Differential effects of butylated hydroxytoluene analogs on bull sperm subjected to cold-induced membrane stress.

Abstract:

:Previous reports established that butylated hydroxy toluene (BHT) minimized cold-induced membrane rupture in sperm from several species. No data regarding the specificity of its effect is available. In this study 25 BHT analogs were tested for their effect on bovine sperm membrane stability. Fourteen were membrane lytic at 25 degrees C and 6 were neither membrane lytic nor membrane stabilizing. The remaining 5 compounds, a family of 2,6-tert-butyl phenols with substitutions at position 4 of hydrogen, methyl (BHT), ethyl, butyl, hexyl, or octyl, afforded effective membrane protection to cold shock. Since membrane protection is a function of both the ability of a compound to partition into the membrane and a molecule's effectiveness once there, an analysis of each analog's membrane partitioning, assessed by measuring the cellular analog/cholesterol ratio, showed the following extents of transfer for the analogs: ethyl = butyl greater than methyl = hydrogen greater than hexyl greater than octyl. Thus, an optimum chain length exists for partitioning from micellar donors into cells. A separate experiment established that all analogs, when incorporated in equivalent amounts, protect equally plasma and mitochondrial membranes from cold shock. No effect on acrosomal membrane stability was noted. BHT, but not the other analogs, reduced sperm motility. Addition of egg yolk to extender containing BHT analog protected sperm motility from cold shock but had little effect on membrane stabilization. Analysis of sperm membrane compartments revealed that little to no analog was partitioned into the outer acrosomal membrane or the plasma membrane overlying the acrosome, but rather was localized in other portions of the sperm. We conclude that (a) the effective BHT analogs, if partitioned into the membrane, are indistinguishable with regard to their capacity to eliminate cold-induced membrane lysis; (b) membrane-linked events (e.g., motility) are uniquely disrupted by a subset of this analog family; and (c) when concentrations of egg yolk and BHT analogs are carefully controlled, unique synergistic effects are noted.

journal_name

Cryobiology

journal_title

Cryobiology

authors

Graham JK,Hammerstedt RH

doi

10.1016/0011-2240(92)90010-y

subject

Has Abstract

pub_date

1992-02-01 00:00:00

pages

106-17

issue

1

eissn

0011-2240

issn

1090-2392

pii

0011-2240(92)90010-Y

journal_volume

29

pub_type

杂志文章
  • 0 °C is better?- Thawing temperature optimization study for cancer cryoablation in a mouse model with green fluorescent protein-labeled Lewis lung cancer.

    abstract:PURPOSE:There are two kinds of thawing temperatures commonly adopted in cancer cryosurgery. We attempted to compare their efficacy differences in this study to optimize the surgical method. METHOD:Forty-five C57BL/6 J mice with GFP-labeled Lewis lung cancer were randomized into three groups (n = 15 for each): control ...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2017.01.008

    authors: Zhou T,Li Q,Chi X,Li L,Rao J,Hu K

    更新日期:2017-04-01 00:00:00

  • Direct ethanol fermentation from lignocellulosic biomass by Antarctic basidiomycetous yeast Mrakia blollopis under a low temperature condition.

    abstract::Antarctic basidiomycetous yeast Mrakia blollopis SK-4 has unique fermentability for various sugars under a low temperature condition. Hence, this yeast was used for ethanol fermentation from glucose and also for direct ethanol fermentation (DEF) from cellulosic biomass without/with Tween 80 at 10°C. Maximally, 48.2 g/...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2013.06.003

    authors: Tsuji M,Goshima T,Matsushika A,Kudoh S,Hoshino T

    更新日期:2013-10-01 00:00:00

  • Metabolic differences between cold stored and machine perfused porcine kidneys: A 1H NMR based study.

    abstract::Hypothermic machine perfusion (HMP) and static cold storage (SCS) are the two methods used to preserve deceased donor kidneys prior to transplant. This study seeks to characterise the metabolic profile of HMP and SCS porcine kidneys in a cardiac death donor model. Twenty kidneys were cold flushed and stored for two ho...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2016.11.006

    authors: Nath J,Smith TB,Patel K,Ebbs SR,Hollis A,Tennant DA,Ludwig C,Ready AR

    更新日期:2017-02-01 00:00:00

  • Osteogenic differentiation of GFP-labeled human umbilical cord blood derived mesenchymal stem cells after cryopreservation.

    abstract::The osteogenic capacity of human umbilical cord blood derived mesenchymal stem cells (UCB-MSCs) has been demonstrated both in vitro and in vivo. Therefore, cell labeling and storage are becoming necessary for researching the potential therapeutic use of UCB-MSCs for bone tissue engineering. The aim of this study was t...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2011.05.005

    authors: Liu G,Ye X,Zhu Y,Li Y,Sun J,Cui L,Cao Y

    更新日期:2011-10-01 00:00:00

  • Magnetic resonance imaging-estimated three-dimensional temperature distribution in liver cryolesions: a study of cryolesion characteristics assumed necessary for tumor ablation.

