Abnormal serum IgG subclass pattern in children with Down's syndrome.

abstract：:Acute viral respiratory illness during infancy has been implicated as a precursor for subsequent lower respiratory morbidity in childhood. A prospective, longitudinal study of respiratory function, airway responsiveness, and lower respiratory illness during early childhood was performed in a cohort of 253 healthy infa...

journal_title：Archives of disease in childhood

authors： Young S,O'Keeffe PT,Arnott J,Landau LI

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:To examine the role of viruses in febrile seizures (FS) by comparing the relative risk (RR) of developing FS with common viral infections and subsequent risk of recurrence. METHODS:We matched the medical records of all children admitted with FS over 5 years and the contemporary records for all admissions fo...

journal_title：Archives of disease in childhood

authors： Chung B,Wong V

更新日期：2007-07-01 00:00:00

abstract：:In 1973 a survey was conducted among 12 year old children living in a defined area of South Wales. In 1988 the survey was repeated in the same area, again among 12 year old children. Questionnaires were completed for all 965 children in the population sample; peak expiratory flow rates were performed on them all, and ...

journal_title：Archives of disease in childhood

authors： Burr ML,Butland BK,King S,Vaughan-Williams E

更新日期：1989-10-01 00:00:00

abstract：:Twenty six children with hypoglycaemia were diagnosed and followed between 1975 and 1995. Diagnosis was confirmed by a high insulin:glucose ratio, and low free fatty acid and 3-hydroxybutyrate on fasting. All patients were treated with diazoxide at a maximum dose of 20 mg/kg/day. Requirement of a higher dose was consi...

journal_title：Archives of disease in childhood

authors： Cresto JC,Abdenur JP,Bergada I,Martino R

更新日期：1998-11-01 00:00:00

abstract：:We investigated the associations between albuminuria, metabolic control, glomerular filtration, blood pressure, and platelet function in children with insulin dependent diabetes mellitus. The geometric mean (95% tolerance levels) albumin excretion (expressed as the geometric mean albumin to creatinine ratio on two ove...

journal_title：Archives of disease in childhood

authors： Gibb DM,Dunger D,Levin M,Shah V,Smith C,Barratt TM

更新日期：1989-07-01 00:00:00

abstract：:Thirty jaundiced neonates with diarrhoea who were being treated with phototherapy and 30 matched control infants were studied to try and find out the cause of the diarrhoea. Faecal osmolality and electrolyte concentrations were measured, which gave clear evidence that the diarrhoea arose from intestinal secretion. Rec...

journal_title：Archives of disease in childhood

authors： De Curtis M,Guandalini S,Fasano A,Saitta F,Ciccimarra F

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:The development, delivery and evaluation of a training programme for medical and nursing professionals on best practice for informing families of their child's disability. DESIGN:A 2 h training course on 'Best practice guidelines for informing families of their child's disability' was designed based on the f...

journal_title：Archives of disease in childhood

authors： Harnett A,Bettendorf E,Tierney E,Guerin S,O'Rourke M,Hourihane JO

更新日期：2013-06-01 00:00:00

abstract：:The National Health Service, in its report An organisation with memory, has called for a fundamental rethinking of the way the healthcare system learns from error. The NHS further details its goal to reduce serious medication errors by 40% in a second report entitled Building a safer NHS: improving medication safety. ...

journal_title：Archives of disease in childhood

authors： Walsh KE,Kaushal R,Chessare JB

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND AIMS:There are few standardised questionnaires for the assessment of respiratory symptoms in preschool children. We have developed and tested the short-term repeatability of a postal questionnaire on respiratory symptoms for 1-year-old children. METHODS:A newly developed postal questionnaire for the ass...

journal_title：Archives of disease in childhood

authors： Strippoli MP,Silverman M,Michel G,Kuehni CE

更新日期：2007-10-01 00:00:00

abstract：:Three cases are reported in which thrombi were found in the aorta at postmortem. In each case the thrombus had originated within the ductus arteriosus. We believe that in recent years the attention paid to the presence of indwelling cannulae as a cause of embolic phenomena in the newborn period has led to a reduction ...

