Elevated histamine and tryptase levels in smokers' bronchoalveolar lavage fluid. Do lung mast cells contribute to smokers' emphysema?

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a devastating disease, yet validated, reliable criteria for evaluating patient response to therapies in clinical trials are lacking. METHODS:To optimize selection of end point criteria for the study of interferon (IFN)-gamma1b in patients with IPF, we retrospectively a...

journal_title：Chest

authors： King TE Jr,Safrin S,Starko KM,Brown KK,Noble PW,Raghu G,Schwartz DA

更新日期：2005-01-01 00:00:00

abstract：:We describe two patients with histologically proven pulmonary Langerhans' cell histiocytosis in whom radiologic improvement occurred following smoking cessation. The patients had 23- and 25-pack-year smoking histories, respectively. High-resolution CT revealed multiple small nodules, located predominantly in the upper...

journal_title：Chest

authors： Mogulkoc N,Veral A,Bishop PW,Bayindir U,Pickering CA,Egan JJ

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) pattern. This study aimed to describe the distinct clinical features of PPFE with UIP pattern compared with idiopathic pulmonary fibrosis (IPF). METHOD...

journal_title：Chest

authors： Oda T,Ogura T,Kitamura H,Hagiwara E,Baba T,Enomoto Y,Iwasawa T,Okudela K,Takemura T,Sakai F,Hasegawa Y

更新日期：2014-11-01 00:00:00

abstract：:We evaluated the feasibility of utilizing physician assistants as providers of primary care in a medical ICU. After a three-month period of rigorous training, two PAs were assigned to the ICU. Their performance as well as the operation of the ICU over a two-year period was evaluated and compared to two preceding years...

journal_title：Chest

authors： Dubaybo BA,Samson MK,Carlson RW

更新日期：1991-01-01 00:00:00

abstract：:Klippel-Trenaunay syndrome (KTS) is a congenital disorder characterized by a triad of cutaneous vascular nevi, soft tissue or bony hypertrophy, and varicose veins or venous malformations involving one or more extremities. An incidence of venous thromboembolism of up to 22% has been reported in this disorder. Also repo...

journal_title：Chest

authors： Walder B,Kapelanski DP,Auger WR,Fedullo PF

更新日期：2000-05-01 00:00:00

abstract：:A unique association of giant lymph node hyperplasia (Castleman's disease) and cardiac tamponade is presented. Although pleural effusions have been previously described with Castleman's disease, the authors believe this to be the first report of pericardial effusion and tamponade with this entity. The development of e...

journal_title：Chest

authors： Nicolosi AC,Almassi GH,Komorowski R

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:We designed and conducted this multicenter randomized active-controlled open-label trial to evaluate the efficacy of acupuncture, auricular point pressing, and nicotine replacement therapy (NRT) on tobacco cessation in the Chinese population. METHODS:This randomized controlled trial was conducted in seven h...

journal_title：Chest

authors： Wang YY,Liu Z,Wu Y,Yang L,Guo LT,Zhang HB,Yang JS,Chinese Acupuncture for Tobacco Cessation Research Team.

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine how common sleep-related desaturation with preserved awake resting pulse oximetric saturation (SpO(2)) was in a large cohort of adult cystic fibrosis (CF) patients with variable degrees of pulmonary disease. We then determined whether nocturnal desaturation could re...

journal_title：Chest

authors： Frangolias DD,Wilcox PG

更新日期：2001-02-01 00:00:00

abstract：:There are many complementary techniques for mediastinal staging of lung cancer. It is increasingly apparent that the accuracy of mediastinal staging depends not only on which test is used but also on technical factors of how the procedure is performed. This article reviews data regarding such technical factors and pro...

journal_title：Chest

authors： Detterbeck F,Puchalski J,Rubinowitz A,Cheng D

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To determine whether certain occupations and occupationally related exposures were associated with a history of sarcoidosis in African-American siblings. METHODS:We collected occupational data from 921 African Americans in 273 sibships that had been identified through a sarcoidosis case. Among the 648 sibli...

