Abstract:
:The present review introduces the concept of 'non-permanent membrane proteins', to encompass the wide variety of proteins that are not found in a stable membrane-bound form under physiological conditions, yet they interact with the membrane at some stage of their specific course of action. Non-permanent membrane proteins can be codified by the cell's own genome, or else they may arise from a foreign genome. Non-permanent membrane proteins can be classified, according to the reversibility of the membrane interaction, into those with reversible and irreversible (very long-lived) membrane contacts. According to the nature (strength) of the interaction, non-permanent membrane proteins may be divided into those that interact weakly with the membrane, in an extrinsic-like form, and those that interact strongly with the membrane. The latter can in turn be classified into those that cause and those that do not cause covalent modification of the lipids, the latter behaving, after interacting with the membrane, in the way of the conventional intrinsic proteins. Multiple examples are provided for the different groups of non-permanent membrane proteins, and a more detailed description is given of three of them, representative of different groups, namely TrwD from plasmid R388, E. coli alpha-haemolysin and B. cereus sphingomyelinase.
journal_name
Mol Membr Bioljournal_title
Molecular membrane biologyauthors
Goñi FMdoi
10.1080/0968768021000035078subject
Has Abstractpub_date
2002-10-01 00:00:00pages
237-45issue
4eissn
0968-7688issn
1464-5203pii
KH5DWA8PT5Q20XCPjournal_volume
19pub_type
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journal_title:Molecular membrane biology
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abstract::Spontaneous membrane adsorption, folding and insertion of the synthetic WALP16 and KALP16 peptides was studied by computer simulations starting from completely extended conformations. The peptides were simulated using an unmodified all-atom force field in combination with an efficient Monte Carlo sampling algorithm. T...
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pub_type: 杂志文章
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更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/09687860600803223
更新日期:2006-09-01 00:00:00
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更新日期:2009-05-01 00:00:00
abstract::CitS of Klebsiella pneumoniae and GltS of Escherichia coli are Na+-dependent secondary transporters from different families that are believed to share the same fold and quaternary structure. A 10 kDa protein tag (Biotin Acceptor Domain [BAD]) was fused to the N-terminus of both proteins (CitS-BAD1 and GltS-BAD1, respe...
journal_title:Molecular membrane biology
pub_type: 杂志文章
doi:10.3109/09687688.2011.581252
更新日期:2011-08-01 00:00:00
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journal_title:Molecular membrane biology
pub_type: 杂志文章,评审
doi:10.1080/09687680110112929
更新日期:2002-01-01 00:00:00
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journal_title:Molecular membrane biology
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doi:
更新日期:2001-01-01 00:00:00
abstract::The transporter SbtA is a high affinity Na+-dependent HCO3- uptake system present in a majority of cyanobacterial clades. It functions in conjunction with CO2 uptake systems and other HCO3- uptake systems to allow cyanobacteria to accumulate high levels of HCO3- used to support efficient photosynthetic CO2 fixation vi...
journal_title:Molecular membrane biology
pub_type: 杂志文章
doi:10.3109/09687688.2011.593049
更新日期:2011-08-01 00:00:00
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journal_title:Molecular membrane biology
pub_type: 杂志文章
doi:10.3109/09687689509038493
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journal_title:Molecular membrane biology
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journal_title:Molecular membrane biology
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journal_title:Molecular membrane biology
pub_type: 杂志文章,评审
doi:10.3109/09687689509038489
更新日期:1995-01-01 00:00:00
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journal_title:Molecular membrane biology
pub_type: 杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:Molecular membrane biology
pub_type: 杂志文章,评审
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更新日期:2004-07-01 00:00:00
abstract::Glucosyltransferases (Gtrs) and O-acetyltransferase (Oac) are integral membrane proteins embedded within the cytoplasmic membrane of Shigella flexneri. Gtrs and Oac are responsible for unidirectional host serotype conversion by altering the epitopic properties of the bacterial surface lipopolysaccharide (LPS) O-antige...
journal_title:Molecular membrane biology
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abstract::Trypsin activation of Cry4B, a 130-kDa Bacillus thuringiensis (Bt) protein, produces a 65-kDa toxin active against mosquito larvae. The active toxin is made of two protease resistant-products of ca. 45 kDa and ca. 20 kDa. The cloned 21-kDa fragment consisting of the N-terminal region of the toxin was previously shown ...
journal_title:Molecular membrane biology
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journal_title:Molecular membrane biology
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更新日期:2005-01-01 00:00:00