Prognostic impact of underlying lung disease in pulmonary wedge resection for lung cancer.

Abstract:

BACKGROUND:Pulmonary wedge resection is an option for lung cancer patients with limited cardiopulmonary preservation. As the impact of underlying lung status on the prognosis of such patients remains unclear, we assessed this issue. METHODS:A total of 149 borderline surgical candidates with localized lung cancer who had undergone wedge resection were retrospectively investigated. Clinical variables related to perioperative morbidity, local control rate, and oncological outcomes based on underlying lung disease were analyzed. RESULTS:According to the risk analysis of postoperative complications, underlying lung disease did not influence the surgical morbidity. Postoperative recurrence occurred in 65 patients (locoregional recurrence in 36, distant metastasis in 12, and both simultaneously in 17). Multivariate analysis revealed that emphysema on computed tomography (CT) [hazard ratio (HR) 0.45; 95% confidence interval (CI) 0.21-0.99] was an independent indicator of locoregional recurrence. Forty-four patients died of lung cancer and 29 of other causes. Multivariate analysis demonstrated that interstitial lung disease on CT (HR 1.98; 95% CI 1.01-3.89) was a predictor of poor prognosis. CONCLUSION:Pulmonary wedge resection can be safely undergone by lung cancer patients regardless of pulmonary comorbidity, although underlying lung disease may influence the prognosis after wedge resection.

journal_name

Int J Clin Oncol

authors

Kawaguchi T,Sawabata N,Miura S,Kawai N,Yasukawa M,Tojo T,Taniguchi S

doi

10.1007/s10147-018-1367-3

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

366-374

issue

4

eissn

1341-9625

issn

1437-7772

pii

10.1007/s10147-018-1367-3

journal_volume

24

pub_type

杂志文章
  • Treatment strategies for neuroendocrine carcinoma of the upper digestive tract.

    abstract:BACKGROUND:Neuroendocrine carcinoma (NEC) of the esophagus and the stomach is aggressive. The purpose of this study was to determine the optimal therapeutic strategy. METHODS:Both clinicopathological factors and treatment results were examined in 34 patients with immunohistochemically diagnosed NEC of the upper gastro...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-020-01631-y

    authors: Morita M,Taguchi K,Kagawa M,Nakanoko T,Uehara H,Sugiyama M,Ota M,Ikebe M,Sugimachi K,Esaki T,Toh Y

    更新日期:2020-05-01 00:00:00

  • Prognostic significance of syndecan-1 expression in squamous cell carcinoma of the tonsil.

    abstract:BACKGROUND:Syndecan-1 (SDC1) is reported to modulate several key processes of tumorigenesis and to show variable expression in many cancers. The cause of these variations in expression is not known to date. In this study, we compared SDC1 status with clinicopathologic parameters to evaluate the prognostic implications ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0552-7

    authors: Lee SH,Choi EJ,Kim MS,Park JW,Lee YS,Kim SY,Kang CS

    更新日期:2014-04-01 00:00:00

  • Factors predicting incisional surgical site infection in patients undergoing open radical cystectomy for bladder cancer.

    abstract:BACKGROUND:The risk factors of incisional surgical site infection (iSSI) after open radical cystectomy (ORC) have not been fully investigated. The aim of the present study is to examine factors correlated with iSSI development after ORC with intestinal urinary diversion. METHODS:A total of 178 patients who had undergo...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0646-2

    authors: Gondo T,Ohno Y,Nakashima J,Hashimoto T,Takizawa I,Tanaka A,Shimodaira K,Satake N,Takeuchi H,Nakagami Y,Ohori M,Tachibana M

    更新日期:2014-10-01 00:00:00

  • Sentinel lymph node biopsy after neoadjuvant chemotherapy predicts pathological axillary lymph node status in breast cancer patients with clinically positive axillary lymph nodes at presentation.

    abstract:BACKGROUND:It is still controversial whether axillary lymph node (ALN) dissection (ALND) can be omitted after negative sentinel lymph node (SLN) biopsy (SLNB) in breast cancer (BC) patients with clinically positive ALNs at presentation treated with neoadjuvant chemotherapy (NAC). The study aim was to analyze whether SL...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-012-0418-4

    authors: Takei H,Yoshida T,Kurosumi M,Inoue K,Matsumoto H,Hayashi Y,Higuchi T,Uchida S,Ninomiya J,Kubo K,Oba H,Nagai S,Tabei T