journal_title：Archives of disease in childhood

authors： Knowlson GT,Marsden HB

更新日期：1978-02-01 00:00:00

abstract：:Ten patients with biotinidase deficiency were studied. Clinical findings at presentation varied with dermatological signs (dermatitis and alopecia), neurological abnormalities (fits, hypotonia, and ataxia), and recurrent infections being the most common features, although none of these occurred in every case. Biochemi...

journal_title：Archives of disease in childhood

authors： Wastell HJ,Bartlett K,Dale G,Shein A

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Respiratory viral infections precipitate exacerbations of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease though similar data in non-cystic fibrosis (CF) bronchiectasis are missing. Our study aimed to determine the point prevalence of viruses associated with exacerbation...

journal_title：Archives of disease in childhood

authors： Kapur N,Mackay IM,Sloots TP,Masters IB,Chang AB

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Previous research has indicated that children who have received treatment for leukaemia which includes cranial irradiation exhibit deficits in their ability to focus attention. It has been suggested that the use of cranial irradiation may have a role to play in long term sequelae. AIMS:To investigate neurop...

journal_title：Archives of disease in childhood

authors： Rodgers J,Marckus R,Kearns P,Windebank K

更新日期：2003-02-01 00:00:00

abstract：:In this review, we survey some significant advances in the medical care of babies <1000 g and we highlight the development of care pathways that ensure optimal antenatal care, which is a prerequisite for good neonatal outcomes. We also suggest that the long overdue development of family integrated care will in the end...

journal_title：Archives of disease in childhood

authors： Berrington J,Ward Platt M

更新日期：2016-11-01 00:00:00

abstract：:Sympathetic function was studied in 101 diabetic children and 102 age and sex matched control children, as part of a longitudinal study of the evolution of microvascular disease in the population of diabetic children and adolescents in Avon County. The median (range) age of the diabetic population was 13.5 (6.0-17.2) ...

journal_title：Archives of disease in childhood

authors： Karavanaki K,Davies AG,Hunt LP,Morgan MH,Baum JD

更新日期：1994-12-01 00:00:00

abstract：:162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused pronounced side effects, and the mortality was 4.9%. The most common complications were infections: sep...

journal_title：Archives of disease in childhood

authors： Riikonen R,Donner M

更新日期：1980-09-01 00:00:00

abstract：:The performance of indirect indices of infection in the newborn vary because of differences in techniques, including diagnostic cut off levels. We have compared serial neutrophil band cell counts with C reactive protein measured by rate nephelometry. The 'gold standard' was a positive culture and the performance of th...

journal_title：Archives of disease in childhood

authors： Russell GA,Smyth A,Cooke RW

更新日期：1992-07-01 00:00:00

abstract：:Growth was studied in 83 children with cleft lip and/or palate aged 0-4 years attending a specialist regional centre. Information was collected by a personal interview, postal questionnaire, and record review. The group as a whole grew relatively poorly in early infancy but subsequently recovered, attaining both expec...

journal_title：Archives of disease in childhood

authors： Lee J,Nunn J,Wright C

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To develop and test patient-reported experience measures (PREMs) for children and young people in a specialist paediatric hospital setting. DESIGN:Six PREMs were developed and tested by children and young people for children and young people aged 8-11, 12-13 and 14-16 years in inpatient and outpatient settin...

journal_title：Archives of disease in childhood

authors： Wray J,Hobden S,Knibbs S,Oldham G

更新日期：2018-03-01 00:00:00

abstract：:The metabolism and excretion of paracetamol was studied in an infant of 29 weeks' gestation who was exposed to the drug when his mother ingested 32.5 g 16 hours before delivery. We have confirmed that sulphation is the major pathway and that the mixed function oxidase system is sufficiently active at this gestational ...

journal_title：Archives of disease in childhood

authors： Lederman S,Fysh WJ,Tredger M,Gamsu HR

更新日期：1983-08-01 00:00:00

abstract：:A children's hospital nutritional care team prospectively monitored the frequency of sepsis in central venous catheters used for administering parenteral nutrition. During an initial study period of 12 months, 26/58 (45%) of catheters were removed because of proved sepsis. The possible causes of this alarmingly high r...

