The inescapable relevance of bioethics for the practicing clinician.

abstract：:A 41-year-old woman had progressive shortness of breath. Cerebrotendinous xanthomatosis was diagnosed 4 years before. An open-lung biopsy showed the simultaneous presence of cerebrotendinous xanthomatosis and pulmonary lymphangioleiomyomatosis. This is perhaps the first time the coincidental occurrence of these two di...

journal_title：Chest

authors： Dormans TP,Verrips A,Bulten J,Cox N

更新日期：1997-07-01 00:00:00

abstract：:Mucoepidermoid carcinoma of the trachea is rare. Its occurence in a 14-year-old boy is reported here. This case illustrates the typical course of tracheal tumors with clinical manifestations of cough, wheezing, and hemoptysis, the intially reported normal chest roentgenogram, and the common failure to diagnose trachea...

journal_title：Chest

authors： Bharani SN,Arbeit JM,Hyde JS,Dainauskas JR,Wilson RR

更新日期：1976-12-01 00:00:00

abstract：AIM OF STUDY:To evaluate patient profiles, diagnostic approaches, and treatment strategies in patients with lymph node tuberculosis. METHODS:Demographic data, diagnostic findings, and therapies were retrospectively analyzed in 60 patients with lymph node tuberculosis who were hospitalized between 1992 and 1999. RESUL...

journal_title：Chest

authors： Geldmacher H,Taube C,Kroeger C,Magnussen H,Kirsten DK

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The mid-portion of the maximal expiratory flow-volume (MEFV) curve is often described by values of the mean forced expired flow as lung volume decreases from 75% to 25% of vital capacity (ie, forced expiratory flow, midexpiratory phase [FEF(25-75)]). It is common practice to report also forced expired flow a...

journal_title：Chest

authors： Bar-Yishay E,Amirav I,Goldberg S

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Planning for mass critical care in resource-poor and constrained settings has been largely ignored, despite large, densely crowded populations who are prone to suffer disproportionately from natural disasters. As a result, disaster response has been suboptimal and in many instances hampered by lack of planni...

journal_title：Chest

authors： Geiling J,Burkle FM Jr,West TE,Uyeki TM,Amundson D,Dominguez-Cherit G,Gomersall CD,Lim ML,Luyckx V,Sarani B,Christian MD,Devereaux AV,Dichter JR,Kissoon N,Task Force for Mass Critical Care.,Task Force for Mass Critical Care

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Cheyne-Stokes respiration (CSR) frequently occurs in patients with severe heart failure during sleep and may increase mortality. Daytime CSR supposedly poses an even greater risk, but its prevalence and prognostic importance remain elusive. Therefore, we investigated the circadian prevalence of CSR and its i...

journal_title：Chest

authors： Brack T,Thüer I,Clarenbach CF,Senn O,Noll G,Russi EW,Bloch KE

更新日期：2007-11-01 00:00:00

abstract：:A diagnosis of severe obstructive sleep apnea was made after a 52-year-old hypertensive man developed a large intracranial hemorrhage. Therapeutic noninvasive positive pressure ventilation (NPPV) for obstructive sleep apnea and hypoventilation was complicated by transient unilateral orbital herniation. As best as can ...

journal_title：Chest

authors： Lazowick D,Meyer TJ,Pressman M,Peterson D

更新日期：1998-03-01 00:00:00

abstract：:Increased blood lactate concentration (hyperlactatemia) and lactic acidosis (hyperlactatemia and serum pH < 7.35) are common in patients with severe sepsis or septic shock and are associated with significant morbidity and mortality. In some patients, most of the lactate that is produced in shock states is due to inade...

journal_title：Chest

authors： Suetrong B,Walley KR

更新日期：2016-01-01 00:00:00

abstract：:Native valve endocarditis normally presents with fever and only later in its course demonstrates dysfunction of the affected valve. We describe a case of endocarditis due to Neisseria subflava, a Gram-negative diplococcal saprophyte of the oral cavity, which was unsuspected clinically and found unexpectedly during a m...

journal_title：Chest

authors： Amsel BJ,Moulijn AC

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Precapillary pulmonary hypertension (PH) is a complication of pulmonary Langerhans cell histiocytosis (PLCH) associated with increased mortality. However, outcomes and efficacy of pulmonary arterial hypertension (PAH) therapies in patients with PH complicating PLCH(PLCH-PH) remain unknown. METHODS:Consecuti...

