Platelet-sparing effect of paclitaxel in heavily pretreated ovarian cancer patients.

abstract：BACKGROUND:Differences in individual body sizes have not been well considered when analyzing the survival of patients with non-small cell lung cancer (NSCLC). We hypothesized that physique-adjusted tumor size is superior to actual tumor size in predicting the prognosis. METHODS:Eight hundred and forty-two patients who...

journal_title：International journal of clinical oncology

authors： Ozeki N,Fukui T,Kawaguchi K,Nakamura S,Hakiri S,Kato T,Hirakawa A,Yokoi K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Although regorafenib or trifluridine/tipiracil (FTD/TPI) has been recognized as a later-line standard treatment in patients with metastatic colorectal cancer (mCRC), not all patients have beneficial outcomes. This study aimed to develop a prognostic scoring system for evaluating the overall survival (OS) ben...

journal_title：International journal of clinical oncology

authors： Moriwaki T,Fukuoka S,Masuishi T,Takashima A,Kumekawa Y,Kajiwara T,Yamazaki K,Esaki T,Makiyama A,Denda T,Hatachi Y,Suto T,Sugimoto N,Enomoto M,Ishikawa T,Kashiwada T,Oki E,Komatsu Y,Tsuji A,Tsuchihashi K,Sakai D,

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Because there are few exchanges of doctors and surgical techniques among leading Japanese hospitals, neck dissections in Japan have become so highly diverse that the uniformity and comparability of nonradical neck dissections have become questionable. METHODS:The Japan Neck Dissection Study Group (JNDSG) wa...

journal_title：International journal of clinical oncology

authors： Saikawa M,Kishimoto S

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The correlation between treatment-related factors and lung toxicity has not been sufficiently evaluated in salvage radiotherapy. METHODS:Twenty-one patients with recurrent non-small-cell lung cancer (NSCLC) after lobectomy received salvage radiotherapy to a total dose of 46-60 Gy. The effects of radiotherap...

journal_title：International journal of clinical oncology

authors： Uno T,Isobe K,Kawakami H,Ueno N,Kawata T,Yamamoto S,Sekine Y,Iyoda A,Iizasa T,Fujisawa T,Shigematsu N,Ito H

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Our aim was to study the efficacy and safety of combination chemotherapy with gemcitabine plus cisplatin (GC) for patients with advanced urothelial carcinoma (UC) after failure of methotrexate, vinblastin, adriamycin, and cisplatin (M-VAC) chemotherapy. METHODS:We studied a total of 33 patients with advance...

journal_title：International journal of clinical oncology

authors： Gondo T,Ohori M,Hamada R,Tanaka A,Satake N,Takeuchi H,Nakashima J,Hatano T,Tachibana M

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The Randomized Phase III Study Comparing Oxaliplatin plus S-1 with Cisplatin plus S-1 in Chemotherapy-naïve Patients with Advanced Gastric Cancer (G-SOX) showed the noninferiority of S-1 (an oral fluoropyrimidine-derivative dihydropyrimidine dehydrogenase inhibitor) plus oxaliplatin combination therapy (SOX)...

journal_title：International journal of clinical oncology

authors： Hamada C,Yamada Y,Azuma M,Nishikawa K,Gotoh M,Bando H,Sugimoto N,Nishina T,Amagai K,Chin K,Niwa Y,Tsuji A,Imamura H,Tsuda M,Yasui H,Fujii H,Yamaguchi K,Yasui H,Hironaka S,Shimada K,Miwa H,Hyodo I

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) were correlated with favorable clinical outcome in patients with melanoma. However, in metastatic renal cell carcinoma (mRCC) patients, there have been few reports about the correlation between ...

journal_title：International journal of clinical oncology

authors： Kato T,Nagahara A,Kawamura N,Nakata W,Soda T,Matsuzaki K,Hatano K,Kawashima A,Ujike T,Imamura R,Nishimura K,Takada S,Tsujihata M,Yamaguchi S,Takao T,Nishimura K,Nonomura N,Uemura M

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Soft-tissue tumors are often accompanied by abnormal temperature distribution detected during palpation. However, the assessment of temperature distribution is subjective, limiting its wide use in cancer screening. The aim of this study was to evaluate the clinical significance of the thermal detection of so...

journal_title：International journal of clinical oncology

authors： Shimatani A,Hoshi M,Oebisu N,Iwai T,Takada N,Nakamura H

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The risk factors of incisional surgical site infection (iSSI) after open radical cystectomy (ORC) have not been fully investigated. The aim of the present study is to examine factors correlated with iSSI development after ORC with intestinal urinary diversion. METHODS:A total of 178 patients who had undergo...

