Abstract:
:A 48-year-old woman with small-cell lung cancer received combined chemotherapy consisting of cisplatin (CDDP) and etoposide (Vp-16). Although the gustatory threshold in the glossopharyngeal nerve area was normal (14 dB) before chemotherapy, it rose to 22 dB on day 8 of chemotherapy, and it could not be measured, because of severe gustatory disorder, from day 15 to day 29. In the chorda tympani nerve area, the threshold was normal until day 15, but it could not be measured on day 29. This gustatory disorder continued for 2 more months, until the time of the patient's discharge. Although gustatory disorder caused by anticancer drugs has been reported as a rare side effect, this may be because it has been reported as appetite loss, and it may happen more frequently than reported cases would suggest. As gustatory disorder reduces the patient's quality of life, the presence of this side effect should be given more serious consideration.
journal_name
Int J Clin Oncoljournal_title
International journal of clinical oncologyauthors
Minakata Y,Yamagata T,Nakanishi H,Nishimoto T,Nakanishi M,Mune M,Yukawa Sdoi
10.1007/s101470200017subject
Has Abstractpub_date
2002-04-01 00:00:00pages
124-7issue
2eissn
1341-9625issn
1437-7772journal_volume
7pub_type
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journal_title:International journal of clinical oncology
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journal_title:International journal of clinical oncology
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journal_title:International journal of clinical oncology
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