Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer.

abstract：:The aim of this study was to examine the effects of oral and transdermal oestrogen replacement therapy on the risk of colorectal cancer. Data from a nested case-control study, designed to investigate the effect of hormone replacement therapy (HRT) on colorectal cancer were analysed. New cases of colorectal cancer, dia...

journal_title：British journal of cancer

authors： Csizmadi I,Collet JP,Benedetti A,Boivin JF,Hanley JA

更新日期：2004-01-12 00:00:00

abstract：:In a phase I study of weekly administered cisplatin combined with oral etoposide, we observed a partial response in 4 out of 11 patients with metastatic colorectal cancer. Subsequently, we performed a phase II study to investigate the activity of this combination as first-line treatment in this disease. Fourteen patie...

journal_title：British journal of cancer

authors： Planting AS,van der Burg ME,van den Bent MJ,de Boer-Dennert M,Stoter G,Verweij J

更新日期：1996-05-01 00:00:00

abstract：:One hundred and seventy-eight patients with non metastatic inflammatory breast cancer (IBC) have been treated at the Centre H. Becquerel. Median follow up is 67 months (6-178). Every patient received neoadjuvant chemotherapy (mean number of cycles = 4; range: 2-8), followed by a loco regional treatment (radiotherapy =...

journal_title：British journal of cancer

authors： Chevallier B,Bastit P,Graic Y,Menard JF,Dauce JP,Julien JP,Clavier B,Kunlin A,D'Anjou J

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Tongue squamous cell carcinoma (TSCC) is increasing in incidence, especially among young patients and preferably females. Infection with human papilloma virus (HPV) has been suggested as a cause of SCC in the head and neck, and the proportion of oropharyngeal cancers caused by HPV has steadily increased. ME...

journal_title：British journal of cancer

authors： Sgaramella N,Coates PJ,Strindlund K,Loljung L,Colella G,Laurell G,Rossiello R,Muzio LL,Loizou C,Tartaro G,Olofsson K,Danielsson K,Fåhraeus R,Nylander K

更新日期：2015-07-14 00:00:00

abstract：:Secular, socioeconomic and urban-rural gradients and geographical differences in beef and fat consumption within the United States of America are compared with corresponding data on colorectal cancer incidence and mortality rates. These results, together with the results of most previous epidemiological studies, appea...

journal_title：British journal of cancer

authors： Enstrom JE

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Heterogeneity and low incidence comprise the biggest challenge in sarcoma diagnosis and treatment. Chemotherapy, although efficient for some sarcoma subtypes, generally results in poor clinical responses and is mostly recommended for advanced disease. Specific genomic aberrations have been identified in some...

journal_title：British journal of cancer

authors： Brodin BA,Wennerberg K,Lidbrink E,Brosjö O,Potdar S,Wilson JN,Ma L,Moens LN,Hesla A,Porovic E,Bernhardsson E,Papakonstantinou A,Bauer H,Tsagkozis P,von Sivers K,Wejde J,Östling P,Kallioniemi O,Stragliotto CL

更新日期：2019-02-01 00:00:00

abstract：:Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) and conventional malignant melanoma may demonstrate significant morphologic overlap at the light microscopic and ultrastructural level. Consequently, the clinically relevant distinction between primary clear cell sarcoma and metastatic me...

journal_title：British journal of cancer

authors： Langezaal SM,Graadt van Roggen JF,Cleton-Jansen AM,Baelde JJ,Hogendoorn PC

更新日期：2001-02-01 00:00:00

abstract：:Malignant melanoma (MM) is thought to arise by sequential accumulation of genetic alterations in normal melanocytes. Previous cytogenetic and molecular studies indicated the 9p21 as the chromosomal region involved in MM pathogenesis. In addition to the CDKN genes (p16/CDKN2A, p15/CDKN2B and p19(ARF), frequently inacti...

journal_title：British journal of cancer

authors： Palmieri G,Cossu A,Ascierto PA,Botti G,Strazzullo M,Lissia A,Colombino M,Casula M,Floris C,Tanda F,Pirastu M,Castello G,Melanoma Cooperative Group.

更新日期：2000-12-01 00:00:00

abstract：:Imatinib mesilate (Glivec), Novartis Pharmaceuticals) is a novel therapy for the treatment of chronic myeloid leukaemia (CML). We evaluated the cost-effectiveness of imatinib (600 mg daily) when used for the treatment of patients in advanced stages of CML (accelerated phase and blast crisis) against conventional thera...

journal_title：British journal of cancer

authors： Gordois A,Scuffham P,Warren E,Ward S

更新日期：2003-08-18 00:00:00

abstract：:The effect of 10(-6) M tamoxifen on MCF-7 cells adapted to growth in 0.5% foetal calf serum has been studied. The growth inhibitory effect of this tamoxifen concentration was abolished by simultaneous addition of 10(-8) M oestradiol, indicating that tamoxifen may exert its effect via binding to the oestrogen receptor....

