Cloning of a major heparan sulfate proteoglycan from brain and identification as the rat form of glypican.

abstract：:The endothelin system consists of three ligands (ET-1, ET-2 and ET-3) and at least two receptors (ETA and ETB). In mice ET-2 counterpart is a peptide originally called "vasoactive intestinal contractor" (VIC) for this reason, this peptide is frequently named ET-2/VIC. In intestinal villi, fibroblasts-like cells expres...

journal_title：Biochemical and biophysical research communications

authors： Bianchi M,Adur J,Takizawa S,Saida K,Casco VH

更新日期：2012-01-27 00:00:00

abstract：:Cycloheximide (CYH) resistance in Candida maltosa is dependent on the induction of a ribosomal protein, Q-type L41, the 56th residue of which is glutamine, not proline as in ordinary P-type L41. We found that a 38-kDa protein in a wild-type C. maltosa ribosomal fraction became undetectable upon CYH treatment but detec...

journal_title：Biochemical and biophysical research communications

authors： Takaku H,Mutoh E,Horiuchi H,Ohta A,Takagi M

更新日期：2001-06-01 00:00:00

abstract：:Almost all bacteria require iron for growth and virulence expression. However, Listeria spp. do not produce any siderophore for iron acquisition. Representative strains of each of the six species of Listeria were examined for their ability to use various compounds as iron suppliers in iron-restricted medium. Here we s...

journal_title：Biochemical and biophysical research communications

authors： Coulanges V,Andre P,Vidon DJ

更新日期：1998-08-19 00:00:00

abstract：:Transforming growth factor beta (TGFbeta) is a critical immunosuppressive cytokine that inhibits the cell-mediated immune responses partly via inhibition of immunostimulatory cytokine production from T cells, NK cells, and macrophages. Here we investigated the effect of TGFbeta on NK cell activation induced by interle...

journal_title：Biochemical and biophysical research communications

authors： Hayashi H,Inoue Y,Tsutsui H,Okamura H,Nakanishi K,Onozaki K

更新日期：2003-01-24 00:00:00

abstract：:The association of endogenous synenkephalin and met-enkephalin containing peptides with the membrane of bovine chromaffin granules and physicochemical characteristics of this association were studied. The associated materials were only released at a non physiological pH range and this effect was enhanced with growing ...

journal_title：Biochemical and biophysical research communications

authors： Ase A,Vindrola O,Aloyz R,Inés M,Vida R,Finkielman S,Nahmod V

更新日期：1989-02-15 00:00:00

abstract：:5-Lipoxygenase (5LO) catalyzes two steps in the biosynthesis of leukotrienes (LTs), lipid mediators of inflammation derived from arachidonic acid. LTs function in normal host defense, and have pathophysiological roles in chronic inflammatory diseases as asthma and atherosclerosis. Also, possible effects of 5LO product...

journal_title：Biochemical and biophysical research communications

authors： Rådmark O,Samuelsson B

更新日期：2010-05-21 00:00:00

abstract：:Oxygen resistant N2-fixing Escherichia coli, which can grow at a high oxygen concentration in a nitrogen-free medium, were produced by several times of cultivation under a condition of 0.03% oxygen. Six isolated resistant strains could grow at an oxygen concentration ten times that of the parent strain. The nif-genes ...

journal_title：Biochemical and biophysical research communications

authors： Iwahashi H,Someya J

更新日期：1990-04-16 00:00:00

abstract：:This report describes the in vivo phosphorylation of isocitrate lyase and examines the possible consequences to the control of the Kreb's cycle and glyoxylate bypass. NADP-specific isocitrate dehydrogenase from E. coli was the first bacterial protein whose enzymic activity was shown to be modulated by reversible phosp...

journal_title：Biochemical and biophysical research communications

authors： Hoyt JC,Reeves HC

更新日期：1988-06-16 00:00:00

abstract：:The aim of this study was to illustrate the further process of 24p3 protein after association with epididymal spermatozoa. We have previously identified a caput-initiated 24p3 protein, which interacts with the spermatozoa surface in vitro. In the present study, we investigate another role of the 24p3 protein with sper...

journal_title：Biochemical and biophysical research communications

authors： Elangovan N,Lee YC,Tzeng WF,Chu ST

更新日期：2004-07-09 00:00:00

abstract：:The effect of sex steroids on the regulation of hepatocyte resting membrane potential (Em) was investigated. In adult rat liver snips, Em was significantly lower in males than females. In prepubertal animals no sex related difference was observed and the Em was comparable to that of adult females. Exposure of the huma...

journal_title：Biochemical and biophysical research communications

authors： Motzkin SM,Feinstein J,Tiribelli C

更新日期：1990-11-15 00:00:00

abstract：:The trophoblast-like choriocarcinoma cell line BeWo expresses a receptor for vascular endothelial growth factor (VEGF) and proliferates in response to VEGF. Nitric oxide (NO) seems to play a key role in the VEGF-induced proliferation of endothelial cells but the NO mechanistic regulation of VEGF-stimulated trophoblast...

