A comparison of tamoxifen and misoprostol to misoprostol alone for early pregnancy termination.

Abstract:

:A study was undertaken to determine whether the combination of oral tamoxifen and moistened misoprostol administered vaginally was superior to that of placebo and moistened misoprostol administered vaginally for elective termination of early pregnancies.A clinical trial was conducted with a study group of 150 healthy women with pregnancies of

journal_name

Contraception

journal_title

Contraception

authors

Jain JK,Meckstroth KR,Park M,Mishell DR Jr

doi

10.1016/s0010-7824(99)00105-5

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

353-6

issue

6

eissn

0010-7824

issn

1879-0518

pii

S0010-7824(99)00105-5

journal_volume

60

pub_type

临床试验,杂志文章,随机对照试验
  • Vaginal misoprostol compared with vaginal gemeprost in termination of second trimester pregnancy. A randomized trial.

    abstract::A prospective randomized trial was conducted in 140 women to compare the efficacy of vaginal gemeprost with vaginal misoprostol for termination of second trimester pregnancy. Women requesting termination of second trimester pregnancy were randomized into two groups. Group A women were given 1 mg vaginal gemeprost ever...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0010-7824(98)00099-7

    authors: Wong KS,Ngai CS,Wong AY,Tang LC,Ho PC

    更新日期:1998-10-01 00:00:00

  • Mode of long-term antifertility effect of intrauterine neem treatment (IUNT).

    abstract::The mode of antifertility action of intrauterine neem treatment (IUNT) was studied. The effect of IUNT on ovarian functions and uterine responsiveness to ovarian hormones was examined in adult Wistar rats. The treated animals had normal reproductive cycles as indicated by the vaginal smears; serum progesterone levels ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(95)00018-6

    authors: Kaushic C,Upadhyay S

    更新日期:1995-03-01 00:00:00

  • Kinetics of bromhexine-mediated down-regulation of focal adhesive molecules of uterus and trophectoderm affecting conception in the rat.

    abstract:PURPOSE:Quantitative evaluation of properties of bromhexine (B) for expression of uterine proteins in ovariectomized (OVX) and pregnant rats. MATERIALS AND METHODS:Expression of proteins through SDS-PAGE, along with incorporation of glycosidic moieties, was conducted in pregnant and OVX rats under B influence. These f...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2005.11.006

    authors: Singh N,Malaviya B

    更新日期:2006-06-01 00:00:00

  • Interaction between phenytoin and norethisterone in the rhesus monkey.

    abstract::The effects of phenytoin treatment on plasma concentrations of norethisterone (NET) was studied in 7 healthy female rhesus monkeys. Before phenytoin treatment was started each monkey received an oral dose of 0.5 mg NET and 2 weeks later the same dose was given intravenously. On both occasions, plasma concentrations of...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(83)80021-3

    authors: Barkfeldt JO,Odlind V,Victor A

    更新日期:1983-04-01 00:00:00

  • Effects of combined oral contraceptive steroids on pituitary-ovarian function during the menstrual cycle of lactating women.

    abstract::The object of this study was to investigate the effects of combined oral contraceptives on pituitary-ovarian function during the menstrual cycle of lactating women whose prolactin levels were usually elevated. Five of six lactating women studied were considered to have the normal menstrual cycle which was comparable t...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(83)90008-2

    authors: Ryu K,Yu HK,Kwak HM,Hong SS

    更新日期:1983-03-01 00:00:00

  • Efficacy and safety of medical abortion using mifepristone and buccal misoprostol through 63 days.

    abstract:OBJECTIVE:The aim of this study was to report on the safety and efficacy of an evidence-based medical abortion regimen utilizing 200 mg of mifepristone orally followed by home use of 800 mcg misoprostol buccally 24-48 h later through 63 days estimated gestational age. STUDY DESIGN:We analyzed outcomes in women present...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2015.01.005

    authors: Gatter M,Cleland K,Nucatola DL

    更新日期:2015-04-01 00:00:00

  • Effect of a once weekly oral contraceptive upon gonadotrophin and gonadal steroid levels.

    abstract::A moderately effective oral progestogen contraceptive, R-2323 (13beta-ethyl-17alpha-ethynyl-17-hydroxy-gona-4,9,11-trien,3-one), was administered weekly in doses of 2.5 mg and 5 mg to 5 subjects each for 8 weeks. In 2 of the 10 treatment cycles of 2.5 mg and 4 of the 10 treatment cycles of 5 mg, progesterone levels i...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(74)90071-7

    authors: Tredway DR,Mishell DR Jr

    更新日期:1974-08-01 00:00:00

  • Transdermal delivery of steroids.

