Analysis and treatment of 45 platinum-allergic gynecologic malignant tumors.

abstract：:A case of mantle cell lymphoma (MCL) associated with multiple lymphomatous polyposis (MLP) is reported is a 62-year-old woman, with special reference to the patient's clinical features and response to treatment. There were multiple widespread polypoid lesions in the entire gastrointestinal tract, with ileocecal masses...

journal_title：International journal of clinical oncology

authors： Tsujimura H,Takagi T,Tamaru J,Sakai C

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Invasive micropapillary carcinoma (IMPC) is a relatively rare subtype of gastric adenocarcinoma and has aggressive histopathologic characteristics, including lymphatic and vascular invasion. However, the associated long-term survival outcomes remain unclear. This study aimed to compare the clinicopathologica...

journal_title：International journal of clinical oncology

authors： Kano M,Hihara J,Kaneko M,Uemura K,Ohge H,Sueda T

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Phase I study of weekly administration of low-dose docetaxel/cisplatin concurrent with conventionally fractionated radiotherapy for locally advanced head and neck squamous cell carcinoma suggested the recommended dose of docetaxel at 10 mg/m2 and cisplatin at 20 mg/m2. Phase II study of the concurrent chemor...

journal_title：International journal of clinical oncology

authors： Nakahara S,Takenaka Y,Ogawa K,Nishiike S,Yamamoto Y,Seo Y,Isohashi F,Suzuki O,Yoshioka Y,Sumida I,Yoshii T,Tomiyama Y,Inohara H

更新日期：2016-12-01 00:00:00

abstract：:Research misconduct and fraud in clinical research is an increasing problem facing the scientific community. This problem is expected to increase due to discoveries in central statistical monitoring and with the increase in first-time clinical trial investigators in the increasingly global reach of oncology clinical t...

journal_title：International journal of clinical oncology

authors： Herson J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Detailed information is not currently available on the incidence, natural course, and management of asymptomatic abnormal prostate findings incidentally detected by radiologic evaluations after BCG therapy for non-muscle-invasive bladder cancer patients. METHODS:We identified 38 patients who were evaluated ...

journal_title：International journal of clinical oncology

authors： Matsushima M,Kikuchi E,Akita H,Miyajima A,Oya M,Jinzaki M

更新日期：2017-06-01 00:00:00

abstract：:Adenoid cystic carcinoma of the uterine cervix is a rare and peculiar variant of adenocarcinoma. This tumor represents 3% of all primary cervical adenocarcinomas, and it is locally aggressive and capable of metastasis to other organs even in its early stage. We report a case of adenoid cystic carcinoma stage IIIb that...

journal_title：International journal of clinical oncology

authors： Nishida M,Nasu K,Takai N,Miyakawa I,Kashima K

更新日期：2005-06-01 00:00:00

abstract：:Recent advances in molecular biology have identified the responsible genes for many hereditary cancer syndromes (familial tumors). Therefore, now, the final diagnosis of familial tumors can be done by molecular methods to detect the genetic alteration in the disease-causing responsible gene(s) in the patient. So-calle...

journal_title：International journal of clinical oncology

authors： Tomita N,Oto M

更新日期：2004-08-01 00:00:00

abstract：:It is well known that the expression of anticancer drug-resistant factors is elevated in patients with primary refractory or relapsed chronic lymphocytic leukemia (CLL) who have been treated with chemotherapy. We report here two C(H)OP refractory patients with CLL in whom salvage chemotherapy chosen by evaluating anti...

journal_title：International journal of clinical oncology

authors： Matsunaga T,Kogawa K,Fujimi A,Takizawa K,Takahira N,Takemoto N,Tanaka I,Akiyama T,Sato T,Takayama T,Terui T,Sakamaki S,Niitsu Y

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Trachelectomy was developed as a fertility-sparing surgery for early-stage cervical cancer in patients of childbearing age. The purpose of this study is to evaluate oncologic and obstetric outcomes and complications after abdominal trachelectomy. METHODS:We began to perform abdominal trachelectomy in 2005. ...

journal_title：International journal of clinical oncology

authors： Okugawa K,Kobayashi H,Sonoda K,Kaneki E,Kawano Y,Hidaka N,Egashira K,Fujita Y,Yahata H,Kato K

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Although several studies have reported the incidence of KIT and PDGFRA gene mutations in cutaneous melanomas of Caucasians, only one report is available for Mongoloids, including Japanese. In Japan, melanoma is an uncommon neoplasm compared with countries with Caucasian populations. METHODS:In this study, p...

journal_title：International journal of clinical oncology

authors： Terada T

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Obese women with estrogen receptor (ER)-positive breast cancer may experience worse disease-free and overall survival. We hypothesize that this observation is due to intrinsically aggressive disease and that obesity will be associated with higher histologic grade and Ki67. METHODS:A sequential cohort of wom...

