Paradoxically abundant expression of Bcl-2 and adrenomedullin in invasive cervical squamous carcinoma.

abstract：BACKGROUND:Surgical complication rates of total laryngectomy vary according to the preoperative treatments performed and patient factors. Wound complications after salvage laryngectomy following concurrent chemoradiotherapy (CCRT) were analyzed. METHODS:Eighty-six patients who had undergone total laryngectomy for lary...

journal_title：International journal of clinical oncology

authors： Furuta Y,Homma A,Oridate N,Suzuki F,Hatakeyama H,Suzuki K,Nishioka T,Shirato H,Fukuda S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:One reason for the low cancer screening rate in Japan is that people are not concerned about cancer if they do not have symptoms. METHODS:The authors retrospectively analyzed 18,405 cancer patients using hospital-based cancer registry data collected between 2007 and 2013 at the 13 hospitals of Shimane Prefe...

journal_title：International journal of clinical oncology

authors： Nakabayashi N,Hirose M,Suzuki R,Suzumiya J,Igawa M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Microvascular invasion (mvi) is an important risk factor for recurrent hepatocellular carcinoma (HCC), even after curative liver resection or orthotopic liver transplantation. However, mvi is difficult to detect preoperatively. The aim of this study was to clarify the risk factors of postoperative recurrence...

journal_title：International journal of clinical oncology

authors： Imura S,Teraoku H,Yoshikawa M,Ishikawa D,Yamada S,Saito Y,Iwahashi S,Ikemoto T,Morine Y,Shimada M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species stimulate lymphatic metastasis by accelerating epithelial-to-mesenchymal transition and lymphangiogenesis in the tumor microenvironment. Hence, systemic oxidative stress level may correlate with nodal involvement in patients with a malignant tumor. METHODS:We examined 46 patients wit...

journal_title：International journal of clinical oncology

authors： Tsukioka T,Nishiyama N,Iwata T,Nagano K,Tei K,Suehiro S

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:We evaluated the association between subclinical interstitial lung disease (ILD) and fatal radiation pneumonitis (RP) in patients with thoracic tumors treated with thoracic radiotherapy (RT). METHODS:Sixty-two consecutive patients with thoracic tumors treated with thoracic RT were retrospectively analyzed. ...

journal_title：International journal of clinical oncology

authors： Yamaguchi S,Ohguri T,Matsuki Y,Yahara K,Oki H,Imada H,Narisada H,Korogi Y

更新日期：2015-02-01 00:00:00

abstract：:Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive malignant tumor arising from the distal collecting tubules which has been shown to have a poor response to several kinds of systemic therapy. We present a case of metastatic CDC that responded favorably to a multiple tyrosine kinase inhibitor, suni...

journal_title：International journal of clinical oncology

authors： Miyake H,Haraguchi T,Takenaka A,Fujisawa M

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Enlarged pelvic nodes are commonly found during preoperative imaging studies in cervical cancer patients and may represent tumor metastasis. It remains controversial whether debulking of these enlarged nodes prior to definitive radiotherapy offers any survival benefit to the patient. METHODS:Enlarged suspic...

journal_title：International journal of clinical oncology

authors： Cheung TH,Lo KW,Yim SF,Yau SH,Yu MM,Yeung WK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:To investigate the prognostic and therapeutic implications of time to biochemical relapse (BCR) in patients with prostate cancer after radical prostatectomy. METHODS:The records of 3210 consecutive men with prostate cancer who underwent radical prostatectomy between January 1998 and June 2013 were retrospec...

journal_title：International journal of clinical oncology

authors： Pak S,You D,Jeong IG,Kim YS,Hong JH,Kim CS,Ahn H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Cyclin E and p27 play pivotal roles in cancer development and progression. We investigated whether the prognosis in cases of non-small cell lung cancer without lymph node metastases that underwent complete resection could be associated with tissue expression of cyclin E, p27, and Ki-67. METHODS:Tumors from ...

journal_title：International journal of clinical oncology

authors： Takahashi S,Kamata Y,Tamo W,Koyanagi M,Hatanaka R,Yamada Y,Tsushima T,Takaya S,Fukuda I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Opioids are key drugs for cancer pain relief, but some patients, especially those who have gastroenterological cancers, suffer from severe opioid-induced bowel dysfunction (OBD), which reduces their quality of life. In order to achieve better pain relief, efforts to minimize OBD are required. METHODS:Betwee...

journal_title：International journal of clinical oncology

authors： Matsui T,Kojima T,Kojima H,Iwamoto N,Kure S,Uemura T,Fujimitsu Y,Sakamoto J

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:We performed a retrospective study to clarify the outcome of stage IB2-IIB patients with bulky cervical cancer who underwent neoadjuvant chemotherapy (NAC) followed by radical hysterectomy and adjuvant treatment. METHODS:Sixty-five patients with bulky stage IB2-IIB cervical cancer, treated at Tottori Univer...