    abstract::The advantages of delivering drugs through the skin for systemic therapy have been widely recognized and represent a growing sector in drug development. Transdermal delivery of steroids is also a rapidly expanding field and in various clinical situations where hormonal replacement therapy is needed this route of admin...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/0010-7824(89)90012-7

    authors: Sitruk-Ware R

    更新日期:1989-01-01 00:00:00

  • "We have to what?": lessons learned about engaging support staff in an interprofessional intervention to implement MVA for management of spontaneous abortion.

    abstract:BACKGROUND:Including support staff in practice change initiatives is a promising strategy to successfully implement new reproductive health services. The Resident Training Initiative in Miscarriage Management (RTI-MM) is an intervention designed to facilitate implementation of manual vacuum aspiration (MVA) for managem...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2013.06.007

    authors: Darney BG,VanDerhei D,Weaver MR,Stevens NG,Prager SW

    更新日期:2013-08-01 00:00:00

  • A survey of prescribing habits for high-estrogen oral contraceptives.

    abstract::A simple survey was made of health-care providers to determine their attitudes toward oral contraceptives containing more than 50 mcg of estrogen. It was found that about two-thirds of respondents prescribe this group of medication, although few do so regularly. Their use seemed correlated with providers 40 years of a...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(88)90159-x

    authors: Grossman RA

    更新日期:1988-11-01 00:00:00

  • Bleeding patterns with the levonorgestrel-releasing intrauterine system when used for heavy menstrual bleeding in women without structural pelvic pathology: a pooled analysis of randomized controlled studies.

    abstract:BACKGROUND:The study was conducted to characterize the changes in bleeding pattern over time in women receiving the levonorgestrel-releasing intrauterine system (LNG-IUS) for heavy menstrual bleeding (HMB). The reduction in menstrual blood loss volume has been well documented elsewhere. STUDY DESIGN:Post hoc pooled an...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2012.08.022

    authors: Jensen J,Mansour D,Lukkari-Lax E,Inki P,Burock K,Fraser IS

    更新日期:2013-01-01 00:00:00

  • Safety evaluation of a male injectable antifertility agent, styrene maleic anhydride, in rats.

    abstract::Injection of a polymer, styrene maleic anhydride (SMA), into the lumen of the vas deferens of rats, was observed to have effective and reversible contraception. The safety evaluation of the polymer, for 90 days, was carried out in Charles Foster male rats. There have been no significant changes in any of the toxicity ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(89)80010-1

    authors: Sethi N,Srivastava RK,Singh RK

    更新日期:1989-02-01 00:00:00

  • Use of hCG stimulation test in women immunized with beta-hCG vaccine.

    abstract::Eleven normally menstruating women, who had earlier been immunized with NII beta-hCG vaccine but had no detectable anti-hCG antibody titres, were selected as controls for the hCG challenge test using 1000/2000 I.U. The test was repeated in five of them after a booster immunization, which raised antibody titres to 18-4...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/0010-7824(91)90035-e

    authors: Shahani SM,Patel KL

    更新日期:1991-10-01 00:00:00

  • Comparative effects of Lunelle monthly contraceptive injection (medroxyprogesterone acetate and estradiol cypionate injectable suspension) and ortho-Novum 7/7/7 oral contraceptive (norethindrone/ethinyl estradiol triphasic) on lipid profiles. Investigator

    abstract::As part of a 60-week, open-label, nonrandomized, parallel, controlled study comparing a monthly contraceptive injection containing medroxyprogesterone acetate (MPA) 25 mg and estradiol cypionate (E(2)C) 5 mg (Lunelle Monthly Contraceptive Injection) and a norethindrone 0.5, 0.75, 1.0 mg/0.035 mg ethinyl estradiol (NET...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0010-7824(99)00114-6

    authors: Cromie MA,Maile MH,Wajszczuk CP

    更新日期:2000-01-01 00:00:00

  • Subcutaneous DMPA vs. intramuscular DMPA: a 2-year randomized study of contraceptive efficacy and bone mineral density.

    abstract:BACKGROUND:A formulation of depot medroxyprogesterone acetate (DMPA) has been developed that allows subcutaneous injection (104 mg/0.65 mL; DMPA-SC) and achieves highly effective contraception with a similar tolerability profile to intramuscular DMPA (150 mg/mL; DMPA-IM). STUDY DESIGN:This randomized, evaluator-blinde...