journal_title：Biochemical and biophysical research communications

authors： Cha MS,Lee MJ,Je GH,Kwak JY

更新日期：2001-04-13 00:00:00

abstract：:The classified sediment with ethanol from sera of nude mice and humans showed a disturbing effect on L1210 cells in vitro and a lifesaving effect on L1210 cell-bearing mice in vivo. This factor was purified more than 2300-fold to a specific activity of approximately 1 X 10(5) U/mg by ethanol classified precipitation, ...

journal_title：Biochemical and biophysical research communications

authors： Sakagami Y,Manabe H

更新日期：1984-04-30 00:00:00

abstract：:RANTES is a cytokine produced by activated T-lymphocytes that has been shown to exert chemotactic activity for memory-type CD4 T-lymphocytes and eosinophils. In this study, RANTES caused directional migration of human mast cells. When compared to other potential chemoattractants of the same cells, RANTES was found to ...

journal_title：Biochemical and biophysical research communications

authors： Mattoli S,Ackerman V,Vittori E,Marini M

更新日期：1995-04-06 00:00:00

abstract：:Blot-hybridization of sea urchin (Tripneustes gratilla) genomic DNA with a cloned rDNA probe revealed individual variation in the length of the rDNA repeat unit and also in the non-transcribed spacer sequences. The number of distinct rDNA repeat subclasses distinguishable within any one sea urchin was limited and usua...

journal_title：Biochemical and biophysical research communications

authors： Simmen FA,Mandel M,Humphreys T

更新日期：1986-06-13 00:00:00

abstract：:Gonadotropin releasing hormone (GnRH), preincubated with cultured rat pituitary cells, induced down regulation of GnRH receptors in a time- and dose-dependent manner. The specific binding was inhibited by 50% after 30 min and maximal inhibition (70%) was obtained after 75 min preincubation with 1 microM GnRH. Preincub...

journal_title：Biochemical and biophysical research communications

authors： Hazum E,Schvartz I

更新日期：1984-12-14 00:00:00

abstract：:GOTO cells, a neuroblastoma cell line retaining the ability to differentiate into neuronal or Schwann cells, were found to be rich in membrane rafts containing ganglioside GM2 and hypersensitive to lipid raft-disrupting methyl-beta-cyclodextrin (MbetaCD); the GM2-rich rafts and sensitivity to MbetaCD were markedly dim...

journal_title：Biochemical and biophysical research communications

authors： Tomioka R,Minami N,Kushida A,Horibe S,Izumi I,Kato A,Fukushima K,Ideo H,Yamashita K,Hirose S,Saito Y

更新日期：2009-11-06 00:00:00

abstract：:The cell surface of Candida albicans is enriched with highly glycosylated mannoproteins that are involved in the interaction with host tissues. N- and O-glycosylation are post-translational modifications that initiate in the endoplasmic reticulum, and finalize in the Golgi. The KRE2/MNT1 family encode a set of multifu...

journal_title：Biochemical and biophysical research communications

authors： Díaz-Jiménez DF,Mora-Montes HM,Hernández-Cervantes A,Luna-Arias JP,Gow NA,Flores-Carreón A

更新日期：2012-03-02 00:00:00

abstract：:The extracellular matrix regulates many fundamental cellular processes such as proliferation, migration, and differentiation. Among the ECM components, type I collagen induces endothelial tube formation in vitro. By analysing genes participating in this event, the bone morphogenetic protein receptor-II (BMPR-II) was d...

journal_title：Biochemical and biophysical research communications

authors： Regazzoni C,Winterhalter KH,Rohrer L

更新日期：2001-05-04 00:00:00

abstract：:Liver regeneration is regulated by several factors. Among these extracellular matrix plays a crucial role in the restoration of normal structure. Proteoglycans are major components of extracellular matrix and they are able to bind growth factors implicated in liver growth. We studied syndecan, perlecan, fibroglycan, a...

journal_title：Biochemical and biophysical research communications

authors： Gallai M,Sebestyén A,Nagy P,Kovalszky I,Onody T,Thorgeirsson SS

更新日期：1996-11-21 00:00:00

abstract：:Several studies have demonstrated that connexin 43 (Cx43) mediates signals important for osteoblast function and osteogenesis. The role of gap junctional communication in bone resorption is less clear. We have investigated the expression of Cx43 mRNA in osteoclasts and bone resorption cultures and furthermore, the fun...

journal_title：Biochemical and biophysical research communications

authors： Ransjö M,Sahli J,Lie A

更新日期：2003-04-18 00:00:00

abstract：:Atherosclerosis and cancer are the leading causes of mortality around the world that share common pathogenic pathways. The aim of this study is the investigation of the protein profile of atherosclerotic plaque in order to find similar biomarker between cancer and atherosclerosis. The small pieces of human coronary ar...

