当前位置： SCI文献检索 > DEVELOPMENTAL BIOLOGY期刊下所有文献 > Urodeles remove mesoderm from the superficial layer by subduction through a bilateral primitive streak.

Urodeles remove mesoderm from the superficial layer by subduction through a bilateral primitive streak.

Abstract：

:Urodeles begin gastrulation with much of their presumptive mesoderm in the superficial cell layer, all of which must move into the deep layers during development. We studied the morphogenesis of superficial mesoderm in the urodeles Ambystoma maculatum, Ambystoma mexicanum, and Taricha granulosa. In all three species, somitic, lateral, and ventral mesoderm move into the deep layer during gastrulation, ingressing through a "bilateral primitive streak" just inside the blastopore. The mesodermal epithelium appears to slide under the endodermal epithelium by a mechanism we term "subduction." Subduction removes the large expanse of superficial presumptive somitic and lateral-ventral mesoderm that initially separates the sub-blastoporal endoderm from the notochord, leaving the endoderm bounding the still epithelial notochord along the gastrocoel roof. Subduction may be a common feature of urodele gastrulation, differing in this regard from anurans. Subducting cells constrict their apices and become bottle-shaped as they approach the junction of the mesodermal and endodermal epithelia. Subducting bottle cells endocytose apical membrane and withdraw the tight junctional component cingulin from the contracting circumferential tight junctions. Either in conjunction with or immediately after subducting, the mesodermal cells undergo an epithelial-to-mesenchymal transition. The mechanism by which epithelial cells release their apical junctions to become mesenchymal, without disrupting the integrity of the epithelium, remains mysterious, but this system should prove useful in understanding this process in a developmental context.

journal_name

Dev Biol

journal_title

Developmental biology

authors

Shook DR,Majer C,Keller R

doi

10.1006/dbio.2002.0718

subject

Has Abstract

pub_date

2002-08-15 00:00:00

pages

220-39

issue

2

eissn

0012-1606

issn

1095-564X

pii

S0012160602907189

journal_volume

248

pub_type

杂志文章

相关文献

DEVELOPMENTAL BIOLOGY文献大全
  • Confocal quantification of cis-regulatory reporter gene expression in living sea urchin.

    abstract：:Quantification of GFP reporter gene expression at single cell level in living sea urchin embryos can now be accomplished by a new method of confocal laser scanning microscopy (CLSM). Eggs injected with a tissue-specific GFP reporter DNA construct were grown to gastrula stage and their fluorescence recorded as a series...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2006.06.016

    authors： Damle S,Hanser B,Davidson EH,Fraser SE

    更新日期：2006-11-15 00:00:00

  • Pax6 regulates regional development and neuronal migration in the cerebral cortex.

    abstract：:Mutations in the Pax6 gene disrupt telencephalic development, resulting in a thin cortical plate, expansion of proliferative layers, and the absence of the olfactory bulb. The primary defect in the neuronal cell population of the developing cerebral cortex was analysed by using mouse chimeras containing a mixture of w...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/s0012-1606(02)00046-5

    authors： Talamillo A,Quinn JC,Collinson JM,Caric D,Price DJ,West JD,Hill RE

    更新日期：2003-03-01 00:00:00

  • Identification of target genes for the Xenopus Hes-related protein XHR1, a prepattern factor specifying the midbrain-hindbrain boundary.

    abstract：:The midbrain-hindbrain boundary (MHB) acts as a local organizer in the development of the CNS in vertebrates. Previously, we identified an MHB-specific bHLH-WRPW transcriptional repressor gene, Xenopus Hes-related 1 (XHR1), which is initially expressed in the presumptive MHB (pre-MHB) region at the early gastrula stag...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2005.04.020

    authors： Takada H,Hattori D,Kitayama A,Ueno N,Taira M

    更新日期：2005-07-01 00:00:00

  • Repression of gene expression at the beginning of mouse development.

    abstract：:The transition from maternal to zygotic gene expression in the mouse occurs in the 2-cell embryo. Previous studies in which DNA was injected into 2-cell embryos revealed that transcription promoters and origins of DNA replication are strongly repressed in cleavage stage embryos unless linked to an embryo-responsive en...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.1995.1160

    authors： Henery CC,Miranda M,Wiekowski M,Wilmut I,DePamphilis ML

    更新日期：1995-06-01 00:00:00

  • Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth.