    更新日期:2013-06-01 00:00:00

  • Preplanned safety analysis of the JFMC37-0801 trial: a randomized phase III study of six months versus twelve months of capecitabine as adjuvant chemotherapy for stage III colon cancer.

    abstract:BACKGROUND:Six months of adjuvant chemotherapy is regarded as the standard of care for patients with stage III colon cancer. However, whether longer treatment can improve prognosis has not been fully investigated. We conducted a phase III study comparing 6 and 12 months of adjuvant capecitabine chemotherapy for stage I...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10147-016-1083-9

    authors: Suto T,Ishiguro M,Hamada C,Kunieda K,Masuko H,Kondo K,Ishida H,Nishimura G,Sasaki K,Morita T,Hazama S,Maeda K,Mishima H,Ike H,Sadahiro S,Sugihara K,Okajima M,Saji S,Sakamoto J,Tomita N

    更新日期:2017-06-01 00:00:00

  • Metastatic collecting duct carcinoma of the kidney responded to sunitinib.

    abstract::Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive malignant tumor arising from the distal collecting tubules which has been shown to have a poor response to several kinds of systemic therapy. We present a case of metastatic CDC that responded favorably to a multiple tyrosine kinase inhibitor, suni...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-010-0116-z

    authors: Miyake H,Haraguchi T,Takenaka A,Fujisawa M

    更新日期:2011-04-01 00:00:00

  • Can hybrid FDG-PET/CT detect subclinical lymph node metastasis of esophageal cancer appropriately and contribute to radiation treatment planning? A comparison of image-based and pathological findings.

    abstract:BACKGROUND:We aimed to determine the appropriateness of adding 18F-fluorodeoxyglucose (FDG)-positronemission tomography (PET) to computed tomography (CT) and other pre-existing diagnostic imaging modalities for detecting subclinical lymph node metastasis of esophageal cancer, by comparing images from these modalities w...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-009-0893-4

    authors: Shimizu S,Hosokawa M,Itoh K,Fujita M,Takahashi H,Shirato H

    更新日期:2009-10-01 00:00:00

  • Phase I studies of nogitecan hydrochloride for Japanese.

    abstract:BACKGROUND:SmithKline Beecham synthesized camptothecin analogs and identified nogitecan hydrochloride (topotecan) with a broad spectrum of antitumor activity and less toxicity than camptothecin. Because preclinical and overseas clinical data indicated the antitumor effect of nogitecan hydrochloride with a 5-day repeat-...

    journal_title:International journal of clinical oncology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/s101470200026

    authors: Kobayashi K,Hino M,Fukuoka M,Takeuchi K,Furuse K,Yoneda S,Hasegawa K,Noda K,Kinoshita H,Kimura I,Taguchi T,Kanamaru R,Horikoshi N,Niitani H

    更新日期:2002-06-01 00:00:00

  • Challenge for a better combination with basic evidence.

    abstract::5-Fluorouracil (5-FU) has been the most widely accepted and studied chemotherapeutic agent, and many combination chemotherapeutic regimens have been reported. However, until recently, a standard regimen for metastatic gastric cancer had not been established. The combination of S-1 and cisplatin is a good candidate as ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10147-008-0793-z

    authors: Yoshida K,Yamaguchi K,Osada S,Kawaguchi Y,Takahashi T,Sakashita F,Tanaka Y

    更新日期:2008-06-01 00:00:00

  • Difficulty in the management of pregnancy after vaginal radical trachelectomy.

    abstract:BACKGROUND:We have performed 26 vaginal radical trachelectomies (RTs) for patients with early invasive uterine cervical cancer since 2003 and, to date, have experienced 8 deliveries. The procedure has a high risk for preterm labor and the subsequent occurrence of preterm premature rupture of membranes (pPROM). We repor...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-012-0479-4

    authors: Takada S,Ishioka S,Endo T,Baba T,Morishita M,Akashi Y,Mizuuchi M,Adachi H,Kim M,Saito T

    更新日期:2013-12-01 00:00:00

  • Effect of calcium and magnesium on neurotoxicity and blood platinum concentrations in patients receiving mFOLFOX6 therapy: a prospective randomized study.

    abstract:BACKGROUND:Whether the administration of calcium (Ca) and magnesium (Mg) can reduce oxaliplatin-related neurotoxicity remains controversial. In addition, little is known about the effects of Ca/Mg on the blood level of platinum or objective tumor progression. PATIENTS AND METHODS:Patients receiving modified FOLFOX6 fo...