journal_title：Biochemical and biophysical research communications

authors： Fasehee H,Fakhraee M,Davoudi S,Vali H,Faghihi S

更新日期：2019-02-12 00:00:00

abstract：:Two cDNA clones for the transacylase protein of the branched chain ketoacid dehydrogenase complex [E.C. 1.2.4.4] have been isolated from a human fetal liver cDNA expression library in lambda gt11 using antibody selection. By selective antibody elution from nitrocellulose filters containing the fusion proteins, it was ...

journal_title：Biochemical and biophysical research communications

authors： Litwer S,Danner DJ

更新日期：1985-09-16 00:00:00

abstract：:In cranial skeletal development, the establishment of the ectomesenchymal lineage within the cranial neural crest is of great significance. Fgfs are polypeptide growth factors with diverse functions in development and metabolism. Fgf20b knockdown zebrafish embryos showed dysplastic neurocranial and pharyngeal cartilag...

journal_title：Biochemical and biophysical research communications

authors： Yamauchi H,Goto M,Katayama M,Miyake A,Itoh N

更新日期：2011-06-17 00:00:00

abstract：:The age-related reduction in the function of osteoblasts plays a central role in the pathogenesis of bone loss and osteoporosis. Collagen synthesis is a primary function of differentiated osteoblasts, however, the mechanisms for age-related changes in collagen synthesis in human osteoblasts remain elusive. We use Gene...

journal_title：Biochemical and biophysical research communications

authors： Zhang X,Zhao G,Zhang Y,Wang J,Wang Y,Cheng L,Sun M,Rui Y

更新日期：2018-10-12 00:00:00

abstract：:Cilia are microtubule-based organelles that are present on the surfaces of almost all vertebrate cells. Most cilia function as sensory or molecular transport structures. Malfunctions of cilia have been implicated in several diseases of human development. The assembly of cilia is initiated by the centriole (or basal bo...

journal_title：Biochemical and biophysical research communications

authors： Nagai Y,Asaoka Y,Namae M,Saito K,Momose H,Mitani H,Furutani-Seiki M,Katada T,Nishina H

更新日期：2010-06-11 00:00:00

abstract：:p120-Catenin is known to play important roles in cell-cell adhesion stability by binding to cadherin and morphological changes of cells by regulating small RhoGTPase activities. Although the expression and binding states of p120-catenin are thought to dynamically change due to morphological adaptation of endothelial c...

journal_title：Biochemical and biophysical research communications

authors： Sakamoto N,Segawa K,Kanzaki M,Ohashi T,Sato M

更新日期：2010-07-30 00:00:00

abstract：:Lipopolysaccharide (LPS)-induced multiple organ injury was mediated in part by a transcription factor, nuclear factor-kappaB (NF-kappaB). Mice were pretreated with dexamethasone (DEX), an inhibitor of NF-kappaB activation, to elucidate its effects on LPS-induced early responses in vivo. Early responses measured 1 h af...

journal_title：Biochemical and biophysical research communications

authors： Aoki K,Ishida Y,Kikuta N,Kawai H,Kuroiwa M,Sato H

更新日期：2002-06-28 00:00:00

abstract：:Three immunoreactive prolactin proteins (24 Kd, 16 Kd, and 12 Kd) were identified in the rat brain using sodium dodecyl sulphate polyacrylamide gel electrophoresis, and western blot analyses. In male and female brains, the primary prolactin protein has a molecular weight of 24 Kd which is similar to that of pituitary ...

journal_title：Biochemical and biophysical research communications

authors： DeVito WJ

更新日期：1988-01-29 00:00:00

abstract：:In rat basophilic leukemia cells (RBL-2H3) activation of the high affinity receptor for IgE induces tyrosine phosphorylation of PKC delta. We carried out solid phase synthesis of 15 amino acid long oligopeptides corresponding to the sequences around each of the 19 tyrosine residues in PKC delta. Only three oligopeptid...

journal_title：Biochemical and biophysical research communications

authors： Szallasi Z,Denning MF,Chang EY,Rivera J,Yuspa SH,Lehel C,Olah Z,Anderson WB,Blumberg PM

更新日期：1995-09-25 00:00:00

abstract：:Serine palmitoyltransferase long chain-1 (SPTLC1), which is the rate-limiting enzyme for sphingolipid biosynthesis, has been indicated to be essential for carcinoma cell survival and proliferation in recent, but its role in the regulation of renal cell carcinoma (RCC) remains unknown. In the present study, we found th...

journal_title：Biochemical and biophysical research communications

authors： Kong Z,Guo X,Zhao Z,Wu W,Luo L,Zhu Z,Yin S,Cai C,Wu W,Wang D,Liu Y,Duan X

更新日期：2019-11-26 00:00:00