Effect of hypoxia on arterial potassium concentration at rest and during exercise in man.

abstract：:A stress protocol--6 h of daily immobilization--was applied throughout male rat sexual development. Immobilization caused a small reduction in food intake and body weight gain whereas pair-fed animals had a marginal decrease only in body weight gain. Stress, confirmed by increased plasma adrenocorticotrophic hormone (...

journal_title：Experimental physiology

authors： Almeida SA,Anselmo-Franci JA,Rosa e Silva AA,Carvalho TL

更新日期：1998-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? The central goal of this study was to elucidate the role of magnesium in the regulation of pulmonary vascular reactivity in relationship to hypoxic pulmonary hypertension. What is the main finding and its importance? We found that magnesium is essential for norma...

journal_title：Experimental physiology

authors： Mu YP,Huang QH,Zhu JL,Zheng SY,Yan FR,Zhuang XL,Sham JSK,Lin MJ

更新日期：2018-04-01 00:00:00

abstract：:In quiescent papillary muscles isolated from hearts of rats with streptozotocin-induced diabetes resting intracellular sodium activity (aiNa) was about 56% greater than in muscles from controls. An intracellular acid load induced by the NH4+ method caused a rise in aiNa whose maximum amplitude was similar in both grou...

journal_title：Experimental physiology

authors： Lagadic-Gossmann D,Feuvray D

更新日期：1991-01-01 00:00:00

abstract：:Although numerous studies have recently implicated the calcineurin-nuclear factor of activated T-cells (Cn-NFAT) signalling pathway in the regulation of activity-dependent fibre type switching in adult mammalian skeletal muscles, little is known about the endogenous expression of NFAT proteins in the various fibre typ...

journal_title：Experimental physiology

authors： Mutungi G

更新日期：2008-03-01 00:00:00

abstract：:It is unknown whether changes in corticomotor excitability follow prolonged exercise in healthy humans. Furthermore, the role of supraspinal fatigue in decrements of force production and voluntary activation following prolonged exercise has not been established. This study investigated peripheral and central fatigue a...

journal_title：Experimental physiology

authors： Ross EZ,Middleton N,Shave R,George K,Nowicky A

更新日期：2007-03-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Are the urinary concentrations of NO and ATP, and their metabolites, associated with the severity of symptoms of overactive bladder? What is the main finding and its importance? The urinary ratios of [ATP/NO], [ADP/NO] and a combination of these, [ATP/Cr*ADP/Cr]/...

journal_title：Experimental physiology

authors： Firouzmand S,Young JS

更新日期：2020-06-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What mechanisms account for the hypotension observed during chronic elevations in circulating 5-hydroxytryptamine in rats? What is the main finding and its importance? Chronic 5-hydroxytryptamine-induced hypotension requires continued activation of the 5-HT7 rece...

journal_title：Experimental physiology

authors： Seitz BM,Fink GD,Watts SW

更新日期：2020-10-14 00:00:00

abstract：:Mechanical properties of the vascular smooth muscle from normal and dystrophin-deficient (mdx) mice were examined. Changes in resting and developed tensions in response to stretch were recorded in isolated portal vein. The vascular segments were elongated in 5 % increments of the 'in situ' length (Lr) up to 1.30Lr. Th...

journal_title：Experimental physiology

authors： Mancinelli R,Tonali P,Romani R,Tringali A,Vargiu R,AZZENA GB

更新日期：1999-09-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? The central question of this study was to investigate the interaction of mild exposures to O2 and CO2 on chemoreflex control of SNA and the modulation of lung volume and respiratory phase on this interaction. What is the main finding and its importance? We demons...

journal_title：Experimental physiology

authors： Jouett NP,Watenpaugh DE,Dunlap ME,Smith ML

更新日期：2015-09-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This review is principally concerned with results from studies of the pulmonary vasculature in humans, particularly in relation to hypoxia and rare diseases that affect oxygen sensing. What advances does it highlight? This review highlights the degree to which the hypoxia-...

journal_title：Experimental physiology

authors： Frise MC,Robbins PA

更新日期：2015-11-01 00:00:00

abstract：:The present study was designed to investigate the renal responses to hypotensive haemorrhage early in life and the role of renal sympathetic nerves in modulating these renal responses. To this end, experiments were carried out in conscious, chronically instrumented lambs with either intact renal nerves (n = 7, Intact)...