journal_title：Chest

authors： Kucera GP,Rybicki BA,Kirkey KL,Coon SW,Major ML,Maliarik MJ,Iannuzzi MC

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Lymphangioleiomyomatosis (LAM) is a destructive lung disease of women caused by proliferation of neoplastic-like LAM cells, with mutations in the TSC1/2 tumor suppressor genes. Based on case reports, levels of cancer antigen 125 (CA-125), an ovarian cancer biomarker, can be elevated in patients with LAM. We ...

journal_title：Chest

authors： Glasgow CG,Pacheco-Rodriguez G,Steagall WK,Haughey ME,Julien-Williams PA,Stylianou MP,Gochuico BR,Moss J

更新日期：2018-02-01 00:00:00

abstract：:Acute hypoxemia produces opposite effects on the pulmonary and systemic vascular resistance. To assess the influence of acute hypoxemia on cardiac murmurs, 36 patients with a single valvular or congenital heart lesion were studied. As expected from these hemodynamic effects, right-sided regurgitant type murmurs increa...

journal_title：Chest

authors： Curiel R,Tortoledo F,Rodriguez L,Soto R,Perez-Gonzalez J

更新日期：1982-02-01 00:00:00

abstract：STUDY OBJECTIVES:Small-cell lung cancer (SCLC) has an unfavorable prognosis, especially when the disease is extensive at presentation. Accurate staging procedures are therefore needed for treatment planning. Positron emission tomography (PET) is a modern noninvasive imaging technique, the value of which for the staging...

journal_title：Chest

authors： Hauber HP,Bohuslavizki KH,Lund CH,Fritscher-Ravens A,Meyer A,Pforte A

更新日期：2001-03-01 00:00:00

abstract：:An unusual case of Staphylococcus aureus endocarditis confined to the mural left atrium is presented. Echocardiographic studies revealed a 1.5 x 2.0-cm vegetation mimicking a myxoma situated in the path of a mitral regurgitant jet on a color Doppler test. Emboli to upper and lower extremities and brain complicated the...

journal_title：Chest

authors： Bierbrier GS,Novick RJ,Guiraudon C,Wisenberg G,Boughner D

更新日期：1991-03-01 00:00:00

abstract：:Serial hemodynamic alterations were investigated in seven elderly patients with heat stroke. Their mean age was 72 +/- 6 years. The circulatory response to heat stroke was either hyperdynamic of hypodynamic. Two patients had increased cardiac index (4.3 and 4.4 L/min/m2), increased right atrial pressure (10 and 12 mm ...

journal_title：Chest

authors： Sprung CL

更新日期：1979-03-01 00:00:00

abstract：:A six-month-old girl with an aberrant systemic arterial supply from the descending thoracic aorta to the left lower lobe had congestive heart failure. Although the pulmonary parenchyma was normal, there was an absence of normal pulmonary arterial supply to the left lower lobe. Main pulmonary arterial and aortic cinean...

journal_title：Chest

authors： Yabek SM,Burstein J,Berman W Jr,Dillon T

更新日期：1981-11-01 00:00:00

abstract：STUDY OBJECTIVES:The prevalence of gastroesophageal reflux disease (GERD) is higher in people with asthma than in control populations. Predisposing factors for GERD development may include asthma medications such as prednisone. The objective of this study was to determine whether prednisone alters GERD parameters in pe...

journal_title：Chest

authors： Lazenby JP,Guzzo MR,Harding SM,Patterson PE,Johnson LF,Bradley LA

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has been reported to be associated with increased values of exhaled nitric oxide (ENO), which could not be entirely explained by the association between CRS and asthma. The aim of this study was to investigate the variables associated with increased ENO in patients with CRS. MET...

journal_title：Chest

authors： Guida G,Rolla G,Badiu I,Marsico P,Pizzimenti S,Bommarito L,De Stefani A,Usai A,Bugiani M,Malinovschi A,Bucca C,Heffler E

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:This study applies a stochastic or probability search and display model to prospectively predict outcome and to evaluate therapeutic effects in a consecutively monitored series of 396 patients with severe thoracic and thoracoabdominal injuries. STUDY DESIGN:Prospective observational study of outcome predicti...

