Duck hepatitis B virus polymerase produced by in vitro transcription and translation possesses DNA polymerase and reverse transcriptase activities.

abstract：:A hydrogenase from a new species of sulfate reducing bacterium has been isolated and characterized. In contrast to other hydrogenases isolated from Desulfovibrio, this enzyme is found in the cytoplasmic fraction rather than in the periplasm. The specific activity of the enzyme, as measured in the hydrogen evolution as...

journal_title：Biochemical and biophysical research communications

authors： Czechowski MH,He SH,Nacro M,DerVartanian DV,Peck HD Jr,LeGall J

更新日期：1984-12-28 00:00:00

abstract：:Heme is central to oxygen sensing and utilization in all living organisms. It directly regulates numerous molecular and cellular processes for systems that sense or use oxygen. In mammals, heme plays an indispensable role in erythroid cell differentiation. To investigate heme regulatory functions, we identified, by di...

journal_title：Biochemical and biophysical research communications

authors： Zhu Y,Hon T,Zhang L

更新日期：1999-04-29 00:00:00

abstract：:Tumor necrosis factor receptor-associated factor 2 (TRAF2) has been demonstrated that it plays a significant role in cell death receptor signal transduction. The purpose of this study was to investigate the expression of TRAF2 and its possible role in FJOA. We observed an up-regulation of TRAF2 in FJOA by immunohistoc...

journal_title：Biochemical and biophysical research communications

authors： Jiang J,Zhang J,Wu C,Guo X,Chen C,Bao G,Sun Y,Chen J,Xue P,Xu G,Cui Z

更新日期：2018-09-10 00:00:00

abstract：:The cDNA encoding a swelling-induced chloride conductance regulatory protein, plcln, was cloned from rabbit ciliary epithelium by using a polymerase chain reaction (PCR)-based approach. The open reading frame encoding 236 amino acids possesses high amino acid identity (93/%) with the previously cloned plcln from human...

journal_title：Biochemical and biophysical research communications

authors： Wan XL,Chen S,Sears M

更新日期：1997-10-29 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is reported as a common and often fatal type of stroke accompanied with high morbidity and mortality, and it frequently results in long-lasting neurological dysfunctions. However, the pathogenesis that contributes to ICH has not been fully understood. Rnf112, also known as Znf179, is a m...

journal_title：Biochemical and biophysical research communications

authors： Zhang F,Zhang C

更新日期：2018-12-09 00:00:00

abstract：:The alpha-silyl amines benzyl-dimethyl-silyl-methanamine and the p-fluoro and p-chloro derivatives are potent time-dependent inhibitors of rat brain MAO-B. The inhibition exhibits saturation kinetics, takes place in the enzyme active-site and is irreversible. The most potent inhibitor in the series is 4-fluorobenzyl-d...

journal_title：Biochemical and biophysical research communications

authors： Danzin C,Collard JN,Marchal P,Schirlin D

更新日期：1989-04-28 00:00:00

abstract：:Tamoxifen, a widely used nonsteroidal antiestrogen in the treatment of breast cancer, forms several metabolites. 4-Hydroxytamoxifen (4-OHTam), a metabolite found in the bloodstream, has much higher affinity for the estrogen receptor than tamoxifen itself. Oxidative activation of 4-OHTam induces DNA damage. DNA isolate...

journal_title：Biochemical and biophysical research communications

authors： Sharma M

更新日期：2000-06-24 00:00:00

abstract：:The Notch protooncogene encodes a receptor important for determination and differentiation of many cell types, and is conserved between vertebrates and invertebrates. It has been suggested that the secreted protein scabrous (sca) might be a Notch ligand acting in the peripheral nervous system. The sca protein was puri...

journal_title：Biochemical and biophysical research communications

authors： Lee EC,Baker NE

更新日期：1996-08-23 00:00:00

abstract：:Porcine kidney betaine aldehyde dehydrogenase (EC 1.2.1.8) kinetic properties were determined at low substrate concentrations. The double-reciprocal plots of initial velocity versus substrate concentration are linear and intersect at the left of the 1/v axis and showed substrate inhibition with betaine aldehyde. Studi...

journal_title：Biochemical and biophysical research communications

authors： Figueroa-Soto CG,Valenzuela-Soto EM

更新日期：2000-03-16 00:00:00

abstract：:Mesenchymal stem cells (MSCs) isolated from several adult human tissues are reported to be a promising tool for regenerative medicine. In order to broaden the array of tools for therapeutic application, we isolated a new population of cells from adult human testis termed gonadal stem cells (GSCs). GSCs express CD105, ...

journal_title：Biochemical and biophysical research communications

authors： Gonzalez R,Griparic L,Vargas V,Burgee K,Santacruz P,Anderson R,Schiewe M,Silva F,Patel A

