Abstract:
:Recently, nicotinic acid adenine dinucleotide phosphate (NAADP) has been shown, using different techniques, to mobilize intracellular Ca2+ stores in invertebrate, lower vertebrate, plant and mammalian cells. This endogenous molecule might play an atypical role in Ca2+ signalling by coordinating the responses of other Ca2+-releasing messengers. Furthermore, radioligand binding experiments have provided an insight into how desensitization of the NAADP receptor might occur.
journal_name
Trends Pharmacol Scijournal_title
Trends in pharmacological sciencesauthors
Genazzani AA,Billington RAdoi
10.1016/s0165-6147(00)01990-8subject
Has Abstractpub_date
2002-04-01 00:00:00pages
165-7issue
4eissn
0165-6147issn
1873-3735pii
S0165-6147(00)01990-8journal_volume
23pub_type
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journal_title:Trends in pharmacological sciences
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