Quality of life after neck dissection: a multicenter longitudinal study by the Japanese Clinical Study Group on Standardization of Treatment for Lymph Node Metastasis of Head and Neck Cancer.

abstract：BACKGROUND:The Randomized Phase III Study Comparing Oxaliplatin plus S-1 with Cisplatin plus S-1 in Chemotherapy-naïve Patients with Advanced Gastric Cancer (G-SOX) showed the noninferiority of S-1 (an oral fluoropyrimidine-derivative dihydropyrimidine dehydrogenase inhibitor) plus oxaliplatin combination therapy (SOX)...

journal_title：International journal of clinical oncology

authors： Hamada C,Yamada Y,Azuma M,Nishikawa K,Gotoh M,Bando H,Sugimoto N,Nishina T,Amagai K,Chin K,Niwa Y,Tsuji A,Imamura H,Tsuda M,Yasui H,Fujii H,Yamaguchi K,Yasui H,Hironaka S,Shimada K,Miwa H,Hyodo I

更新日期：2016-08-01 00:00:00

abstract：:We report the case of a 65-year-old man with recurrent prostate cancer who presented with meningeal carcinomatosis. In September 2007, he had been diagnosed with mixed type small cell carcinoma and adenocarcinoma at clinical stage T4N1M1 (primary prostate tumor with multiple bone, liver, and lymph node metastases) and...

journal_title：International journal of clinical oncology

authors： Yamada T,Ohtsubo K,Mouri H,Yamashita K,Yasumoto K,Izumi K,Zen Y,Watanabe H,Yano S

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:We evaluated the association between subclinical interstitial lung disease (ILD) and fatal radiation pneumonitis (RP) in patients with thoracic tumors treated with thoracic radiotherapy (RT). METHODS:Sixty-two consecutive patients with thoracic tumors treated with thoracic RT were retrospectively analyzed. ...

journal_title：International journal of clinical oncology

authors： Yamaguchi S,Ohguri T,Matsuki Y,Yahara K,Oki H,Imada H,Narisada H,Korogi Y

更新日期：2015-02-01 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs)-such as antibodies to programmed cell death-1 (PD-1), to its ligand PD-L1, or to cytotoxic T lymphocyte-associated protein-4 (CTLA-4)-are an evolving treatment option for several types of cancer, but only a limited number of patients benefit from such therapy. Preclinical studies ha...

journal_title：International journal of clinical oncology

authors： Hayashi H,Nakagawa K

更新日期：2020-05-01 00:00:00

abstract：:The updated 2016 World Health Organization (WHO) Classification of Tumours of the Central Nervous System (CNS) has incorporated molecular parameters into pathological diagnosis, for the first time in the molecular era. While it has led to the more precise diagnoses of well-understood entities and the better comprehens...

journal_title：International journal of clinical oncology

authors： Onizuka H,Masui K,Komori T

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarker...

journal_title：International journal of clinical oncology

authors： Ruggiero A,De Rosa G,Rizzo D,Leo A,Maurizi P,De Nisco A,Vendittelli F,Zuppi C,Mordente A,Riccardi R

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:It is expected that cell-free and concentrated ascites reinfusion therapy (CART) will relieve the symptoms caused by ascites. To date, however, no report of objective changes in patients' symptoms has been published. We have therefore evaluated symptom management by CART. METHODS:From April 2011 to July 201...

journal_title：International journal of clinical oncology

authors： Ito T,Hanafusa N,Iwase S,Noiri E,Nangaku M,Nakagawa K,Miyagawa K

更新日期：2015-06-01 00:00:00

abstract：:Poorly differentiated neuroendocrine carcinoma has a poor prognosis, especially when associated with distant metastasis. A 60-year-old man was admitted to a private hospital because of dyspnea at work in 2007. Computed tomography revealed lung infarction and a right adrenal tumor sized 12 cm in diameter that was tight...

journal_title：International journal of clinical oncology

authors： Ochiai T,Komiyama S,Ikoma H,Kubota T,Nakanishi M,Ichikawa D,Kikuchi S,Fujiwara H,Sakakura C,Kokuba Y,Sonoyama T,Otsuji E

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Enlarged pelvic nodes are commonly found during preoperative imaging studies in cervical cancer patients and may represent tumor metastasis. It remains controversial whether debulking of these enlarged nodes prior to definitive radiotherapy offers any survival benefit to the patient. METHODS:Enlarged suspic...

journal_title：International journal of clinical oncology

authors： Cheung TH,Lo KW,Yim SF,Yau SH,Yu MM,Yeung WK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the prognostic role of the pretreatment neutrophil-to-lymphocyte ratio (NLR) as a predictive marker prior to treatment of cervical cancer with radiation therapy (RT) alone or concurrent chemoradiation therapy (CCRT). METHODS:Fifty-six patients with squamous cell carc...