journal_title：Experimental physiology

authors： Smith FG

更新日期：2002-09-01 00:00:00

abstract：:The dorsal horn of the spinal cord plays an important role in transmitting information from nociceptive primary afferent neurones to the brain; however, our knowledge of its neuronal and synaptic organisation is still limited. Nociceptive afferents terminate mainly in laminae I and II and some of these contain substan...

journal_title：Experimental physiology

authors： Todd AJ

更新日期：2002-03-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? One of the major unanswered questions in physiology is that of how breathing matches metabolic rate. Venous chemoreceptors seem to have been dismissed since the 1960s. What advances does it highlight? New evidence shows that their apparent dismissal needs reappraisal. The ...

journal_title：Experimental physiology

authors： Parkes MJ

更新日期：2017-12-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Do GABA receptors play any role at the neuromuscular junction? What is the main finding and its importance? In the presence of either ionotropic or metabotropic GABA receptor antagonists, diaphragm muscle force production elicited by stimulating the motor nerve a...

journal_title：Experimental physiology

authors： Lenina O,Petrov K,Kovyazina I,Malomouzh A

更新日期：2019-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? What is the carotid bodies' contribution to active inspiratory and expiratory response to exercise? What is the main finding and its importance? Removal of the carotid bodies reduced the active inspiratory and expiratory responses of diaphragm and abdominal inter...

journal_title：Experimental physiology

authors： Spiller PF,da Silva CAA,Francescato HDC,Moraes DJA

更新日期：2020-08-01 00:00:00

abstract：:The effects of direct autonomic nerve stimulation on the heart may be quite different to those of perfusion with pharmacological neuromodulating agents. This study was designed to investigate the effect of autonomic nerve stimulation on intracellular calcium fluorescence using fura-2 AM in the isolated Langendorff-per...

journal_title：Experimental physiology

authors： Brack KE,Coote JH,Ng GA

更新日期：2010-01-01 00:00:00

abstract：:In the present study, the ontogenic changes in gluconeogenic enzyme activities and in hepatic glycogen and beta-adrenergic receptor levels were investigated in fetal pigs from 70 days of gestation until delivery at term (114 +/- 2 days). The values were compared with those observed in fetuses infused subcutaneously wi...

journal_title：Experimental physiology

authors： Fowden AL,Apatu RS,Silver M

更新日期：1995-05-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Is an anti-oedematous effect of ghrelin associated with increased expression of tight junction proteins in the hypoxic brain? What is the main finding and its importance? We showed that injection of ghrelin during acute and chronic systemic hypoxia is associated ...

journal_title：Experimental physiology

authors： Mohaddes G,Abdolalizadeh J,Babri S,Hossienzadeh F

更新日期：2017-03-01 00:00:00

abstract：:The study examined the effect of salt-induced hypertension on vascular relaxation in response to magnesium sulphate during pregnancy. Pregnant Wistar rats were fed for 6 weeks on a diet containing 0.3% (control) and 8.0% (test) sodium chloride. Aortic rings were then removed and contracted with 10(-7) M phenylephrine ...

journal_title：Experimental physiology

authors： Aloamaka CP,Ezimokhai M,Osman NA,Morrison J

更新日期：1995-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Impairment and subsequent improvement in cerebral oxygenation during acute and prolonged exposure to high altitude affect exercise performance. This study innovates by investigating the effect of acute and prolonged high-altitude exposure on cerebral haemodynamic...

journal_title：Experimental physiology

authors： Marillier M,Rupp T,Bouzat P,Walther G,Baillieul S,Millet GY,Robach P,Verges S

更新日期：2021-01-01 00:00:00

abstract：:Plasma osteocalcin, or plasma bone GLA protein (BGP), total plasma alkaline phosphatase activity and urinary hydroxyproline excretion of twenty-four pregnant dairy cows (thirteen in their first or second pregnancy, i.e. low parity, and eleven in their third or more pregnancies, i.e. high parity) were measured from 7 w...