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.contraception.2009.02.005

    authors: Kaunitz AM,Darney PD,Ross D,Wolter KD,Speroff L

    更新日期:2009-07-01 00:00:00

  • Early follicular phase luteinizing hormone-releasing hormone agonist administration - effects on follicular maturation and corpus luteum function in women.

    abstract::The potent luteinizing hormone-releasing hormone (LRH) agonist D-Ser(TBU)6-EA10-LRH was administered in a daily subcutaneous dose of 5 or 25 microgram for 1, 3 or 5 consecutive days to twelve regularly menstruating women in the early follicular phase of the menstrual cycle in an attempt to disturb follicular maturatio...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(82)90016-6

    authors: Skarin G,Nillius SJ,Wide L

    更新日期:1982-01-01 00:00:00

  • Post-operative discomfort after ring or clip tubal ligation--is there any difference and do indomethacin suppositories help?

    abstract::One-hundred patients undergoing Falope ring or clip laparoscopic tubal ligation were given either a placebo or a 100 mg indomethacin rectal suppository one hour pre-operatively. Treatment was randomised and double-blind. Post-operative analgesic requirements and side effects were monitored. Forty-seven patients receiv...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(90)90018-q

    authors: MacLennan AH,Rodrigues LV,Krutli DR,Klomp A

    更新日期:1990-09-01 00:00:00

  • Tamoxifen as an antifertility agent in the long-tailed macaque (Macaca fascicularis).

    abstract::The potential use of tamoxifen, a nonsteroidal antiestrogen, as an antifertility agent was studied in the long-tailed macaque (Macaca fascicularis). Twenty-six cycling females were bred, then treated with a single oral dose of tamoxifen (5 mg/kg) (N = 13) or vehicle (N = 13) on day 4 post-ovulation. Serum progesterone...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(93)90047-b

    authors: Tarantal AF,Hendrickx AG,Matlin SA,Lasley BL,Gu QQ,Thomas CA,Vince PM,Van Look PF

    更新日期:1993-03-01 00:00:00

  • Modification of oral contraceptive relationships on breast cancer risk by selected factors among younger women.

    abstract::In a case-control study of 1647 breast cancer cases and 1501 population controls under 45 years of age, potential modifying effects of other risk factors on the relationship of oral contraceptives to breast cancer were examined. Among the total series of study subjects, the relationship of extended pill usage was grea...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(97)00012-7

    authors: Brinton LA,Gammon MD,Malone KE,Schoenberg JB,Daling JR,Coates RJ

    更新日期:1997-04-01 00:00:00

  • Women's knowledge of their state's abortion regulations. A national survey.

    abstract:OBJECTIVES:States vary significantly in their regulation of abortion. Misinformation about abortion is pervasive and propagated by state-mandated scripts that contain abortion myths. We sought to investigate women's knowledge of abortion laws in their state. Our secondary objective was to describe women's ability to di...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2020.08.001

    authors: Swartz JJ,Rowe C,Morse JE,Bryant AG,Stuart GS

    更新日期:2020-11-01 00:00:00

  • Progestogen-only contraceptive use among breastfeeding women: a systematic review.

    abstract:BACKGROUND:The use of progestogen-only contraceptives by breastfeeding women raises theoretical concerns regarding possible adverse effects on breastfeeding success, and infant health or growth. This review was conducted to determine from the literature whether use of progestogen-only contraceptives by breastfeeding wo...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2010.02.002

    authors: Kapp N,Curtis K,Nanda K

    更新日期:2010-07-01 00:00:00

  • Therapeutic abortion in early pregnancy with antiprogestogen RU486 alone or in combination with prostaglandin analogue (gemeprost).

    abstract::Abortion was attempted in 39 women in early pregnancy (less than 56 days amenorrhea) with the progesterone antagonist RU486 alone (150 mg per day for 4 days) or in combination with a PG analogue, 16,16-dimethyl-trans-delta 2-PGE1 (Gemeprost) in the form of a 1 mg vaginal pessary. Complete abortion was also attempted i...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(86)90055-7

    authors: Cameron IT,Michie AF,Baird DT

    更新日期:1986-11-01 00:00:00

  • Standardizing the classification of abortion incidents: the Procedural Abortion Incident Reporting and Surveillance (PAIRS) Framework.

