescein) (BCECF). The steady-state intracellular pH (pH1) was estimated to be 7.03 +/- 0.04 (n = 22) in H...

journal_title：Experimental physiology

authors： Amos BJ,Richards CD

更新日期：1996-03-01 00:00:00

abstract：:Transport of a number of dipolar amino acids (and the orally active antibiotic D-cycloserine) across the apical membrane of human intestinal epithelial (Caco-2) cell monolayers is mediated by a Na+-independent, pH-dependent transport mechanism. Relatively little is known about the mode of action of this transport syst...

journal_title：Experimental physiology

authors： Thwaites DT,Stevens BC

更新日期：1999-03-01 00:00:00

abstract：UNLABELLED:The modulation of activity of the upper airway dilator and respiratory muscles plays a key role in the regulation of ventilation, but little is known about the link between their neuromuscular activation processes in vivo. This study investigated genioglossus and diaphragm responses to transcranial magnetic ...

journal_title：Experimental physiology

authors： Wang W,Similowski T,Sériès F

更新日期：2007-07-01 00:00:00

abstract：:The effect of the neuronal 5-HT3 receptor antagonist MDL 72222 has been investigated on the reflex tachypnoeic response to pulmonary embolism in pentobarbitone-anaesthetized rabbits. Pre-treatment with MDL 72222 (640 micrograms kg-1, 5 min prior to embolization) significantly attenuated the reflex tachypnoeic response...

journal_title：Experimental physiology

authors： Armstrong DJ,Kay IS

更新日期：1990-07-01 00:00:00

abstract：:Flow of submandibular saliva and the constituents secreted during chorda-lingual nerve stimulation at 40 Hz (3 x 10 min) were studied after alpha- and beta-adrenergic blockade, and in the absence (control) or presence of cholinergic blockade in anaesthetized rats. Peroxidase and true tissue kallikrein (rK1) were asses...

journal_title：Experimental physiology

authors： Garrett JR,Anderson LC,Zhang XS,Proctor GB

更新日期：1996-05-01 00:00:00

abstract：:We have examined the surface ultrastructure and morphological characteristics of leucocytes obtained from control rats breathing air and rats made acutely hypoxic (breathing 6% O2, for 30 min). Striking ultrastructural and morphological changes occurred in the leucocytes of hypoxic rats. These changes included the app...

journal_title：Experimental physiology

authors： Mian R,Westwood D,Stanley P,Marshall JM,Coote JH

更新日期：1993-11-01 00:00:00

abstract：:The cardiovascular response to isometric exercise is governed by both central and peripheral mechanisms. Both metabolic and mechanical stresses on the exercising skeletal muscle produce cardiovascular change, yet it is often overlooked that the afferent signal arising from the muscle can be modified by factors other t...

journal_title：Experimental physiology

authors： Fisher JP,White MJ

更新日期：2004-11-01 00:00:00

abstract：:Gastric distension in anaesthetized pigs reflexly elicits peripheral vasoconstriction and an increase in plasma renin activity (PRA), with vagal afferent and sympathetic efferent limbs. The aim of the present study was to quantify the contribution of the renin-angiotensin system to the peripheral vasoconstriction. In ...

journal_title：Experimental physiology

authors： Molinari C,Battaglia A,Grossini E,Florio S,Mary DA,Vassanelli C,Vacca G

更新日期：2003-05-01 00:00:00

abstract：:The hypothalamus regulates the key hormonal signalling events essential for reproduction and fertility in mammals. The gonadotrophin-releasing hormone (GnRH) neurons are the principal neurons of the complex neuronal network that co-ordinates multiple internal homeostatic and external factors necessary for fertility. K...

journal_title：Experimental physiology

authors： Yeo SH

更新日期：2013-11-01 00:00:00

abstract：:An investigation was made of the effects of H1 and H2 receptor agonists and antagonists on rabbit pancreatic exocrine secretion stimulated by secretin and cholecystokinin (CCK). The H1 agonist 2-thiazolylethylamine elicited dose-dependent increases in the rate of secretion. Increases in pancreatic juice flow and enzym...