    abstract::The goal of this study was to estimate the three-dimensional (3D) temperature distribution in liver cryolesions and assess the margin of the transition zone between the tumoricidal core of the lesion and the surrounding unfrozen tissue, using criteria proposed in the literature. Local recurrences after liver tumor cry...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1006/cryo.2001.2351

    authors: Mala T,Samset E,Aurdal L,Gladhaug I,Edwin B,Søreide O

    更新日期:2001-11-01 00:00:00

  • Effect of sulforaphane on apoptosis, reactive oxygen species and lipids peroxidation of human sperm during cryopreservation.

    abstract::Sperm cryopreservation is a common procedure to preserve viable sperm for an indefinite period. This procedure has numerous detrimental effects on sperm function due to increased generation of reactive oxygen species (ROS). During cryopreservation, while ROS increases, antioxidant enzymes level decreases. It has been ...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2020.11.012

    authors: Valipour J,Nashtaei MS,Khosravizadeh Z,Mahdavinezhad F,Nekoonam S,Esfandyari S,Amidi F

    更新日期:2020-11-26 00:00:00

  • Strategies for exploration of freeze responsive gene expression: advances in vertebrate freeze tolerance.

    abstract::Winter survival for many cold-blooded species involves freeze tolerance, the capacity to endure the freezing of a high percentage of total body water as extracellular ice. The wood frog (Rana sylvatica) is the primary model animal used for studies of vertebrate freeze tolerance and current studies in my lab are focuse...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2003.10.008

    authors: Storey KB

    更新日期:2004-04-01 00:00:00

  • Problems of cryohemorrhoidectomy.

    abstract::One thousand cryohemorrhoidectomies were performed in the past 7 years (1973-1979). Ninety percent of the patients were satisfied with the technique; approximately one-third of the patients experienced severe to moderate pain and 11% had recurrences or related problems. The majority of patients with postoperative pain...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(82)90154-7

    authors: Oh C

    更新日期:1982-06-01 00:00:00

  • Environmental stress responsive expression of the gene li16 in Rana sylvatica, the freeze tolerant wood frog.

    abstract::Wood frogs (Rana sylvatica) can endure weeks of subzero temperature exposure during the winter with up to 65% of their body water frozen as extracellular ice. Associated with freezing survival is elevated expression of a number of genes/proteins including the unidentified gene, li16, first described in liver. The curr...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2012.01.008

    authors: Sullivan KJ,Storey KB

    更新日期:2012-06-01 00:00:00

  • Cryopreservation of turkey semen: effect of breeding line and freezing method on post-thaw sperm quality, fertilization, and hatching.

    abstract::Cryopreservation methods for poultry semen are not reliable for germplasm preservation, especially for turkeys, where fertility rates from frozen/thawed semen are particularly low. The objective was to evaluate cryopreservation methods for effectiveness in promoting cryosurvival and post-thaw function of sperm from fi...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2014.04.003

    authors: Long JA,Purdy PH,Zuidberg K,Hiemstra SJ,Velleman SG,Woelders H

    更新日期:2014-06-01 00:00:00

  • A fundamental study of cryoablation on normal bone: diagnostic imaging and histopathology.

    abstract::Cryoablation is a minimally invasive cancer treatment. In this study, the effects of cryoablation on normal rabbit bone were evaluated using imaging and histopathological examinations. Cryoablation was performed using a Cryo-Hit (Galil Medical, Yokneam, Israel). Under anesthesia, one cryoablation needle was inserted a...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2014.07.010

    authors: Yoshimoto Y,Azuma K,Miya A,Makino E,Nakamoto H,Abe N,Kaburagi M,Ueda H,Kuroda K,Tsuka T,Sugiyama A,Imagawa T,Murahata Y,Itoh N,Osaki T,Shimizu T,Okamoto Y

    更新日期:2014-10-01 00:00:00

  • Cryohemostasis of uncontrolled hemorrhage from liver injury.

    abstract::Uncontrolled hemorrhage is the primary cause of death in both blunt and penetrating liver trauma. Cryohemostasis was attempted in the past for elective liver surgery but did not gain popularity. During past decades, cryoequipment was refined and successfully used for tumor ablation. The purpose of the present study wa...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1006/cryo.2000.2239

    authors: Kopelman D,Klein Y,Zaretsky A,Ben-Izhak O,Michaelson M,Hashmonai M

    更新日期:2000-05-01 00:00:00

  • Non-disaccharide-based mechanisms of protection during drying.

    abstract::Few tissues or organisms can survive the removal of nearly all their intra and extracellular water. These few have developed specialized adaptations to protect their cellular components from the damage caused by desiccation and rehydration. One mechanism, common to almost all such organisms, is the accumulation of dis...

