Abstract：
:The antimicrobial activity against Clostridium difficile of 109 lactic acid bacteria (LAB) isolated from 32 healthy Korean infants was measured. The ability to show similar activity against Escherichia coli O157:H7 and Staphylococcus aureus was also looked for. Twelve of the 109 LAB showed activity against C. difficile and 19 strains were active against E. coli O157:H7, but none against S. aureus. Four strains had antimicrobial activity against both C. difficile and E. coli O157:H7. Of the 12 strains that had activity against C. difficile, four strains were excluded as Streptococcus species, while the other eight were identified using polymerase chain reaction (PCR) assays using group-specific primers designed from the nucleotide sequences of the 16S rDNA and internal transcribed spacer (ITS) regions of the Bifidobacterium and Lactobacillus species. Based on the sequencing results, the eight strains screened were identified as Bifidobacterium infantis and Lactobacillus salivarius.
journal_name
Int J Antimicrob Agentsjournal_title
International journal of antimicrobial agentsauthors
Lee YJ,Yu WK,Heo TRdoi
10.1016/s0924-8579(02)00389-8subject
Has Abstractpub_date
2003-04-01 00:00:00pages
340-6issue
4eissn
0924-8579issn
1872-7913pii
S0924857902003898journal_volume
21pub_type
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journal_title：International journal of antimicrobial agents
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journal_title：International journal of antimicrobial agents
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