journal_title：Chest

authors： Le Pavec J,Lorillon G,Jaïs X,Tcherakian C,Feuillet S,Dorfmüller P,Simonneau G,Humbert M,Tazi A

更新日期：2012-11-01 00:00:00

abstract：:Radiation therapy has been the usual initial treatment for mediastinal seminoma in the past. However, 25 to 40 percent of patients are not cured by this therapy, and other therapy is needed. Review of case reports show that vinblastine, bleomycin, and cis-platinum are effective therapy for metastatic disease, advanced...

journal_title：Chest

authors： Clamon GH

更新日期：1983-02-01 00:00:00

abstract：:Ischemic myocardium undergoes many physiologic changes, including alterations in contractile function, histologic condition, and oxygen utilization. Reperfusion of ischemic myocardium may reverse some of these changes; however, the level of reperfusion needed for adequate functional recovery, as opposed to myocyte sal...

journal_title：Chest

authors： Rohs TJ Jr,Benedict MB,Bolling SF

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and management of severe sepsis. We investigated the impact of one to two PCT determinations on ICU day 1 on health-care utilization and cost in a large research database. METHODS:A retrospective, propensity score-matched multivariabl...

journal_title：Chest

authors： Balk RA,Kadri SS,Cao Z,Robinson SB,Lipkin C,Bozzette SA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Severe pneumonia requiring ICU admission has not been well characterized with respect to long-term outcomes or predictors thereof. We examined the association between premorbid functional status and mortality in patients with severe pneumonia. METHODS:From 2000 to 2002, a population-based cohort of adults w...

journal_title：Chest

authors： Sligl WI,Eurich DT,Marrie TJ,Majumdar SR

更新日期：2011-01-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the role of craniofacial risk factors in increasing apneic activity between nonobese and obese habitual snorers. DESIGN:Cross-sectional. SETTING:Care-seeking volunteers identified through advertisements, and referral-based volunteers from two sleep centers serving the greater Cleveland ar...

journal_title：Chest

authors： Nelson S,Hans M

更新日期：1997-01-01 00:00:00

abstract：:A postmyocardial infarction left ventricular pseudoaneurysm occurs when a rupture of the ventricular free wall is contained by overlying, adherent pericardium. A postinfarction aneurysm, in contrast, is caused by scar formation resulting in thinning of the myocardium. Although the usual treatment for patients with pse...

journal_title：Chest

authors： Brown SL,Gropler RJ,Harris KM

更新日期：1997-05-01 00:00:00

abstract：:The solitary pulmonary nodule (SPN) is frequently encountered on chest imaging and poses an important diagnostic challenge to clinicians. The differential diagnosis is broad, ranging from benign granulomata and infectious processes to malignancy. Important concepts in the evaluation of SPNs include the definition, mor...

journal_title：Chest

authors： Patel VK,Naik SK,Naidich DP,Travis WD,Weingarten JA,Lazzaro R,Gutterman DD,Wentowski C,Grosu HB,Raoof S

更新日期：2013-03-01 00:00:00

abstract：:We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol. The initial episode was associated with hypertriglyceridemia, whereas the latter was not. The association between propofol and pancreatitis is...

journal_title：Chest

authors： Kumar AN,Schwartz DE,Lim KG

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVES:Primary pulmonary hypertension (PPH) is a pulmonary vasculopathy resulting in exercise intolerance, usually due to dyspnea. We hypothesized that ventilation is increased during exercise in PPH relative to normal because the ventilated lung is underperfused, cardiac output increase is restricted, and arterial...

journal_title：Chest

authors： Yasunobu Y,Oudiz RJ,Sun XG,Hansen JE,Wasserman K

更新日期：2005-05-01 00:00:00

abstract：:This report describes a patient with right lower lung (RLL) pneumonia of a subacute nature. Sputum and bronchial washings both grew N asteroides. Open lung biopsy showed bronchiolitis obliterans. Both the clinical and radiologic picture dramatically improved during three weeks of treatment with trimethoprim and sulfam...

journal_title：Chest

authors： Camp M,Mehta JB,Whitson M

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) results in high morbidity and health-care utilization. Diagnostic delays remain common and often occur in nonpulmonology settings. Screening for ILD in these settings has the potential to reduce diagnostic delays and improve patient outcomes. RESEARCH QUESTION:This study soug...

