Styrene-catabolism regulation in Pseudomonas fluorescens ST: phosphorylation of StyR induces dimerization and cooperative DNA-binding.

abstract：:Glycosaminoglycans were prepared from the Engelbreth-Holm-Swarm mouse tumor. Enzymatic analysis demonstrated heparan sulfate (95.8%) and chondroitinase ABC-sensitive galactosaminoglycans (4.2%). HPLC analysis of the disaccharide units showed that heparan sulfate chains were undersulfated on average, comprising approxi...

journal_title：Biochemical and biophysical research communications

authors： Sugahara K,Okumura Y,Yamashina I

更新日期：1989-07-14 00:00:00

abstract：:Pretreatment of brain synaptic membrane homogenates with Triton X-100 resulted in a drastic disclosure of [3H] glutamate (Glu) binding activity which was sensitive to one of the central Glu receptor agonists, N-methyl-D-aspartic acid (NMDA). The NMDA-sensitive binding was inversely dependent on the incubation temperat...

journal_title：Biochemical and biophysical research communications

authors： Ogita K,Yoneda Y

更新日期：1988-06-16 00:00:00

abstract：:Caveolae are cholesterol enriched invaginations of the plasma membrane involved in a variety of processes, including glucose and fatty acids absorption, cell transduction and mechanoprotection. The biogenesis and function of caveolae depend on the activity of Caveolin (Cav-1, -2 and -3) and Cavin (Cavin-1, -2, -3 and ...

journal_title：Biochemical and biophysical research communications

authors： Codenotti S,Vezzoli M,Poliani PL,Cominelli M,Monti E,Fanzani A

更新日期：2017-11-04 00:00:00

abstract：:Mitochondria isolated from rats chronically fed ethanol were more sensitive to induction of the mitochondrial permeability transition (MPT) by a variety of agents than mitochondria isolated from isocalorically matched controls. The agents utilized have been implicated in both necrotic (Ca(2+)) and apoptotic (ceramide,...

journal_title：Biochemical and biophysical research communications

authors： Pastorino JG,Marcineviciute A,Cahill A,Hoek JB

更新日期：1999-11-19 00:00:00

abstract：:Expression of foreign genes in vivo is a standard method to disclose functions of specific genes and to alter physiological conditions in distinct cell types and tissues. Virus-mediated gene transfer has proved to be a valuable tool for directed gene expression in vivo complementary to transgenic approaches. However, ...

journal_title：Biochemical and biophysical research communications

authors： Ebelt H,Braun T

更新日期：2003-10-31 00:00:00

abstract：:Sugarcane (Saccharum sp. hybrid) provides the main source of sugar for humans. Sugarcane mosaic disease (SMD) is a major threat to sugarcane production. Currently, control of SMD is mainly dependent on breeding resistant cultivars through hybridization, which is time-consuming. Understanding the mechanism of viral inf...

journal_title：Biochemical and biophysical research communications

authors： Zhai Y,Deng Y,Cheng G,Peng L,Zheng Y,Yang Y,Xu J

更新日期：2015-10-23 00:00:00

abstract：:Tooth and bone are major tissues involved in physiological calcification in the body, and they use similar molecular pathways for development, homeostasis, and regeneration. Harmine (HMN) is a natural small compound that stimulates osteoblast differentiation in vitro and in vivo. Here we examined the biological effect...

journal_title：Biochemical and biophysical research communications

authors： Fujiwara N,Lee JW,Kumakami-Sakano M,Otsu K,Woo JT,Iseki S,Ota MS

更新日期：2018-03-11 00:00:00

abstract：:Binding of cytochrome b5 to rat cytochrome P450 2B1 was inhibited (by 75%) by a synthetic peptide corresponding to P450 residues 116-134. The role of Lys-122 and Arg-125 were evaluated using peptides in which one or both of these basic residues were replaced with Glu. The Lys-122 substitution nearly abolished while th...

journal_title：Biochemical and biophysical research communications

authors： Omata Y,Sakamoto H,Robinson RC,Pincus MR,Friedman FK

更新日期：1994-06-30 00:00:00

abstract：:The amino acid sequence of the polyclonal antibodies we developed against the carboxyl terminus of the dystrophin-related protein, the putative gene product of B3 cDNA, had no homologous sequence to the dystrophin molecule except for two amino acids located at its ends for immunization. By immunohistochemical examinat...

journal_title：Biochemical and biophysical research communications

authors： Takemitsu M,Ishiura S,Koga R,Kamakura K,Arahata K,Nonaka I,Sugita H

更新日期：1991-11-14 00:00:00

abstract：:Etoposide-induced 2.4 kb transcript (EI24, also known as PIG8) is a p53 target gene involved in cell growth suppression and apoptosis and known to be frequently altered in human cancers. Although EI24 expression is decreased in various cancers and is associated with colorectal cancer progression and metastasis, the ph...