    journal_title:International journal of clinical oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s10147-009-0015-3

    authors: Ishibashi K,Okada N,Miyazaki T,Sano M,Ishida H

    更新日期:2010-02-01 00:00:00

  • Bilateral primary malignant lymphoma of the ureter.

    abstract::We report the case of a 68-year-old Japanese man who presented with postrenal azotemia due to bilateral upper ureteral stenosis. The patient's right kidney was nonfunctional; therefore, right nephroureterectomy was performed for the purpose of pathologic diagnosis. Histopathologic examination revealed follicular lymph...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-007-0685-7

    authors: Kubota Y,Kawai A,Tsuchiya T,Kozima K,Yokoi S,Deguchi T

    更新日期:2007-12-01 00:00:00

  • Effect of postoperative radiotherapy on survival in duodenal adenocarcinoma: a propensity score-adjusted analysis of Surveillance, Epidemiology, and End Results database.

    abstract:PURPOSE:The use of adjuvant treatment has not been sufficiently investigated in duodenal adenocarcinoma. This study evaluated the effect of postoperative radiotherapy (PORT) on survival outcomes in this rare malignancy. METHODS:We identified patients who were diagnosed between 2004 and 2013 in the Surveillance, Epidem...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-017-1226-7

    authors: Lim YJ,Kim K

    更新日期:2018-06-01 00:00:00

  • Comparison of chemotherapeutic efficacy between LCNEC diagnosed using large specimens and possible LCNEC diagnosed using small biopsy specimens.

    abstract:BACKGROUND:It is often difficult to diagnose large cell neuroendocrine carcinomas (LCNEC) of the lung using small biopsy specimens. Some recent studies attempted to diagnose LCNEC using biopsy specimens; in 2011, the International Association for the Study of Lung Cancer pathological panels suggested possible LCNEC as ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-012-0509-2

    authors: Tokito T,Kenmotsu H,Watanabe R,Ito I,Shukuya T,Ono A,Nakamura Y,Tsuya A,Naito T,Murakami H,Takahashi T,Ohde Y,Kondo H,Endo M,Kameya T,Nakajima T,Mori K,Yamamoto N

    更新日期:2014-02-01 00:00:00

  • Optimal use of anthracycline-free perioperative chemotherapy in HER2-positive breast cancer patients.

    abstract:PURPOSE:In adjuvant settings of human epidermal growth factor receptor 2 (HER2)-positive breast cancer, anthracycline-based chemotherapy followed by taxane and trastuzumab is a standard regimen. Recent studies have reported the use of anthracycline-free adjuvant chemotherapy in selected HER2-positive breast cancer pati...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-019-01420-2

    authors: Watanuki R,Hayashida T,Kawai Y,Kikuchi M,Nakashoji A,Yokoe T,Toyota T,Seki T,Takahashi M,Kitagawa Y

    更新日期:2019-07-01 00:00:00

  • A recurrence-predicting prognostic factor for patients with ovarian clear-cell adenocarcinoma at reproductive age.

    abstract:OBJECTIVES:We retrospectively analyzed the clinicopathological features and evaluated the prognostic indicators of recurrence in 132 patients with clear cell adenocarcinoma (CCC) of the ovary at reproductive age. PATIENTS AND METHODS:Between 1986 and 2011, as a regional population-based study, clinicopathological data...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0645-3

    authors: Kajiyama H,Mizuno M,Shibata K,Umezu T,Suzuki S,Yamamoto E,Mitsui H,Sekiya R,Niimi K,Kawai M,Nagasaka T,Kikkawa F

    更新日期:2014-10-01 00:00:00

  • Multiple lymphomatous polyposis overexpressing cyclin D1.

    abstract::A case of mantle cell lymphoma (MCL) associated with multiple lymphomatous polyposis (MLP) is reported is a 62-year-old woman, with special reference to the patient's clinical features and response to treatment. There were multiple widespread polypoid lesions in the entire gastrointestinal tract, with ileocecal masses...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s101470050012

    authors: Tsujimura H,Takagi T,Tamaru J,Sakai C

    更新日期:2000-02-01 00:00:00

  • Prognostic outcomes and safety in patients treated with pembrolizumab for advanced urothelial carcinoma: experience in real-world clinical practice.

