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Effect of a mechanical tension on the hydration of DNA in fibres.

Abstract：

:Fiber X-ray diffraction and measurement of fibre dimensions yield information about the effects of a mechanical tension on hydration of DNA in fibres. At a given relative humidity, the mechanical tension changes the DNA conformation but does not modify the number of water molecules associated to a nucleotide. The number of water molecules per nucleotide necessary to maintain B form decreases for increasing tensions applied to the DNA fibre. Form transitions can be opposed by mechanical tensions; an energy of 1 Kcal per mole of nucleotide pairs is sufficient to prevent the B to A transition.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Harmouchi M,Albiser G,Premilat S

doi

10.1016/0006-291x(92)92352-x

subject

Has Abstract

pub_date

1992-10-15 00:00:00

pages

78-85

issue

1

eissn

0006-291X

issn

1090-2104

pii

0006-291X(92)92352-X

journal_volume

188

pub_type

杂志文章

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