Abstract:
OBJECTIVES:To examine the role of viruses in febrile seizures (FS) by comparing the relative risk (RR) of developing FS with common viral infections and subsequent risk of recurrence. METHODS:We matched the medical records of all children admitted with FS over 5 years and the contemporary records for all admissions for febrile illnesses associated with influenza, adenovirus, parainfluenza, respiratory syncytial virus (RSV) and rotavirus to calculate the RR of FS following these viral infections. For patients admitted for a first FS, we carried multivariate analysis for type of viral infection, age of onset, family history, complex FS features and maximum temperature during the episode, to identify the risk factors for recurrence. RESULTS:There were 923 admissions for FS, of which 565 were for first seizures. The five most common viruses in FS were influenza (163/923, 17.6%), adenovirus (63/923, 6.8%), parainfluenza (55/923, 6%), RSV (25/923, 2.7%) and rotavirus (12/923, 1.3%). Incidences of FS in febrile illnesses due to these viruses were 20.8% (163/785) for influenza, 20.6% (55/267) for parainfluenza, 18.4% (63/343) for adenovirus, 5.3% (25/468) for RSV and 4.3% (12/280) for rotavirus. Complex FS occurred in 20.6% (n = 191) and the risk of developing complex FS was similar for the five viruses. Overall recurrence rate was 20.5% and was not predicted by type of viral infection. CONCLUSION:The risk of developing FS is similar with influenza, adenovirus or parainfluenza and is higher than with RSV or rotavirus. Type of viral infection is not important in predicting complex features or future recurrences.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Chung B,Wong Vdoi
10.1136/adc.2006.110221subject
Has Abstractpub_date
2007-07-01 00:00:00pages
589-93issue
7eissn
0003-9888issn
1468-2044pii
adc.2006.110221journal_volume
92pub_type
杂志文章abstract:PURPOSE:To prospectively examine relations between maternal DSM-IV-TR anxiety and depressive disorders and excessive infant crying. METHODS:Based on the prospective longitudinal Maternal Anxiety in Relation to Infant Development Study, n=306 expectant mothers were enrolled during early pregnancy and repeatedly intervi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2013-305562
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:The atherogenic risk factor profile in obese subjects is characterised by hypertension, reduced high density lipoprotein (HDL) cholesterol, increased low density lipoprotein (LDL) cholesterol and triglycerides, and insulin resistance. AIMS:To examine the amount of weight reduction required to improve the at...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2003.028803
更新日期:2004-05-01 00:00:00
abstract::A 9 year old boy with intractable postprandial reflex vomiting was taught a self hypnotherapy technique incorporating relaxation exercises, mental imagery, and suggestions of symptom relief. The sequence was recorded on a personal stereo cassette tape. Vomiting was completely eliminated within four weeks. At 12 month ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.6.626
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVES:(1) To determine the prevalence of cough, wheeze, and breathlessness, both as single symptoms and in combination, in primary schoolchildren and their relation to doctor diagnosed asthma. (2) To identify in areas with different levels of dust pollution whether questionnaire reported 'cough alone' (without whe...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.6.489
更新日期:1996-12-01 00:00:00
abstract:AIM:Assessment of the efficacy of vitamin D replenishment and maintenance doses required to attain optimal levels in boys with Duchenne muscular dystrophy (DMD). METHOD:25(OH)-vitamin D levels and concurrent vitamin D dosage were collected from retrospective case-note review of boys with DMD at the Dubowitz Neuromuscu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2015-308825
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To describe the recent trends in demographic, clinical and microbiological characteristics and outcome of treatment in paediatric cases of tuberculosis. DESIGN:National surveillance study. SETTING:England and Wales. PATIENTS:All children under the age of 16 years reported with tuberculosis to the national ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2008.139543
更新日期:2008-12-01 00:00:00
abstract::Reflection has become established as a key principle underpinning maintenance of standards within professional education and practice. A requirement to evidence reflection within performance review is intended to develop a transformative approach to practice, identify developmental goals, and ultimately, improve healt...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2013-303948
