Use of a radioreceptor test for HCG in women practicing contraception.

Abstract:

:The importance of a simple, rapid and highly sensitive test for the diagnosis of early pregnancy cannot be overemphasized. In the present times when newer delivery systems of contraceptive agents and menstrual regulation procedures are increasingly used for fertility regulation, it is inevitable that confirmation of early pregnancy poses a severe problem. This radioreceptor test has been found to be very reliable even in early cases. A positive test was 100% accurate for pregnancy whereas the accuracy of a negative test was found to be 94.4%. Confirmation of these results was done by various other parameters like clinical, histological, radioimmunoassay for HCG and biological test for pregnancy. :An evaluation of a radioreceptor assay (RRA) for detection of early pregnancy is reported. Following delayed or irregular periods, 250 women were tested using the RRA. The test requires only .1 ml of plasma and the results are obtained within 2 hours. There were 179 positive tests, all of which were confirmed by other methods to be 100% accurate. The test was given to all but 7 of the patients within 2 weeks of the missed period. It is concluded that the RRA is more sensitive than most other immunological tests and less time-consuming than the radioimmunoassay.

journal_name

Contraception

journal_title

Contraception

authors

Shahani SM,Kulkarni PP,Patel KL

doi

10.1016/0010-7824(78)90039-2

subject

Has Abstract

pub_date

1978-11-01 00:00:00

pages

543-50

issue

5

eissn

0010-7824

issn

1879-0518

pii

0010-7824(78)90039-2

journal_volume

18

pub_type

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