journal_title：International journal of clinical oncology

authors： Mizunuma M,Yokoyama Y,Futagami M,Aoki M,Takai Y,Mizunuma H

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Prognostic outcomes and safety following treatment with pembrolizumab in patients with advanced urothelial carcinoma (UC) have not been fully elucidated in clinical practice. The aim of this study was to evaluate the oncological efficacy and safety of pembrolizumab after failure of platinum-based chemotherap...

journal_title：International journal of clinical oncology

authors： Tamura D,Jinnouchi N,Abe M,Ikarashi D,Matsuura T,Kato R,Maekawa S,Kato Y,Kanehira M,Takata R,Obara W

更新日期：2020-05-01 00:00:00

abstract：:Stereotactic body radiation therapy (SBRT) can yield excellent local tumor control, as well as survival benefit comparable to that of surgery for early-stage lung cancer. However, in terms of toxicity, SBRT might lead to fatal radiation pneumonitis. Lung diseases, such as chronic obstructive pulmonary disease (COPD) a...

journal_title：International journal of clinical oncology

authors： Doi H,Nakamatsu K,Nishimura Y

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The efficacy of direct oral anti-coagulants (DOACs) for the treatment of venous thromboembolism (VTE) in Japanese patients with advanced cancer is largely unknown. METHODS:This prospective single-center observational study enrolled Japanese patients with unresectable advanced cancer who started DOAC treatme...

journal_title：International journal of clinical oncology

authors： Oyakawa T,Muraoka N,Iida K,Kusuhara M,Mori K

更新日期：2019-07-01 00:00:00

abstract：:We report the case of a 62-year-old man with advanced gastric cancer and multiple liver metastases who was successfully treated with combined chemotherapy including S-1. The patient was clinically diagnosed with stage IV (T3 N2 H1 P0) disease and was initially treated with 100 mg/body per day S-1 administered orally f...

journal_title：International journal of clinical oncology

authors： Nakamura R,Saikawa Y,Kumagai K,Kiyota T,Ohashi M,Yoshida M,Kubota T,Kumai K,Kitajima M

更新日期：2007-08-01 00:00:00

abstract：:Prostate cancer is androgen-dependent, and hormone therapy, mainly achieved by androgen deprivation, has been one of the main treatment modalities in the clinical management of prostate cancer patients for more than six decades. In the 1980s, luteinizing hormone-releasing hormone agonists, which reduce testosterone to...

journal_title：International journal of clinical oncology

authors： Suzuki H,Kamiya N,Imamoto T,Kawamura K,Yano M,Takano M,Utsumi T,Naya Y,Ichikawa T

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Cancer patients are at high risk of developing a second cancer after the treatment of initial cancers. Understanding the characteristics of multiple primary cancer is important to establish an effective surveillance program for the early detection of second cancers. METHODS:We analyzed the cancer registry r...

journal_title：International journal of clinical oncology

authors： Ueno M,Muto T,Oya M,Ota H,Azekura K,Yamaguchi T

更新日期：2003-06-01 00:00:00

abstract：:Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive malignant tumor arising from the distal collecting tubules which has been shown to have a poor response to several kinds of systemic therapy. We present a case of metastatic CDC that responded favorably to a multiple tyrosine kinase inhibitor, suni...

journal_title：International journal of clinical oncology

authors： Miyake H,Haraguchi T,Takenaka A,Fujisawa M

更新日期：2011-04-01 00:00:00

abstract：:Pseudoaneurysm complicating osteochondroma is extremely rare. We describe a pseudoaneurysm in the popliteal fossa of a 21-year-old man, occurring 5 years after apparently incomplete resection of an osteochondroma at that site. We found magnetic resonance imaging and magnetic resonance angiography to be of great diagno...

journal_title：International journal of clinical oncology

authors： Otsuka T,Yonezawa M,Kamiyama F,Matusita Y,Matui N

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:The objective was to evaluate the incidence of second primary malignancies (SPMs) in thyroid cancer patients compared to age- and gender-matched controls without thyroid cancer from the general population of the same region. METHODS:Tampere and Oulu University Hospitals treated 910 patients with well-differ...

journal_title：International journal of clinical oncology

authors： Hakala TT,Sand JA,Jukkola A,Huhtala HS,Metso S,Kellokumpu-Lehtinen PL

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Several factors related to the immune system, such as a history of allergies and virus infections, may be associated with acute lymphoblastic leukemia (ALL). The purpose of this study was to analyze whether the presence of atopic diseases and previous infection with parvovirus B19 and Epstein-Barr virus (EBV...

journal_title：International journal of clinical oncology

authors： da Conceição Nunes J,de Araujo GV,Viana MT,Sarinho ES

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The correlation between treatment-related factors and lung toxicity has not been sufficiently evaluated in salvage radiotherapy. METHODS:Twenty-one patients with recurrent non-small-cell lung cancer (NSCLC) after lobectomy received salvage radiotherapy to a total dose of 46-60 Gy. The effects of radiotherap...

