Inhalation challenge with bovine dander allergens: who needs it?

abstract：:The adult respiratory distress syndrome (ARDS) is a devastating clinical illness characterized by refractory hypoxemia and high-permeability pulmonary edema. Reactive oxygen species such as hydrogen peroxide and hypochlorous acid may play a key role in the pathogenesis of the acute lung injury. Glutathione (GSH) is a ...

journal_title：Chest

authors： Pacht ER,Timerman AP,Lykens MG,Merola AJ

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:We tested the hypothesis that an increase in the blood colloid osmotic pressure (COP) that is maintained during early-stage endotoxemia may decrease fluid flux across capillaries and may reduce pulmonary and multiple-organ edema. DESIGN:Prospective study. SETTINGS:Research laboratory in a hospital. SUBJEC...

journal_title：Chest

authors： Camacho MT,Totapally BR,Torbati D,Wolfsdorf J

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:We evaluated the association between hemodynamic parameters of chronic congestive heart failure (CHF) and mediastinal lymphadenopathy (MLA) in heart transplantation (HT) candidates and the effect of HT on MLA. We also described the results of lymph node (LN) biopsies of MLA in the patients. METHODS:Patients...

journal_title：Chest

authors： Pastis NJ Jr,Van Bakel AB,Brand TM,Ravenel JG,Gilbert GE,Silvestri GA,Judson MA

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension, which is related to right ventricular (RV) failure, indicates a poor prognosis in heart failure (HF). Increased ventilatory response and exercise oscillatory ventilation (EOV) also have a negative impact. We hypothesized that the severity classification of HF and risk prediction could...

journal_title：Chest

authors： Guazzi M,Naeije R,Arena R,Corrà U,Ghio S,Forfia P,Rossi A,Cahalin LP,Bandera F,Temporelli P

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To determine the contribution of the various components of a rehabilitation program to the improvement of exercise capacity and health-related quality of life (HRQL) in patients with COPD. DATA SOURCES:MEDLINE (1966 to April 1996) was searched. Abstracts presented at international conferences were also hand ...

journal_title：Chest

authors： Lacasse Y,Guyatt GH,Goldstein RS

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous administration of aerosolized beta 2-agonists has been suggested as an effective treatment for severe reversible airways disease. To facilitate continuous therapy and avoid a feed system for small-volume nebulizers (SVNs), a large-volume medication nebulizer (Vortran HEART) was deve...

journal_title：Chest

authors： McPeck M,Tandon R,Hughes K,Smaldone GC

更新日期：1997-05-01 00:00:00

abstract：:To determine work-of breathing with continuous positive airway pressure (CPAP) delivery systems, we used a lung model to simulate spontaneous breathing. "Additional work" during tidal breathing was derived by comparing change in airway pressure with change in tidal volume. Seven demand-flow CPAP delivery systems were ...

journal_title：Chest

authors： Katz JA,Kraemer RW,Gjerde GE

更新日期：1985-10-01 00:00:00

abstract：KEY POINTS:1. Historically, medical ethics focused on the proper conduct of physicians as members of a profession. 2. Bioethics has emerged as a distinct field over the past several decades and has a broader scope than traditional medical ethics. The field of bioethics includes research ethics, public health ethics, or...

journal_title：Chest

authors： Carrese JA,Sugarman J

更新日期：2006-12-01 00:00:00

abstract：:Men who snore heavily have an increased incidence of hypertension, angina, stroke, and neuropsychologic dysfunction, which may be due to nocturnal oxygen desaturation. Nocturnal oxygen therapy might be beneficial to such individuals by improving oxygenation and relieving tissue hypoxia. Twenty-eight asymptomatic heavy...

journal_title：Chest

authors： Block AJ,Hellard DW,Cicale MJ

更新日期：1987-09-01 00:00:00

abstract：:Random assessments of SaO2 were performed via pulse oximetry in 274 hospitalized non-ICU patients prescribed supplemental O2 in a large tertiary care university hospital. In 507 assessments performed in patients inspiring the prescribed O2, 426 were receiving excessive amounts of O2 to maintain a SaO2 > or = 92 percen...