journal_title：International journal of clinical oncology

authors： Uegaki K,Shimada M,Sato S,Deura I,Naniwa J,Sato S,Oishi T,Itamochi H,Harada T,Kigawa J

更新日期：2014-04-01 00:00:00

abstract：INTRODUCTION:We retrospectively evaluated the blood coagulation activity using the D-dimer level in the early period after gastrectomy and investigated whether postoperative hypercoagulation affects tumor recurrence and long-term survival in gastric cancer patients. METHODS:The study involved 650 patients who underwen...

journal_title：International journal of clinical oncology

authors： Hara K,Aoyama T,Hayashi T,Nakazono M,Nagasawa S,Shimoda Y,Kumazu Y,Numata M,Yamada T,Tamagawa H,Shiozawa M,Morinaga S,Yukawa N,Rino Y,Masuda M,Ogata T,Oshima T

更新日期：2020-04-01 00:00:00

abstract：:Distant metastasis from colorectal carcinoma most often occurs in the liver and lungs. Metastasis to bones, adrenals, lymph nodes, brain, and skin has also been reported. Metastatic colorectal carcinoma to the testes is very uncommon. Even more uncommon is testicular metastasis from rectal carcinoma. Researchers throu...

journal_title：International journal of clinical oncology

authors： Hatoum HA,Abi Saad GS,Otrock ZK,Barada KA,Shamseddine AI

更新日期：2011-06-01 00:00:00

abstract：:We report the case of a 62-year-old man with advanced gastric cancer and multiple liver metastases who was successfully treated with combined chemotherapy including S-1. The patient was clinically diagnosed with stage IV (T3 N2 H1 P0) disease and was initially treated with 100 mg/body per day S-1 administered orally f...

journal_title：International journal of clinical oncology

authors： Nakamura R,Saikawa Y,Kumagai K,Kiyota T,Ohashi M,Yoshida M,Kubota T,Kumai K,Kitajima M

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:An association between inflammation and patient prognosis has been reported in various types of cancer. The aim of this study was to evaluate the influence of preoperative biliary drainage-related inflammation in patients with biliary tract cancer. METHODS:The clinical data of 97 patients who underwent surg...

journal_title：International journal of clinical oncology

authors： Kurahara H,Maemura K,Mataki Y,Sakoda M,Iino S,Kawasaki Y,Arigami T,Uenosono Y,Kijima Y,Shinchi H,Takao S,Natsugoe S

更新日期：2016-10-01 00:00:00

abstract：:We report a rare case of advanced ovarian mucinous adenocarcinoma in a pregnant woman. A 28-year-old pregnant Japanese woman was diagnosed with an ovarian tumor 8 cm in diameter at a local hospital. She was sent to a private hospital at 25 weeks of gestation because of the growing ovarian tumor. Advanced ovarian carci...

journal_title：International journal of clinical oncology

authors： Ishioka S,Hayashi T,Endo T,Baba T,Honma H,Saito T

更新日期：2007-10-01 00:00:00

abstract：:Standard definitive radiotherapy for cervical cancer consists of whole pelvic external beam radiotherapy (EBRT) and intracavitary brachytherapy (ICBT). In Japan, high-dose-rate ICBT (HDR-ICBT) has been utilized in clinical practice for more than 40 years. Several randomized clinical trials demonstrated that HDR-ICBT a...

journal_title：International journal of clinical oncology

authors： Toita T

更新日期：2009-02-01 00:00:00

abstract：:Pseudoaneurysm complicating osteochondroma is extremely rare. We describe a pseudoaneurysm in the popliteal fossa of a 21-year-old man, occurring 5 years after apparently incomplete resection of an osteochondroma at that site. We found magnetic resonance imaging and magnetic resonance angiography to be of great diagno...

journal_title：International journal of clinical oncology

authors： Otsuka T,Yonezawa M,Kamiyama F,Matusita Y,Matui N

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate whether serum alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) trends might be correlated with overall survival rates in patients with recurrent hepatocellular carcinoma (HCC) undergoing trans-catheter arterial chemo-embolization (TACE). METHODS:We pe...

journal_title：International journal of clinical oncology

authors： Arai T,Kobayashi A,Ohya A,Takahashi M,Yokoyama T,Shimizu A,Motoyama H,Furusawa N,Notake T,Kitagawa N,Sakai H,Imamura H,Kadoya M,Miyagawa S

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:We aimed to find the prognostic factors predicting overall survival (OS) in patients with castration-resistant prostate cancer (CRPC) who had docetaxel (DTX) chemotherapy, and to construct a model predicting the optimum number of cycles of DTX. METHODS:A total of 279 CRPC patients who received DTX (≥50 mg/m...

journal_title：International journal of clinical oncology

authors： Matsuyama H,Shimabukuro T,Hara I,Kohjimoto Y,Suzuki K,Koike H,Uemura H,Hayashi T,Ueno M,Kodaira K,Tomita Y,Sakurai T,Shimizu N

