Motor disorders of the oesophagus in gastro-oesophageal reflux.

Abstract:

:Mechanisms of gastro-oesophageal reflux were studied by oesophageal manometry and pH monitoring in 33 children: nine controls, 15 with gastro-oesophageal reflux alone, and nine with reflux oesophagitis. A total of 122 episodes of reflux were analysed in detail: 82 (67%) were synchronous with swallowing and 40 (33%) asynchronous. Infants with trivial symptoms had gastro-oesophageal reflux synchronous with swallowing, whereas those with serious symptoms had slower acid clearance and asynchronous reflux. There were significant differences in lower oesophageal sphincter pressure and amplitude of oesophageal contractions between controls and patients with both gastro-oesophageal reflux and reflux oesophagitis. In reflux oesophagitis there was a decrease in lower oesophageal sphincter pressure and the contractions had a bizarre waveform suggesting a neuropathic process.

journal_name

Arch Dis Child

authors

Mahony MJ,Migliavacca M,Spitz L,Milla PJ

doi

10.1136/adc.63.11.1333

subject

Has Abstract

pub_date

1988-11-01 00:00:00

pages

1333-8

issue

11

eissn

0003-9888

issn

1468-2044

journal_volume

63

pub_type

杂志文章
  • Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery.

    abstract:BACKGROUND AND AIMS:The case fatality rate from meningococcal disease (MD) has remained relatively unchanged in the post antibiotic era, with 20-50% of patients who develop shock still dying. In 1992 a new paediatric intensive care unit (PICU) specialising in MD was opened. Educational information was disseminated to l...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.85.5.386

    authors: Booy R,Habibi P,Nadel S,de Munter C,Britto J,Morrison A,Levin M,Meningococcal Research Group.

    更新日期:2001-11-01 00:00:00

  • Clostridium difficile after haemolytic uraemic syndrome.

    abstract::Six children are described who developed diarrhoea associated with Clostridium difficile during the course of haemolytic uraemic syndrome. The significance of this infection is discussed within the context of the pathophysiology of haemolytic uraemic syndrome. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.69.2.239

    authors: Burgner DP,Rfidah H,Beattie TJ,Seal DV

    更新日期:1993-08-01 00:00:00

  • Association between urinary symptoms at 7 years old and previous urinary tract infection.

    abstract::The association between current micturition habits and previous urinary tract infection was analysed among 3553 school entrants aged 7 years by means of a questionnaire. A high incidence of urinary infection, confirmed by urine culture, was found (145 (8.4%) in the 1719 girls and 32 (1.7%) in the 1834 boys). There was...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.2.232

    authors: Hellström A,Hanson E,Hansson S,Hjälmås K,Jodal U

    更新日期:1991-02-01 00:00:00

  • Fructose breath hydrogen tests.

    abstract::Fructose absorption was studied by the breath hydrogen test in 114 healthy children aged 0.1-6 years, given either 2 g/kg or 1 g/kg of fructose. All 57 children given 2 g/kg had peak breath hydrogen excretions > or = 20 ppm. At 1 g/kg only 25/57 (44%) showed incomplete absorption and the percentage incompletely absorb...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.68.1.136

    authors: Hoekstra JH,van Kempen AA,Bijl SB,Kneepkens CM

    更新日期:1993-01-01 00:00:00

  • Long term follow up after inhalation of foreign bodies.

    abstract::The long term results of treatment of inhalation of foreign bodies in a district children's hospital and in a tertiary referral centre were reviewed by clinical assessment, chest radiography, and standard four view 81mKr ventilation/99mTc macroaggregated albumin perfusion imaging (V/Q lung scan). The overall incidence...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.65.6.619

    authors: Davies H,Gordon I,Matthew DJ,Helms P,Kenney IJ,Lutkin JE,Lenney W

    更新日期:1990-06-01 00:00:00

  • Two hundred glass injuries.

    abstract::Two hundred children with glass injuries were investigated; 48 were injured in falls through architectural glass and 87 by broken bottles. Nine children had serious lacerations--7 of which were sustained at home. Radiographs were important in diagnosing retained fragments but prophylactic antibiotics were unnecessary....

