Abstract:
:International efforts are underway that aim at determining the complete genome sequence of the social amoeba Dictyostelium discoideum. As strategy, a whole chromosome shotgun (WCS) approach was chosen and each of the six Dictyostelium chromosomes was assigned to project partners. The project is well advanced, chromosome 2 was recently published, and it is expected that the sequences of chromosomes 1 and 6 and a gene catalogue for the complete genome will be available at the end of this year. The genome sequence, together with powerful molecular genetic tools, will undoubtedly further accelerate Dictyostelium research into a number of fundamental biological processes that are common to a wide range of eukaryotes. Furthermore, it will constitute the basis for genome-wide functional analyses. The integration of results from these studies should ultimately lead to a better understanding of the complex networks that govern cellular behavior and development.
journal_name
Curr Genetjournal_title
Current geneticsauthors
Eichinger Ldoi
10.1007/s00294-003-0416-1subject
Has Abstractpub_date
2003-11-01 00:00:00pages
59-72issue
2eissn
0172-8083issn
1432-0983journal_volume
44pub_type
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