更新日期:2014-03-01 00:00:00
abstract::Malaria, as a key disease of poverty, was singled out for special attention in the Millennium Project of 2000. Recent data suggest that malaria incidence and mortality are now declining all over the world. While these figures are cause for celebration, they must be interpreted carefully and with caution, particularly ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2013-305441
更新日期:2015-02-01 00:00:00
abstract::Adrenal cortical carcinoma in a 4 1/4-month-old girl was treated by surgery in combination with actinomycin D, cyclophosphamide, and 5-fluorouracil given daily for 5 days every third week for 13 1/2 months. Postoperative hypertension and raised 24-hour 17-hydroxy- and 21-oxosteroids suggested residual microscopical tu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.53.4.342
更新日期:1978-04-01 00:00:00
abstract::The effect of phototherapy on plasma cyclic-AMP in newborn infants has been studied. Our results suggest that phototherapy does not produce appreciable changes in plasma cyclic-AMP levels. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.5.416
更新日期:1977-05-01 00:00:00
abstract::Twenty children (age range 75 days-47 months) with reflux oesophagitis entered a random double blind trial in which they received either Cisapride (Janssen Pharmaceutical Ltd), a new prokinetic agent, or an identical placebo syrup. Diagnosis of gastro-oesophageal reflux was made by measurement of intraluminal oesophag...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.62.5.454
更新日期:1987-05-01 00:00:00
abstract::Anomalies of the bronchial cilia were studied in 5 children with recurrent pulmonary infections. Case 1 had Kartagener's syndrome and an absence of the inner and outer dynein arms in most cilia, although a few shortened and even some normal arms could be seen. Cases 2 and 3 had unilateral bronchiectasis without family...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.56.12.929
更新日期:1981-12-01 00:00:00
abstract::Seven children with precocious puberty were treated with cyproterone acetate and their adrenal function studied. In each child the drug caused significant adrenal hypofunction which was secondary to adrenocorticotrophic hormone suppression. None of these children had clinical evidence of adrenal hypofunction and it is...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.56.3.218
更新日期:1981-03-01 00:00:00
abstract::Serial small intestinal biopsies related to withdrawal and challenge with cows' milk are described in 5 infants with cows' milk protein intolerenace. On the basis of these serial observations the existence of a cows' milk-sensitive enteropathy in infancy is clearly established. The cows' milk-sensitive mucosal lesion ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.53.5.375
更新日期:1978-05-01 00:00:00
abstract:AIM:To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1-16 years. METHODS:A national prospective population-based cohort study over 25 months. Newly diagnosed PTCS cases notified via British Paediatric Surveillance Unit were ascertained using cla...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2016-312238
更新日期:2017-08-01 00:00:00
abstract::The relation between intraventricular haemorrhage (IVH) and hyaline membrane disease (HMD) was studied in singletons that came to necropsy at Hammersmith Hospital over the years 1966-73. The incidence of IVH in singleton live births was 3-22/1000 and of HMD 4-44/1000. Although the high figures were partily due to the ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.10.755
更新日期:1976-10-01 00:00:00
abstract::Eight patients with the middle aortic syndrome are described. They were aged 2 months to 14 years at diagnosis; follow up was one to 11 years. Clinical presentations included asymptomatic hypertension (n = 5), severe headache, nose bleed, and chest pain (n = 1), and cardiac failure (n = 1). All had severe hypertension...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.67.4.501
更新日期:1992-04-01 00:00:00
abstract::Up to date reference ranges were established for fasting renal excretion of calcium, phosphorus, and magnesium on 101 healthy children aged 2-15 years. A normal range for intact parathyroid hormone was also measured. The indices of calcium and magnesium excretion showed no correlation with age or sex so that a common ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.11.1208
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND:Human metapneumovirus (hMPV) causes lower respiratory tract infections, particularly in young children and the elderly. METHODS:A prospective study was conducted on the clinical characteristics of infants <2 years of age admitted to hospital for respiratory infection and the characteristics of hMPV infectio...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2005.082388
