Abstract:
:A primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is an extremely rare lesion. To date, only 49 cases have been reported. The presence of mural nodules in a PRMC may indicate a worse prognosis. We report the case of a 40-year-old Japanese woman with a PRMC with mural nodules. Microscopic examination revealed that the stromal cells of the nodules were spindle-shaped and varied in size. The nodules were immunoreactive for vimentin but negative for cytokeratin and EMA, and the nuclei of the stromal cells were pleomorphic and strongly Ki-67 immunoreactive. The nodules were diagnosed as true sarcoma. To the best of our knowledge, this is 11th published case report of a PRMC with mural nodules.
journal_name
Int J Clin Oncoljournal_title
International journal of clinical oncologyauthors
Kanayama T,Yoshino K,Enomoto T,Ohashi H,Fujita M,Ueda Y,Kimura T,Kobayashi E,Morii E,Kimura Tdoi
10.1007/s10147-011-0313-4subject
Has Abstractpub_date
2012-08-01 00:00:00pages
407-11issue
4eissn
1341-9625issn
1437-7772journal_volume
17pub_type
杂志文章abstract:BACKGROUND:The CpG island methylator phenotype (CIMP) with multiple promoter methylated loci has been observed in a subset of human colorectal cancer (CRC) cases. CIMP status, which is closely associated with specific clinicopathological and molecular characteristics, is considered a potential predictive biomarker for ...
journal_title:International journal of clinical oncology
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