    abstract：:Epidermal growth factor (EGF), a low-molecular-weight polypeptide (G. Carpenter and S. Cohen, 1979, Annu. Rev. Biochem. 48, 193-216), stimulates the proliferation and keratinisation of cultured embryonic epidermis (S. Cohen, 1965, Dev. Biol. 12, 394-407) and promotes epidermal growth, thickening, and keratinisation wh...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(83)90243-9

    authors： Green MR,Basketter DA,Couchman JR,Rees DA

    更新日期：1983-12-01 00:00:00

  • Fluorescent protein expression driven by her4 regulatory elements reveals the spatiotemporal pattern of Notch signaling in the nervous system of zebrafish embryos.

    abstract：:Notch activation inhibits neuronal differentiation during development of the nervous system; however, the dynamic role of Notch signaling in individual cell lineages remains poorly understood. We have characterized 3.4 kb 5'-regulatory sequence of a Notch target gene, her4, and used it to drive fluorescent gene expres...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2006.10.020

    authors： Yeo SY,Kim M,Kim HS,Huh TL,Chitnis AB

    更新日期：2007-01-15 00:00:00

  • Assembly-disassembly of actin bundles in starfish oocytes: an analysis of actin-associated proteins in the isolated cortex.

    abstract：:One rapid response of starfish oocytes to the maturation-inducing hormone, 1-methyladenine (1-MA), is the formation of transient actin-filled spikes on the cell surface. The presence and distribution of G- and F-actin and several actin-associated proteins were examined in cortices isolated from oocytes before, during,...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(84)90140-4

    authors： Otto JJ,Schroeder TE

    更新日期：1984-02-01 00:00:00

  • Stabilization and expression of high levels of p53 during early development in Xenopus laevis.

    abstract：:We previously isolated a p53 cDNA from a Xenopus oocyte library. To determine if p53 has a function in the developmental period, we have studied its expression at the RNA and protein levels during the early development of Xenopus laevis. Two p53 transcripts (3 and 2.2 kb) are expressed from the beginning of Xenopus oo...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.1993.1230

    authors： Tchang F,Gusse M,Soussi T,Méchali M

    更新日期：1993-09-01 00:00:00

  • Progenitor targeting by adult stem cells in Ciona homeostasis, injury, and regeneration.

    abstract：:In the ascidian Ciona intestinalis, oral siphon amputation activates adult stem cell niches in the branchial sac to divide and dispatch migratory progenitor cells to a regeneration blastema at the site of injury. This study shows that progenitor cells derived from branchial sac stem cell niches have roles in homeostas...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2018.09.005

    authors： Jeffery WR

    更新日期：2019-04-15 00:00:00

  • Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation.

    abstract：:It has been difficult to examine the role of TGF-ß in post-natal tooth development due to perinatal lethality in many of the signaling deficient mouse models. To address the role of Tgfbr2 in postnatal tooth development, we generated a mouse in which Tgfbr2 was deleted in odontoblast- and bone-producing mesenchyme. Os...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2013.08.003

    authors： Wang Y,Cox MK,Coricor G,MacDougall M,Serra R

    更新日期：2013-10-01 00:00:00

  • Cell death of motoneurons in the chick embryo spinal cord. VIII. Motoneurons prevented from dying in the embryo persist after hatching.

    abstract：:A chronic neuromuscular blockade during those embryonic stages when naturally occurring spinal motoneuron death occurs, results in the prevention of this cell loss. The excess motoneurons are maintained as long as the neuromuscular blockade is continued; once embryonic neuromuscular activity resumes, however, the exce...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(84)90114-3

    authors： Oppenheim RW

    更新日期：1984-01-01 00:00:00

  • Sox9 is required for prostate development.

    abstract：:The mammalian prostate arises from the urogenital sinus and few factors have been identified to be important in the early stages of prostate development. In this study we show that the transcription factor Sox9 is expressed in the epithelia of all mouse prostatic lobes from the initial stages of their development. We ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2008.01.030

    authors： Thomsen MK,Butler CM,Shen MM,Swain A

    更新日期：2008-04-15 00:00:00

  • Subcellular trafficking of the nuclear receptor COUP-TF in the early embryonic cell cycle.