    journal_title:Cryobiology

    pub_type: 杂志文章,评审

    doi:10.1006/cryo.2001.2359

    authors: Oliver AE,Leprince O,Wolkers WF,Hincha DK,Heyer AG,Crowe JH

    更新日期:2001-09-01 00:00:00

  • Systematic factor optimization for cryopreservation of shipped sperm samples of diploid Pacific Oysters, Crassostrea gigas.

    abstract::Despite some 26 published reports addressing oyster sperm cryopreservation, systematic factor optimization is lacking, and sperm cryopreservation has not yet found application in aquaculture on a commercial scale. In this study, the effects of cooling rate, single or combined cryoprotectants at various concentrations,...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2005.06.007

    authors: Dong Q,Huang C,Eudeline B,Tiersch TR

    更新日期:2005-10-01 00:00:00

  • Pre-grafting histological studies of skin grafts cryopreserved in α helix antarctic yeast oriented antifreeze peptide (Afp1m).

    abstract::A number of living creatures in the Antarctic region have developed characteristic adaptation of cold weather by producing antifreeze proteins (AFP). Antifreeze peptide (Afp1m) fragment have been designed in the sequence of strings from native proteins. The objectives of this study were to assess the properties of Afp...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2019.09.012

    authors: Khan MS,Ibrahim SM,Adamu AA,Rahman MBA,Bakar MZA,Noordin MM,Loqman MY

    更新日期:2020-02-01 00:00:00

  • Effect of cooling rate on the survival of larvae, pupariation, and adult emergence of the gallfly Eurosta solidaginis.

    abstract::Freeze-tolerant third instar larvae of the gallfly Eurosta solidaginis were cooled at 10, 5, 1, and 0.1 degrees C min-1 to -40 degrees C and then warmed to +5 degrees C at 1 degree C min-1. After cooling and warming the larvae were transferred to 21 degrees C and the survival of larvae, success of pupariation, and adu...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(89)90024-2

    authors: Bale JS,Hansen TN,Nishino M,Baust JG

    更新日期:1989-06-01 00:00:00

  • Comparison of four different permitting and combination of two best cryoprotectants on freezing Nguni sperm evaluated with the aid of computer aided sperm analysis.

    abstract::Cryopreservation has been reported to damage approximately 40-50% of viable sperm in bull semen. The present study was undertaken to assess the cryo-effectiveness of glycerol (GLY), ethylene glycol (EG), dimethyl sulfoxide (DMSO) and propylene glycol (PND) as cryoprotectant during the cryopreservation of Nguni bull se...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2016.04.001

    authors: Seshoka MM,Mphaphathi ML,Nedambale TL

    更新日期:2016-06-01 00:00:00

  • Effects of centrifugation and lipid removal on the cryopreservation of in vitro produced bovine embryos at the eight-cell stage.

    abstract::The effects of intracellular lipid polarization and lipid removal treatments on the postthawed in vitro development of frozen bovine embryos at the 8-cell stage were studied. As the first step, bovine presumptive zygotes were centrifuged at 16,000 g for 20 min for the cytoplasmic lipid polarization and their lipid lay...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1006/cryo.1998.2077

    authors: Murakami M,Otoi T,Sumantri C,Suzuki T

    更新日期:1998-05-01 00:00:00

  • Vitrification of turbot embryos: preliminary assays.

    abstract::Successful fish embryo cryopreservation is still far from being achieved. Vitrification is considered the most promising option. Many factors are involved in the success of the process. The choice of a proper vitrification solution, the enzymatic permeabilization of embryos to increase cryoprotectant permeability, the...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/s0011-2240(03)00066-x

    authors: Robles V,Cabrita E,Real M,Alvarez R,Herráez MP

    更新日期:2003-08-01 00:00:00

  • Trehalose loading into red blood cells is accompanied with hemoglobin oxidation and membrane lipid peroxidation.

    abstract::One of the recent approaches to enhance desiccation tolerance in red blood cells (RBCs) is by loading trehalose. This process has been shown to increase the recovery of lyophilized RBCs; conversely, it results in cellular damage including hemoglobin oxidation and loss of membrane integrity. The purpose of this study w...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2008.12.003

    authors: Kanias T,Acker JP

    更新日期:2009-04-01 00:00:00

  • The role of freezing in trypsin activity oscillations.

    abstract::The importance of the frozen phase in the formation of cryooscillations of trypsin activity has been shown in experiments conducted at -10 degrees C under frozen and supercooled conditions, respectively. A solution containing trypsin obtained by trypsinogen activation and 0.1 M MnCl2 was distributed in test tubes with...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(92)90055-7

    authors: Vajda T

    更新日期:1992-08-01 00:00:00

  • The future of cryoablation: An abscopal effect.