journal_title：Experimental physiology

authors： Pariente JA,Madrid JA,Salido GM

更新日期：1990-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Is electrical pulse stimulation (EPS) an in vitro exercise model able to elicit the hypertrophy of human muscle cells? What is the main finding and its importance? The addition of a restitution period of 8 h after EPS induces the enlargement of human muscle cells...

journal_title：Experimental physiology

authors： Tarum J,Folkesson M,Atherton PJ,Kadi F

更新日期：2017-11-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Compared with Caucasians, African individuals are more susceptible to non-freezing cold injury and experience greater cutaneous vasoconstriction and cooler finger skin temperatures upon hand cooling. We investigated whether the enzyme cyclooxygenase is, in part, ...

journal_title：Experimental physiology

authors： Maley MJ,House JR,Tipton MJ,Eglin CM

更新日期：2017-07-01 00:00:00

abstract：:The uptake and distribution of CO throughout the circulatory system during two different methods of CO rebreathing (2 min 'Schmidt' and 40 min 'Burge' methods) were determined in nine healthy volunteers. Specifically, the impact of (i) differences in circulatory mixing time (t(mix)), (ii) CO diffusion to myoglobin (Mb...

journal_title：Experimental physiology

authors： Garvican LA,Burge CM,Cox AJ,Clark SA,Martin DT,Gore CJ

更新日期：2010-12-01 00:00:00

abstract：:The autonomic adjustments to exercise are mediated by central signals from the higher brain (central command) and by a peripheral reflex arising from working skeletal muscle (exercise pressor reflex), with further modulation provided by the arterial baroreflex. Although it is clear that central command, the exercise p...

journal_title：Experimental physiology

authors： Williamson JW,Fadel PJ,Mitchell JH

更新日期：2006-01-01 00:00:00

abstract：:What is the central question of this study? Failure to terminate apnoea and arouse is likely to contribute to sudden infant death syndrome (SIDS). Serotonin is deficient in the brainstems of babies who died of SIDS. Therefore, we tested the hypothesis that serotonin in the nucleus of the solitary tract (NTS) would sho...

journal_title：Experimental physiology

authors： Donnelly WT,Bartlett D Jr,Leiter JC

更新日期：2016-07-01 00:00:00

abstract：:Hypertension caused by chronic infusion of angiotensin II (Ang II) in experimental animals is dependent, in part, on increased activity of the sympathetic nervous system. This chronic sympathoexcitatory response is amplified by a high-salt diet, suggesting an interaction of circulating Ang II and dietary salt on sympa...

journal_title：Experimental physiology

authors： Osborn JW,Hendel MD,Collister JP,Ariza-Guzman PA,Fink GD

更新日期：2012-01-01 00:00:00

abstract：:The objective of the experiments was to investigate the cellular basis of the inotropic effect on myocardium of several opioids which have been implicated in producing cardiotoxic effects in human poisoning. Opioids exerted negative inotropic effects, with half-maximal concentrations between 10 microM (dextropropoxyph...

journal_title：Experimental physiology

authors： Wu C,Fry CH,Henry J

更新日期：1997-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? There is an ethical imperative to optimize analgesia protocols for laboratory animals, but this is impeded by our inability to recognize pain reliably. We examined whether the Mouse Grimace Scale (MGS) provides benefits over a standard welfare scoring system for ...

journal_title：Experimental physiology

authors： Faller KM,McAndrew DJ,Schneider JE,Lygate CA

更新日期：2015-02-01 00:00:00

abstract：:We have examined the effect of a hyposmotic shock, and thus cell swelling, upon the efflux of amino acids, SO4(2-) and I- from lactating mammary tissue. A hyposmotic challenge increased the efflux of taurine and glycine via a 4,4'-diisothiocyanatostilbene-2,2'- disulphonic acid (DIDS)-sensitive pathway. It appears tha...