    abstract：:The nuclear receptor SpCOUP-TF is the highly conserved sea urchin homologue of the COUP family of transcription factors. Previous results from our laboratory demonstrated that SpCOUP-TF transcripts are localized in the egg and asymmetrically distributed in the early embryonic blastomeres (A. Vlahou et al., 1996, Devel...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.1999.9456

    authors： Vlahou A,Flytzanis CN

    更新日期：2000-02-15 00:00:00

  • Effects of phlorizin and ouabain on the polarity of mouse 4-cell/16-cell stage blastomere heterokaryons.

    abstract：:Cell polarity is thought to be required for the efficient production of nascent blastocoele fluid, which begins at the 16-cell stage of mouse preimplantation development. In this study the 4-cell/16-cell blastomere heterokaryon was used to test the hypothesis that solute transport across the apical membrane domain ind...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(89)90041-9

    authors： Wiley LM,Obasaju MF

    更新日期：1989-06-01 00:00:00

  • Regulation of Ci and Su(fu) nuclear import in Drosophila.

    abstract：:The Hedgehog (Hh) signal transduction pathway plays a central role in the development of invertebrates and vertebrates. While much is known about the pathway, the role of Suppressor of fused (Su(fu)), a component of the pathway's signaling complex has remained enigmatic. Previous studies have linked Su(fu) to the cyto...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2006.02.050

    authors： Sisson BE,Ziegenhorn SL,Holmgren RA

    更新日期：2006-06-01 00:00:00

  • Protein kinase D regulates metabolism and growth by controlling secretion of insulin like peptide.

    abstract：:Mechanisms coupling growth and metabolism are conserved in Drosophila and mammals. In metazoans, such coupling is achieved across tissue scales through the regulated secretion of chemical messengers such as insulin that control the metabolism and growth of cells. Although the regulated secretion of Insulin like peptid...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2017.12.008

    authors： Ashe S,Malhotra V,Raghu P

    更新日期：2018-02-01 00:00:00

  • Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1.

    abstract：:During early vertebrate development, ANF homeobox genes are expressed in the prospective forebrain. Their regulation is essential for correct morphogenesis and function of the prosencephalon. We identified a 1-kb fragment upstream of the chicken GANF gene sufficient to drive lacZ expression in the endogenous expressio...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2004.01.044

    authors： Spieler D,Bäumer N,Stebler J,Köprunner M,Reichman-Fried M,Teichmann U,Raz E,Kessel M,Wittler L

    更新日期：2004-05-15 00:00:00

  • A unique role for 6-O sulfation modification in zebrafish vascular development.

    abstract：:Heparan sulfate proteoglycans are important modulators of growth factor signaling in a variety of patterning processes. Secreted growth factors that play critical roles in angiogenesis bind to heparan sulfate, and this association is affected by 6-O-sulfation of the heparan sulfate chains. Addition of 6-O-sulfate is c...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2005.05.032

    authors： Chen E,Stringer SE,Rusch MA,Selleck SB,Ekker SC

    更新日期：2005-08-15 00:00:00

  • The alphaBbetaC integrin is expressed on the surface of the sea urchin egg and removed at fertilization.

    abstract：:Integrins are expressed on the surface of some vertebrate eggs where they are thought to have a role in fertilization. The objective of this study is to determine if integrins are expressed on sea urchin eggs. The alphaB and betaC subunits were cloned using the homology polymerase chain reaction. Monoclonal and polycl...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.2000.9910

    authors： Murray G,Reed C,Marsden M,Rise M,Wang D,Burke RD

    更新日期：2000-11-15 00:00:00

  • The oblique muscle organizer in Hirudo medicinalis, an identified embryonic cell projecting multiple parallel growth cones in an orderly array.

    abstract：:The oblique muscle layer in the leech body wall is built upon the processes of a unique identified embryonic cell, the Comb- or C-cell. Each C-cell is composed of a spindle-shaped soma that projects approximately 70 parallel processes through the developing body wall at an angle oblique to the long axis. The morphogen...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(91)90342-z

    authors： Jellies J,Kristan WB Jr

    更新日期：1991-11-01 00:00:00

  • Cyclical generation and degeneration of organs in a colonial urochordate involves crosstalk between old and new: a model for development and regeneration.

    abstract：:Botryllus schlosseri is a colonial marine urochordate in which all adult organisms (called zooids) in a colony die synchronously by apoptosis (programmed cell death) in cyclical fashion. During this death phase called takeover, cell corpses within the dying organism are engulfed by circulating phagocytic cells. The "o...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.2002.0772

    authors： Lauzon RJ,Ishizuka KJ,Weissman IL

    更新日期：2002-09-15 00:00:00

  • Coordinate regulation of the expression of axonal proteins by the axonal microenvironment.

