Indomethacin and protein binding of methotrexate.

abstract：:Diazinon is one of the most widely used organophosphate insecticides (OPI) in agriculture and public health programs. The aim of this study was to investigate how an OPI, diazinon, affects lipid peroxidation (LPO) and the antioxidant defense system in vitro. For this purpose, two experiments were carried out. In exper...

journal_title：Human & experimental toxicology

authors： Altuntas I,Kilinc I,Orhan H,Demirel R,Koylu H,Delibas N

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Mushroom poisoning is still a significant health-care problem, with the potential to affect blood parameters. The present study analyses the effect of mushroom poisoning on complete blood cell parameters, cell ratios, and cell volume indices and the effect of the mentioned parameters on prognosis/hospital len...

journal_title：Human & experimental toxicology

authors： Doğan M,Karahan I

更新日期：2019-10-01 00:00:00

abstract：:Puerarin, a potent free radicals scavenger, has been demonstrated to have protective efficacy in oxidative damage induced by nephrotoxins. In the present study, the attenuating effect of puerarin (PU) on lead (Pb)-induced apoptosis and oxidative stress was investigated in cultured primary rat proximal tubular (rPT) ce...

journal_title：Human & experimental toxicology

authors： Liu G,Li Z,Wang J,Wang H,Wang Z,Wang L

更新日期：2014-10-01 00:00:00

abstract：:Diallyl sulfide, a sulfur-containing volatile compound present in garlic (Allium sativum), exerts anticarcinogenic activity in various rodent tumor models. In the present study, apoptosis-inhibiting effects of diallyl sulfide against a carcinogenic polycyclic aromatic hydrocarbon, 7,12-dimethyl benz(a)anthracene (DMBA...

journal_title：Human & experimental toxicology

authors： Prasad S,Kalra N,Srivastava S,Shukla Y

更新日期：2008-01-01 00:00:00

abstract：:This paper presents the findings of a study of serum pseudocholinesterase activity in a group of 36 industrial workers chronically exposed to organophosphorus (OP) compounds. The mean pseudocholinesterase level of the workers was significantly lower than that of 36 other workers without a history of similar exposure. ...

journal_title：Human & experimental toxicology

authors： Peedicayil J,Ernest K,Thomas M,Kanagasabapathy AS,Stephen PM

更新日期：1991-07-01 00:00:00

abstract：:This study was designed to determine the levels of prolactin, leptin, osteopontin, and follistatin in workers chronically and subacutely exposed to lead compounds. The examined population consisted of three groups. The first group was composed of 56 male workers who were chronically exposed to lead for 13.38 ± 10.38 y...

journal_title：Human & experimental toxicology

authors： Dobrakowski M,Kasperczyk A,Czuba ZP,Machoń-Grecka A,Szlacheta Z,Kasperczyk S

更新日期：2017-06-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic condition of the intestine with unknown etiology involving multiple immune, genetic and environmental factors. We were interested in examining the effect of a total extract from Ziziphora clinopoides, an Iranian folk herbal medicine, in the prevention and control of experi...

journal_title：Human & experimental toxicology

authors： Ghafari H,Yasa N,Mohammadirad A,Dehghan G,Zamani MJ,Nikfar S,Khorasani R,Minaie B,Abdollahi M

更新日期：2006-06-01 00:00:00

abstract：:The modulating effect of peroxisome proliferator-activated receptor α ligand on haemodynamic effects of phenylepherine (PE), angiotensin II (AII), endothelin 1 (ET1), acetylcholine (Ach), sodium nitroprusside (SNP) and isoproterenol (ISO) were evaluated in glycerol-induced acute kidney injury in rats. The effect of PE...

journal_title：Human & experimental toxicology

authors： Adedapo AA,Oyekan AO

更新日期：2013-03-01 00:00:00

abstract：:HCH isomers, endosulfan, malathion, chlorpyrifos, and methyl-parathion were monitored in human milk samples from Bhopal, Madhya Pradesh. The endosulfan concentrations were highest and exceeded the sigma-HCH, chlorpyrifos, and malathion concentrations by 3.5-, 1.5-, and 8.4-fold, respectively. Through breast milk, infa...

journal_title：Human & experimental toxicology

authors： Sanghi R,Pillai MK,Jayalekshmi TR,Nair A

更新日期：2003-02-01 00:00:00

abstract：:Manganese (Mn) is an essential nutrient required for proper growth and maintenance of numerous biological systems. At high levels it is known to be neurotoxic. While focused research concerning the transport of Mn across the blood-brain barrier (BBB) is on-going, the exact identity of the transporter(s) responsible is...