journal_title：Experimental physiology

authors： Shennan DB,McNeillie SA,Curran DE

更新日期：1994-09-01 00:00:00

abstract：:The effects of microinjections of adenosine and an adenosine receptor antagonist into the rostral ventrolateral medulla (RVLM) on the cardiovascular changes associated with the defence reaction were investigated in anaesthetized rats. Responses to electrical and chemical stimulation in RVLM were determined in alpha-ch...

journal_title：Experimental physiology

authors： Thomas T,Spyer KM

更新日期：1996-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? In fever, the most striking response in the acute phase reaction of systemic inflammation, plasma H2 S concentration increases. However, the role of endogenous peripheral H2 S in fever is unknown. What is the main finding and its importance? Endogenous peripheral...

journal_title：Experimental physiology

authors： Soriano RN,Braga SP,Breder JSC,Batalhao ME,Oliveira-Pelegrin GR,Ferreira LFR,Rocha MJA,Carnio EC,Branco LGS

更新日期：2018-03-01 00:00:00

abstract：:The effects of two different feeding regimes on the 24 h profiles of maternal and fetal plasma cortisol and adrenocorticotrophic hormone (ACTH) concentrations were studied in eight pregnant ewes between 123 and 144 days of gestation. Once daily-fed ewes (n = 4) received 1 kg of lucerne-chaff at 11.00 h, and multi-fed ...

journal_title：Experimental physiology

authors： Simonetta G,Walker DW,McMillen IC

更新日期：1991-03-01 00:00:00

abstract：:Intestinal secretion is enhanced by starvation in rats. The rectum from fed and 3-day-starved rats generates a basal electrogenic ion transfer (short-circuit current) in vitro which is mainly electrogenic Na+ absorption (amiloride-sensitive, 66-71%) with a small component of electrogenic chloride secretion (furosemide...

journal_title：Experimental physiology

authors： Levin RJ,Parker AJ

更新日期：1990-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What factors influence the onset and magnitude of activation of the neck inspiratory muscles during inspiration? What is the main finding and its importance? Recruitment of the sternocleidomastoid and scalene muscles during inspiration, measured by means of surfa...

journal_title：Experimental physiology

authors： Washino S,Mankyu H,Kanehisa H,Mayfield DL,Cresswell AG,Yoshitake Y

更新日期：2019-04-01 00:00:00

abstract：:We recently reported that a higher percentage of type I fibres in vastus lateralis and a greater peak oxygen uptake (O2) were associated with a greater initial rise in O2 (O2 /W, where W is work rate) following the onset of heavy constant power output exercise (above the lactate threshold, LT). It was unclear if these...

journal_title：Experimental physiology

authors： Barstow TJ,Jones AM,Nguyen PH,Casaburi R

更新日期：2000-01-01 00:00:00

abstract：:We tested the hypothesis that, among conditions of matched contractile work, shorter contraction durations and greater muscle fibre recruitment result in augmented skeletal muscle blood flow and oxygen consumption ( ) during steady-state exercise in humans. To do so, we measured forearm blood flow (FBF; Doppler ultras...

journal_title：Experimental physiology

authors： Richards JC,Crecelius AR,Kirby BS,Larson DG,Dinenno FA

更新日期：2012-06-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Can low-dose inorganic nitrate supplementation prevent testicular structural and functional alterations in streptozotocin-induced type 1 diabetic male rats? What is the main finding and it's important? Treatment with a low dose of inorganic nitrate for 2 months h...

journal_title：Experimental physiology

authors： Oghbaei H,Alipour MR,Hamidian G,Ahmadi M,Ghorbanzadeh V,Keyhanmanesh R

更新日期：2018-12-01 00:00:00

abstract：:In pentobarbitione-anaesthetized rats the parasympathetic auriculotemporal nerve of the parotid gland was continuously stimulated at supramaximal voltage and at maximal frequency (40 Hz) for salivary secretion. The animals were pretreated with phentolamine and propranolol (2 mg kg-1 i.p. of each) and, in some groups, ...

journal_title：Experimental physiology

authors： Ekström J,Asztély A,Tobin G

更新日期：1996-11-01 00:00:00