journal_title：International journal of clinical oncology

authors： Uno T,Isobe K,Kawakami H,Ueno N,Kawata T,Yamamoto S,Sekine Y,Iyoda A,Iizasa T,Fujisawa T,Shigematsu N,Ito H

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Resection of hepatocellular carcinoma (HCC) is potentially curative; however, recurrence is common. To date, few or no effective adjuvant therapies have been adequately investigated. This study evaluates the efficacy of adjuvant iodine-131-lipiodol after hepatic resection through the experience of a single-c...

journal_title：International journal of clinical oncology

authors： Chua TC,Saxena A,Chu F,Butler SP,Quinn RJ,Glenn D,Morris DL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the efficacy and safety profile of weekly low-dose docetaxel (DTX) with estramustine in comparison with triweekly standard-dose DTX treatment for Japanese patients with castration-resistant prostate cancer (CRPC). METHODS:Between April 2002 and January 2011, 75 CRPC patients ...

journal_title：International journal of clinical oncology

authors： Nakai Y,Nishimura K,Nakayama M,Uemura M,Takayama H,Nonomura N,Tsujimura A,Osaka CRPC Clinical Study Collaboration.

更新日期：2014-02-01 00:00:00

abstract：:Carboplatin has proven to be effective in the treatment of patients with recurrent ovarian cancer who have responded to platinum-based first-line chemotherapy. However, thrombocytopenia is a problem in heavily pretreated patients. Paclitaxel has a so-called platelet-sparing effect, but until now it was unknown whether...

journal_title：International journal of clinical oncology

authors： Ishikawa H,Fujiwara K,Suzuki S,Tanaka Y,Kohno I

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:In adjuvant settings of human epidermal growth factor receptor 2 (HER2)-positive breast cancer, anthracycline-based chemotherapy followed by taxane and trastuzumab is a standard regimen. Recent studies have reported the use of anthracycline-free adjuvant chemotherapy in selected HER2-positive breast cancer pati...

journal_title：International journal of clinical oncology

authors： Watanuki R,Hayashida T,Kawai Y,Kikuchi M,Nakashoji A,Yokoe T,Toyota T,Seki T,Takahashi M,Kitagawa Y

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The mechanisms underlying cognitive decline after radiotherapy not directed at brain areas remains unclear. We previously suggested that adjuvant breast radiotherapy in breast conservation therapy could lower memory function soon after therapy, and that the process might be partially mediated by plasma inter...

journal_title：International journal of clinical oncology

authors： Shibayama O,Yoshiuchi K,Inagaki M,Matsuoka Y,Yoshikawa E,Sugawara Y,Akechi T,Wada N,Imoto S,Murakami K,Ogawa A,Uchitomi Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The optimal treatment for elderly patients with glioblastoma has not been established. METHODS:We retrospectively analyzed the safety and efficacy of hypofractionated radiotherapy (45 Gy/15 fr) combined with temozolomide (TMZ) followed by bevacizumab (BEV) salvage treatment in 18 glioblastoma patients aged ...

journal_title：International journal of clinical oncology

authors： Matsuda KI,Sakurada K,Nemoto K,Kayama T,Sonoda Y

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Diagnosis of secondary ovarian tumors originating from colorectal cancer has previously been based upon history of malignancy and radiological findings of bilateral masses with a "stained glass appearance." The purpose of this study was to perform a detailed investigation of the radiological and macroscopic ...

journal_title：International journal of clinical oncology

authors： Kato MK,Shida D,Yoneoka Y,Yoshida H,Miyasaka N,Kanemitsu Y,Kato T

更新日期：2020-09-01 00:00:00

abstract：BACKGROUNDS:The presence of ≥5 circulating tumor cells (CTCs) in 7.5 ml blood is a poor prognostic marker in metastatic breast cancer (MBC). However, the role of human epidermal growth factor receptor 2 (HER2) status in CTCs is not known. METHODS:We prospectively assessed the prognostic value of this parameter for pat...

journal_title：International journal of clinical oncology

authors： Hayashi N,Nakamura S,Tokuda Y,Shimoda Y,Yagata H,Yoshida A,Ota H,Hortobagyi GN,Cristofanilli M,Ueno NT

更新日期：2012-04-01 00:00:00

abstract：:We report herein a case of rapidly growing pulmonary carcinosarcoma, a rare and highly malignant lung neoplasm characterized by a biphasic histopathological pattern consisting of both epithelial and sarcomatous components, and we also summarize the clinical features of this entity based on previously reported cases. A...

journal_title：International journal of clinical oncology

authors： Sato S,Koike T,Yamato Y,Yoshiya K,Motono N,Takeshige M,Homma K,Koizumi N,Yokoyama A,Tsukada H

更新日期：2010-06-01 00:00:00