journal_title：International journal of clinical oncology

authors： Gondo T,Ohno Y,Nakashima J,Hashimoto T,Takizawa I,Tanaka A,Shimodaira K,Satake N,Takeuchi H,Nakagami Y,Ohori M,Tachibana M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Based on the results of the SPIRITS trial, combination chemotherapy of S-1 plus cisplatin (SP) is now considered the standard treatment for patients with advanced gastric cancer (AGC) in Japan. On the other hand, several non-Japanese studies have shown the efficacy of capecitabine plus cisplatin (XP), which ...

journal_title：International journal of clinical oncology

authors： Shitara K,Sawaki A,Matsuo K,Kondo C,Takahari D,Ura T,Tajika M,Niwa Y,Muro K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Panitumumab is a fully human, monoclonal antibody against the epidermal growth factor receptor. Previous studies in non-Japanese patients with solid tumors showed that panitumumab exhibited nonlinear pharmacokinetics, was well tolerated (skin toxicities were the most common treatment-related adverse events),...

journal_title：International journal of clinical oncology

authors： Doi T,Ohtsu A,Tahara M,Tamura T,Shirao K,Yamada Y,Otani S,Yang BB,Ohkura M,Ohtsu T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Pulmonary wedge resection is an option for lung cancer patients with limited cardiopulmonary preservation. As the impact of underlying lung status on the prognosis of such patients remains unclear, we assessed this issue. METHODS:A total of 149 borderline surgical candidates with localized lung cancer who h...

journal_title：International journal of clinical oncology

authors： Kawaguchi T,Sawabata N,Miura S,Kawai N,Yasukawa M,Tojo T,Taniguchi S

更新日期：2019-04-01 00:00:00

abstract：:Standard definitive radiotherapy for cervical cancer consists of whole pelvic external beam radiotherapy (EBRT) and intracavitary brachytherapy (ICBT). In Japan, high-dose-rate ICBT (HDR-ICBT) has been utilized in clinical practice for more than 40 years. Several randomized clinical trials demonstrated that HDR-ICBT a...

journal_title：International journal of clinical oncology

authors： Toita T

更新日期：2009-02-01 00:00:00

abstract：BACKGROUNDS:The presence of ≥5 circulating tumor cells (CTCs) in 7.5 ml blood is a poor prognostic marker in metastatic breast cancer (MBC). However, the role of human epidermal growth factor receptor 2 (HER2) status in CTCs is not known. METHODS:We prospectively assessed the prognostic value of this parameter for pat...

journal_title：International journal of clinical oncology

authors： Hayashi N,Nakamura S,Tokuda Y,Shimoda Y,Yagata H,Yoshida A,Ota H,Hortobagyi GN,Cristofanilli M,Ueno NT

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:We have performed 26 vaginal radical trachelectomies (RTs) for patients with early invasive uterine cervical cancer since 2003 and, to date, have experienced 8 deliveries. The procedure has a high risk for preterm labor and the subsequent occurrence of preterm premature rupture of membranes (pPROM). We repor...

journal_title：International journal of clinical oncology

authors： Takada S,Ishioka S,Endo T,Baba T,Morishita M,Akashi Y,Mizuuchi M,Adachi H,Kim M,Saito T

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Zoledronic acid treatment reduces the incidence of skeletal-related events (SREs) in patients with bone metastases from breast, lung, and urologic cancers including prostate and renal cancer. The aim of this study was to evaluate the effect of zoledronic acid on SREs in patients with bone metastases from bla...

journal_title：International journal of clinical oncology

authors： Zaghloul MS,Boutrus R,El-Hossieny H,Kader YA,El-Attar I,Nazmy M

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Opioids are key drugs for cancer pain relief, but some patients, especially those who have gastroenterological cancers, suffer from severe opioid-induced bowel dysfunction (OBD), which reduces their quality of life. In order to achieve better pain relief, efforts to minimize OBD are required. METHODS:Betwee...

journal_title：International journal of clinical oncology

authors： Matsui T,Kojima T,Kojima H,Iwamoto N,Kure S,Uemura T,Fujimitsu Y,Sakamoto J

更新日期：2009-06-01 00:00:00

abstract：:A 74-year-old female was referred to our hospital for non-muscle invasive bladder tumors initially treated at another hospital. Preoperatively, computed tomography and magnetic resonance imaging demonstrated non-muscle invasive bladder tumors and a vaginal tumor. A second transurethral resection of the bladder tumors,...

journal_title：International journal of clinical oncology

authors： Kaneko G,Kikuchi E,Hasegawa M,Miyajima A,Nakagawa K,Kameyama K,Oya M

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:In treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN), the use of docetaxel, cisplatin, and 5-fluorouracil (TPF) followed by high-dose cisplatin chemoradiotherapy (CRT) carries concerns over toxicity. We evaluated the feasibility of TPF as induction chemotherapy (IC) to Japane...

journal_title：International journal of clinical oncology

authors： Okano S,Enokida T,Onoe T,Ota Y,Motegi A,Zenda S,Akimoto T,Tahara M

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarker...