    abstract:BACKGROUND:Prognostic outcomes and safety following treatment with pembrolizumab in patients with advanced urothelial carcinoma (UC) have not been fully elucidated in clinical practice. The aim of this study was to evaluate the oncological efficacy and safety of pembrolizumab after failure of platinum-based chemotherap...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-019-01613-9

    authors: Tamura D,Jinnouchi N,Abe M,Ikarashi D,Matsuura T,Kato R,Maekawa S,Kato Y,Kanehira M,Takata R,Obara W

    更新日期:2020-05-01 00:00:00

  • Juvenile granulosa cell tumor of the ovary presenting with pleural effusion and ascites.

    abstract::Juvenile granulosa cell tumor (GCT) is a rare tumor, and the majority (90%) are reported in the prepubertal or under-30-year age group, in contrast to the adult type, which is more common in the fifth decade. On histopathological examination, juvenile GCTs are distinct from the adult type of GCT, and have a lower risk...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-008-0805-z

    authors: Kaur H,Bagga R,Saha SC,Gainder S,Srinivasan R,Adhya AK,Dhaliwal LK

    更新日期:2009-02-01 00:00:00

  • Malignant Brenner tumor of the ovary: analysis of 13 cases.

    abstract:OBJECTIVE:Most Brenner tumors are benign, with only 1% being malignant. In this study we report on 13 cases with malignant Brenner tumor of the ovary and discuss the clinical, demographic and histologic features. METHOD:Thirteen patients with malignant Brenner tumor of the ovary who were treated at Selçuk University G...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-011-0290-7

    authors: Gezginç K,Karatayli R,Yazici F,Acar A,Çelik Ç,Çapar M,Tavli L

    更新日期:2012-08-01 00:00:00

  • A phase I/II study on stereotactic body radiotherapy with real-time tumor tracking using CyberKnife based on the Monte Carlo algorithm for lung tumors.

    abstract:BACKGROUND:In this phase I/II study, we assessed the safety and initial efficacy of stereotactic body radiotherapy (SBRT) for lung tumors with real-time tumor tracking using CyberKnife based on the Monte Carlo algorithm. METHODS:Study subjects had histologically confirmed primary non-small-cell lung cancer staged as T...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-017-1123-0

    authors: Iwata H,Ishikura S,Murai T,Iwabuchi M,Inoue M,Tatewaki K,Ohta S,Yokota N,Shibamoto Y

    更新日期:2017-08-01 00:00:00

  • A matched-pair comparison of intensity-modulated radiation therapy with cetuximab versus intensity-modulated radiation therapy with platinum-based chemotherapy for locally advanced head neck cancer.

    abstract:PURPOSE:We retrospectively compared the efficacy of intensity-modulated radiotherapy (IMRT) and cetuximab (IMRT/cetuximab) versus IMRT and platinum-based chemotherapy (IMRT/platinum) for locally advanced head neck squamous cell carcinoma (LAHNSCC). METHODS:Thirty-one IMRT/cetuximab patients were matched 1:2 with 62 IM...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0540-y

    authors: Huang J,Baschnagel AM,Chen P,Gustafson G,Jaiyesmi I,Folbe M,Ye H,Akervall J,Krauss D

    更新日期:2014-04-01 00:00:00

  • Use of preoperative performance status and hemoglobin concentration to predict overall survival for patients aged ≥ 75 years after radical cystectomy for treatment of bladder cancer.

    abstract:BACKGROUND:The standard of care for treatment of localized muscle-invasive bladder cancer (MIBC) is radical cystectomy (RC). The patient's condition may affect management of MIBC, especially for elderly patients with more comorbid conditions and lower performance status. We retrospectively evaluated the association bet...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-015-0857-9

    authors: Hara T,Matsuyama H,Kamiryo Y,Hayashida S,Yamamoto N,Nasu T,Joko K,Baba Y,Suga A,Yamamoto M,Aoki A,Takai K,Yoshihiro S,Konishi M,Sakano S,Imoto K,Tei Y,Yamaguchi S,Yano S,Yamaguchi Uro-Onocology Group.