journal_title：Human & experimental toxicology

authors： Fitsanakis VA,Piccola G,Marreilha dos Santos AP,Aschner JL,Aschner M

更新日期：2007-04-01 00:00:00

abstract：:The time-dependent changes in lead (Pb) concentrations in major tissues, serum and urine, and the Pb biomarker delta-aminolevulinic acid (ALA) concentration in urine were studied in rats after sub-chronic Pb exposure. Female Sprague-Dawley (SD) rats were exposed to Pb in drinking water at concentrations of 100 ppm and...

journal_title：Human & experimental toxicology

authors： Kang HG,Jeong SH,Cho MR,Cho JH,Bischoff K

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:Calcium channel blockers (CCBs) were the most common agents associated with a significant morbidity and mortality rate. The main objective of this study was to examine the publication pattern related to CCBs poisoning at the global level using bibliometric analysis of articles published in SciVerse Scopus onlin...

journal_title：Human & experimental toxicology

authors： Zyoud SH,Al-Jabi SW,Sweileh WM,Waring WS

更新日期：2015-11-01 00:00:00

abstract：:The aim of this study was to evaluate the scores of the Acute Physiology and Chronic Health Evaluation (APACHE) II and a modified APACHE II system (MAS), without parameters of biochemical tests; and to find prognostic value of individual elements of the APACHE II and MAS in predicting outcomes in organophosphate (OP) ...

journal_title：Human & experimental toxicology

authors： Eizadi-Mood N,Saghaei M,Jabalameli M

更新日期：2007-07-01 00:00:00

abstract：AIM:To assess the systemic inflammatory response (SIR) and the multi-organ damage after large-volume liver radiofrequency ablation (RFA) with or without concurrent Pringle maneuver. METHODS:Wistar rats were subjected to 30% liver RFA (group RFA), liver RFA under 30-min Pringle maneuver (group RFA + P), Pringle only (g...

journal_title：Human & experimental toxicology

authors： Ypsilantis P,Lambropoulou M,Anagnostopoulos C,Tsigalou C,Vasiliadis C,Kortsaris A,Papadopoulos N,Simopoulos C

更新日期：2011-11-01 00:00:00

abstract：:The regulation of osteoblast proliferation is a key factor in maintaining bone mass. The enhancement of this process can be achieved by stimulating the proliferation of these cells. Mechanical stimulation is one of the important enhancing factors, but the exact cellular mechanisms of mechanical stimulation, i.e., mech...

journal_title：Human & experimental toxicology

authors： Rosenberg N

更新日期：2003-05-01 00:00:00

abstract：:Teucrium polium L. (Lamiaceae) is a commonly used medicinal plant in folk medicine. Among several uses, T. polium is used to treat male fertility problems. This research was conducted to study the effect of T. polium on spermatogenesis, testosterone level, androgen receptor expression, and fertility in male rats. Admi...

journal_title：Human & experimental toxicology

authors： Al-Tikriti A,Al-Khateeb E,Abbas MA

更新日期：2017-12-01 00:00:00

abstract：:Trichothecenes are mycotoxins produced by various species of fungi which can occur on various agricultural products. Among these compounds, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS) and deoxynivalenol (DON) are the most naturally encountered and potent trichothecenes. Consumption of trichothecene contaminated fo...

journal_title：Human & experimental toxicology

authors： Rio B,Lautraite S,Parent-Massin D

更新日期：1997-11-01 00:00:00

abstract：:Diepoxybutane (DEB)- and mitomycin C (MMC)-associated toxicity was investigated in embryos from the sea urchin (SU) species Sphaerechinus granularis. DEB- and MMC-induced toxicity resulted in S. granularis embryos and larvae at concentrations ranging 10(-5) to 10(-4) M DEB, and 3 x 10(-6) to 3 x 10(-5) M MMC, in terms...

journal_title：Human & experimental toxicology

authors： Pagano G,Degan P,De Biase A,Iaccarino M,Warnau M

更新日期：2001-12-01 00:00:00

abstract：:The number of definite and probable human chemical carcinogens identified by IARC approaches between 1987 and June 2004 is reported to be 50 agents. However, overall, given the rapid expansion in the number of chemicals in use, the throughput of the current approach to identifying potential environmental carcinogens i...

journal_title：Human & experimental toxicology

authors： Battershill JM

更新日期：2005-11-01 00:00:00

abstract：:The current study was undertaken to evaluate the effect of combined therapy of gabapentin and pantoprazole against forestomach and pylorus ligation-induced gastric esophageal reflux disease (GERD) in albino Wistar rats. Rats were randomly divided into five groups, each group consisting of six rats, fasted for 24 h, un...