journal_title：Biochemical and biophysical research communications

authors： Nam TW,Park SY,Lee JH,Roh JI,Lee HW

更新日期：2019-07-05 00:00:00

abstract：:Postmenopausal women treated with estrogen hormone replacement therapy and female patients with hypoplasminogenemia receiving oral contraceptives show increasing plasminogen (PLG) concentrations. The elevated PLG levels are in contrast to the estrogen dependent decline of lipoptrotein(a) [Lp(a)], whose main protein co...

journal_title：Biochemical and biophysical research communications

authors： Kobelt L,Klammt J,Tefs K,Schuster V

更新日期：2013-08-16 00:00:00

abstract：:Hepatitis B virus X protein (HBx protein), which seems to be involved in hepatocarcinogenesis, was studied for its effect on cell growth regulation. We examined the response to growth inhibition of transforming growth factor beta 1 (TGF-beta 1) in HBx gene-introduced cells. HBx gene in pRc/CMV was transfected to mink ...

journal_title：Biochemical and biophysical research communications

authors： Oshikawa O,Tamura S,Kawata S,Ito N,Tsushima H,Kiso S,Matsuda Y,Yamada A,Tamai S,Matsuzawa Y

更新日期：1996-05-24 00:00:00

abstract：:Isoprenoids comprise a diverse group of natural products with a broad range of metabolic functions. Isoprenoids are synthesized from prenyl pyrophosphates by prenyltransferases that catalyze the isoprenoid chain-elongation process to different chain lengths. We hereby present the crystal structure of geranylgeranyl py...

journal_title：Biochemical and biophysical research communications

authors： Kim S,Kim EJ,Park JB,Kim SW,Kim KJ

更新日期：2019-10-20 00:00:00

abstract：:Skeletal tissue contains a network of nerve fibers expressing several neuropeptides, including vasoactive intestinal peptide (VIP) and the related peptide pituitary adenylate cyclase activating peptide (PACAP). These peptides have been demonstrated to regulate osteoclast formation and osteoclast activity. Using atomic...

journal_title：Biochemical and biophysical research communications

authors： Ransjö M,Lie A,Mukohyama H,Lundberg P,Lerner UH

更新日期：2000-08-02 00:00:00

abstract：:Previously we described the identification of a Plasmodium falciparum signal peptide peptidase (PfSPP) functioning at the blood stage of malaria infection. Our studies also demonstrated that mammalian SPP inhibitors prevent malaria parasite growth at the late-ring/early trophozoite stage of intra-erythrocytic developm...

journal_title：Biochemical and biophysical research communications

authors： Baldwin M,Russo C,Li X,Chishti AH

更新日期：2014-08-08 00:00:00

abstract：:Dysregulation of microRNAs has been demonstrated to be involved in a variety of biological events related to cancer, including proliferation, metastasis, angiogenesis and immune escape. MiR-616-3p is located on the chromosome region 12q13.3, however, its potential role and clinical implications in gastric cancer remai...

journal_title：Biochemical and biophysical research communications

authors： Wu ZH,Lin C,Liu CC,Jiang WW,Huang MZ,Liu X,Guo WJ

更新日期：2018-07-02 00:00:00

abstract：:The carnitine/acylcarnitine carrier from rat liver mitochondria was overexpressed in Escherichia coli. The expressed protein, recovered as inclusion bodies, was solubilized with sarkosyl and purified by Sephadex G-200 and celite chromatography. A yield of 15 mg of purified transport protein per liter of cell culture w...

journal_title：Biochemical and biophysical research communications

authors： Indiveri C,Iacobazzi V,Giangregorio N,Palmieri F

更新日期：1998-08-28 00:00:00

abstract：:Heme oxygenase-1 (HO-1) is an inducible form of heme oxygenase that catabolizes heme to carbon monoxide, biliverdin, and ferrous iron. We have investigated whether HO-1 can induce angiogenic effects in vivo. Rats were subjected to a bolus injection of either wild type adenovirus (ad-wt) or adenovirus encoding HO-1 (ad...

journal_title：Biochemical and biophysical research communications

authors： Suzuki M,Iso-o N,Takeshita S,Tsukamoto K,Mori I,Sato T,Ohno M,Nagai R,Ishizaka N

更新日期：2003-02-28 00:00:00

abstract：:Metabolic syndrome describes a group of clinical features that together increase the incidence of coronary artery disease, stroke and type 2 diabetes. Insulin resistance is a major risk factor for developing metabolic syndrome. A chronic state of inflammation accompanies the accumulation of surplus lipids in adipose a...

journal_title：Biochemical and biophysical research communications

authors： Ko SH,Lee JK,Lee HJ,Ye SK,Kim HS,Chung MH

更新日期：2014-01-10 00:00:00

abstract：:Efficient phagocytic clearance of apoptotic spermatogenic cells and residual bodies (RBs) by Sertoli cells (SCs) is crucial for functional mature spermatogenesis. However, little is known about the molecular mechanisms underlying this SCs function. Herein, we reported for the first time that SCs-expressing metastasis ...