    abstract：:The axonal functions that act in the formation of the neuronal network have been shown to occur in close interdependence with the tissue that surrounds the growing axons. However, little is known about the molecular building blocks underlying axonal functions, although more than 400 axonal proteins have been identifie...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(86)90090-4

    authors： Sonderegger P,Lemkin PF,Lipkin LE,Nelson PG

    更新日期：1986-11-01 00:00:00

  • Restricted response of mesencephalic neural crest to sympathetic differentiation signals in the trunk.

    abstract：:Lineage diversification in the vertebrate neural crest may occur via instructive signals acting on pluripotent cells, and/or via early specification of subpopulations towards particular lineages. Mesencephalic neural crest cells normally form cholinergic parasympathetic neurons in the ciliary ganglion, while trunk neu...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2004.10.024

    authors： Lee VM,Bronner-Fraser M,Baker CV

    更新日期：2005-02-01 00:00:00

  • FEATURE.

    abstract：:Copyright ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.1998.8954

    authors：

    更新日期：1998-07-15 00:00:00

  • Ubx dynamically regulates Dpp signaling by repressing Dad expression during copper cell regeneration in the adult Drosophila midgut.

    abstract：:The gastrointestinal (GI) tract of metazoans is lined by a series of regionally distinct epithelia. To maintain structure and function of the GI tract, regionally diversified differentiation of somatic stem cell (SC) lineages is critical. The adult Drosophila midgut provides an accessible model to study SC regulation ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2016.08.027

    authors： Li H,Qi Y,Jasper H

    更新日期：2016-11-15 00:00:00

  • A newly identified type of attachment cell is critical for normal patterning of chordotonal neurons.

    abstract：:This work describes unknown aspects of chordotonal organ (ChO) morphogenesis revealed in post-embryonic stages through the use of new fluorescently labeled markers. We show that towards the end of embryogenesis a hitherto unnoticed phase of cell migration commences in which the cap cells of the ventral ChOs elongate a...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2016.01.009

    authors： Halachmi N,Nachman A,Salzberg A

    更新日期：2016-03-01 00:00:00

  • Evidence that protein kinase C (PKC) participates in the meiosis I to meiosis II transition in mouse oocytes.

    abstract：:Oocytes from LTXBO mice exhibit a delayed entry into anaphase I and frequently enter interphase after the first meiotic division. This unique oocyte model was used to test the hypothesis that protein kinase C (PKC) may regulate the meiosis I-to-meiosis II transition. PKC activity was detected in LTXBO oocytes at proph...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.2001.0311

    authors： Viveiros MM,Hirao Y,Eppig JJ

    更新日期：2001-07-15 00:00:00

  • The cortical granule serine protease CGSP1 of the sea urchin, Strongylocentrotus purpuratus, is autocatalytic and contains a low-density lipoprotein receptor-like domain.

    abstract：:Trypsin-like activity is secreted from eggs of many species at fertilization, and this activity is believed to be critical for the block to polyspermy. Here we show that a cortical granule serine protease of sea urchins is the major and perhaps only protease family member important for fertilization. Zymography assays...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.1999.9299

    authors： Haley SA,Wessel GM

    更新日期：1999-07-01 00:00:00

  • Developmental regulation and properties of the cGMP-specific phosphodiesterase in Dictyostelium discoideum.

    abstract：:A simple assay has been developed to measure cGMP-specific phosphodiesterase (cGPD) activity in crude soluble extracts of amoebae of Dictyostelium discoideum. When amoebae of different wild-type strains were starved on buffered agar, all strains exhibited an 8- to 12-fold increase in cGMP-specific hydrolyzing activity...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(84)90026-5

    authors： Coukell MB,Cameron AM,Pitre CM,Mee JD

    更新日期：1984-05-01 00:00:00

  • MAPK/ERK activity is required for the successful progression of mitosis in sea urchin embryos.

    abstract：:Using sea urchin embryos, we demonstrate that the MEK/MAPK/ERK cascade is essential for the proper progression of the cell cycle. Activation of a limited fraction of MAPK/ERK is required between S-phase and M-phase. Neither DNA replication nor CDK1 activation are impacted by the inhibition of this small active MAPK/ER...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2016.11.018

    authors： Mulner-Lorillon O,Chassé H,Morales J,Bellé R,Cormier P

    更新日期：2017-01-15 00:00:00