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.59.7.672

    authors: Bell D

    更新日期:1984-07-01 00:00:00

  • Abnormal serum IgG subclass pattern in children with Down's syndrome.

    abstract::Susceptibility to infections is a well known feature of Down's syndrome. The possible relation between this predisposition and the serum concentrations of the IgG subclasses was studied in 38 children with Down's syndrome aged 1-12 years. An age matched group of 50 healthy children served as controls. The serum concen...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.5.628

    authors: Annerén G,Magnusson CG,Lilja G,Nordvall SL

    更新日期:1992-05-01 00:00:00

  • Health consequences of obesity.

    abstract::The recent epidemic of childhood obesity(1) has raised concern because of the possible clinical and public health consequences.(2,)(3) However, there remains a widespread perception among health professionals that childhood obesity is a largely cosmetic problem, with minor clinical effects. No systematic review has ye...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,meta分析,评审

    doi:10.1136/adc.88.9.748

    authors: Reilly JJ,Methven E,McDowell ZC,Hacking B,Alexander D,Stewart L,Kelnar CJ

    更新日期:2003-09-01 00:00:00

  • Symptoms of bronchial hyperreactivity and asthma in relation to environmental factors.

    abstract::A questionnaire study regarding airway morbidity in children and environmental factors was performed in April 1985. The parents of 5301 children, aged 6 months to 16 years, from different rural areas in mid Sweden were sent a validated questionnaire and 4990 (94%) responded. The cumulative prevalence of bronchial hype...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.63.5.473

    authors: Andrae S,Axelson O,Björkstén B,Fredriksson M,Kjellman NI

    更新日期:1988-05-01 00:00:00

  • Psychogenic non-epileptic seizures: management and prognosis.

    abstract:AIM:To determine the outcome and identify predictive factors in children with psychogenic non-epileptic seizures (PNES). METHOD:The biographies of 35 children with PNES, attending a tertiary paediatric neurology centre, were reviewed. RESULTS:Thirty five children attending the department between 1987 and 1997 were ev...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.82.6.474

    authors: Irwin K,Edwards M,Robinson R

    更新日期:2000-06-01 00:00:00

  • Hepatopathy of Mauriac syndrome: a retrospective review from a tertiary liver centre.

    abstract:BACKGROUND:Mauriac syndrome is characterised by growth failure, cushingoid appearance and hepatomegaly which occurs in patients with insulin dependent diabetes and was first described shortly after the introduction of insulin as a treatment for the condition. OBJECTIVE:To describe the clinical features, histological f...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2013-304426

    authors: Fitzpatrick E,Cotoi C,Quaglia A,Sakellariou S,Ford-Adams ME,Hadzic N

    更新日期:2014-04-01 00:00:00

  • Calcium, magnesium, and glucose levels in blood and CSF of children with febrile convulsions.

    abstract::Levels of calcium, magnesium, and glucose were measured in the blood and cerebrospinal fluid (CSF) of children with febrile convulsions. Calcium and magnesium levels were within the normal range and the blood: CSF ratios were similar to those of normal subjects. Hyperglycaemia was a frequent finding and was reflected ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.51.2.141

    authors: Rutter N,Smales OR

    更新日期:1976-02-01 00:00:00

  • Treatment of pseudomonas aeruginosa colonisation in cystic fibrosis.

    abstract::To test whether early treatment could postpone the chronic colonisation of the respiratory tract with mucoid strains of Pseudomonas aeruginosa in patients with cystic fibrosis, we performed a pilot study in 28 patients aged 2 to 18 years. A two week course of azlocillin (150 mg/kg/day) and tobramycin (10 to 15 mg/kg/d...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.64.7.1022

    authors: Steinkamp G,Tümmler B,Malottke R,von der Hardt H

    更新日期:1989-07-01 00:00:00

  • Parents measuring pulses; an observational study.

    abstract::Parent reported pulse rates could provide important information on a child's clinical condition. The agreement between the parent's measurement of their child's pulse and a pulse oximeter was assessed following a brief educational intervention. Parents can be taught to measure the pulse of school age children, but hav...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2002.025643

    authors: White J,Shepperd S,Yudkin P,Harnden A,Mant D

    更新日期:2004-03-01 00:00:00

  • Megarectum in constipation.