journal_title：Human & experimental toxicology

authors： Arya P,Kaithwas G

更新日期：2020-04-01 00:00:00

abstract：:Formaldehyde is a physiological intermediary metabolite taking part in many biological process in the body. It is a constituent of many items of daily use, including foods. It is also used in medicine for treatment of some conditions. A 40% solution of formaldehyde in water is known as formalin. Formalin is irritating...

journal_title：Human & experimental toxicology

authors： Pandey CK,Agarwal A,Baronia A,Singh N

更新日期：2000-06-01 00:00:00

abstract：:Cyanate and its active form isocyanate are formed mainly in the process of nonenzymatic urea biodegradation. Cyanate is capable of protein S- and N-carbamoylation, which can affect their activity. The present studies aimed to demonstrate the effect of cyanate on activity of the enzymes implicated in anaerobic cysteine...

journal_title：Human & experimental toxicology

authors： Iciek M,Bilska A,Lorenc-Koci E,Wlodek LB,Sokołowska MM

更新日期：2011-10-01 00:00:00

abstract：:The National Toxicology Program (NTP) Technical Reports online database was reviewed to find chemicals that were reported to show clear evidence of carcinogenicity in the NTP rodent studies and for which data on human exposure could be found. Six representative compounds were selected. Three volatile compounds: ethyl ...

journal_title：Human & experimental toxicology

authors： Waddell WJ

更新日期：2003-09-01 00:00:00

abstract：:Members of the transforming growth factor (TGF) family have emerged as critical contributors to the choreography of cellular and tissue interactions underlying morphogenesis of the orofacial region. The TGFs beta, and their downstream effector molecules, the Smads, play a pivotal role in normal as well as abnormal dev...

journal_title：Human & experimental toxicology

authors： Greene RM,Pisano MM

更新日期：2005-01-01 00:00:00

abstract：:Phosphorus flame retardants are a group of chemicals that are used to slow or prevent the spread of fire. These compounds have been detected in different environments including human organism. In the present study, we have investigated DNA-damaging potential and effect on DNA methylation of tris(2-chloroethyl) phospha...

journal_title：Human & experimental toxicology

authors： Bukowski K,Wysokinski D,Mokra K,Wozniak K

更新日期：2019-06-01 00:00:00

abstract：:This study deals with pesticide exposure profile in some European countries with a specific focus on ethylenebisdithiocarbamates (EBDC). In all, 55 Bulgarian greenhouse workers, 51 Finnish potato farmers, 48 Italian vineyard workers, 42 Dutch floriculture farmers, and 52 Bulgarian zineb producers entered the study. Ea...

journal_title：Human & experimental toxicology

authors： Fustinoni S,Campo L,Liesivuori J,Pennanen S,Vergieva T,van Amelsvoort L,Bosetti C,Van Loveren H,Colosio C

更新日期：2008-09-01 00:00:00

abstract：:This study was designed to investigate the effect of agmatine sulfate (AG, CAS2482-00-0) in nicotine (NIC)-induced vascular endothelial dysfunction (VED) in rabbits. NIC was administered to produce VED in rabbits with or without AG for 6 weeks. Serum lipid profile, serum thiobarbituric acid reactive substances, reduce...

journal_title：Human & experimental toxicology

authors： Nader MA,Gamiel NM,El-Kashef H,Zaghloul MS

更新日期：2016-05-01 00:00:00

abstract：:Progesterone (a neurosteroid) is an important modulator of the nervous system functioning. Organophosphorus pesticides like phosphamidon have been shown to adversely affect memory and induce oxidative stress on both acute and chronic exposure. The present study was therefore designed to investigate the effects of prog...

journal_title：Human & experimental toxicology

authors： Sharma AK,Bhattacharya SK,Khanna N,Tripathi AK,Arora T,Mehta AK,Mehta KD,Joshi V

更新日期：2011-10-01 00:00:00

abstract：:Lipid peroxidation is one of the main manifestations of oxidative damage and has been found to play an important role in the toxicity and carcinogenicity of many xenobiotics. In the present study, we investigated the possible induction of lipid peroxidation by aluminium in human foreskin fibroblast cultures by assayin...

journal_title：Human & experimental toxicology

authors： Anane R,Creppy EE

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to determine oxidant and antioxidant status in infants with hyperbilirubinemia and/or kernicterus and to find whether there is a relationship between bilirubin level and oxidant/antioxidant status. PATIENTS:The study includes 69 full-term newborns (neonates with hyperbi...

journal_title：Human & experimental toxicology

authors： Doğan M,Peker E,Kirimi E,Sal E,Akbayram S,Erel O,Ocak AR,Tuncer O

更新日期：2011-11-01 00:00:00