journal_title：International journal of clinical oncology

authors： Ruggiero A,De Rosa G,Rizzo D,Leo A,Maurizi P,De Nisco A,Vendittelli F,Zuppi C,Mordente A,Riccardi R

更新日期：2013-10-01 00:00:00

abstract：:We report a patient with avascular necrosis of the bilateral femoral head resulting from long-term steroid administration for radiation pneumonitis that occurred after tangential irradiation of the breast. The patient was a 50-year-old postmenopausal woman with breast cancer, stage IIIB (T4bN0M0) in the right C area. ...

journal_title：International journal of clinical oncology

authors： Kosaka Y,Mitsumori M,Araki N,Yamauchi C,Nagata Y,Hiraoka M,Kodama H

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to determine if quantitative SUV-related, volumetric FDG PET parameters, and texture features (SPs, VPs, and TFs, respectively) were useful to evaluate and predict response and recurrence after chemotherapy in follicular lymphoma (FL). METHODS:Pre- and posttreatment FDG PET examin...

journal_title：International journal of clinical oncology

authors： Tatsumi M,Isohashi K,Matsunaga K,Watabe T,Kato H,Kanakura Y,Hatazawa J

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate microvessel density (MVD) as assessed by C-type lectin 14A (CLEC14A), which is a new marker for endothelial cells, and compare its expression to CD31 and CD105 in epithelial ovarian cancer (EOC). METHODS:MVD was evaluated in tumors (n = 50) from patients with EOC who...

journal_title：International journal of clinical oncology

authors： Krishna Priya S,Kumar K,Hiran KR,Bindhu MR,Nagare RP,Vijaykumar DK,Ganesan TS

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Lip carcinomas are rare oral tumors, and there have been few reports of lip carcinoma in Japan. METHODS:Of 914 patients with oral carcinomas treated between January 1980 and December 1998, 12 (1.3%) had lip carcinoma and 5 (0.5%) had lip mucosal carcinoma. We investigated the clinicopathological features of...

journal_title：International journal of clinical oncology

authors： Ogura I,Amagasa T,Iwaki H,Kijima T,Kurabayashi T,Yoshimasu H

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The efficacy of direct oral anti-coagulants (DOACs) for the treatment of venous thromboembolism (VTE) in Japanese patients with advanced cancer is largely unknown. METHODS:This prospective single-center observational study enrolled Japanese patients with unresectable advanced cancer who started DOAC treatme...

journal_title：International journal of clinical oncology

authors： Oyakawa T,Muraoka N,Iida K,Kusuhara M,Mori K

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) patients are usually diagnosed in advanced stages which results in high mortality. This study aimed to identify novel circulating miRNAs as biomarkers for the early detection of GC. METHODS:Candidate miRNA was identified after integrated analysis of two Gene Expression Omnibus (GEO) data...

journal_title：International journal of clinical oncology

authors： Shi Y,Wang Z,Zhu X,Chen L,Ma Y,Wang J,Yang X,Liu Z

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Microvascular invasion (mvi) is an important risk factor for recurrent hepatocellular carcinoma (HCC), even after curative liver resection or orthotopic liver transplantation. However, mvi is difficult to detect preoperatively. The aim of this study was to clarify the risk factors of postoperative recurrence...

journal_title：International journal of clinical oncology

authors： Imura S,Teraoku H,Yoshikawa M,Ishikawa D,Yamada S,Saito Y,Iwahashi S,Ikemoto T,Morine Y,Shimada M

更新日期：2018-02-01 00:00:00

abstract：:5-Fluorouracil (5-FU) has been the most widely accepted and studied chemotherapeutic agent, and many combination chemotherapeutic regimens have been reported. However, until recently, a standard regimen for metastatic gastric cancer had not been established. The combination of S-1 and cisplatin is a good candidate as ...

journal_title：International journal of clinical oncology

authors： Yoshida K,Yamaguchi K,Osada S,Kawaguchi Y,Takahashi T,Sakashita F,Tanaka Y

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:This study aimed to explore the potential risk factors of platinum allergy and follow-up treatment to provide a reference for the clinical prevention and treatment of platinum allergic reactions in patients with gynecological tumors. METHODS:The study retrospectively analyzed 45 cases of platinum allergic r...

journal_title：International journal of clinical oncology

authors： Ma X,Li X

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Despite increasing interest in minimally invasive surgery, prevalence data are completely absent. Our objective was to analyze clinico-epidemiological variations of surgery for renal malignancy in Japan with emphasis on annual trends and regional gaps, and to analyze factors affecting choice of open versus m...

journal_title：International journal of clinical oncology

authors： Sugihara T,Yasunaga H,Horiguchi H,Tsuru N,Fujimura T,Nishimatsu H,Kume H,Ohe K,Matsuda S,Fushimi K,Homma Y

更新日期：2013-12-01 00:00:00