    abstract:BACKGROUND:Faecal impaction is frequently observed in children with chronic constipation. The term megarectum is often used to describe this finding. AIM:To evaluate rectal functioning and rectal measures in constipated children with a filled rectum, in order to define the terms faecal impaction, enlarged rectum, and ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.83.1.52

    authors: van der Plas RN,Benninga MA,Staalman CR,Akkermans LM,Redekop WK,Taminiau JA,Buller HA

    更新日期:2000-07-01 00:00:00

  • Assuring validity of multisource feedback in a national programme.

    abstract:OBJECTIVE:To report the evidence for and challenges to the validity of Sheffield Peer Review Assessment Tool (SPRAT) with paediatric Specialist Registrars (SpRs) across the UK as part of Royal College of Paediatrics and Child Health workplace based assessment programme. DESIGN:Quality assurance analysis, including gen...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/adc.2008.146209

    authors: Archer J,McGraw M,Davies H

    更新日期:2010-05-01 00:00:00

  • Family resemblances of height, weight, and body fatness.

    abstract::In a study of 256 families, among whom were twins, midparent-adult son correlations for height, weight, and combined skinfold measurements were 0.67, 0.47, and 0.23 respectively. The corresponding midparent-adult daughter correlations were 0.63, 0.42, and 0.24. Midparent-growing offspring correlations were highest for...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.54.11.877

    authors: Hawk LJ,Brook CG

    更新日期:1979-11-01 00:00:00

  • Recovery of protein from urine specimens collected in cotton wool.

    abstract::Cotton wool balls have been used to aid the collection of urine from infants. Concentrations of two urinary proteins, albumin and retinol binding protein, decreased by 40 and 80% respectively within 15 minutes of contact with the cotton wool. Cotton wool balls should not be used when investigating proteinuria. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.12.1486

    authors: Smith GC,Taylor CM

    更新日期:1992-12-01 00:00:00

  • Age dependence of flow velocities in basal cerebral arteries.

    abstract::Flow velocities in the basal cerebral arteries were studied by transcranial Doppler sonography. A longitudinal study was undertaken on 25 healthy newborn babies during the first 20 days of life, and a cross sectional study was performed on 112 healthy children between 1 day and 18 years of age. A rapid linear increase...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.63.6.606

    authors: Bode H,Wais U

    更新日期:1988-06-01 00:00:00

  • Clinical significance of cough and wheeze in the diagnosis of asthma.

    abstract:OBJECTIVES:(1) To determine the prevalence of cough, wheeze, and breathlessness, both as single symptoms and in combination, in primary schoolchildren and their relation to doctor diagnosed asthma. (2) To identify in areas with different levels of dust pollution whether questionnaire reported 'cough alone' (without whe...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.75.6.489

    authors: Kelly YJ,Brabin BJ,Milligan PJ,Reid JA,Heaf D,Pearson MG

    更新日期:1996-12-01 00:00:00

  • Value of cystography in urinary tract infections.

    abstract::Fifty-one children with a bacteriologically proven urinary tract infection had both an intravenous urogram (IVU) and a micturating cystogram. The IVU was normal in 35. Only 6 of these children showed reflux in the cystogram, affecting 7 of the 70 ureters at risk. Since reflux on its own does not cause renal damage, wh...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.51.11.893

    authors: Moncrieff MW,Whitelaw R

    更新日期:1976-11-01 00:00:00

  • Characteristics of disorders associated with genetic mutations of surfactant protein C.

    abstract:STUDY OBJECTIVES:To present diagnosis and treatment modalities of children with interstitial lung disease associated with frequent or rare surfactant protein C gene (SFTPC) mutation. PATIENTS:Twenty-two children with chronic lung disease associated with SFTPC mutation in a heterozygous form. RESULTS:Mutations located...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/adc.2009.171553

    authors: Thouvenin G,Abou Taam R,Flamein F,Guillot L,Le Bourgeois M,Reix P,Fayon M,Counil F,Depontbriand U,Feldmann D,Pointe HD,de Blic J,Clement A,Epaud R