journal_title：International journal of clinical oncology

authors： Santa-Maria CA,Yan J,Xie XJ,Euhus DM

更新日期：2015-04-01 00:00:00

abstract：:In Japan, the first actual survey of morbidity from cancer was conducted by Dr. Mitsuo Segi in Miyagi Prefecture from 1951 to 1953. Population-based cancer registries were started in 1957 in Hiroshima and 1958 in Nagasaki for the follow-up of survivors of the atomic bombings. Public population-based cancer registries,...

journal_title：International journal of clinical oncology

authors： Okamoto N

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate prognostic factors and develop a prognostic factor-based risk stratification model for disease-specific survival (DSS) in a radical cystectomy (RC) series. METHODS:The patient cohort comprised 194 consecutive patients with bladder cancer treated with RC. Univariate a...

journal_title：International journal of clinical oncology

authors： Gondo T,Nakashima J,Ozu C,Ohno Y,Horiguchi Y,Namiki K,Yoshioka K,Ohori M,Hatano T,Tachibana M

更新日期：2012-10-01 00:00:00

abstract：:Distant metastasis from colorectal carcinoma most often occurs in the liver and lungs. Metastasis to bones, adrenals, lymph nodes, brain, and skin has also been reported. Metastatic colorectal carcinoma to the testes is very uncommon. Even more uncommon is testicular metastasis from rectal carcinoma. Researchers throu...

journal_title：International journal of clinical oncology

authors： Hatoum HA,Abi Saad GS,Otrock ZK,Barada KA,Shamseddine AI

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Opioids are key drugs for cancer pain relief, but some patients, especially those who have gastroenterological cancers, suffer from severe opioid-induced bowel dysfunction (OBD), which reduces their quality of life. In order to achieve better pain relief, efforts to minimize OBD are required. METHODS:Betwee...

journal_title：International journal of clinical oncology

authors： Matsui T,Kojima T,Kojima H,Iwamoto N,Kure S,Uemura T,Fujimitsu Y,Sakamoto J

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Positron Emission Tomography-Computed Tomography (PET-CT) has been changing diagnostic and therapeutic strategies for patients with cancers, and several PET-CT-related prognostic factors have been reported. We have focused on metabolic tumor volumes (MTVs) over the whole body and in specific organs using 18F...

journal_title：International journal of clinical oncology

authors： Yamanaka S,Miyagawa M,Sugawara Y,Hasebe S,Fujii T,Takeuchi K,Tanaka K,Yakushijin Y

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Our aim was to study the efficacy and safety of combination chemotherapy with gemcitabine plus cisplatin (GC) for patients with advanced urothelial carcinoma (UC) after failure of methotrexate, vinblastin, adriamycin, and cisplatin (M-VAC) chemotherapy. METHODS:We studied a total of 33 patients with advance...

journal_title：International journal of clinical oncology

authors： Gondo T,Ohori M,Hamada R,Tanaka A,Satake N,Takeuchi H,Nakashima J,Hatano T,Tachibana M

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:We aimed to find the prognostic factors predicting overall survival (OS) in patients with castration-resistant prostate cancer (CRPC) who had docetaxel (DTX) chemotherapy, and to construct a model predicting the optimum number of cycles of DTX. METHODS:A total of 279 CRPC patients who received DTX (≥50 mg/m...

journal_title：International journal of clinical oncology

authors： Matsuyama H,Shimabukuro T,Hara I,Kohjimoto Y,Suzuki K,Koike H,Uemura H,Hayashi T,Ueno M,Kodaira K,Tomita Y,Sakurai T,Shimizu N

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:We aimed to determine the safety and efficacy of monthly paclitaxel and carboplatin with oral estramustine phosphate in patients with hormone-refractory prostate cancer (HRPC). METHODS:Patients with prostate cancer that was progressing despite androgen ablation therapy were treated with i.v. paclitaxel, 175...

journal_title：International journal of clinical oncology

authors： Segawa T,Kamoto T,Kinoshita H,Kunishima Y,Yoshimura K,Ito A,Takahashi T,Higashi S,Nakamura E,Nishiyama H,Ito N,Yamamoto S,Habuchi T,Ogawa O

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Data supporting the safety and feasibility of laparoscopic total proctocolectomy with ileal pouch-anal anastomosis (TPC-IPAA) and total colectomy with ileorectal anastomosis (TC-IRA) for patients with familial adenomatous polyposis (FAP) are limited. The aim of this study was to clarify the feasibility and m...

journal_title：International journal of clinical oncology

authors： Konishi T,Ishida H,Ueno H,Kobayashi H,Hinoi T,Inoue Y,Ishida F,Kanemitsu Y,Yamaguchi T,Tomita N,Matsubara N,Watanabe T,Sugihara K