journal_title：Chest

authors： Shoemaker WC,Bayard DS,Wo CC,Chan LS,Chien LC,Lu K,Jelliffe RW

更新日期：2005-10-01 00:00:00

abstract：:Prevalence rates for asthma in various parts of the world are different and this cannot be entirely explained by differences in methodology. Low prevalence rates are found in third world countries, particularly marked for children. The reasons for these differences are obscure but are largely environmental. Some sugge...

journal_title：Chest

authors： Cookson JB

更新日期：1987-06-01 00:00:00

abstract：:The adverse effects of prolonged immobility are due primarily to gravitational effects on blood flow and ventilation, impairment of the normal mucociliary escalator and possibly an increase in extravascular lung water. However, CLRT theoretically should reverse these abnormalities. The sequence of events that culminat...

journal_title：Chest

authors： Sahn SA

更新日期：1991-05-01 00:00:00

abstract：CASE PRESENTATION:A 32-year-old man presented with fever, nonproductive cough, diffuse lymphadenopathy, and polyarticular pain for 2 weeks. His medical history included HIV diagnosed 10 years ago, anal intraepithelial neoplasia, Kaposi sarcoma, and herpes simplex virus-2 infection. The patient was not receiving antiret...

journal_title：Chest

authors： Xian JZ,Cherian SV,Golardi N,Estrada-Y-Martin RM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The study documented the emergence of new forms of resistant bacilli (totally drug-resistant [TDR] or super extensively drug-resistant [XDR] tuberculosis [TB] strains) among patients with multidrug-resistant TB (MDR-TB). METHODS:Susceptibility testing against first- and second-line drugs was performed on is...

journal_title：Chest

authors： Velayati AA,Masjedi MR,Farnia P,Tabarsi P,Ghanavi J,ZiaZarifi AH,Hoffner SE

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To describe the anatomy and neurophysiology of the cough reflex. METHODS:A review of the literature was carried out using PubMed and the ISI Web of Knowledge from 1951 to 2004. Most of the referenced studies were carried out in animals CONCLUSIONS:Studies carried out in animals provide suggestive but incon...

journal_title：Chest

authors： Canning BJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a progressive disease with high rates of morbidity and mortality. Current therapies improve symptoms, functional capacity, and, in select cases, survival. Little is known about patient factors that may predict the likelihood of patient-important, clinically relevant r...

journal_title：Chest

authors： Mathai SC,Hassoun PM,Puhan MA,Zhou Y,Wise RA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Human telomere disease consists of a wide spectrum of disorders, including pulmonary, hepatic, and bone marrow abnormalities. The extent of bone marrow and liver abnormalities in patients with interstitial lung disease (ILD) and short telomeres is unknown. METHODS:The lung transplant clinic established a pr...

journal_title：Chest

authors： George G,Rosas IO,Cui Y,McKane C,Hunninghake GM,Camp PC,Raby BA,Goldberg HJ,El-Chemaly S

更新日期：2015-06-01 00:00:00

abstract：:Neurosarcoidosis occurs in approximately 5% of patients with systemic sarcoidosis. A review of medical literature shows that intracranial mass-like lesions secondary to sarcoidosis are quite rare. CT and MRI scanning would suggest that this manifestation of neurosarcoidosis may be more common than previously realized....

journal_title：Chest

authors： Veres L,Utz JP,Houser OW

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. METHODS:The methods of this guideline f...

journal_title：Chest

authors： Linkins LA,Dans AL,Moores LK,Bona R,Davidson BL,Schulman S,Crowther M

更新日期：2012-02-01 00:00:00

abstract：:Closure of ventricular septal defects through the aortic valve annulus has been described for a variety of cardiac anomalies. This technique is most appropriate when simultaneous aortic valve replacement is anticipated. A continuous suture through the patch material may produce a purse-string effect upon the aortic va...

journal_title：Chest

authors： Stewart S

更新日期：1976-08-01 00:00:00

abstract：:From 1982 to 1989, ECD was performed on 18 patients suffering from poorly-tolerated massive pulmonary embolism, for whom classic treatments (fibrinolytics and surgery) were impossible. Eleven of these 18 patients immediately improved (S group). This procedure was unsuccessful in other seven patients (F group). Thirtee...

journal_title：Chest

authors： Timsit JF,Reynaud P,Meyer G,Sors H

更新日期：1991-09-01 00:00:00