更新日期：2009-08-07 00:00:00

abstract：:Triple-negative breast cancer (TNBC) that lacks expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) is a breast cancer subtype with very aggressive metastasis and poor prognosis. Unique cartilage matrix-associated protein (UCMA) is a vitamin K-dependent...

journal_title：Biochemical and biophysical research communications

authors： Lee SH,Lee YJ,Park SI,Kim JE

更新日期：2020-10-01 00:00:00

abstract：:The prevalence of nonalcoholic fatty liver disease (NAFLD) is high and increasing throughout the world. The intense sterile inflammation stemming from steatosis plays a significant role in the development of NAFLD, but the mechanism is unclear. We found that the NLRC4 inflammasome was activated in an in vitro cell mod...

journal_title：Biochemical and biophysical research communications

authors： Chen Y,Ma K

更新日期：2019-04-09 00:00:00

abstract：:We cloned a cDNA encoding a novel extracellular signal-regulated kinase (ERK) 2-binding protein, EBITEIN1, by yeast two-hybrid screening. Northern and Western blotting experiments showed that the transcript and protein were expressed in the testes. Furthermore, immunohistochemical experiments showed that EBITEIN1 exis...

journal_title：Biochemical and biophysical research communications

authors： Miura K,Imaki J

更新日期：2008-04-04 00:00:00

abstract：:Streptavidin, which is one of the most widely used proteins in biotechnological application field and is active only in tetrameric form, was surface expressed on the surface of Bacillus subtilis spore. Spore coat protein of B. subtilis, CotG, was used as an anchoring motif to display streptavidin. FACS using anti-stre...

journal_title：Biochemical and biophysical research communications

authors： Kim JH,Lee CS,Kim BG

更新日期：2005-05-27 00:00:00

abstract：:Sarafotoxins (SRTXs) are endothelin-like peptides extracted from snake venom. SRTXs stimulate the endothelin ETA and ETB receptors and enhance vasoconstriction, followed by left ventricular dysfunction and bronchoconstriction. SRTXs include four major isopeptides, S6a-d, with different subtype selectivities. Here, we ...

journal_title：Biochemical and biophysical research communications

authors： Izume T,Miyauchi H,Shihoya W,Nureki O

更新日期：2020-07-23 00:00:00

abstract：:The calcium homeostasis of the endoplasmic reticulum (ER) is connected to a multitude of cell functions involved in intracellular signal transduction, control of proliferation, programmed cell death, or the synthesis of mature proteins. Calcium is accumulated in the ER by various biochemically distinct sarco/endoplasm...

journal_title：Biochemical and biophysical research communications

authors： Papp B,Brouland JP,Gélébart P,Kovàcs T,Chomienne C

更新日期：2004-10-01 00:00:00

abstract：:HTLV-I is implicated with adult T-cell leukemia and certain other clinical disorders. The viral Tax protein is regarded as a key element in HTLV-I pathogenicity due to its ability to activate a wide variety of cellular regulatory factors. As such, Tax may likely activate also latent infection of certain other pathogen...

journal_title：Biochemical and biophysical research communications

authors： Tabakin-Fix Y,Huleihel M,Aboud M

更新日期：2004-06-11 00:00:00

abstract：:To study polygenetically inherited human diseases like hypertension, inbred rat strains are usually the preferred models. Because many inbred generations under optimized environmental conditions may have led to the survival of "silent" disease genes, we used a cross between one wild rat and genetically hypertensive SH...

journal_title：Biochemical and biophysical research communications

authors： Klöting I,Kovács P,van den Brandt J

更新日期：2001-06-29 00:00:00

abstract：:Dimethylglycine dehydrogenase (DMGDH) is a mammalian mitochondrial enzyme which plays an important role in the utilization of methyl groups derived from choline. DMGDH is a flavin containing enzyme which catalyzes the oxidative demethylation of dimethylglycine in vitro with the formation of sarcosine (N-methylglycine)...

journal_title：Biochemical and biophysical research communications

authors： Luka Z,Pakhomova S,Loukachevitch LV,Newcomer ME,Wagner C

更新日期：2014-07-11 00:00:00

abstract：:Fiber X-ray diffraction and measurement of fibre dimensions yield information about the effects of a mechanical tension on hydration of DNA in fibres. At a given relative humidity, the mechanical tension changes the DNA conformation but does not modify the number of water molecules associated to a nucleotide. The numb...

