Safety of the insulin tolerance test.

Abstract:

:Concerns have been raised about the hazards of the insulin tolerance test (ITT), used to measure growth hormone secretion. In Glasgow, we continue to use this test, adhering to a strict protocol. A review of outcome over a 10 year period (1989-99), during which 550 ITTs were performed, was undertaken. No serious adverse events occurred; in particular, no child fitted or required intravenous glucose. Fewer tests were done during the latter five years, with a higher yield of growth hormone (GH) deficiency, reflecting our increasingly conservative approach to paediatric GH therapy during this period. We conclude that the ITT is safe and reliable in a paediatric setting provided that a strict procedure is followed.

journal_name

Arch Dis Child

authors

Galloway PJ,McNeill E,Paterson WF,Donaldson MD

doi

10.1136/adc.87.4.354

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

354-6

issue

4

eissn

0003-9888

issn

1468-2044

journal_volume

87

pub_type

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