journal_title：British journal of cancer

authors： Lykkesfeldt AE,Larsen JK,Christensen IJ,Briand P

更新日期：1984-06-01 00:00:00

abstract：:Helix pomatia agglutinin (HPA)- and Concanavalin A (Con A)-binding carbohydrate expression were studied on 32 tumour samples from primary adenocarcinoma of the breast and 12 samples from lymph node metastases. Live cells were spilled from each of the fresh samples and the extent of fluorescent-labelled HPA and Con A-b...

journal_title：British journal of cancer

authors： Alam SM,Whitford P,Cushley W,George WD,Campbell AM

更新日期：1990-08-01 00:00:00

abstract：:The serum CA125 level was determined by a one-step immunoradiometric assay method in patients with lung cancer. Increased serum CA125 levels were observed in 37.8% of patients with squamous cell cancer, in 30.0% of those with adenocarcinoma and in 60.0% of those with small call cancer. Most patients with increased ser...

journal_title：British journal of cancer

authors： Kimura Y,Fujii T,Hamamoto K,Miyagawa N,Kataoka M,Iio A

更新日期：1990-10-01 00:00:00

abstract：:Our recent genome-wide allelotyping analysis of gallbladder carcinoma identified 3p, 8p, 9q and 22q as chromosomal regions with frequent loss of heterozygosity. The present study was undertaken to more precisely identify the presence and location of regions of frequent allele loss involving those chromosomes in gallbl...

journal_title：British journal of cancer

authors： Wistuba II,Maitra A,Carrasco R,Tang M,Troncoso P,Minna JD,Gazdar AF

更新日期：2002-08-12 00:00:00

abstract：:The structural characteristics of mesoionic compounds, which contain distinct regions of positive and negative charges associated with a poly-heteroatomic system, enable them to cross cellular membranes and interact strongly with biomolecules. Potential biological applications have been described for mesoionic compoun...

journal_title：British journal of cancer

authors： Senff-Ribeiro A,Echevarria A,Silva EF,Franco CR,Veiga SS,Oliveira MB

更新日期：2004-07-19 00:00:00

abstract：:Two hundred and thirty five patients with osteosarcoma, aged less than 40 years, and treated by amputation or radiotherapy, were entered in a randomised trial of two forms of adjuvant chemotherapy. A two drug regimen, namely vincristine 2 mg m-2 (maximum 2mg) followed by methotrexate 200 mgm-2, given every three weeks...

journal_title：British journal of cancer

authors：

更新日期：1986-04-01 00:00:00

abstract：:The pathophysiology of Raynaud's phenomenon after Cisplatin-Bleomycin-Vinblastine combination chemotherapy, its relationship to polyneuropathy, and response to transcutaneous nerve stimulation (TNS), was studied in eight patients previously treated for testicular cancer. Peripheral circulation in the index finger was ...

journal_title：British journal of cancer

authors： Heier MS,Nilsen T,Graver V,Aass N,Fosså SD

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its frequency in breast cancer is not known. Assays to establish BRCAness would be extremely valuable for the clinical management of these tumours. We assessed BRCAness...

journal_title：British journal of cancer

authors： Lips EH,Mulder L,Oonk A,van der Kolk LE,Hogervorst FB,Imholz AL,Wesseling J,Rodenhuis S,Nederlof PM

更新日期：2013-05-28 00:00:00

abstract：:BNP7787 (disodium 2,2'-dithio-bis-ethane sulphonate; Tavocept) is a novel agent developed to protect against cisplatin (cis-diammine-dichloroplatinum(II))-associated chronic toxicities. In this study, we determined the recommended dose of BNP7787 when preceding a fixed dose of cisplatin, the pharmacokinetics (PKs) and...

journal_title：British journal of cancer

authors： Boven E,Westerman M,van Groeningen CJ,Verschraagen M,Ruijter R,Zegers I,van der Vijgh WJ,Giaccone G

更新日期：2005-05-09 00:00:00

abstract：BACKGROUND:Epigenetic silencing by promoter methylation and chromatin remodelling affects hundreds of genes and is a causal event for lung cancer. Treatment of patients with low doses of the demethylating agent 5-azacytidine in combination with the histone deacetylase inhibitor entinostat has yielded clinical responses...

journal_title：British journal of cancer

authors： Reed MD,Tellez CS,Grimes MJ,Picchi MA,Tessema M,Cheng YS,March TH,Kuehl PJ,Belinsky SA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The prognosis of squamous cell carcinoma of the oral tongue is poor and it would be beneficial to find prognostic markers to better adjust treatment. Bmi-1 controls cell cycle and self-renewal of tissue stem cells, transcription factor c-myc affects cell proliferation and apoptosis, and Snail regulates epith...

journal_title：British journal of cancer

authors： Häyry V,Mäkinen LK,Atula T,Sariola H,Mäkitie A,Leivo I,Keski-Säntti H,Lundin J,Haglund C,Hagström J