    更新日期:2016-02-01 00:00:00

  • Combination of hemoglobin, alkaline phosphatase, and age predicts optimal docetaxel regimen for patients with castration-resistant prostate cancer.

    abstract:BACKGROUND:We aimed to find the prognostic factors predicting overall survival (OS) in patients with castration-resistant prostate cancer (CRPC) who had docetaxel (DTX) chemotherapy, and to construct a model predicting the optimum number of cycles of DTX. METHODS:A total of 279 CRPC patients who received DTX (≥50 mg/m...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0638-2

    authors: Matsuyama H,Shimabukuro T,Hara I,Kohjimoto Y,Suzuki K,Koike H,Uemura H,Hayashi T,Ueno M,Kodaira K,Tomita Y,Sakurai T,Shimizu N

    更新日期:2014-10-01 00:00:00

  • Primary retroperitoneal mucinous cystadenocarcinoma with mural nodules: a case report and literature review.

    abstract::A primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is an extremely rare lesion. To date, only 49 cases have been reported. The presence of mural nodules in a PRMC may indicate a worse prognosis. We report the case of a 40-year-old Japanese woman with a PRMC with mural nodules. Microscopic examination reveale...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-011-0313-4

    authors: Kanayama T,Yoshino K,Enomoto T,Ohashi H,Fujita M,Ueda Y,Kimura T,Kobayashi E,Morii E,Kimura T

    更新日期:2012-08-01 00:00:00

  • Value of free-to-total prostate-specific antigen ratio for detection and staging of prostate cancer.

    abstract::Background. We aimed to evaluate the clinical usefulness of measurement of the free-to-total (F/T) ratio of prostate-specific antigen (PSA) for the differentiation of prostate cancer from benign prostate hyperplasia (BPH) and for the staging of prostate cancer. Values for PSA density (PSAD) and PSAD adjusted to the tr...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s101470050002

    authors: Furuya Y,Akakura K,Ito H

    更新日期:2000-02-01 00:00:00

  • Sequential chemotherapy using gemcitabine + carboplatin followed by gemcitabine + carboplatin + docetaxel for advanced upper-tract urothelial cancer.

    abstract:BACKGROUND:Retrospective evaluation of the effectiveness and adverse events (AEs) of a sequential chemotherapy regimen using gemcitabine + carboplatin (GCarbo) followed by GCarbo + docetaxel (GCarboD) for advanced upper-tract urothelial carcinoma (UTUC). METHODS:We treated 56 patients with advanced UTUC. Mean patient ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-015-0846-z

    authors: Yoneyama T,Imai A,Hatakeyama S,Hashimoto Y,Koie T,Ohyama C

    更新日期:2015-12-01 00:00:00

  • Weekly, low-dose docetaxel combined with estramustine for Japanese castration-resistant prostate cancer: its efficacy and safety profile compared with tri-weekly standard-dose treatment.

    abstract:BACKGROUND:We retrospectively investigated the efficacy and safety profile of weekly low-dose docetaxel (DTX) with estramustine in comparison with triweekly standard-dose DTX treatment for Japanese patients with castration-resistant prostate cancer (CRPC). METHODS:Between April 2002 and January 2011, 75 CRPC patients ...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s10147-013-0536-7

    authors: Nakai Y,Nishimura K,Nakayama M,Uemura M,Takayama H,Nonomura N,Tsujimura A,Osaka CRPC Clinical Study Collaboration.

    更新日期:2014-02-01 00:00:00

  • Efficacies and safety of neoadjuvant gemcitabine plus carboplatin followed by immediate cystectomy in patients with muscle-invasive bladder cancer, including those unfit for cisplatin: a prospective single-arm study.

    abstract:BACKGROUND:Neoadjuvant cisplatin-based chemotherapy for patients with muscle-invasive bladder cancer (BC) has better survival benefit than radical cystectomy (RC) alone. However, optimal dosing schedule, including drug selection, number of cycles, and interval between chemotherapy and cystectomy, as well as acceptable ...

    journal_title:International journal of clinical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10147-012-0447-z

    authors: Koie T,Ohyama C,Hashimoto Y,Hatakeyama S,Yamamoto H,Yoneyama T,Kamimura N

    更新日期:2013-08-01 00:00:00

  • Platelet-sparing effect of paclitaxel in heavily pretreated ovarian cancer patients.

    abstract::Carboplatin has proven to be effective in the treatment of patients with recurrent ovarian cancer who have responded to platinum-based first-line chemotherapy. However, thrombocytopenia is a problem in heavily pretreated patients. Paclitaxel has a so-called platelet-sparing effect, but until now it was unknown whether...

    journal_title:International journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s101470200050

    authors: Ishikawa H,Fujiwara K,Suzuki S,Tanaka Y,Kohno I

    更新日期:2002-10-01 00:00:00