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:To determine the indications for post-chemotherapy consolidative surgery in patients with clinical lymph node (LN) metastatic (cN+) urothelial carcinoma (UC). METHODS:Sixty UC patients with measurable cN+ but without detectable systemic visceral/bone dissemination received induction platinum-based chemother...

journal_title：International journal of clinical oncology

authors： Urakami S,Yuasa T,Yamamoto S,Sakura M,Tanaka H,Hayashi T,Uehara S,Inoue Y,Fujii Y,Masuda H,Fukui I,Yonese J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The present study investigated whether treatment with anginex, a novel antiangiogenic peptide, could block re-vascularization after radiation treatment. METHODS:A squamous cell (SCCVII) xenograft tumor mouse model was employed to assess the effects of anginex given post-radiation on tumor growth, microvesse...

journal_title：International journal of clinical oncology

authors： Amano M,Suzuki M,Andoh S,Monzen H,Terai K,Williams B,Song CW,Mayo KH,Hasegawa T,Dings RP,Griffin RJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the screening rate for hepatitis B virus (HBV) infection, which is recommended by some guidelines for the prevention of HBV reactivation, in patients undergoing chemotherapy for malignancy in Japan. METHODS:The study subjects were 3302 patients who had received first...

journal_title：International journal of clinical oncology

authors： Ikeda M,Yamamoto H,Kaneko M,Oshima H,Takahashi H,Umemoto K,Watanabe K,Hashimoto Y,Ohno I,Mitsunaga S,Okusaka T

更新日期：2016-12-01 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs)-such as antibodies to programmed cell death-1 (PD-1), to its ligand PD-L1, or to cytotoxic T lymphocyte-associated protein-4 (CTLA-4)-are an evolving treatment option for several types of cancer, but only a limited number of patients benefit from such therapy. Preclinical studies ha...

journal_title：International journal of clinical oncology

authors： Hayashi H,Nakagawa K

更新日期：2020-05-01 00:00:00

abstract：:We report two cases of the plasmacytoid variant of urothelial carcinoma of urinary bladder in which systemic chemotherapy was effective. In the first case, a 76-year-old man presented with dysphasia. Magnetic resonance imaging (MRI) and computed tomography revealed a brain tumor and a bladder tumor. Resection of the b...

journal_title：International journal of clinical oncology

authors： Hayashi T,Tanigawa G,Fujita K,Imamura R,Nakazawa S,Yamamoto Y,Hosomi M,Shimazu K,Fushimi H,Yamaguchi S

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Resection of hepatocellular carcinoma (HCC) is potentially curative; however, recurrence is common. To date, few or no effective adjuvant therapies have been adequately investigated. This study evaluates the efficacy of adjuvant iodine-131-lipiodol after hepatic resection through the experience of a single-c...

journal_title：International journal of clinical oncology

authors： Chua TC,Saxena A,Chu F,Butler SP,Quinn RJ,Glenn D,Morris DL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:We conducted a study to validate the influence of the systemic immune-inflammation index (SII) on overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) and to verify whether the implementation of the SII in place of neutrophil and platelet counts within the International Metastatic Re...

journal_title：International journal of clinical oncology

authors： Chrom P,Zolnierek J,Bodnar L,Stec R,Szczylik C

更新日期：2019-05-01 00:00:00

abstract：:This review describes the pathological classification of pediatric liver cancer types and subtypes proposed at the recent international symposium (March 2011, Los Angeles, USA) and meetings involving pathologists serving as central reviewers for the Children's Oncology Group, Société Internationale d'Oncologie Pédiatr...

journal_title：International journal of clinical oncology

authors： Tanaka Y,Inoue T,Horie H

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:It is still controversial whether axillary lymph node (ALN) dissection (ALND) can be omitted after negative sentinel lymph node (SLN) biopsy (SLNB) in breast cancer (BC) patients with clinically positive ALNs at presentation treated with neoadjuvant chemotherapy (NAC). The study aim was to analyze whether SL...

journal_title：International journal of clinical oncology

authors： Takei H,Yoshida T,Kurosumi M,Inoue K,Matsumoto H,Hayashi Y,Higuchi T,Uchida S,Ninomiya J,Kubo K,Oba H,Nagai S,Tabei T

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The standard treatment for cervical cancer is chemoradiation although some patients showed treatment resistance. The purpose of this study was to investigate the clinical efficacy of surgery after chemoradiation for cervical cancer. METHODS:Patients with FIGO stage IB2 to IIB cervical cancer were included i...

journal_title：International journal of clinical oncology

authors： Yoshida K,Kajiyama H,Yoshihara M,Tamauchi S,Ikeda Y,Yoshikawa N,Nishino K,Niimi K,Suzuki S,Kikkawa F

更新日期：2020-02-01 00:00:00