journal_title：Chest

authors： Pugashetti JV,Kitich A,Alqalyoobi S,Maynard-Paquette AC,Pritchard D,Graham J,Boctor N,Kulinich A,Lafond E,Foster E,Mendez C,Choudhry S,Chalaoui J,Morisset J,Kadoch M,Oldham JM

更新日期：2020-08-01 00:00:00

abstract：:We report a case of Pasteurella multocida pneumonia and its unusual clinical presentation. We also discuss the rarity of its diagnosis by TPC specimens and the delay in both an adequate diagnosis and treatment. ...

journal_title：Chest

authors： Ruiz-Santana S,Antunez IA,Armas M,Rodriguez de Castro F,Manzano JL

更新日期：1991-06-01 00:00:00

abstract：STUDY OBJECTIVES:Inspiratory capacity (IC) has been proposed as a simple method to assess acute changes in functional residual capacity (FRC) with bronchodilation, assuming that total lung capacity (TLC) is unchanged. This assumption is based on studies using body plethysmography, which may not accurately measure TLC i...

journal_title：Chest

authors： Duranti R,Filippelli M,Bianchi R,Romagnoli I,Pellegrino R,Brusasco V,Scano G

更新日期：2002-12-01 00:00:00

abstract：:Over the past 10 years, significant strides have been made in the understanding, development, and availability of sleep disorder therapeutics. In this review series, we discuss the current evidence surrounding the mechanisms of actions, indications, efficacy, and adverse side effects associated with the available arma...

journal_title：Chest

authors： Gulyani S,Salas RE,Gamaldo CE

更新日期：2012-12-01 00:00:00

abstract：:The upregulation of nitric oxide (NO) by inflammatory cytokines and mediators in central and peripheral airway sites can be monitored easily in exhaled air. It is now possible to estimate the predominant site of increased fraction of exhaled NO (FeNO) and its potential pathologic and physiologic role in various pulmon...

journal_title：Chest

authors： Barnes PJ,Dweik RA,Gelb AF,Gibson PG,George SC,Grasemann H,Pavord ID,Ratjen F,Silkoff PE,Taylor DR,Zamel N

更新日期：2010-09-01 00:00:00

abstract：:To evaluate comparative bronchodilator efficacy with chronic airflow obstruction (CAO), we randomly administered to ten patients week-long treatments consisting of: inhaled metaproterenol from a metered dose canister (1.30 mg six times a day) and doses of a sustained-release theophylline formulation sufficient to achi...

journal_title：Chest

authors： Dullinger D,Kronenberg R,Niewoehner DE

更新日期：1986-02-01 00:00:00

abstract：:We examined the degree of ventilatory constraint in patients with a history of chronic heart failure (CHF; n = 11; mean +/- SE age, 62 +/- 4 years; cardiac index [CI], 2.0 +/- 0.1; and ejection fraction [EF], 24 +/- 2%) and in control subjects (CTLS; n = 8; age, 61 +/- 5 years; CI, 2.6 +/- 0.3) by plotting the tidal f...

journal_title：Chest

authors： Johnson BD,Beck KC,Olson LJ,O'Malley KA,Allison TG,Squires RW,Gau GT

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...

journal_title：Chest

authors： Faust HE,Reilly JP,Anderson BJ,Ittner CAG,Forker CM,Zhang P,Weaver BA,Holena DN,Lanken PN,Christie JD,Meyer NJ,Mangalmurti NS,Shashaty MGS

更新日期：2020-01-01 00:00:00

abstract：:The authors believe this to be the first case report of atrial fibrillation following pulse methylprednisolone therapy in an adult. The literature regarding the complications of pulse methylprednisolone therapy is reviewed, with particular emphasis on the incidence and pathogenesis of arrhythmias. ...

journal_title：Chest

authors： McLuckie AE,Savage RW

更新日期：1993-08-01 00:00:00

abstract：:Cardiorespiratory values were measured in ten patients with severe respiratory failure on volume controlled and pressure controlled ventilation. Tidal volume, respirator rate, PEEP, auto-PEEP, inspiratory:expiratory ratio (1:2) and FIo2 were maintained at the same value for both ventilatory modalities. Changing from V...

journal_title：Chest

authors： Abraham E,Yoshihara G

更新日期：1990-12-01 00:00:00