更新日期：2010-03-02 00:00:00

abstract：BACKGROUND:Childhood cancer survival estimates from developing nations are rare. METHODS:Using the US SEER and the Manila and Rizal Cancer Registry databases in the Philippines, 5-year survival for childhood leukaemia and lymphoma in 2001-2005 among Asian Americans were compared with both Filipinos and Caucasians in t...

journal_title：British journal of cancer

authors： Redaniel MT,Laudico A,Mirasol-Lumague MR,Alcasabas AP,Pulte D,Brenner H

更新日期：2010-06-29 00:00:00

abstract：:The establishment and characterisation (morphology, ultrastructure, tumourigenicity) of six cell lines from primary human colorectal adenocarcinomas is described. These lines were established from surgical specimens, from 49 unselected patients, without the use of 'feeder' cells, 'conditioned' medium or passage of cel...

journal_title：British journal of cancer

authors： Kirkland SC,Bailey IG

更新日期：1986-06-01 00:00:00

abstract：:Between 1980 and 1985, 914 patients with head and neck squamous cell carcinoma underwent lymph node dissection in our institution. The prognostic value of clinical factors has already been reported (Mamelle et al, 1994, Am J Surg 168: 494-498). We present here a comparison of biological characteristics of pharyngeal t...

journal_title：British journal of cancer

authors： Guerry M,Vabre L,Talbot M,Mamelle G,Leridant AM,Hill C,Bosq J,Luboinski B,Janot F

更新日期：1998-06-01 00:00:00

abstract：:Spontaneous and radiation-induced genetic instability of peripheral blood mononuclear cells derived from unselected breast cancer (BC) patients (n=50) was examined using the single-cell gel electrophoresis (Comet) assay and a modified G2 micronucleus (MN) test. Cells from apparently healthy donors (n=16) and from canc...

journal_title：British journal of cancer

authors： Djuzenova CS,Mühl B,Fehn M,Oppitz U,Müller B,Flentje M

更新日期：2006-04-24 00:00:00

abstract：:The clinical formulation of the anti-tumour agent Taxol involves the use of a mixture of ethanol and Cremophor EL. Gel electrophoresis and density-gradient ultracentrifugation were used to detect effects of Taxol infusions on serum lipoproteins. Use of the Cremophor vehicle results in a decrease in the electrophoretic...

journal_title：British journal of cancer

authors： Sykes E,Woodburn K,Decker D,Kessel D

更新日期：1994-09-01 00:00:00

abstract：:Mediastinal masses include a wide variety of tumours and remain an interesting diagnostic challenge for radiologist. We performed positron emission tomography (PET) studies of primary mediastinal tumours in order to predict the malignancy of these tumours preoperatively. Twenty-two patients with primary mediastinal tu...

journal_title：British journal of cancer

authors： Kubota K,Yamada S,Kondo T,Yamada K,Fukuda H,Fujiwara T,Ito M,Ido T

更新日期：1996-04-01 00:00:00

abstract：:The ESPAC-1, ESPAC-1 plus, and early ESPAC-3(v1) results (458 randomized patients; 364 deaths) were used to estimate the effectiveness of adjuvant 5FU/FA vs resection alone for pancreatic cancer using meta-analysis. The pooled hazard ratio of 0.70 (95% CI=0.55-0.88) P=0.003, and the median survival of 23.2 (95% CI=20....

journal_title：British journal of cancer

authors： Neoptolemos JP,Stocken DD,Tudur Smith C,Bassi C,Ghaneh P,Owen E,Moore M,Padbury R,Doi R,Smith D,Büchler MW

更新日期：2009-01-27 00:00:00

abstract：:The phenotypic expression of cells derived from human anaplastic astrocytomas, rat glioma, normal human adult and foetal brain tissue have been examined for differentiated and malignancy-associated properties. Glial fibrillary acidic protein (GFAP), high affinity glutamate and gamma-amino butyric acid (GABA) uptake an...

journal_title：British journal of cancer

authors： Frame MC,Freshney RI,Vaughan PF,Graham DI,Shaw R

更新日期：1984-03-01 00:00:00

abstract：:The combination effect of docetaxel and capecitabine on tumour response rate and survival was demonstrated recently in metastatic breast cancer patients. This combination was based on an experimental hypothesis that taxane can increase tumour sensitivity to the effect of capecitabine through the upregulation of thymid...

journal_title：British journal of cancer

authors： Toi M,Bando H,Horiguchi S,Takada M,Kataoka A,Ueno T,Saji S,Muta M,Funata N,Ohno S

更新日期：2004-06-14 00:00:00

abstract：BACKGROUND:Joint effects of mammographic density and other risk factors on breast cancer risk remain unclear. METHODS:From The Singapore Breast Screening Project, we selected 491 cases and 982 controls. Mammographic density was measured quantitatively. Data analysis was by conditional logistic regression. RESULTS:Den...

journal_title：British journal of cancer

authors： Wong CS,Lim GH,Gao F,Jakes RW,Offman J,Chia KS,Duffy SW

更新日期：2011-03-01 00:00:00