    更新日期:2010-06-01 00:00:00

  • Cardiovascular abnormalities in end stage renal failure: the effect of anaemia or uraemia?

    abstract::Children with end stage renal failure and anaemia have an increased cardiac index and often gross ventricular hypertrophy. Correction of anaemia with recombinant human erythropoietin (r-HuEpo) for less than six months results in a reduction in the cardiac index without a significant reduction in left ventricular hyper...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.71.2.119

    authors: Morris KP,Skinner JR,Hunter S,Coulthard MG

    更新日期:1994-08-01 00:00:00

  • Neonatal urological ultrasound: diagnostic inaccuracies and pitfalls.

    abstract::Ninety one patients with urinary tract abnormalities diagnosed before birth were reviewed. Diagnoses based on prenatal and postnatal ultrasound scans alone were compared with the final diagnoses after full urological investigations, with operative or necropsy confirmation in 79 cases. The results confirmed that ultras...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.64.4.578

    authors: Clarke NW,Gough DC,Cohen SJ

    更新日期:1989-04-01 00:00:00

  • Drug utilisation among Dutch adolescents: a pharmacy prescription records study.

    abstract:BACKGROUND:Studies on adolescent drug use are scarce as most studies do not distinguish between children and adolescents. Therefore, we assessed overall drug use in adolescents. METHODS:A retrospective cohort study was conducted using pharmacy dispensing records from 62 community pharmacies in the Netherlands. Dispens...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2017-314692

    authors: Kosse RC,Koster ES,de Vries TW,Bouvy ML

    更新日期:2019-08-01 00:00:00

  • Auditing hip ultrasound screening of infants at increased risk of developmental dysplasia of the hip.

    abstract:BACKGROUND:Clinical examination, while useful, has been shown to be insufficient as the sole screening method in infants. Ultrasound examination at 8 weeks in high risk infants is an integral part of the screening process in some units. AIMS:To show the efficiency of hip sonography in detection of developmental dyspla...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2003.033597

    authors: Lowry CA,Donoghue VB,Murphy JF

    更新日期:2005-06-01 00:00:00

  • Pyrexia after diphtheria/tetanus/pertussis and diphtheria/tetanus vaccines.

    abstract::The temperatures of 587 children were taken before and after diphtheria/tetanus/pertussis (DTP) or diphtheria/tetanus (DT) vaccine. Only slight temperature increases were found but these were notably more frequent after plain than adsorbed DTP vaccine preparations and the frequency increased with each successive dose....

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.58.11.921

    authors: Waight PA,Pollock TM,Miller E,Coleman EM

    更新日期:1983-11-01 00:00:00

  • Asthma drug adherence in a long term clinical trial.

    abstract:AIM:To measure drug adherence in children with mild asthma receiving long term prophylactic treatment. METHODS:Double blind randomised placebo controlled trial. Patients received inhaled budesonide 100 microg or 200 microg daily, or placebo for 27 months. All participants were asked to inhale medication or placebo fro...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/adc.83.4.330

    authors: Jónasson G,Carlsen KH,Mowinckel P

    更新日期:2000-10-01 00:00:00

  • When should oxygen be given to children at high altitude? A systematic review to define altitude-specific hypoxaemia.

    abstract:BACKGROUND:Acute respiratory infections (ARI) cause 3 million deaths in children worldwide each year. Most of these deaths occur from pneumonia in developing countries, and hypoxaemia is the most common fatal complication. Simple and adaptable indications for oxygen therapy are important in the management of ARI. The c...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2008.138362

    authors: Subhi R,Smith K,Duke T

    更新日期:2009-01-01 00:00:00

  • Epidemiology of pyridoxine dependent and pyridoxine responsive seizures in the UK.

    abstract:OBJECTIVE:To study the epidemiology of pyridoxine dependent seizures and other forms of pyridoxine responsive seizures. DESIGN:Monthly notifications to the British Paediatric Surveillance Unit over two years. Questionnaire follow up. SETTING:UK and the Republic of Ireland. PATIENTS:Children aged 15 years or younger ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.81.5.431

    authors: Baxter P

    更新日期:1999-11-01 00:00:00