journal_title：Experimental physiology

authors： van Mosel M,Corlett SC

更新日期：1990-11-01 00:00:00

abstract：:We hypothesized that exercise performance is adjusted during repeated sprints in order not to surpass a critical threshold of peripheral fatigue. Twelve men randomly performed three experimental sessions on different days, i.e. one single 10 s all-out sprint and two trials of 10 × 10 s all-out sprints with 30 s of pas...

journal_title：Experimental physiology

authors： Hureau TJ,Olivier N,Millet GY,Meste O,Blain GM

更新日期：2014-07-01 00:00:00

abstract：:Lower body negative pressure (LBNP) reduces central venous pressure (CVP) and cardiac output. The elderly are reported to have a limited capacity to increase cardiac output by increasing heart rate (HR), are especially dependent on end diastolic volume to maintain stroke volume and therefore should be especially vulne...

journal_title：Experimental physiology

authors： van Hoeyweghen R,Hanson J,Stewart MJ,Dethune L,Davies I,Little RA,Horan MA,Kirkman E

更新日期：2001-05-01 00:00:00

abstract：:The vascular actions of insulin are complex, because it can stimulate both nitric oxide-mediated dilatation and endothelin (ET)-1-mediated constriction. We examined vasoreactivity to insulin in isolated feed arteries of the gastrocnemius (GFA) and soleus muscles (SFA) of 32-week-old Long-Evans Tokushima Otsuka (LETO) ...

journal_title：Experimental physiology

authors： Jenkins NT,Padilla J,Martin JS,Crissey JM,Thyfault JP,Rector RS,Laughlin MH

更新日期：2014-01-01 00:00:00

abstract：:Gastric motility was recorded from ferrets chronically prepared with an antral strain gauge. In fasted animals, antral motility showed cycles of activity and quiescence typical of the migrating motor complex (MMC) with a period of 44.7 +/- 6.1 min (n = 4). Anaesthesia with pentobarbitone sodium (50 mg/kg) disrupted th...

journal_title：Experimental physiology

authors： Grundy D

更新日期：1990-09-01 00:00:00

abstract：:Indirect evidence supporting a solute-coupled liquid absorption from the pleural space of rabbits has recently been provided; moreover, the beta 2-adrenoceptor agonist terbutaline has been found to increase this absorption. In this study the effect of adrenaline and alpha-adrenoceptor agonists on net rate of liquid ab...

journal_title：Experimental physiology

authors： Zocchi L,Raffaini A,Agostoni E

更新日期：1997-05-01 00:00:00

abstract：:The present investigation was designed to examine whether calmodulin is involved in the inhibition of the ATP-sensitive K+ (K(ATP)) channel by glucagon-like peptide 1(7-36) amide (GLP-1) in mouse pancreatic beta-cells. Membrane potential, single channel and whole-cell currents through the K(ATP) channels, and intracel...

journal_title：Experimental physiology

authors： Ding WG,Kitasato H,Matsuura H

更新日期：2001-05-01 00:00:00

abstract：:Haemorrhagic shock (HS) and fluid resuscitation can lead to increased reactive oxygen species (ROS), contributing to ischaemia-reperfusion injury and organ damage. Ubiquinol is a potent antioxidant that decreases ROS. This study examined the effects of ubiquinol administered with fluid resuscitation following controll...

journal_title：Experimental physiology

authors： Bennetts P,Shen Q,Thimmesch AR,Diaz FJ,Clancy RL,Pierce JD

更新日期：2014-07-01 00:00:00

abstract：UNLABELLED:The modulation of activity of the upper airway dilator and respiratory muscles plays a key role in the regulation of ventilation, but little is known about the link between their neuromuscular activation processes in vivo. This study investigated genioglossus and diaphragm responses to transcranial magnetic ...

journal_title：Experimental physiology

authors： Wang W,Similowski T,Sériès F

更新日期：2007-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does sex or neonatal stress affect the expression of pituitary adenylate cyclase-activating peptide or its receptors? What is the main finding and its importance? Neonatal-maternal separation stress has little long-lasting effect on the expression of pituitary ad...

journal_title：Experimental physiology

authors： Mosca EV,Rousseau JP,Gulemetova R,Kinkead R,Wilson RJ

更新日期：2015-02-01 00:00:00