Abstract：
BACKGROUND:This study was conducted to assess the efficacy and incidence of side effects of a regimen of repeated doses of 400 microg sublingual misoprostol for termination of pregnancy of <7 weeks gestation. METHOD:Fifty women were given 400 microg sublingual misoprostol every 3 h for three doses. Two additional doses were given if necessary. RESULTS:Forty-three women (86%) had a complete abortion. Two women (4%) had incomplete abortion and 5 (10%) had an ongoing pregnancy. The median interval between the first dose of misoprostol and the passage of tissue mass was 14.1 h (3.25-561.6 h). The median duration of vaginal bleeding was 20 days (8-85 days). Side effects were mild and there was no significant drop in hemoglobin level. CONCLUSIONS:Our preliminary results on sublingual misoprostol show that it is a promising method for medical termination of pregnancy of <7 weeks. It may be used as an alternative for women who do not want surgical evacuation and who live in an area where mifepristone is not available.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Cheung W,Tang OS,Lee SW,Ho PCdoi
10.1016/s0010-7824(03)00134-3subject
Has Abstractpub_date
2003-08-01 00:00:00pages
97-9issue
2eissn
0010-7824issn
1879-0518pii
S0010782403001343journal_volume
68pub_type
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