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The optimal treatment for elderly patients with glioblastoma has not been established. METHODS:We retrospectively analyzed the safety and efficacy of hypofractionated radiotherapy (45 Gy/15 fr) combined with temozolomide (TMZ) followed by bevacizumab (BEV) salvage treatment in 18 glioblastoma patients aged ...

journal_title：International journal of clinical oncology

authors： Matsuda KI,Sakurada K,Nemoto K,Kayama T,Sonoda Y

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate whether serum alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) trends might be correlated with overall survival rates in patients with recurrent hepatocellular carcinoma (HCC) undergoing trans-catheter arterial chemo-embolization (TACE). METHODS:We pe...

journal_title：International journal of clinical oncology

authors： Arai T,Kobayashi A,Ohya A,Takahashi M,Yokoyama T,Shimizu A,Motoyama H,Furusawa N,Notake T,Kitagawa N,Sakai H,Imamura H,Kadoya M,Miyagawa S

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The standard treatment for cervical cancer is chemoradiation although some patients showed treatment resistance. The purpose of this study was to investigate the clinical efficacy of surgery after chemoradiation for cervical cancer. METHODS:Patients with FIGO stage IB2 to IIB cervical cancer were included i...

journal_title：International journal of clinical oncology

authors： Yoshida K,Kajiyama H,Yoshihara M,Tamauchi S,Ikeda Y,Yoshikawa N,Nishino K,Niimi K,Suzuki S,Kikkawa F

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The efficacy of direct oral anti-coagulants (DOACs) for the treatment of venous thromboembolism (VTE) in Japanese patients with advanced cancer is largely unknown. METHODS:This prospective single-center observational study enrolled Japanese patients with unresectable advanced cancer who started DOAC treatme...

journal_title：International journal of clinical oncology

authors： Oyakawa T,Muraoka N,Iida K,Kusuhara M,Mori K

更新日期：2019-07-01 00:00:00

abstract：:Computed tomography (CT) plays an essential role in oncological imaging as the modality of screening for malignancies, mapping out the treatment strategy at staging, assessing response to the treatment, and following up patient outcome after the treatment. The advent of multidetector-row CT (MDCT) has brought about dr...

journal_title：International journal of clinical oncology

authors： Ueda T,Mori K,Minami M,Motoori K,Ito H

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:We performed a multicenter longitudinal study using our neck dissection questionnaire (NDQ) and arm abduction test (AAT) to assess the impact of rehabilitation and surgical modification on postoperative quality of life (QOL). METHODS:Patients who had undergone neck dissection for the treatment of head and n...

journal_title：International journal of clinical oncology

authors： Nibu K,Ebihara Y,Ebihara M,Kawabata K,Onitsuka T,Fujii T,Saikawa M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Neoplastic cardiac tamponade (NCT) is a life-threatening complication of cancer. The interval between cancer diagnosis and NCT onset and the prognosis after pericardiocentesis may differ according to cancer type. METHODS AND RESULTS:We performed a retrospective study of 113 patients (54 % male) with NCT who...

journal_title：International journal of clinical oncology

authors： Takayama T,Okura Y,Okada Y,Honma K,Nashimoto A,Sato N,Yokoyama A,Minamino T

更新日期：2015-10-01 00:00:00

abstract：:We report two cases of the plasmacytoid variant of urothelial carcinoma of urinary bladder in which systemic chemotherapy was effective. In the first case, a 76-year-old man presented with dysphasia. Magnetic resonance imaging (MRI) and computed tomography revealed a brain tumor and a bladder tumor. Resection of the b...

journal_title：International journal of clinical oncology

authors： Hayashi T,Tanigawa G,Fujita K,Imamura R,Nakazawa S,Yamamoto Y,Hosomi M,Shimazu K,Fushimi H,Yamaguchi S

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the role of Bcl-2 protein and adrenomedullin (AM) expression in relation to apoptosis in the neoplastic changes of squamous epithelium of the uterine cervix. METHODS:Apoptosis in sections of normal cervical epithelium, cervical intraepithelial neoplasia (CIN), and i...

journal_title：International journal of clinical oncology

authors： Li Z,Takeuchi S,Ohara N,Maruo T

更新日期：2003-04-01 00:00:00

abstract：:Complex carbohydrates are major components of the cell membrane and they play crucial roles in cell-cell and cell-extracellular matrix interactions, as well as in signal transduction. They consist of three kinds of molecular species; glycoproteins, proteoglycans, and glycosphingolipids. There is a distinct difference ...

journal_title：International journal of clinical oncology

authors： Ohyama C

更新日期：2008-08-01 00:00:00