    abstract:OBJECTIVES:To develop and validate standardized criteria for assessing abortion-related incidents (adverse events, morbidities, near misses) for first-trimester aspiration abortion procedures and to demonstrate the utility of a standardized framework [the Procedural Abortion Incident Reporting & Surveillance (PAIRS) Fr...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2017.05.004

    authors: Taylor D,Upadhyay UD,Fjerstad M,Battistelli MF,Weitz TA,Paul ME

    更新日期:2017-07-01 00:00:00

  • Contraceptive efficacy of lactational amenorrhea in urban Chilean women.

    abstract::The contraceptive efficacy of breastfeeding was assessed in 236 healthy urban women who were followed at monthly intervals during the first postpartum year. Proportional hazard models were used to evaluate the influence of time postpartum, menstrual status and breastfeeding pattern upon the risk of pregnancy. Time and...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(91)90072-n

    authors: Díaz S,Aravena R,Cárdenas H,Casado ME,Miranda P,Schiappacasse V,Croxatto HB

    更新日期:1991-04-01 00:00:00

  • How women anticipate coping after an abortion.

    abstract:BACKGROUND:There has been some study of women's emotional and psychological well-being after an abortion but no research into women's expectations, at the time of seeking an abortion, of how they will cope after the abortion. STUDY DESIGN:We abstracted counseling needs assessment forms of 5109 women who sought an abor...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2011.11.002

    authors: Foster DG,Gould H,Kimport K

    更新日期:2012-07-01 00:00:00

  • Studies on mechanism(s) of antifertility action of gossypol in rat and hamster.

    abstract::This study was undertaken with a view to investigate the possible mechanism(s) of antifertility action of gossypol acetate in rats and hamsters. Adult male rats were treated by gavage with 30 mg/kg/day of gossypol for 7 weeks and adult male hamsters were treated similarly with 20 mg/kg/day gossypol for 8 weeks. The tr...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(89)90066-8

    authors: Srivastava A,Gupta G,Setty BS

    更新日期:1989-03-01 00:00:00

  • Women's perceptions and treatment patterns related to contraception: results of a survey of US women.

    abstract:OBJECTIVES:The aim of this survey was to understand US women's contraception journey from her first prescribed method to her current one including reasons for choosing and stopping/switching methods, healthcare provider relationships, and bleeding preferences. STUDY DESIGN:We administered a nationally-representative, ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2017.09.010

    authors: Nelson AL,Cohen S,Galitsky A,Hathaway M,Kappus D,Kerolous M,Patel K,Dominguez L

    更新日期:2018-03-01 00:00:00

  • Two randomized controlled trials comparing the Hulka and Filshie Clips for tubal sterilization.

    abstract::To compare the effectiveness and safety of the Filshie Clip System and Hulka Clip System when applied via minilaparotomy and laparoscopy, we conducted 2 multicenter randomized controlled trials of 2126 women (878 in the minilaparotomy study and 1248 in the laparoscopy study) who received either the Filshie or Hulka Cl...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0010-7824(00)00166-9

    authors: Dominik R,Gates D,Sokal D,Cordero M,Lasso de la Vega J,Remes Ruiz A,Thambu J,Lim D,Louissaint S,Galvez RS,Uribe L,Zighelboim I

    更新日期:2000-10-01 00:00:00

  • A comparison of contraceptive procurement pre- and post-benefit change.

    abstract:BACKGROUND:In 2002, the Kaiser Foundation Health Plan in California changed its coverage policy to include 100% universal coverage for the most effective forms of contraception and for emergency contraceptive pills (ECPs). This study sought to evaluate whether removing the cost of contraception as a potential barrier t...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2007.07.006

    authors: Postlethwaite D,Trussell J,Zoolakis A,Shabear R,Petitti D

    更新日期:2007-11-01 00:00:00

  • Use of a radioreceptor test for HCG in women practicing contraception.

    abstract::The importance of a simple, rapid and highly sensitive test for the diagnosis of early pregnancy cannot be overemphasized. In the present times when newer delivery systems of contraceptive agents and menstrual regulation procedures are increasingly used for fertility regulation, it is inevitable that confirmation of e...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(78)90039-2

    authors: Shahani SM,Kulkarni PP,Patel KL

    更新日期:1978-11-01 00:00:00