journal_title：Chest

authors： Albin RJ,Criner GJ,Thomas S,Abou-Jaoude S

更新日期：1992-12-01 00:00:00

abstract：:The severity of pulmonary hypertension was evaluated by right cardiac catheterization in 89 patients with stable chronic obstructive pulmonary disease, both at rest and during maximum treadmill exercise. Thirty-one patients were found to have pulmonary hypertension at rest, defined as a mean pulmonary arterial pressur...

journal_title：Chest

authors： Keller CA,Shepard JW Jr,Chun DS,Vasquez P,Dolan GF

更新日期：1986-08-01 00:00:00

abstract：CASE PRESENTATION:A 38-year-old man of Indian origin, who migrated to Greece 13 years prior to presentation, was admitted to our hospital with a 2-month history of nonprogressive, intermittent (mostly evening), low-grade (up to 38.5°C) fever, accompanied by night sweats, dry cough, mild dyspnea on exertion (modified Me...

journal_title：Chest

authors： Papadopoulos D,Nakou A,Lymperopoulos K,Filaditaki V

更新日期：2018-10-01 00:00:00

abstract：:Forty-eight elderly patients with uncomplicated mild essential hypertension entered two drug regimens. In group 1, clonidine monotherapy (n = 15), clonidine was titrated to achieve goal blood pressure (less than 90 mm Hg diastolic) in dosages of 0.05 mg twice daily to 0.2 mg three times daily. Blood pressure decreased...

journal_title：Chest

authors： Thananopavarn C,Golub MS,Sambhi MP

更新日期：1983-02-01 00:00:00

abstract：:Adults with CF followed in a university center were assessed for the presence of the most common CF gene mutation, delta-F508. Excluding one member of a sibling pair, 29 of 55 subjects had two copies of delta-F508 (homozygotes), 23 had one copy of delta-F508 with the other CF mutation not identified (complex heterozyg...

journal_title：Chest

authors： Burke W,Aitken ML,Chen SH,Scott CR

更新日期：1992-08-01 00:00:00

abstract：:A patient with systemic artery-to-pulmonary artery fistulae is described. Historically, all therapy of this type of lesion has been surgical. We describe a new mode of treatment, therapeutic embolization, which obviates surgical intervention and its attendant risks. Embolization is an alternative to surgery that shoul...

journal_title：Chest

authors： Wolf DC,Wurtzbacher JJ,Horton J

更新日期：1982-12-01 00:00:00

abstract：:Human lung mast cells have been reported recently to contain small amounts of the elastolytic protease present in the neutrophil and implicated in the pathogenesis of alveolar wall destruction in emphysema. Since mast cells are numerous within alveolar walls, release of inflammatory mediators (and possibly elastase) b...

journal_title：Chest

authors： Kalenderian R,Raju L,Roth W,Schwartz LB,Gruber B,Janoff A

更新日期：1988-07-01 00:00:00

abstract：:A patient with the sick sinus syndrome accompanying mirror-image dextrocardia which was associated with double superior venae cavae and an absent inferior vena cava is presented. A permanent transvenous demand pacemaker was inserted because of repeated episodes of dizziness and a documented 31/2-second period of asyst...

journal_title：Chest

authors： Goyal SL,Lichestein E,Gupta PK,Chadda KD,Lajam F

更新日期：1976-04-01 00:00:00

abstract：:Sacrococcygeal teratoma is rarely diagnosed in adults. Pulmonary mass as the presenting clinical form of the malignant variety of this germ-cell tumor is exceptional. We report herein such a case with the noticeable peculiarity of showing the air meniscus sign on chest roentgenographic examination. ...

journal_title：Chest

authors： Roig J,Aguilar X,Maestre J,Domingo C,Morera J

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:In addition to affecting the oxygen supply to the brain, pulmonary function is a marker of multiple insults throughout life (including smoking, illness, and socioeconomic deprivation). In this meta-analysis of existing longitudinal studies, the hypothesis that lower pulmonary function and respiratory illness...

journal_title：Chest

authors： Russ TC,Kivimäki M,Batty GD

更新日期：2020-06-01 00:00:00

abstract：:This article addresses two basic questions about ethics committees: why we have them, and how they might be helpful to clinicians. Our answer to the first question is twofold. First, we suggest that legal, regulatory, and professional forces drove the development of ethics committees, particularly as an alternative to...