    abstract::Cryoablation has become a popular modality to treat a variety of malignant tumors in solid organs and soft tissues. In the future, the use of cryoablation should focus on its abscopal effect. The present review discusses the increased immune response triggered by cryoablation alone or by cryoablation combined with imm...

    journal_title:Cryobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.cryobiol.2020.02.010

    authors: Chen J,Qian W,Mu F,Niu L,Du D,Xu K

    更新日期:2020-12-01 00:00:00

  • Development of vitrified mouse oocytes after in vitro fertilization.

    abstract::Mouse oocytes were cryopreserved by the vitrification method using vitrification solution (VSI) and the effects of dilution methods were examined on the rate of in vitro and in vivo development. Eighty-three percent and 75% of vitrified oocytes exhibited normal morphology when diluted in glycerol + sucrose and sucrose...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(91)90007-b

    authors: Kono T,Kwon OY,Nakahara T

    更新日期:1991-02-01 00:00:00

  • Influence of cell concentration on the contribution of unfrozen fraction and salt concentration to the survival of slowly frozen human erythrocytes.

    abstract::We have shown previously that the survival of human red blood cells during slow freezing at 2% hematocrit is dependent more on the magnitude of the unfrozen fraction than on the salt concentration in that unfrozen fraction. In parallel, first Nei and more recently Pegg and colleagues have shown that survival is affect...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(85)90029-x

    authors: Mazur P,Cole KW

    更新日期:1985-12-01 00:00:00

  • Collection, processing and freezing of equine bone marrow cells.

    abstract::There is no consensus on aspects of equine bone marrow collection and processing. The study aimed to describe the collection of large volumes of bone marrow from horses of advanced age, with emphasis on bone marrow mononuclear cells (BMMCs) recovery and viability after cryopreservation. Fourteen horses, aged 3-24 year...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2017.06.006

    authors: Bastos FZ,Barussi FCM,Santi TF,Vieira BP,Senegaglia AC,Cruz FF,Michelotto PV Jr

    更新日期:2017-10-01 00:00:00

  • Improved rat heart function after low Ca2+ perfused preservation at 5 degrees C for 18 hours.

    abstract::To evaluate the effect of Ca2+ on recovery of heart function after hypothermic preservation, isolated working rat hearts were perfused continuously in different [Ca2+] (0.35-2.0 mM) at 37 degrees C for 30 min, during cooling to 5 degrees C, and then at 5 degrees C for 1, 6 or 18 h. After rewarming to 37 degrees C, con...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1006/cryo.1994.1031

    authors: Liu B,Lopaschuk GD,Wang LC

    更新日期:1994-06-01 00:00:00

  • Altered tyrosine and tryptophan metabolism during hypothermic hibernation in the 13-lined ground squirrel (Spermophilus tridecemlineatus).

    abstract::(1) Tyrosine and tryptophan metabolism in brain and peripheral tissues were studied in hypothermic hibernating and normothermic nonhibernating 13-lined ground squirrels (Spermophilus tridecemlineatus). (2) In the hypothermic hibernating state, there were significant elevations of brain stem tyrosine, norepinephrine, a...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(87)90054-x

    authors: Weekley BL,Harlow HJ

    更新日期:1987-12-01 00:00:00

  • The effects of TETs on DNA methylation and hydroxymethylation of mouse oocytes after vitrification and warming.

    abstract::Oocyte vitrification has extensively been applied in the field of embryo engineering and in the preservation of genetic resources of fine livestock. Following our previous work in oocyte vitrification and the level change of DNA methylation, here we further explored the dynamic change of three active demethylation pro...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2019.09.001

    authors: Fu L,Chang H,Wang Z,Xie X,Chen H,Lei Z,Zhang Y,Quan F

    更新日期:2019-10-01 00:00:00

  • WITHDRAWN: Thermodynamic aspects of vitrification.

    abstract::The Publisher regrets that this article is an accidental duplication of an article that has already been published, doi:10.1016/j.cryobiol.2009.05.007. The duplicate article has therefore been withdrawn. ...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/j.cryobiol.2009.05.006

    authors: Wowk B

    更新日期:2009-06-06 00:00:00

  • The effects of different concentrations of glycerol and dimethylsulfoxide on the metabolic activities of kidney slices.

    abstract::Kidney slices either were exposed to the cryoprotectants for 1 hr at room temperature and subsequently washed and incubated in fresh KR buffer containing only the radioactive metabolic tracers, or were immediately incubated for 2 hr at 37 degrees C in KR buffer containing the cryoprotectant and the tracers. Exposure t...

    journal_title:Cryobiology

    pub_type: 杂志文章

    doi:10.1016/0011-2240(83)90059-7

    authors: Penninckx F,Cheng N,Kerremans R,Van Damme B,De Loecker W

    更新日期:1983-02-01 00:00:00