journal_title：Biochemical and biophysical research communications

authors： Harmouchi M,Albiser G,Premilat S

更新日期：1992-10-15 00:00:00

abstract：:Reactive oxygen species (ROS) are a continuous hazard in eukaroytic cells by their ability to cause damage to biomolecules, in particular to DNA. Previous data indicated that the cytosolic serine peptidase tripeptidyl-peptidase II (TPPII) translocates into the nucleus of most tumor cell lines in response to gamma-irra...

journal_title：Biochemical and biophysical research communications

authors： Preta G,de Klark R,Chakraborti S,Glas R

更新日期：2010-08-27 00:00:00

abstract：:DR4, a tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor, is a key element in the extrinsic pathway of TRAIL/TRAIL receptor-related apoptosis that exerts a preferential toxic effect against tumor cells. However, TRAIL and DR4 are expressed in various normal cells, and recent studies indicate tha...

journal_title：Biochemical and biophysical research communications

authors： Kang MS,Lee SK,Park CS,Kang JH,Bae SH,Yu SL

更新日期：2008-11-14 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are shown to potentiate NGF-induced neuronal differentiation in PC12 phaeochromocytoma cells grown on collagen under low-serum conditions. Whereas, cell bodies remained rounded in control medium or with only BMPs present, addition of BMP4 or BMP6 robustly increased the neuritogenic e...

journal_title：Biochemical and biophysical research communications

authors： Althini S,Usoskin D,Kylberg A,ten Dijke P,Ebendal T

更新日期：2003-08-01 00:00:00

abstract：:The effect of sex steroids on the regulation of hepatocyte resting membrane potential (Em) was investigated. In adult rat liver snips, Em was significantly lower in males than females. In prepubertal animals no sex related difference was observed and the Em was comparable to that of adult females. Exposure of the huma...

journal_title：Biochemical and biophysical research communications

authors： Motzkin SM,Feinstein J,Tiribelli C

更新日期：1990-11-15 00:00:00

abstract：:Dynamic properties of spin-labelled heterosaccharides in the Fc-region of murine monoclonal antihapten immunoglobulin G were studied in model immune complexes (IC) as a function of the IC size. Model IC dimers, trimers and oligomers were formed using bivalent photoaffinity antigens. The ESR spectrum exhibits two compo...

journal_title：Biochemical and biophysical research communications

authors： Kusumi A,Winkelhake JL

更新日期：1986-05-29 00:00:00

abstract：:Transforming growth factor beta (TGFbeta) is a critical immunosuppressive cytokine that inhibits the cell-mediated immune responses partly via inhibition of immunostimulatory cytokine production from T cells, NK cells, and macrophages. Here we investigated the effect of TGFbeta on NK cell activation induced by interle...

journal_title：Biochemical and biophysical research communications

authors： Hayashi H,Inoue Y,Tsutsui H,Okamura H,Nakanishi K,Onozaki K

更新日期：2003-01-24 00:00:00

abstract：:Treatment of the cells of the 311 cell line, a pluripotent mouse teratocarcinoma cell line, with 12-O-tetradecanoylphorbol-13-acetate (TPA) modulates c-mos expression. Transient suppression of 6.1 and 4.6 kilobases (kb) transcripts and activation of 1.8 transcript indicate that TPA mediates concurrently positive and n...

journal_title：Biochemical and biophysical research communications

authors： Ogiso Y,Kitagawa K,Nishino H,Iwashima A

更新日期：1988-07-15 00:00:00

abstract：:The sIgG(+) lymphoblastoid B cell line CESS spontaneously produces a high amount of NGF and expresses both high affinity (p140(Trk-A)) and low affinity (p75(NTR)) NGF receptors. Blocking NGF signals with neutralizing antibodies or specific Trk-A inhibitors induces a rapid phosphorylation of antiapoptotic Bcl-2 protein...

journal_title：Biochemical and biophysical research communications

authors： Rosini P,De Chiara G,Lucibello M,Garaci E,Cozzolino F,Torcia M

更新日期：2000-11-30 00:00:00

abstract：:Endothelial cells line the inside of all blood vessels forming a structurally and functionally highly heterogenous population of cells. Here we describe the application of the differential RNA display technique to the analysis of the heterogeneity of endothelial cells. Multiple fragment cDNAs from quiescent resting an...

journal_title：Biochemical and biophysical research communications

authors： Kozian DH,Augustin HG

更新日期：1995-04-26 00:00:00

abstract：:Dexamethasone produced an increased activity of stearoyl-CoA desaturase through the enhancement of delta 9-terminal component activity, and a corresponding decrease of oleoyl-CoA desaturase activity via the reduced activity of delta 12-terminal component in Tetrahymena microsomes. However, the content of cytochrome b5...

journal_title：Biochemical and biophysical research communications

authors： Umeki S,Nozawa Y

更新日期：1984-02-29 00:00:00