journal_title：Archives of disease in childhood

authors： Puntis JW,Holden CE,Smallman S,Finkel Y,George RH,Booth IW

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:There are few data on the optimal micronutrient composition of paediatric enteral feeds. The recent European Directive on Foods for Special Medical Purposes (1999/21/EC) did not distinguish between the composition of adult and paediatric feeds. AIMS:To evaluate, in an open, observational study, the long ter...

journal_title：Archives of disease in childhood

authors： Johnson TE,Janes SJ,MacDonald A,Elia M,Booth IW

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The evidence base to guide the pharmacological management of tone and abnormal movements in cerebral palsy (CP) is limited, as is an understanding of routine clinical practice in the UK. We aimed to establish details of motor phenotype and current pharmacological management of a representative cohort across ...

journal_title：Archives of disease in childhood

authors： Lumsden DE,Crowe B,Basu A,Amin S,Devlin A,DeAlwis Y,Kumar R,Lodh R,Lundy CT,Mordekar SR,Smith M,Cadwgan J

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To develop a clinical algorithm to identify paediatric patients who should be offered HIV testing in a setting of moderate HIV prevalence and limited resources. METHODS:In a prospective cross-sectional study at Port Moresby General Hospital, Papua New Guinea, carers of inpatients were offered HIV testing and...

journal_title：Archives of disease in childhood

authors： Allison WE,Kiromat M,Vince J,Wand H,Cunningham P,Graham SM,Kaldor J

更新日期：2011-01-01 00:00:00

abstract：:Blood lead concentrations and body iron status were investigated in 279 children. Blood lead concentrations showed no increase during iron depletion phase (stage I) but markedly increased from the phase of iron deficient erythropoiesis (stage II). Increased blood lead concentrations in anaemic subjects significantly d...

journal_title：Archives of disease in childhood

authors： Choi JW,Kim SK

更新日期：2003-09-01 00:00:00

abstract：:We describe two cases of a non-epileptic florid movement disorder presenting as status epilepticus. Both patients presented with florid jerking of the limbs and eyes. Convulsive status epilepticus related to presumed meningitis or encephalitis was suspected in both cases. The patients received treatment for seizures, ...

journal_title：Archives of disease in childhood

authors： Haden SV,McShane MA,Holt CM

更新日期：2009-11-01 00:00:00

abstract：:Premature newborn rabbits, delivered on day 27 of gestation, were treated with tracheal deposition of dry artificial surfactant containing dipalmitoyl phosphatidylcholine and unsaturated phosphatidylglycerol (7:3), or crude natural surfactant prepared by centrifugation of lung wash from adult rabbits. Before receiving...

journal_title：Archives of disease in childhood

authors： Morley C,Robertson B,Lachmann B,Nilsson R,Bangham A,Grossmann G,Miller N

更新日期：1980-10-01 00:00:00

abstract：:To test whether early treatment could postpone the chronic colonisation of the respiratory tract with mucoid strains of Pseudomonas aeruginosa in patients with cystic fibrosis, we performed a pilot study in 28 patients aged 2 to 18 years. A two week course of azlocillin (150 mg/kg/day) and tobramycin (10 to 15 mg/kg/d...

journal_title：Archives of disease in childhood

authors： Steinkamp G,Tümmler B,Malottke R,von der Hardt H

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To explore the effect of research ethics, governance and consent requirements and recent reforms on UK-wide follow-up of children with congenital heart defects (CHD). DESIGN:Prospective cohort study. SETTING:UK National Health Service. PATIENTS:3897 children with CHD requiring intervention, or resulting in...

journal_title：Archives of disease in childhood

authors： Knowles RL,Bull C,Wren C,Dezateux C

更新日期：2011-01-01 00:00:00

abstract：:Endogenous formation of thromboxane A2 and prostacyclin were evaluated in seven neonatates with persistent pulmonary hypertension by serial gas chromatographic mass spectrometric determination of their urinary metabolites dinor-thromboxane B2 and dinor-6-keto-prostaglandin F1 alpha, respectively. The patients were stu...

journal_title：Archives of disease in childhood

authors： Kühl PG,Cotton RB,Schweer H,Seyberth HW

更新日期：1989-07-01 00:00:00