NAADP: an atypical Ca2+-release messenger?

Abstract:

:Recently, nicotinic acid adenine dinucleotide phosphate (NAADP) has been shown, using different techniques, to mobilize intracellular Ca2+ stores in invertebrate, lower vertebrate, plant and mammalian cells. This endogenous molecule might play an atypical role in Ca2+ signalling by coordinating the responses of other Ca2+-releasing messengers. Furthermore, radioligand binding experiments have provided an insight into how desensitization of the NAADP receptor might occur.

journal_name

Trends Pharmacol Sci

authors

Genazzani AA,Billington RA

doi

10.1016/s0165-6147(00)01990-8

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

165-7

issue

4

eissn

0165-6147

issn

1873-3735

pii

S0165-6147(00)01990-8

journal_volume

23

pub_type

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