journal_title：Biochemical and biophysical research communications

authors： Zhu CJ,Zhang S,Liang Y,Li W

更新日期：2014-03-14 00:00:00

abstract：:IL-17, which exerts strong pro-inflammatory effects, has emerged as an important mediator in inflammation-associated cancer. However, the characteristics of IL-17-producing cells, the relevance of IL-17 to clinical parameters and its function in the development and progression of colorectal carcinoma still remain to b...

journal_title：Biochemical and biophysical research communications

authors： Liu J,Duan Y,Cheng X,Chen X,Xie W,Long H,Lin Z,Zhu B

更新日期：2011-04-08 00:00:00

abstract：BACKGROUND:Chronic hypoxia plays an important role in the initiation and progression of chronic renal disease. The pathogenic role of chronic hypoxia in tubulointerstitial injury has been investigated widely, but little is known about acute hypoxia implications in glomerular damage. In this study, we investigated the e...

journal_title：Biochemical and biophysical research communications

authors： Hu G,He Y,Li Y,Hu X,Liu S,Liao C,Zhang R,Zhou X,Sun H

更新日期：2021-01-12 00:00:00

abstract：:We have identified by protein sequencing the precursor of beta protein in newborn rat brain. A rabbit antibody was raised against a synthetic peptide corresponding to the carboxyl-terminal 30 residues (666-695) of the putative beta-amyloid protein precursor (Kang et al. 1987). The antiserum recognized multiple bands a...

journal_title：Biochemical and biophysical research communications

authors： Takio K,Hasegawa M,Titani K,Ihara Y

更新日期：1989-05-15 00:00:00

abstract：:Leprechaunism is an inherited disorder characterized by growth restriction and severe insulin resistance and caused by mutations in the insulin receptor gene. Cells from these patients have defective insulin binding. Fibroblasts from some patients have concomitant defects in other tyrosine kinase receptors, such as th...

journal_title：Biochemical and biophysical research communications

authors： Longo N

更新日期：1993-12-15 00:00:00

abstract：:Cyclic adenosine diphosphoribose (cADPR) is a putative second messenger of calcium homeostasis synthesized from NAD by cleavage of the nicotinamide-ribose bond and cyclization of the ribose to the adenine ring. In this study, the ultraviolet absorption spectra of cADPR have been studied as a function of pH and compare...

journal_title：Biochemical and biophysical research communications

authors： Kim H,Jacobson EL,Jacobson MK

更新日期：1993-08-16 00:00:00

abstract：:Normal adult Sprague-Dawley rats were made anemic by repeated phlebotomy. Ion-exchange chromatography of anemic blood showed newborn like hemoglobin proportions, involving the same six hemoglobin components as is found when newborn and adult blood are compared. However, acetylsalicylic acid intake during anemia failed...

journal_title：Biochemical and biophysical research communications

authors： Datta MC,Josephs J,Tolbert ME,Anderson J,Dowla H

更新日期：1986-05-29 00:00:00

abstract：:Dengue Virus (DENV) infection is an important mosquito-borne viral disease and its clinical symptoms range from a predominantly febrile disease, dengue fever (DF), to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Increased levels of cytokines - the so-called 'cytokine storm', contribute to the pathog...

journal_title：Biochemical and biophysical research communications

authors： Suttitheptumrong A,Khunchai S,Panaampon J,Yasamut U,Morchang A,Puttikhunt C,Noisakran S,Haegeman G,Yenchitsomanus PT,Limjindaporn T

更新日期：2013-06-28 00:00:00

abstract：:A high-pressure stopped-flow apparatus developed in our laboratories provides the capability to use dissolved gaseous reactants at elevated concentrations in solution (in equilibrium with gas pressures up to ca. 30 atm) for measurement of reaction kinetics. We have used this apparatus to follow the reaction of dioxyge...

journal_title：Biochemical and biophysical research communications

authors： Bailey JA,James CA,Woodruff WH

更新日期：1996-03-27 00:00:00

abstract：:Pulmonary fibrosis is a progressive disorder whose molecular pathology is poorly understood. Here we developed an in-house cDNA microarray ("lung chip") originating from a lung-normalized cDNA library. By using this lung chip, we analyzed global gene expression in a murine model of bleomycin-induced fibrosis and selec...

journal_title：Biochemical and biophysical research communications

authors： Katsuma S,Nishi K,Tanigawara K,Ikawa H,Shiojima S,Takagaki K,Kaminishi Y,Suzuki Y,Hirasawa A,Ohgi T,Yano J,Murakami Y,Tsujimoto G

更新日期：2001-11-09 00:00:00

abstract：:Hyperglycemia-induced podocyte injury plays a vital role in the development of diabetic nephropathy. Sulfiredoxin-1 (Srxn1) is emerging as a cytoprotective protein that protects from various insults in a wide range of cell types. However, whether Srxn1 is involved in regulating hyperglycemia-induced podocyte injury an...

journal_title：Biochemical and biophysical research communications

authors： Shen Y,Chen S,Zhao Y

更新日期：2019-09-03 00:00:00