更新日期:2006-04-01 00:00:00
abstract::Fructose absorption was studied by the breath hydrogen test in 114 healthy children aged 0.1-6 years, given either 2 g/kg or 1 g/kg of fructose. All 57 children given 2 g/kg had peak breath hydrogen excretions > or = 20 ppm. At 1 g/kg only 25/57 (44%) showed incomplete absorption and the percentage incompletely absorb...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.1.136
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Vanessa is a 34-year-old lawyer married to a police officer. Her first baby was born after a perfect pregnancy and labour until fetal distress necessitated an easy Ventouse extraction late in the second stage. Baby F had normal Apgar scores and weighed 2920 g. This paper records a conversation between Vaness...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2006.101600
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To study the relation between traumatic birth and the development of permanent facial palsy in the newborn. DESIGN:Retrospective case control study of children with 'congenital' facial palsy. SETTING:Two tertiary referral centres for patients with facial palsy. SUBJECTS:61 children with established facial ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.74.1.56
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:National and international recommendations for the age of introducing solid foods (weaning) are founded on insufficient evidence and little is known about the short and medium term consequences associated with early or late weaning. AIMS AND METHODS:Data from over 1600 infants from five prospective randomis...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,meta分析,随机对照试验
doi:10.1136/adc.2003.036137
更新日期:2004-08-01 00:00:00
abstract::Two cross sectional surveys, 24 years apart, using the same respiratory questionnaire, were carried out to examine changes in prevalence rates of cough, phlegm, and wheeze and to relate changes in wheeze to objective peak expiratory flow rates (PEFRs). The surveys were done in towns in southern and northern England an...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.6.729
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND:Studies on adolescent drug use are scarce as most studies do not distinguish between children and adolescents. Therefore, we assessed overall drug use in adolescents. METHODS:A retrospective cohort study was conducted using pharmacy dispensing records from 62 community pharmacies in the Netherlands. Dispens...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2017-314692
更新日期:2019-08-01 00:00:00
abstract::There may be insufficient awareness of dopa responsive dystonia (DRD), which has a characteristic diurnal variation of symptoms. Two children are reported in whom the diagnosis of DRD was missed. The first was thought to have hysteria and the second hereditary spastic paraparesis. A full history is vital for the diagn...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.73.3.256
更新日期:1995-09-01 00:00:00
abstract:INTRODUCTION:Intravenous paracetamol (acetaminophen) has recently been registered for treatment of pain in neonates but the pharmacodynamics, including effects on body temperature, have not been reported. METHODS:A pooled analysis on body temperature recordings in neonates exposed to intravenous paracetamol was perfor...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2010.203778
更新日期:2011-03-01 00:00:00
abstract::Thirty six children with typical features of Angelman's syndrome, including global developmental delay, ataxia, episodes of paroxysmal laughter, seizures, and microcephaly were studied. The series included three sibships of three affected sisters, two affected brothers, and two affected sisters, respectively. The faci...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.64.1.83
更新日期:1989-01-01 00:00:00
abstract::We describe a non-progressive choreo-athetoid disorder of early onset, present in three families. There were no appreciable abnormalities in pregnancy, during the perinatal period, or in infancy. In each case the family history suggested transmission as an autosomal dominant trait, the gene showing diminished penetran...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.56.8.616
更新日期:1981-08-01 00:00:00
abstract::The improvement in audiological testing of children post-meningitis with one retrospective and two prospective audit cycles, is described. Direct referral by telephone prior to discharge and liaison with public health colleagues resulted in an increased assessment from 50% to 99% and 89% in successive audits. The prop...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.11.976
更新日期:2003-11-01 00:00:00