journal_title：Chest

authors： Aulisio MP,Arnold RM

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and management of severe sepsis. We investigated the impact of one to two PCT determinations on ICU day 1 on health-care utilization and cost in a large research database. METHODS:A retrospective, propensity score-matched multivariabl...

journal_title：Chest

authors： Balk RA,Kadri SS,Cao Z,Robinson SB,Lipkin C,Bozzette SA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Mucosa-associated lymphoid tissue (MALT) lymphoma constitutes approximately 90% of primary pulmonary lymphoma, and the diagnosis of pulmonary MALT lymphoma often requires invasive methods such as surgical lung biopsy. Chromosomal rearrangements involving MALT lymphoma translocation gene 1 (MALT1) have been r...

journal_title：Chest

authors： Kido T,Yatera K,Noguchi S,Sakurai Y,Nagata S,Kozaki M,Tokuyama S,Ogoshi T,Kawanami T,Yoshii C,Mukae H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Failure to reliably diagnose ARDS may be a major driver of negative clinical trials and underrecognition and treatment in clinical practice. We sought to examine the interobserver reliability of the Berlin ARDS definition and examine strategies for improving the reliability of ARDS diagnosis. METHODS:Two hu...

journal_title：Chest

authors： Sjoding MW,Hofer TP,Co I,Courey A,Cooke CR,Iwashyna TJ

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a highly prevalent disorder that has been associated with an increased risk for cardiovascular morbidity, even in children. However, not all children with OSA manifest alterations in endothelial postocclusive hyperemia, an endothelial nitric oxide synthase (eNOS)-dependent re...

journal_title：Chest

authors： Kheirandish-Gozal L,Khalyfa A,Gozal D,Bhattacharjee R,Wang Y

更新日期：2013-04-01 00:00:00

abstract：:Recurrent pericardial effusion or tamponade can complicate malignant disease. The medical approach with pharmacologic agents has a high recurrence rate. Balloon pericardiotomy (BP) may provide a less invasive alternative to surgery. We performed BP in ten high-risk patients with malignant pericardial tamponade (MPT). ...

journal_title：Chest

authors： Galli M,Politi A,Pedretti F,Castiglioni B,Zerboni S

更新日期：1995-12-01 00:00:00

abstract：STUDY OBJECTIVES:Poor dental hygiene has been linked to respiratory pathogen colonization in residents of long-term care facilities. We sought to investigate the association between dental plaque (DP) colonization and lower respiratory tract infection in hospitalized institutionalized elders using molecular genotyping....

journal_title：Chest

authors： El-Solh AA,Pietrantoni C,Bhat A,Okada M,Zambon J,Aquilina A,Berbary E

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Patients with acute respiratory symptoms still remain a diagnostic challenge. The aim of the study was to evaluate whether focused sonography could potentially diagnose life-threatening conditions missed at the primary assessment in a patient population consisting of admitted patients with acute respiratory ...

journal_title：Chest

authors： Laursen CB,Sloth E,Lambrechtsen J,Lassen AT,Madsen PH,Henriksen DP,Davidsen JR,Rasmussen F

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-7 was reported to be a key molecule in the pathogenesis of idiopathic pulmonary fibrosis (IPF) based on the result of microarray analysis and knockout mice. However, the role of MMP-7 has not been determined in other types of idiopathic interstitial pneumonia (IIP). The aim of ...

journal_title：Chest

authors： Huh JW,Kim DS,Oh YM,Shim TS,Lim CM,Lee SD,Koh Y,Kim WS,Kim WD,Kim KR

更新日期：2008-05-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the accuracy of the respiratory inductive plethysmography in the measurement of PEEP-induced changes in end-expiratory lung volume during mechanical ventilation and its accuracy and stability in the measurement of ventilation during controlled mechanical ventilation and spontaneous breathing. ...

journal_title：Chest

authors： Valta P,Takala J,Foster R,Weissman C,Kinney JM

更新日期：1992-07-01 00:00:00

abstract：UNLABELLED:Formoterol solution aerosol has proved to be a fast and long-acting beta 2-sympathicomimetic drug in many clinical trials. The physical stability, however, was such that storage needed to be at 4 degrees C to 8 degrees C before first use; afterwards, the aerosol could be used for another three months at room...

journal_title：Chest

authors： Maesen FP,Nakratzas G,Bantje TA,Prins J,Zweers PG

更新日期：1992-11-01 00:00:00